| Memorial Hermann Health System | 501(c)(3) | 1973 | $8.56 billion | $14.87 billion | 2025-06 |
| The Methodist Hospital | 501(c)(3) | 2010 | $3.60 billion | $11.86 billion | 2024-12 |
| Legacy Community Health Services Inc | 501(c)(3) | 2006 | $453.8 million | $139.3 million | 2025-06 |
| Memorial Hermann Medical Group | 501(c)(3) | 2008 | $354.7 million | $191.3 million | 2025-06 |
| U T Physicians | 501(c)(3) | 1997 | $179.2 million | $171.5 million | 2019-08 |
| Methodist Hospital | 501(c)(3) | 2010 | $150.9 million | $1.01 billion | 2024-12 |
| Texas Medical Center | 501(c)(3) | 1948 | $141.5 million | $903.1 million | 2024-12 |
| Gulf Coast Regional Blood Center | 501(c)(3) | 1975 | $132.7 million | $186 million | 2024-12 |
| Memorial Hermann Pharmacy Services LLC | 501(c)(3) | 2018 | $130.3 million | $22.6 million | 2025-06 |
| Memorial Hermann Hospital Based Physician Group | 501(c)(3) | 2022 | $108.4 million | $11.6 million | 2025-06 |
| Lifegift Organ Donation Center | 501(c)(3) | 1998 | $104.1 million | $104.7 million | 2024-12 |
| Texas Medical Center Central Heat and Cooling Services Corp | 501(c)(3) | 2002 | $97.7 million | $541.7 million | 2025-08 |
| Episcopal Health Foundation | 501(c)(3) | 2013 | $88.7 million | $1.22 billion | 2024-12 |
| The Menninger Clinic | 501(c)(3) | 2003 | $66.3 million | $71.3 million | 2024-12 |
| Memorial Hermann Foundation | 501(c)(3) | 2026 | $63.3 million | $208.2 million | 2025-06 |
| MHS Physicians of Texas | 501(c)(3) | 1996 | $58.4 million | $13.6 million | 2025-06 |
| Asian American Health Coalition of the Greater Houston Area | 501(c)(3) | 2001 | $38.2 million | $49.5 million | 2025-12 |
| Betterhealth A Planned Parenthood Partnership | 501(c)(3) | 2002 | $31.9 million | $6.1 million | 2025-06 |
| Planned Parenthood Gulf Coast Inc | 501(c)(3) | 1966 | $24.8 million | $51.4 million | 2025-06 |
| Seven Acres Jewish Senior Care Services Inc | 501(c)(3) | 1944 | $18 million | $31.5 million | 2025-08 |
| Institute for Rehabilitation & Research Foundation | 501(c)(3) | 1987 | $14.5 million | $32.2 million | 2025-12 |
| Ibn Sina Foundation Inc | 501(c)(3) | 2002 | $14.2 million | $21.3 million | 2024-12 |
| Legacy Community Pharmacy Services | 501(c)(3) | 2020 | $11.9 million | $5.8 million | 2025-06 |
| Houston Community Health Centers Inc | 501(c)(3) | 2000 | $11.7 million | $11.5 million | 2024-12 |
| Southeast Texas Regional Advisory Council | 501(c)(3) | 1995 | $9.7 million | $8.1 million | 2024-08 |
| Sheldon Community Volunteer Fire & Rescue Inc | 501(c)(3) | 1996 | $9.4 million | $607,976 | 2025-12 |
| Ronald McDonald House Charities Greater Houston Inc | 501(c)(3) | 1983 | $9.2 million | $27.4 million | 2024-12 |
| Christus Foundation for Healthcare | 501(c)(3) | 1966 | $8.9 million | $92.2 million | 2025-06 |
| Baylor College of Medicine International Pediatric Aids Initi | 501(c)(3) | 2006 | $8.8 million | $555,293 | 2025-06 |
| Sky High for Kids Inc | 501(c)(3) | 2008 | $8.3 million | $3.2 million | 2024-12 |
| The Menninger Clinic Foundation | 501(c)(3) | 2003 | $7.5 million | $62 million | 2024-12 |
| TMC3 Development Corporation | 501(c)(3) | 2020 | $7.2 million | $203 million | 2024-12 |
| Healthconnect Texas | 501(c)(3) | 2012 | $7.1 million | $6.9 million | 2024-12 |
| South Lake Houston Emergency Medical Services | 501(c)(3) | 2002 | $6.3 million | $3.3 million | 2022-12 |
| The Cullen Trust for Health Care | 501(c)(3) | 1978 | $5.2 million | $126.1 million | 2024-12 |
| The Beacon of Downtown Houston | 501(c)(3) | 2003 | $4.9 million | $3.3 million | 2024-12 |
| Bee Busy Wellness Center | 501(c)(3) | 2009 | $4.5 million | $3.2 million | 2024-12 |
