| Lancaster County Community Foundation | 501(c)(3) | 2004 | $24 million | $184.6 million | 2024-12 |
| Eden Bridge Foundation | 501(c)(3) | 2004 | $7.9 million | $22.5 million | 2025-06 |
| Homes for Hope | 501(c)(3) | 2008 | $3.7 million | $4.6 million | 2025-12 |
| Lancaster General Health Foundation | 501(c)(3) | 2009 | $3.6 million | $2.7 million | 2025-06 |
| The Children Deserve A Chance Foundation | 501(c)(3) | 2009 | $2.3 million | $1.4 million | 2025-06 |
| Community Basics Inc | 501(c)(3) | 1998 | $2.3 million | $10.5 million | 2024-12 |
| Non-Profit Management Solutions | 501(c)(3) | 2014 | $1.7 million | $10.6 million | 2025-06 |
| LMC Legacy Foundation | 501(c)(3) | 2017 | $667,408 | $10.3 million | 2025-06 |
| Aspire Foundation for Excentia Human Services | 501(c)(3) | 2023 | $658,243 | $563,217 | 2025-06 |
| Clarence Schock Scholarship & Fellowship Charitable Trust I | 501(c)(3) | 2015 | $358,801 | $6.8 million | 2024-10 |
| Saint John Paul II Legacy Foundation Inc | 501(c)(3) | 2024 | $185,976 | $112,004 | 2024-12 |
| Touchstone Foundation | 501(c)(3) | 1989 | $124,491 | $512,806 | 2024-12 |
| Clarence Schock Memorial Park at Governor Dick Trust | 501(c)(3) | 2015 | $60,118 | $1.1 million | 2024-12 |
| S June Smith Center Foundation Inc | 501(c)(3) | 1994 | $55,428 | $343,714 | 2025-06 |
| Saltbox House | 501(c)(3) | 2016 | $35,962 | $195,206 | 2025-12 |
| 5 Days in July | 501(c)(3) | 2025 | $0 | $0 | 2025-12 |
| Abigail L Longenecker Memorial Foundation | 501(c)(3) | 1998 | | $209,581 | 2025-12 |
| Aimee Y Decker Charitable Trust | 501(c)(3) | 1995 | | $707,579 | 2025-05 |
| Ammon & Dorothy Patrick T A | 501(c)(3) | 2002 | | $394,588 | 2025-07 |
| Anne Brossman Sweigart Charitable Foundation | 501(c)(3) | 2006 | | $8.2 million | 2024-12 |
| Arnold Family Foundation | 501(c)(3) | 2005 | | $1.3 million | 2025-06 |
| Arnold Foundation | 501(c)(3) | 2016 | | $2.2 million | 2025-12 |
| Arthur M Peters Family Scholarship Fund 47F108014 | 501(c)(3) | 2018 | | $847,423 | 2024-12 |
| Ashbrook D Snelbaker Tuw 47wo64010 | 501(c)(3) | 2006 | | $3.1 million | 2026-03 |
| Bensons Dream Co | 501(c)(3) | 2025 | $0 | $0 | 2024-12 |
| Breidegam Family Foundation Inc | 501(c)(3) | 2001 | | $45.2 million | 2025-12 |
| C & E Schock Trust Uw Fbo Presbyterian Homes of Central Penna | 501(c)(3) | 2019 | | $1.8 million | 2024-12 |
| Carl E & Leah Hoffmaster Mem Trust 47F088018 | 501(c)(3) | 2003 | | $185,414 | 2025-09 |
| Charlies Wings of Hope | 501(c)(3) | 2025 | $0 | $0 | 2024-12 |
| Chester & Gail Cunningham Memorial Fund | 501(c)(3) | 2004 | | $123,362 | 2024-12 |
| Circle of Hope Foundation | 501(c)(3) | 2022 | | $10,214 | 2023-12 |
