| University at Buffalo Foundation Inc | 501(c)(3) | 1963 | $128.7 million | $1.55 billion | 2025-06 |
| Canisius University of Buffalo New York | 501(c)(3) | 1971 | $110.7 million | $284.4 million | 2025-05 |
| Dyouville College | 501(c)(3) | 1943 | $99.5 million | $259.1 million | 2025-05 |
| Faculty Students Association of State University of New York | 501(c)(3) | 1966 | $53.7 million | $61.9 million | 2025-05 |
| Charter School for Applied Technologies | 501(c)(3) | 2002 | $42.9 million | $62.9 million | 2025-06 |
| University at Buffalo Surgeons Inc | 501(c)(3) | 2003 | $39.5 million | $28.4 million | 2025-12 |
| Ubf Faculty-Student Housing Corp | 501(c)(3) | 1990 | $29.5 million | $148.2 million | 2025-06 |
| Buffalo Academy of Science Charter School | 501(c)(3) | 2004 | $26 million | $56.5 million | 2025-06 |
| Nichols School of Buffalo | 501(c)(3) | 1950 | $25.7 million | $115.4 million | 2025-06 |
| Tapestry Charter School | 501(c)(3) | 2002 | $21 million | $41.5 million | 2025-06 |
| Trocaire College | 501(c)(3) | | $20.1 million | $51.7 million | 2025-05 |
| Say Yes Buffalo Scholarship Inc | 501(c)(3) | 2015 | $18.1 million | $61.1 million | 2025-06 |
| Global Concepts Charter School | 501(c)(3) | 2002 | $15.9 million | $26.5 million | 2025-06 |
| South Buffalo Charter School | 501(c)(3) | 2001 | $15.9 million | $40.3 million | 2025-06 |
| Reach Academy Charter School | 501(c)(3) | 2017 | $15.5 million | $21.6 million | 2025-06 |
| Elmwood Village Charter School 2 | 501(c)(3) | 2017 | $14.3 million | $20.2 million | 2025-06 |
| Buffalo & Erie County Public Library | 501(c)(3) | 1996 | $13.8 million | $4.2 million | 2024-12 |
| Ub Associates Inc | 501(c)(3) | 2000 | $12.4 million | $58.2 million | 2025-12 |
| Buffalo State College Foundation Inc | 501(c)(3) | 1966 | $12.1 million | $127 million | 2025-06 |
| Elmwood Franklin School Inc | 501(c)(3) | 1948 | $11 million | $21 million | 2025-06 |
| University Urology Inc | 501(c)(3) | 2001 | $9.4 million | $325,950 | 2025-12 |
| Buffalo United Charter School | 501(c)(3) | 2004 | $9 million | $668,666 | 2025-06 |
| West Buffalo Charter School | 501(c)(3) | 2011 | $8.5 million | $15.5 million | 2025-06 |
| Health Sciences Charter School | 501(c)(3) | 2009 | $8.3 million | $11 million | 2025-06 |
| Buffalo Seminary | 501(c)(3) | 1935 | $8.2 million | $19.5 million | 2025-06 |
| Western New York Maritime Charter School | 501(c)(3) | 2004 | $7.3 million | $6.6 million | 2025-06 |
| Holy Cross Head Start Inc | 501(c)(3) | 1986 | $7.3 million | $1.7 million | 2025-02 |
| Enterprise Charter School | 501(c)(3) | 2004 | $6.8 million | $11.5 million | 2025-06 |
| Westminster Community Charter School | 501(c)(3) | 2005 | $6.8 million | $12.3 million | 2025-06 |
| King Center Charter School | 501(c)(3) | 2000 | $6.5 million | $7.2 million | 2025-06 |
| Buffalo State College Foundation Housing Corporation | 501(c)(3) | 2009 | $6.1 million | $36.2 million | 2025-06 |
| Charter School of Inquiry | 501(c)(3) | 2015 | $5.1 million | $4.9 million | 2025-06 |
| University at Buffalo Otolaryngology Inc | 501(c)(3) | 2004 | $5 million | $1.5 million | 2025-12 |
| Specialized Early Childhood Center of Western New York Inc | 501(c)(3) | 1987 | $4.8 million | $3.3 million | 2025-06 |
| University at Buffalo Student Association Inc | 501(c)(3) | 2019 | $4.4 million | $5.8 million | 2025-07 |
| Primary Hall Preparatory Charter School | 501(c)(3) | 2020 | $3.4 million | $2.7 million | 2025-06 |
| Hearts Foundation Inc | 501(c)(3) | 2001 | $3.2 million | $4.4 million | 2024-12 |
| Wned Foundation Inc | 501(c)(3) | 2002 | $3.1 million | $29.9 million | 2025-06 |
| Buffalo Creek Academy Inc | 501(c)(3) | 2020 | $3.1 million | $5.8 million | 2024-06 |