| Sunshine Kids Foundation | 501(c)(3) | 1982 | $4.3 million | $12.6 million | 2025-12 |
| Fundacion Latinoamericana de Accion Social Inc | 501(c)(3) | 1995 | $3.9 million | $1.4 million | 2024-12 |
| Texas Medical Center Foundation | 501(c)(3) | 2015 | $3.4 million | $3.9 million | 2024-12 |
| Legacy Community Health Endowment Inc | 501(c)(3) | 2006 | $2.5 million | $29.3 million | 2025-06 |
| Noras Gift Foundation Inc | 501(c)(3) | 1999 | $2.5 million | $18.5 million | 2024-12 |
| CHN Medical Support Systems | 501(c)(3) | 2021 | $2.1 million | $1.4 million | 2025-12 |
| Foundation for Education & Research in Vision Inc | 501(c)(3) | 1957 | $1.7 million | $12 million | 2025-08 |
| Care Care Net Pregnancy Center of Houst | 501(c)(3) | 1993 | $1.7 million | $4.4 million | 2024-12 |
| Mexico Medical Missions | 501(c)(3) | 2007 | $1.6 million | $1.2 million | 2025-12 |
| Health Care for Special Populations | 501(c)(3) | 2012 | $1.5 million | $99,387 | 2024-12 |
| Houston House Foundation | 501(c)(3) | 1990 | $1.4 million | $26.8 million | 2024-12 |
| Houston Coalition for Life | 501(c)(3) | 2002 | $1.4 million | $1.3 million | 2024-12 |
| The Immunization Partnership | 501(c)(3) | 2002 | $1.3 million | $890,918 | 2025-09 |
| Casa El Buen Samaritano | 501(c)(3) | 2007 | $1.1 million | $1.8 million | 2024-12 |
| Nick Finnegan Counseling Center Foundation | 501(c)(3) | 2019 | $907,509 | $1.4 million | 2025-12 |
| The Living Bank International | 501(c)(3) | 1968 | $763,022 | $4.4 million | 2025-06 |
| Toys Fore TCH Kids | 501(c)(3) | 2019 | $679,177 | $72,725 | 2024-12 |
| Shifa Healthcare & Community Services USA Inc | 501(c)(3) | 2012 | $618,421 | $181,398 | 2025-12 |
| Loving Care Personal Care Home | 501(c)(3) | 1995 | $598,921 | $777,458 | 2024-12 |
| Cancer Cures 4 Kids | 501(c)(3) | 2015 | $595,999 | $178,897 | 2024-12 |
| Albert Schweitzer Fellowship Houston-Galveston | 501(c)(3) | 2014 | $559,868 | $222,726 | 2025-12 |
| Carl McCain Memorial Foundation | 501(c)(3) | 1979 | $518,915 | $3.3 million | 2024-12 |
| Foundation for Teen Health | 501(c)(3) | 1991 | $465,623 | $507,364 | 2025-12 |
| Crisis Pregnancy Center of Southwest Houston Inc | 501(c)(3) | 1986 | $425,487 | $142,086 | 2025-12 |
| Camp H-Town | 501(c)(3) | 2019 | $421,016 | $666,062 | 2025-12 |
| Living Hope Wheelchair Association | 501(c)(3) | 2009 | $419,263 | $472,217 | 2024-12 |
| Upward Bound Community Development Corporation | 501(c)(3) | 2014 | $415,044 | $621,201 | 2025-12 |
| Uhphealth Inc | 501(c)(3) | 2015 | $414,126 | $518,426 | 2024-12 |
| Enhancing Skills for Life | 501(c)(3) | 2019 | $379,688 | $177,939 | 2025-12 |
| Santa Maria Hostel Foundation | 501(c)(3) | 2007 | $355,162 | $5.6 million | 2025-08 |
| Trust CHW | 501(c)(3) | 2024 | $331,457 | $272,271 | 2024-12 |
| Dans House of Hope Inc | 501(c)(3) | 2010 | $310,300 | $813,993 | 2025-12 |
| Houston Medical Forum | 501(c)(3) | 2022 | $302,826 | $994,976 | 2024-12 |
| Mi Promotor de Salud | 501(c)(3) | 2023 | $301,830 | $142,686 | 2025-12 |
| Native Healthcare Center | 501(c)(3) | 2022 | $284,927 | $11,316 | 2025-12 |
| Hope Health and Wellness Center Qalicb | 501(c)(3) | 2021 | $233,697 | $24.1 million | 2025-12 |
| Rehabilitation Services Volunteer Project | 501(c)(3) | 2013 | $224,740 | $364,985 | 2024-12 |
| Lone Star Oncology | 501(c)(3) | 2024 | $215,350 | $5,879 | 2024-12 |
| Bering Omega Community Services | 501(c)(3) | 1999 | $204,447 | $3.6 million | 2024-12 |
| Lions Eye Bank Foundation | 501(c)(3) | 1988 | $200,396 | $4.7 million | 2025-06 |
| Physician Transformation Institute Inc | 501(c)(3) | 2023 | $198,731 | $17,070 | 2025-01 |