| City Limits Foundation | 501(c)(3) | 2023 | | $6.5 million | 2025-12 |
| Clark Assoc Charitable FDN | 501(c)(3) | 2001 | | $51.3 million | 2024-12 |
| Cleveland Family Foundation | 501(c)(3) | 2006 | | $3 million | 2025-12 |
| Clyde E & Zada V Peters Charitable Trust 6313500 | 501(c)(3) | 1997 | | $376,210 | 2025-06 |
| Cramer Family Foundation PC Trust | 501(c)(3) | 2009 | | $1.9 million | 2025-06 |
| Crestwood Foundation | 501(c)(3) | 2015 | | $265,203 | 2025-12 |
| D B Anderson Charitable Foundation | 501(c)(3) | 2009 | | $3.4 million | 2025-12 |
| Decent Life Volunteer | 501(c)(3) | 2011 | $0 | $0 | 2024-12 |
| Deerin Foundation | 501(c)(3) | 2017 | | $1 | 2025-12 |
| Disciples Worldwide Foundation | 501(c)(3) | 2025 | | $751,195 | 2024-12 |
| Dodge Family Foundation | 501(c)(3) | 2008 | | $2.5 million | 2025-12 |
| Dollena K Drane T-W Geneva College Trust | 501(c)(3) | 2004 | | $1.1 million | 2026-03 |
| Dream Away Foundation | 501(c)(3) | 2023 | | $611,955 | 2025-12 |
| Dunlap-Stohler Charitable Trust | 501(c)(3) | 2011 | | $2.6 million | 2025-12 |
| E & M Williams Trust Ua Fbo Hospice | 501(c)(3) | 2005 | | $529,366 | 2026-04 |
| E Ann Klein Charitable Trust | 501(c)(3) | 2009 | | $2.8 million | 2023-10 |
| Earl & Esther Glatfelter Memorial 46F023017 | 501(c)(3) | 2004 | | $169,090 | 2025-12 |
| Edward Froelich Charitable Trust Uw 47F001011 | 501(c)(3) | 2006 | | $5.9 million | 2023-12 |
| Edward S Spangler Memorial Trust Ua | 501(c)(3) | 2004 | | $51,647 | 2025-12 |
| Faithful Journey Foundation | 501(c)(3) | 2022 | | | 2024-12 |
| Ferree Foundation | 501(c)(3) | 2004 | | $21.8 million | 2024-12 |
| Francis R Gelnett Irrv Trust | 501(c)(3) | 2019 | | $5.3 million | 2024-12 |
| Fryer Family Foundation | 501(c)(3) | 2022 | | $1 | 2025-12 |
| Fulton Forward Foundation | 501(c)(3) | 2022 | | $7.9 million | 2024-12 |
| George F Coffin Jr and Claire E Coffin Trust | 501(c)(3) | 2008 | | $2.6 million | 2025-12 |
| George and Cindy Rusu Family Foundation | 501(c)(3) | 2011 | | $11.6 million | 2024-12 |
| Ginko Foundation | 501(c)(3) | 2007 | | $770,356 | 2024-12 |
| Global Christian Organizations and Development | 501(c)(3) | 2014 | $0 | $0 | 2025-12 |
| Gustav and Irene Uhlig Charitable Trust Fbo United Way of Lebanon | 501(c)(3) | 2007 | | $1.1 million | 2025-10 |
| H Kathryn Hoover Trust Uw | 501(c)(3) | 2004 | | $830,060 | 2025-12 |
| H M Levitz Memorial Park Charitable Trust Ua | 501(c)(3) | 1997 | | $189,826 | 2025-08 |
| Haverstick Family Trust | 501(c)(3) | 2006 | | $840,852 | 2025-12 |
| Heller Family Foundation | 501(c)(3) | 2022 | | $623 | 2023-12 |
| Henry P and Mary B Stager Memorial Nursing Scholarship | 501(c)(3) | 1995 | | $1.3 million | 2024-10 |