| Texas Fire Fighters Home | 501(c)(3) | 2013 | $193,630 | $261,749 | 2025-06 |
| Greater Houston Area Health Education Center Inc | 501(c)(3) | 2023 | $188,849 | $62,827 | 2025-09 |
| Houston Ground Angels | 501(c)(3) | 2005 | $173,749 | $280,723 | 2025-12 |
| Al-Shifa Institution of Eye Care | 501(c)(3) | 2024 | $159,337 | $159,195 | 2024-12 |
| Ferguson Business Associates | 501(c)(3) | 2010 | $157,951 | $189,366 | 2024-12 |
| El Camino Global Foundation | 501(c)(3) | 2015 | $151,547 | $5,007 | 2025-12 |
| Healthcare Innovators Professional Society | 501(c)(3) | 2018 | $143,328 | $60,499 | 2024-12 |
| Vecino Centers for Health Services | 501(c)(3) | 2019 | $140,548 | $5 million | 2024-12 |
| Ill Have What Shes Having | 501(c)(3) | 2020 | $140,263 | $145,392 | 2024-12 |
| Kids Unlimited Foundation | 501(c)(3) | 1995 | $133,806 | $193,978 | 2025-06 |
| National Spinal Cord Injury Association Houston | 501(c)(3) | 2015 | $131,000 | $129,121 | 2025-12 |
| Society for Neuro-Oncology Foundation | 501(c)(3) | 2025 | $130,006 | $104,680 | 2025-06 |
| Ignite Health | 501(c)(6) | 2020 | $124,679 | $36,471 | 2025-12 |
| The Preinatal Unit for Systems of Health | 501(c)(3) | 2020 | $124,154 | $95,738 | 2025-06 |
| Kel Strong Mabatah Foundation | 501(c)(3) | 2023 | $104,853 | $45,988 | 2025-12 |
| Lions Eye Bank of Texas | 501(c)(3) | 2014 | $104,268 | $257,948 | 2025-06 |
| Build Them Up Foundation | 501(c)(3) | 2022 | $104,096 | $10,330 | 2024-12 |
| Indian Doctors Club Charitable Foundation Inc | 501(c)(3) | 1999 | $103,184 | $483,408 | 2025-12 |
| Friday Harbour | 501(c)(3) | 2015 | $89,994 | $41,535 | 2025-12 |
| Alliance of Cardiovascular Researchers | 501(c)(3) | 2020 | $86,165 | $346,485 | 2024-12 |
| Sisters in Public Health Inc | 501(c)(3) | 2021 | $82,463 | $48,443 | 2025-12 |
| Miles 4 Matthew | 501(c)(3) | 2023 | $78,533 | $43,441 | 2025-12 |
| Prosalud Inc | 501(c)(3) | 2005 | $74,052 | $21,933 | 2025-12 |
| Lesbian Health Initiative of Houston Texas | 501(c)(3) | 1994 | $70,830 | $1 | 2023-08 |
| Pampered Pink | 501(c)(3) | 2025 | $64,562 | $64,562 | 2024-12 |
| BTR Caring for Kids | 501(c)(3) | 2023 | $62,223 | $49,405 | 2025-12 |
| Hamilton Health Box Foundation Inc | 501(c)(3) | 2024 | $60,000 | $35,552 | 2024-12 |
| Texas Education and Research Foundation for Shoulder & Elbow Su | 501(c)(3) | 2018 | $58,080 | $58,711 | 2024-12 |
| Setrac Foundation | 501(c)(3) | 2019 | $50,625 | $1.4 million | 2025-08 |
| Diverse Dental Society | 501(c)(3) | 2021 | $45,000 | $82,755 | 2025-12 |
| PGX Global Foundation | 501(c)(3) | 2022 | $44,443 | $632 | 2023-12 |
| Crystal Foundation | 501(c)(3) | 1992 | $31,575 | $16,185 | 2025-12 |
| Gabriel Institute Inc | 501(c)(3) | 2007 | $30,000 | $107,660 | 2024-12 |
| Perez Foundation for Health and Hope | 501(c)(3) | 2025 | $27,266 | $27,266 | 2025-12 |
| Disability Inventions Sezual Inc | 501(c)(3) | 2023 | $23,213 | $1 | 2024-12 |
| Global Liberation Outreach- Faith Clinic | 501(c)(3) | 2019 | $21,000 | $1 | 2024-12 |
| Pride Charities Inc | 501(c)(3) | 1992 | $16,443 | $25,299 | 2024-12 |
| Arab American Medical Association | 501(c)(3) | 2000 | $12,246 | $55,499 | 2024-12 |
| Gayle Wells Foundation for Early Onset Alzheimer S & Care | 501(c)(3) | 2013 | $7,577 | $6,728 | 2023-12 |
| Cautious Relief Inc | 501(c)(3) | 2018 | $6,500 | $19,545 | 2024-12 |
| Body Balance Foundation | 501(c)(3) | 2018 | $6,250 | $6,325 | 2024-12 |
| Homero Martinez Heart Failure Foundation | 501(c)(3) | 2024 | $5,546 | $1 | 2024-12 |
| Inspiring Hope and Love Organization | 501(c)(3) | 2025 | $5,004 | $1 | 2025-12 |
| A Global Voice for Autism Inc | 501(c)(3) | 2020 | $4,704 | $2,460 | 2024-12 |
| Fourfold Heart | 501(c)(3) | 2025 | $1,621 | $200 | 2025-12 |
| Neurostronger Inc | 501(c)(3) | 2024 | $1,578 | $1,281 | 2025-12 |
| Glucose Guide | 501(c)(3) | 2025 | $838 | $141 | 2025-12 |
| Advocates of the Vergie Reid Community Project Inc | 501(c)(3) | 2008 | $500 | $1 | 2022-12 |
| Aco Triple Aim Providers Inc | 501(c)(3) | 2015 | $1 | $2,044 | 2024-12 |
| 1-2-3-Breathe | 501(c)(3) | 2014 | $0 | $0 | 2025-12 |
| 10X Blessings Foundation | 501(c)(3) | 2021 | $0 | $0 | 2025-12 |
| 2ND Wind Experience Foundation | 501(c)(3) | 2026 | | | |
| 369 Angels for Humanity | 501(c)(3) | 2025 | $0 | $0 | 2025-12 |
| 4boundlesscare Corp | 501(c)(3) | 2025 | | | |
| 9 Months of 5K | 501(c)(3) | 2022 | $0 | $0 | 2025-12 |
| Abc Health Connection Inc | 501(c)(3) | 2015 | $0 | $0 | 2025-12 |
| Affiliated Medical Services | 501(c)(3) | 1988 | $0 | $1 | 2025-06 |
| African American Health Coalition Houston Metropolitan Area Inc | 501(c)(3) | 2022 | $0 | $0 | 2024-12 |
| African Blindness Prevention Mission | 501(c)(3) | 1994 | $0 | $0 | 2024-12 |
| Aka Family Foundation | 501(c)(3) | 2021 | | $1 | 2025-12 |
| Aliados Por Venezuela | 501(c)(3) | 2021 | $0 | $0 | 2025-12 |
| American Association of Somatic Sexology Inc | 501(c)(3) | 2023 | $0 | $0 | 2026-01 |
| American Institute of Clinical Docu Mentation Integrity | 501(c)(3) | 2025 | | | |
| American Society for Kids Inc | 501(c)(3) | 2006 | $0 | $0 | 2024-12 |
| Angels Life Skills Center Inc | 501(c)(3) | 2017 | $0 | $0 | 2024-12 |
| Arc Angels | 501(c)(3) | 2019 | $0 | $0 | 2024-12 |
| Arsenal Foundation Inc | 501(c)(3) | 2025 | $0 | $0 | 2025-12 |
| Association of Clinical Research Professionals | 501(c)(3) | 1984 | $0 | $0 | 2024-12 |
| Ave Acompanamiento Y Visitas A Enfe Rmos | 501(c)(3) | 2026 | | | |
| Avest Care | 501(c)(3) | 2019 | $0 | $0 | 2025-12 |
| B I R T H | 501(c)(3) | 2005 | $0 | $0 | 2025-12 |
| BRSF Skate | 501(c)(3) | 2022 | $0 | $0 | 2025-12 |
| Baylor College of Medicine Health Care | 501(c)(3) | 1996 | $0 | $0 | 2025-06 |
| Beesafe Kids | 501(c)(3) | 2021 | $0 | $0 | 2024-12 |
| Begin Again Isa 40 31 | 501(c)(3) | 2022 | $0 | $0 | 2024-12 |
| Beyond Limits Foundation | 501(c)(3) | 2025 | | | |
| Birth Houston | 501(c)(3) | 2023 | $0 | $0 | 2025-12 |
| Blossomflow Empowerment Foundation | 501(c)(3) | 2024 | | | |
| Bluejay Empowered Fitness | 501(c)(3) | 2025 | $0 | $0 | 2025-12 |
| Bolden Foundation | 501(c)(3) | 2026 | | | |
| Bridgiing Resources | 501(c)(3) | 2021 | $0 | $0 | 2025-12 |
| Brightway Cares | 501(c)(3) | 2025 | $0 | $0 | 2025-12 |
| Brotherhood Health | 501(c)(3) | 2024 | | | |
| CR38V3 M1ND5 Inc | 501(c)(3) | 2020 | $0 | $0 | 2026-01 |
| Cancer Crisis Fund | 501(c)(3) | 2009 | $0 | $0 | 2025-12 |
| Caring 4 U Mobile Clinic Inc | 501(c)(3) | 2024 | | | |
| Caring Critters Inc | 501(c)(3) | 1992 | $0 | $0 | 2025-10 |
| Catch Greater Houston | 501(c)(3) | 2025 | | | |
| Christians Miracle Child Foundation | 501(c)(3) | 2025 | $0 | $0 | 2024-12 |
| Cliffords Animal Rescue Transportation Inc | 501(c)(3) | 2019 | $0 | $0 | 2023-12 |
| Community Healthcare Collective | 501(c)(3) | 2026 | | | |
| Community Outreach Clinic | 501(c)(3) | 2012 | $0 | $0 | 2024-12 |
| Connected By Chiropractic | 501(c)(3) | 2026 | $0 | $0 | 2025-06 |
| Cuidarte | 501(c)(3) | 2024 | $0 | $0 | 2023-12 |
| DFW Nurse Connect Limited | 501(c)(3) | 2025 | | | |
| DNF Diabetes | 501(c)(3) | 2012 | $0 | $0 | 2024-06 |
| Danz Fuzion 5 | 501(c)(3) | 2025 | $0 | $0 | 2025-12 |
| Daughters of Virtue and Excellence Ministry | 501(c)(3) | 2002 | $0 | $0 | 2025-12 |