| Herbert W and Maria Anna Wanner Foundation | 501(c)(3) | 2011 | | $260,557 | 2025-12 |
| High Foundation | 501(c)(3) | 2019 | | $307.3 million | 2025-06 |
| Hilda C Krause Interv Trust Fbo Hilda Krause 08-04-80 | 501(c)(3) | 2020 | | $483,426 | 2025-12 |
| Hoffman Family Foundation of Hanover | 501(c)(3) | 2008 | | $826,150 | 2025-06 |
| Horst Foundation | 501(c)(3) | 2000 | | $8 million | 2025-12 |
| Hortulani Foundation | 501(c)(3) | 2017 | | $261,264 | 2025-12 |
| Integrative Manual Therapy Donor Trust | 501(c)(3) | 2020 | | $4,963 | 2025-12 |
| Irene Mae Wright Charitable Trust | 501(c)(3) | 1995 | | $402,761 | 2025-12 |
| J Clifford & Ruth M Kopp Charitable Trust | 501(c)(3) | 1998 | | $2.9 million | 2024-10 |
| J R Hersey Tuw Boys & Girls Club | 501(c)(3) | 2002 | | $4 million | 2025-11 |
| J Robert Odonnell Irrv Trust B 43V115010 | 501(c)(3) | 2011 | | $477,200 | 2025-12 |
| Jacob Peacock TW Luther Acres | 501(c)(3) | 2007 | | $1.2 million | 2025-12 |
| Jacob R Hershey Irrv Trust TW Charities | 501(c)(3) | 2001 | | $1.9 million | 2024-11 |
| James R Vial Trust Under Will | 501(c)(3) | 2019 | | $746,463 | 2025-12 |
| James W Curry Trust Ua | 501(c)(3) | 2004 | | $1.5 million | 2024-12 |
| Jewish Family Service | 501(c)(3) | 1998 | $0 | $0 | 2025-12 |
| John & Jeanette Witmer Ta Charities Trust | 501(c)(3) | 2006 | | $711,502 | 2024-08 |
| John C Barnhart Endow Fund Mt Pleasant Umc 41V287011 | 501(c)(3) | 2016 | | $222,965 | 2025-06 |
| John Campion Trust Fbo Our Lady of Refuge Perpetual Care Fund | 501(c)(3) | 2015 | | $115,189 | 2025-07 |
| Julia B Moran Trust Uw | 501(c)(3) | 1998 | | $364,979 | 2024-12 |
| K O Spessard Trust 2 31V028010 | 501(c)(3) | 2008 | | $95,255 | 2025-12 |
| K6 Family Foundation | 501(c)(3) | 2022 | | $545,308 | 2025-12 |
| Kindness Grows | 501(c)(3) | 2024 | $0 | $0 | 2025-12 |
| Kirchhoff Family Foundation | 501(c)(3) | 2013 | | $3.4 million | 2025-12 |
| Kopp Charitable Trust Fbo Cornwall Umc | 501(c)(3) | 2021 | | $252,522 | 2025-12 |
| Lynn W & Timothy W Peters Family Foundation | 501(c)(3) | 2000 | | $178,977 | 2025-12 |
| Mae Wike Spitler Trust | 501(c)(3) | 2004 | | $485,415 | 2025-12 |
| Marie Ambrose Levitz Scholarship Fund | 501(c)(3) | 2001 | | $58,040 | 2024-08 |
| Marino Family Foundation Inc | 501(c)(3) | 2006 | | $300,345 | 2025-12 |
| Mary A Roche Tuw 1 Charities | 501(c)(3) | 2004 | | $152,856 | 2024-12 |
| Mary C Melson TW Henry G Long Home 47F004015 | 501(c)(3) | 2006 | | $279,958 | 2025-12 |
| Metzler Family Foundation | 501(c)(3) | 2006 | | $2 million | 2024-12 |
| Neal G Yiengst Scholarship Fund Trust | 501(c)(3) | 2002 | | $1 | 2025-12 |
| Nettie S Weiser Trust Uw No 172 | 501(c)(3) | 2004 | | $245,574 | 2025-12 |