| Despertar Global Inc | 501(c)(3) | 2026 | | | |
| Dhiru Prabhu Canter Foundation | 501(c)(3) | 2014 | | $11,381 | 2023-12 |
| Divine Grace Medical Missionaries Inc | 501(c)(3) | 2023 | $0 | $0 | 2024-12 |
| Eagles Lift Ministries | 501(c)(3) | 2026 | $0 | $0 | 2025-12 |
| Ec for Houston | 501(c)(3) | 2024 | $0 | $1 | 2024-12 |
| Educare Foundation Inc | 501(c)(3) | 2022 | $0 | $1 | 2023-12 |
| Ewe Healing Inc | 501(c)(3) | 2026 | | | |
| Eye Can Network Inc | 501(c)(3) | 2020 | $0 | $0 | 2025-12 |
| FCN Foundation | 501(c)(3) | 2021 | $0 | $0 | 2025-12 |
| Family Faith Healthcare Clinic Inc | 501(c)(3) | 2022 | $0 | $0 | 2025-12 |
| Food2fix | 501(c)(3) | 2024 | | | |
| Foundation for the Localization and Innovation of Global Health Techno | 501(c)(3) | 2024 | $0 | $3,608 | 2025-09 |
| Friends Helping Friends | 501(c)(3) | 2002 | $0 | $0 | 2025-12 |
| Friends of the Fetal Center | 501(c)(3) | 2023 | $0 | $0 | 2025-12 |
| Friendship Smile | 501(c)(3) | 2023 | $0 | $0 | 2025-12 |
| Fully Informed Conversations Inc | 501(c)(3) | 2025 | | $30,509 | 2025-12 |
| Functional Life Performance Foundation | 501(c)(3) | 2020 | $0 | $0 | 2025-12 |
| Funding Lymphatic Uniflow Innovation and Discovery Foundatio | 501(c)(3) | 2025 | | | |
| Futuro USA Inc | 501(c)(3) | 2018 | $0 | $0 | 2024-12 |
| Gene Therapy and Radiation Research Foundation | 501(c)(3) | 2024 | $0 | $0 | 2025-12 |
| Gerontological Advanced Practice Nurses Association | 501(c)(6) | 2014 | $0 | $0 | 2025-12 |
| Ghana Brain Tumor Foundation | 501(c)(3) | 2025 | $0 | $0 | 2025-12 |
| Gifted Hearts Inc | 501(c)(3) | 2021 | $0 | $0 | 2025-12 |
| Glitchy Brain | 501(c)(3) | 2024 | $0 | $0 | 2024-12 |
| Global Clinical Engineering Alliance | 501(c)(3) | 2021 | $0 | $0 | 2025-06 |
| Global Heath and Wellness | 501(c)(3) | 2023 | $0 | $0 | 2023-12 |
| Global Village Healthcare Foundation | 501(c)(3) | 2025 | $0 | $0 | 2025-12 |
| Gme Missions Inc | 501(c)(3) | 2008 | $0 | $0 | 2024-12 |
| Goodest Care | 501(c)(3) | 2022 | $0 | $0 | 2024-12 |
| Grace Foundation for Maternal Health and Wellness | 501(c)(3) | 2024 | $0 | $0 | 2024-12 |
| Gulf Coast Blood Foundation | 501(c)(3) | 2026 | | | |
| Gyneration Mobile Gynecology | 501(c)(3) | 2023 | $0 | $0 | 2025-12 |
| HCV Education and Care Center of Houston | 501(c)(3) | 2025 | $0 | $0 | 2025-12 |
| HFB Core Support | 501(c)(3) | 2026 | | | |
| Hands of Blessings | 501(c)(3) | 2024 | | | |
| Hands of Transformation Foundation | 501(c)(3) | 2026 | | | |
| Harris Center for Integrated Care | 501(c)(3) | 2024 | | | |
| Harris County Medical Society Alliance | 501(c)(6) | 1974 | $0 | $0 | 2025-12 |
| Heal the Sick | 501(c)(3) | 2025 | $0 | $0 | 2025-12 |
| Healing Horizons Inc | 501(c)(3) | 2026 | | | |
| Healing Lives Health and Learning Center | 501(c)(3) | 2019 | $0 | $0 | 2024-12 |
| Health Equity Collective Inc | 501(c)(3) | 2023 | $0 | $0 | 2025-12 |
| Health Hotspot | 501(c)(3) | 2026 | | | |
| Health in Your Hands Diagnostics | 501(c)(3) | 2025 | $0 | $0 | 2025-12 |
| Healthy Houston Healthy Texas Healthy America Foundation | 501(c)(3) | 2005 | $0 | $0 | 2025-12 |
| Hectordamian Foundation Ruvalcaba-Amador Non Profit Org | 501(c)(3) | 2023 | $0 | $0 | 2025-12 |
| Her Choice | 501(c)(3) | 2024 | $0 | $0 | 2025-12 |
| Honduras Dental Project | 501(c)(3) | 2005 | $0 | $0 | 2023-12 |
| Honeymiel Healthcare Inc | 501(c)(3) | 2022 | $0 | $0 | 2024-12 |
| Hopewell Supportive Services Inc | 501(c)(3) | 2019 | $0 | $0 | 2025-12 |
| Houston Area Lactation Consultants & Educators Association | 501(c)(3) | 2000 | $0 | $0 | 2026-06 |
| Houston Asian American Dental Society | 501(c)(3) | 2014 | $0 | $0 | 2025-12 |
| Houston Gynecological & Obsterical Society | 501(c)(3) | 2002 | $0 | $0 | 2025-12 |
| Houston Kali Bari and Devjyoti Temple | 501(c)(3) | 2024 | | $113,599 | 2025-12 |
| Houston Korean Nurse Association | 501(c)(3) | 2013 | $0 | $0 | 2025-12 |
| Human Health Foundation | 501(c)(3) | 2016 | $0 | $0 | 2024-12 |
| Ideserve Advocacy for Autism Inc | 501(c)(3) | 2024 | $0 | $0 | 2025-12 |
| Ifitedunu Medical and Allied Professional Association Imapa | 501(c)(3) | 2024 | $0 | $0 | 2025-12 |
| Inclusive Minds Foundation Co | 501(c)(3) | 2025 | $0 | $0 | 2025-12 |
| Infectious Disease Research and Teaching Institute of Houston | 501(c)(3) | 1983 | $0 | $0 | 2025-12 |
| Integral Wellbeing Foundation | 501(c)(3) | 2026 | | | |
| International Center for Applied Nu Rsing | 501(c)(3) | 2026 | | | |
| Invisible Signs Inc | 501(c)(3) | 2015 | $0 | $0 | 2024-12 |
| Iq Life Sciences Corporation | 501(c)(3) | 2025 | | $6.7 million | 2023-12 |
| Its in the Neighborhood Healthcare Solutions | 501(c)(3) | 2025 | $0 | $0 | 2024-12 |
| Jaa International Inc | 501(c)(3) | 2020 | $0 | $0 | 2025-12 |
| Jackson S Healthcare Providers Corporation | 501(c)(3) | 2025 | | | |
| Joseph Ncho Foundation Inc | 501(c)(3) | 2017 | $0 | $0 | 2024-12 |
| Joy and Peace Community Development Corporation | 501(c)(3) | 2012 | $0 | $0 | 2025-12 |
| Kidney Matters | 501(c)(3) | 2012 | $0 | $0 | 2025-12 |
| Killings Houston Health and Transportation Solution Inc | 501(c)(3) | 2021 | $0 | $0 | 2023-12 |
| Kindness Warriors | 501(c)(3) | 2019 | $0 | $0 | 2025-12 |
| Korean American Medical Association | 501(c)(3) | 2010 | $0 | $0 | 2025-12 |
| Kyssi Andrews Foundation for Pediatric Cancer | 501(c)(3) | 2019 | $0 | $0 | 2024-12 |
| La Leche League International Inc | 501(c)(3) | 2017 | $0 | $0 | 2026-03 |
| Learn To Play and Play To Learn Center of Houston | 501(c)(3) | 2022 | $0 | $0 | 2025-12 |
| Legacy Speaks Consulting | 501(c)(3) | 2025 | $0 | $0 | 2025-12 |
| Levare Womens Care | 501(c)(3) | 2024 | $0 | $0 | 2025-12 |
| Lifegift | 501(c)(3) | 2026 | | | |
| Lifegift Tissue Donation Services | 501(c)(3) | 2026 | | | |
| Love U Foundation Inc | 501(c)(3) | 2010 | $0 | $0 | 2025-12 |
| Loving Soles Inc | 501(c)(3) | 2015 | $0 | $0 | 2025-12 |
| MJS Legacy Foundation | 501(c)(3) | 2026 | | | |
| Margaret-Philomena Health Foundation | 501(c)(3) | 2022 | $0 | $0 | 2025-12 |
| Mary Joes Project | 501(c)(3) | 2021 | $0 | $0 | 2025-12 |
| Meat Your Future | 501(c)(3) | 2017 | | $1 | 2025-12 |
| Medcore Geriatric Assistance Program Inc | 501(c)(3) | 2017 | $0 | $0 | 2025-12 |
| Medcy Inc | 501(c)(3) | 2018 | $0 | $0 | 2025-12 |
| Medstar Global Foundation | 501(c)(3) | 2022 | $0 | $0 | 2024-12 |
| Memorial Hermann Information Exchange | 501(c)(3) | 2003 | $0 | $0 | 2025-06 |
| Menasa Group | 501(c)(3) | 2025 | $0 | $0 | 2025-12 |
| Menopause Matters Foundation | 501(c)(3) | 2015 | $0 | $0 | 2025-12 |
| Methodist Hospital | 501(c)(3) | 2010 | $0 | $156.4 million | 2024-12 |
| Methodist Hospital | 501(c)(3) | 2010 | | | |
| Methodist Hospital | 501(c)(3) | 2010 | | | |
| Methodist Hospital | 501(c)(3) | 2010 | | | |
| Methodist Hospital | 501(c)(3) | 2010 | | | |
| Methodist Hospital | 501(c)(3) | 2010 | | | |
| Methodist Hospital | 501(c)(3) | 2010 | | | |
| Methodist Hospital | 501(c)(3) | 2010 | | | |
| Methodist Hospital | 501(c)(3) | 2010 | | | 2024-12 |
| Methodist Hospital | 501(c)(3) | 2010 | | | 2003-12 |
| Methodist Hospital | 501(c)(3) | 2010 | | | |
| Methodist Hospital | 501(c)(3) | 2010 | | | 2003-12 |
| Methodist Hospital | 501(c)(3) | 2010 | | | |
| Methodist Hospital | 501(c)(3) | 2010 | | | 2001-12 |