| Next Generation Foundation | 501(c)(3) | 2005 | | $2.9 million | 2025-12 |
| Norstar Foundation | 501(c)(3) | 2001 | $0 | $0 | 2024-12 |
| Paul J Kohr & Arlene M Kohr Mem Trust | 501(c)(3) | 2019 | | $1.5 million | 2026-03 |
| Pauline Anderson Hess and Norman C Hess Charitable Trust | 501(c)(3) | 2009 | | $3.2 million | 2024-12 |
| Peter Horst Trust Uw Fbo Historic Schaefferstown | 501(c)(3) | 2000 | | $345,301 | 2025-10 |
| Rettew Charitable Foundation | 501(c)(3) | 2012 | | $39,976 | 2025-12 |
| Richard S & Ann B Barshinger Family Foundation | 501(c)(3) | 2013 | | $12.6 million | 2024-12 |
| Riggs-Conard Trust Fund | 501(c)(3) | 1999 | | $383,915 | 2024-11 |
| Rise Up Abbahar | 501(c)(3) | 2023 | $0 | $0 | 2024-12 |
| Robert H & Beverly U Fowler Foundation | 501(c)(3) | 1999 | | $862,941 | 2025-12 |
| Russell Shertzer Trust Uw Fbo Frey Village | 501(c)(3) | 2004 | | $891,105 | 2025-12 |
| Ruth E Boyer Charitable Trust Uw | 501(c)(3) | 2004 | | $82,407 | 2025-06 |
| S Catherine Kachel Tuw Wakefield Bible 47F049010 | 501(c)(3) | 2006 | | $215,485 | 2025-12 |
| Sallie E Lauser Trust Fbo St Pauls United Church of Christ 33V004 | 501(c)(3) | 2004 | | $373,802 | 2025-12 |
| Seraph Foundation | 501(c)(3) | 1997 | | $155,034 | 2025-06 |
| Stager Charitable Trust Fbo Hospitals 47F009014 | 501(c)(3) | 1998 | | $867,873 | 2024-08 |
| Stager Charitable Trust Fbo Zion | 501(c)(3) | 1997 | | $732,325 | 2024-08 |
| Stillman Family Charitable Foundation | 501(c)(3) | 2023 | | $6,923 | 2025-12 |
| Tecumseh Milestone Foundation | 501(c)(3) | 2002 | | $1 million | 2025-10 |
| Tenthirty Foundation | 501(c)(3) | 2026 | | | |
| The Gabriel Foundation | 501(c)(3) | 2009 | | $342,031 | 2025-12 |
| The Kindness Coalition | 501(c)(3) | 2015 | | $530,061 | 2025-12 |
| The Royer Family Charitable Foundation | 501(c)(3) | 2009 | | $7 million | 2025-12 |
| The Susan Sarandon Charitable Foundation | 501(c)(3) | 2003 | | $3.6 million | 2025-12 |
| The William S Rothermel Foundation | 501(c)(3) | 2007 | | $212,864 | 2024-12 |
| The@kalas Foundation | 501(c)(3) | 2009 | | $2.6 million | 2025-12 |
| Thomas A and Georgina T Russofoundation | 501(c)(3) | 2007 | | $15.6 million | 2024-12 |
| Vessel of Honor Family Foundation | 501(c)(3) | 2024 | | | |
| WM and Marion French Scholarship Fund | 501(c)(3) | 1999 | | $294,039 | 2025-05 |
| Weiler Family Foundation Inc | 501(c)(3) | 1998 | | $9.8 million | 2025-12 |
| William J Ditto Truw | 501(c)(3) | 2019 | | $834,071 | 2025-12 |
| Wirth It Foundation | 501(c)(3) | 2026 | | | |
| Wolgemuth Irrv Trust Uw Fbo West Green Tree Church | 501(c)(3) | 2003 | | $278,360 | 2025-07 |
| Yesarelah Ministries Inc | 501(c)(3) | 1993 | $0 | $0 | 2024-12 |