| Methodist Hospital | 501(c)(3) | 2010 | | | |
| Methodist Hospital | 501(c)(3) | 2010 | $0 | $1 | 2020-12 |
| Methodist Hospital | 501(c)(3) | 2010 | | | |
| Methodist Hospital | 501(c)(3) | 2010 | | | |
| Miles Lifestyle Foundation Inc | 501(c)(3) | 2026 | | | |
| Military and Hospitaller Ord of St Lazarus of Jerusalem GRD Pri Am-Sw | 501(c)(10) | 1974 | $0 | $0 | 2025-12 |
| Minority Physicians Virtual Society | 501(c)(3) | 2016 | $0 | $0 | 2025-12 |
| Miss Utopia Organization | 501(c)(3) | 2024 | | | |
| Mom Global | 501(c)(3) | 2020 | $0 | $0 | 2023-12 |
| Monique Foundation Corporation | 501(c)(3) | 2024 | | | |
| Mothers Dialysis Care Inc | 501(c)(3) | 2020 | $0 | $0 | 2025-12 |
| Muellers Monster Mash - A Charitable Foundation LLC | 501(c)(3) | 2017 | $0 | $0 | 2025-12 |
| Nassau Stroke and Heart Foundation | 501(c)(3) | 2026 | | | |
| National Association of Muslim Charitable Clinics | 501(c)(3) | 2023 | | $6,500 | 2024-12 |
| National Dental Association Inc | 501(c)(3) | 2005 | $0 | $0 | 2025-12 |
| Neuron Community Foundation | 501(c)(3) | 2026 | | | |
| Nigerian Nurses Association Sugar Land | 501(c)(3) | 2025 | $0 | $0 | 2025-12 |
| Number 1 Apex Home Health Services | 501(c)(3) | 2026 | | | |
| Nurture Kare Resources Inc | 501(c)(3) | 2025 | | | |
| Ohaoma Progressive Union Inc | 501(c)(3) | 2013 | $0 | $0 | 2024-12 |
| One Love Support Foundation | 501(c)(3) | 2026 | | | |
| Opt2care | 501(c)(3) | 2025 | | | |
| Oral Care Matters Association | 501(c)(3) | 2025 | $0 | $0 | 2025-12 |
| Orthopedic Residency Improvement Fund LLC | 501(c)(3) | 2019 | | $54,453 | 2023-12 |
| Ostomy Association of the Houston Area | 501(c)(3) | 2005 | $0 | $0 | 2025-06 |
| Our Heroes Wear Capes | 501(c)(3) | 2026 | | | |
| PHC Global | 501(c)(3) | 2021 | | | |
| Parosee Inc | 501(c)(3) | 2024 | $0 | $0 | 2023-12 |
| Pathway Wound Alliance Inc | 501(c)(3) | 2025 | | | |
| Pathways for Life Foundation | 501(c)(3) | 2026 | $0 | $0 | 2025-12 |
| Patient Discharge Initiative | 501(c)(3) | 2026 | | | |
| Philippine Nurses Association of Metropolitan Houston FNDTN Inc | 501(c)(3) | 2009 | $0 | $0 | 2025-12 |
| Physicians for Palestine | 501(c)(3) | 2025 | | $281,005 | 2024-12 |
| Pinkbreastiesista | 501(c)(3) | 2026 | | | |
| Podhigai Foundation | 501(c)(3) | 2025 | | $10,000 | 2024-12 |
| Positive Match Inc | 501(c)(3) | 2024 | $0 | $0 | 2024-10 |
| Pregnant and Black Inc | 501(c)(3) | 2025 | $0 | $0 | 2025-12 |
| Premonation Organization | 501(c)(3) | 2025 | | $240,000 | 2019-12 |
| Prepared Places Inc | 501(c)(3) | 2014 | | $26,563 | 2025-06 |
| Pretty Girls With Cancer | 501(c)(3) | 2020 | $0 | $0 | 2025-12 |
| Progress Arts Group Inc | 501(c)(3) | 2005 | $0 | $0 | 2024-12 |
| Project Healthy Neighbors | 501(c)(3) | 2024 | $0 | $0 | 2025-12 |
| Purple Fortitude Foundation | 501(c)(3) | 2024 | $0 | $0 | 2025-12 |
| Rehab Your Life | 501(c)(3) | 2020 | $0 | $0 | 2023-12 |
| Reimagination Engine | 501(c)(3) | 2020 | $0 | $0 | 2025-12 |
| Resource Foundation | 501(c)(3) | 2012 | $0 | $0 | 2025-12 |
| Richa Memorial Fund Inc | 501(c)(3) | 2017 | $0 | $0 | 2025-12 |
| Robins Haven of Hope Inc | 501(c)(3) | 2012 | $0 | $0 | 2025-12 |
| Roc Center | 501(c)(3) | 2026 | | | |
| Ruby Ball Foundation | 501(c)(3) | 2021 | $0 | $0 | 2025-12 |
| SSW Stroke Association | 501(c)(3) | 2024 | | | |
| Salte and Soul Wellness | 501(c)(3) | 2026 | | | |
| Samir Becic Foundation | 501(c)(3) | 2015 | $0 | $0 | 2024-12 |
| Santo Clinic | 501(c)(3) | 2013 | $0 | $0 | 2024-12 |
| Sarcoma Patient Assistance Group | 501(c)(3) | 2018 | | $21,290 | 2025-04 |
| Sarwar Shahida Research Institute O F Cardiovascular Science Trust-Us | 501(c)(3) | 2026 | | | |
| Save Our Crown Inc | 501(c)(3) | 2023 | $0 | $0 | 2025-12 |
| Sba Health Ministry | 501(c)(3) | 2024 | $0 | $0 | 2026-07 |
| School of Nursing Aba Alumni Association | 501(c)(3) | 2020 | $0 | $0 | 2024-12 |
| Selah Clinic and Community Center Inc | 501(c)(3) | 2024 | $0 | $0 | 2025-12 |
| Shinyanga Health Aide and Medical Assistance Inc | 501(c)(3) | 2002 | | $1 | 2024-12 |
| Sikh Family Life | 501(c)(3) | 2017 | $0 | $0 | 2026-06 |
| Sisters of Charity of the Incarnate Word | 501(c)(3) | 1946 | | | 1999-06 |
| Smith-Whigham Center | 501(c)(3) | 2022 | $0 | $0 | 2025-12 |
| Southeast Texas Family Planning and Cancer Screening | 501(c)(3) | 1986 | $0 | $0 | 2025-12 |
| Southern Giving Foundation | 501(c)(3) | 2025 | $0 | $0 | 2025-12 |
| Southstar Outreach Non Profit Corp | 501(c)(3) | 2019 | | $1 | 2024-12 |
| Stews Dialysis and Transplant Infor Mation and Support Group Inc | 501(c)(3) | 2026 | | | |
| Stronger Than the Bullet Foundation | 501(c)(3) | 2025 | | | |
| Student Health Services at Academicmedical Centers | 501(c)(3) | 2008 | $0 | $0 | 2025-12 |
| Students for Medical Aid Relief and Treatment | 501(c)(3) | 2021 | $0 | $0 | 2024-12 |
| TH Foundation | 501(c)(3) | 2024 | $0 | $0 | 2025-12 |
| TMC Medical Associates | 501(c)(3) | 2026 | $0 | $1 | 2025-12 |
| TTMC Foundation | 501(c)(3) | 2025 | | | |
| Tara Sansthan | 501(c)(3) | 2017 | $0 | $0 | 2024-12 |
| Tareeq Alzuhoor Charity Inc | 501(c)(3) | 2023 | $0 | $0 | 2025-12 |
| Temple Build Initiative | 501(c)(3) | 2025 | $0 | $0 | 2025-12 |
| Texas Gulf Coast Association for Healthcare Quality | 501(c)(3) | 1994 | $0 | $0 | 2025-12 |
| Texas Gulf Coast CHW Promotores Association | 501(c)(3) | 2016 | $0 | $0 | 2025-12 |
| Texas Nannna Inc | 501(c)(3) | 2019 | $0 | $0 | 2025-12 |
| Texas-Gulfcoast Society for | 501(c)(3) | 1988 | $0 | $0 | 2026-03 |
| The Coding Initiative | 501(c)(3) | 2023 | $0 | $0 | 2024-12 |
| The Good Life Meca Project | 501(c)(3) | 2025 | $0 | $0 | 2025-05 |
| The Hourclinic | 501(c)(3) | 2010 | $0 | $0 | 2024-12 |
| The Lone Star Veterans Health Initi Ative | 501(c)(3) | 2025 | | | |
| The Mattern Foundation | 501(c)(3) | 2026 | | | |
| Therapeutic Massage for Seniors | 501(c)(3) | 2024 | $0 | $0 | 2024-12 |
| Timothy Ebie Rural Empowerment Foundation - Teref- Inc | 501(c)(3) | 2016 | $0 | $0 | 2025-12 |
| Tops Club Inc | 501(c)(3) | 2008 | $0 | $0 | 2026-03 |
| Tops Club Inc | 501(c)(3) | 2008 | $0 | $0 | 2026-03 |
| Tops Club Inc | 501(c)(3) | 2008 | $0 | $0 | 2026-03 |
| Towes | 501(c)(3) | 2016 | $0 | $0 | 2024-12 |
| Tribe Consulting P&R | 501(c)(3) | 2025 | | | |
| Ujima Health Connection | 501(c)(3) | 2009 | $0 | $0 | 2025-12 |
| United Veterans Health Centers Inc | 501(c)(3) | 2023 | $0 | $0 | 2025-12 |
| United2cure Children Foundation | 501(c)(3) | 2013 | $0 | $0 | 2025-12 |
| University of Houston Community Corporation | 501(c)(3) | 2024 | $0 | $0 | 2023-08 |
| Usleep America | 501(c)(3) | 2024 | | | |
| Vals Helping Hands | 501(c)(3) | 2025 | $0 | $0 | 2024-12 |
| Vietnamese American Advanced Practi Ce Providers Association | 501(c)(3) | 2025 | | | |
| Wellness Above Borders & Beyond | 501(c)(3) | 2020 | $0 | $0 | 2025-12 |
| Willard R Cooke Obstetrical & Gynecological Society Inc | 501(c)(3) | 2017 | $0 | $0 | 2025-08 |
| Win All Else Fails | 501(c)(3) | 2024 | $0 | $0 | 2025-12 |
| Wings of Hope TX LLC | 501(c)(3) | 2019 | $0 | $0 | 2024-12 |
| Your Health First Education Inc | 501(c)(3) | 2016 | $0 | $0 | 2024-12 |
| Youth4seniors Foundation | 501(c)(3) | 2025 | $0 | $0 | 2025-12 |
| Texas Medical Center Venture Fund | 501(c)(3) | 2018 | $-10,682 | $49.8 million | 2024-12 |