| Brass Foundation Incorporated | 501(c)(3) | 2022 | $2.6 million | $41.3 million | 2025-06 |
| Ub Oral & Maxillofacial Surgery Inc | 501(c)(3) | 2011 | $2.5 million | $1.2 million | 2025-12 |
| Epic-Every Person Influences Children Inc | 501(c)(3) | 1982 | $2.4 million | $1.5 million | 2025-12 |
| Green Options Buffalo | 501(c)(3) | 2011 | $2.2 million | $989,477 | 2025-12 |
| Education Collaborative of Wny Inc | 501(c)(3) | 2000 | $1.9 million | $632,681 | 2025-06 |
| Buffalo Commons Charter School | 501(c)(3) | 2021 | $1.7 million | $625,385 | 2025-06 |
| Universal School | 501(c)(3) | 2003 | $1.6 million | $537,439 | 2025-06 |
| Brick Buffalo Academy | 501(c)(3) | 2023 | $1.6 million | $1.5 million | 2025-06 |
| University at Buffalo Graduate Student Association Inc | 501(c)(3) | 2021 | $1.6 million | $4.6 million | 2025-07 |
| Computers for Children Inc | 501(c)(3) | 1998 | $1.4 million | $893,782 | 2024-12 |
| Huron University College Foundation USA | 501(c)(3) | 2010 | $1.3 million | $1,758 | 2025-12 |
| Ridley College Fund USA Inc | 501(c)(3) | 1964 | $1.1 million | $8.3 million | 2026-06 |
| Dart Collective Inc | 501(c)(3) | 2023 | $1.1 million | $872,384 | 2024-12 |
| Read To Succeed Buffalo Inc | 501(c)(3) | 2009 | $1.1 million | $958,253 | 2025-12 |
| Erie Community College Foundation Inc | 501(c)(3) | 1988 | $974,063 | $8.2 million | 2025-08 |
| Buffalo Go Green Inc | 501(c)(3) | 2015 | $943,162 | $3.9 million | 2024-12 |
| United Students Government Service Group Inc | 501(c)(3) | 1976 | $900,737 | $885,082 | 2025-05 |
| Mount St Marys Child Care Center Inc | 501(c)(3) | 1998 | $865,703 | $818,000 | 2024-12 |
| F Bites Inc | 501(c)(3) | 2016 | $662,287 | $342,559 | 2024-12 |
| Almustaqbal Foundation | 501(c)(3) | 2013 | $621,955 | $593,384 | 2025-07 |
| University at Buffalo Foundation Incubator Inc | 501(c)(3) | 1987 | $588,111 | $1.2 million | 2025-06 |
| University at Buffalo Medical Student Polity Inc | 501(c)(3) | 2021 | $420,275 | $426,095 | 2025-07 |
| Ub Alumni Association Inc | 501(c)(3) | 1999 | $370,809 | $1.6 million | 2025-06 |
| Enlightenment Bookstore and Literary Arts Center Inc | 501(c)(3) | 2003 | $366,833 | $165,291 | 2025-12 |
| Foundation for Deaf Education | 501(c)(3) | 1997 | $338,654 | $1.2 million | 2025-06 |
| Endeavor Western New York | 501(c)(3) | 2020 | $282,000 | $52,010 | 2024-12 |
| Buffalo Sports Wellness Association Inc | 501(c)(3) | 2009 | $280,545 | $183,968 | 2025-12 |
| First Hand Learning Inc | 501(c)(3) | 1999 | $277,462 | $223,389 | 2025-12 |
| Accessible Academics USA Inc | 501(c)(3) | 2016 | $227,776 | $63,606 | 2025-06 |
| Cazenovia Community Resource Center Inc | 501(c)(3) | 2009 | $224,119 | $353,118 | 2025-12 |
| Lpe Collective Inc | 501(c)(3) | 2018 | $207,058 | $154,960 | 2025-12 |
| University at Buffalo Student Bar Association Inc | 501(c)(3) | 2021 | $187,968 | $202,710 | 2025-07 |
| University at Buffalo Dental Student Association Inc | 501(c)(3) | 2020 | $186,212 | $213,864 | 2025-07 |
| Galactic Tribe Inc | 501(c)(3) | 2021 | $168,058 | $42,926 | 2024-12 |
| Committee for the Buffalo Religious Arts Center Inc | 501(c)(3) | 2008 | $157,697 | $618,522 | 2024-12 |
| Educators of America Inc | 501(c)(3) | 2015 | $147,416 | $25,225 | 2024-12 |
| City Honors Foundation | 501(c)(3) | 1997 | $147,292 | $300,196 | 2025-06 |
| University Dental Practice Services Inc | 501(c)(3) | 1999 | $125,704 | $328,340 | 2025-12 |
| University at Buffalo Pharmacy Student Association Inc | 501(c)(3) | 2021 | $118,496 | $193,688 | 2025-07 |
| Shannon School for Girls | 501(c)(3) | 1977 | $114,584 | $1.1 million | 2025-05 |
| Friends of Buffalo Creek Inc | 501(c)(3) | 2021 | $111,553 | $28,388 | 2025-06 |
| North Tonawanda Athletic Association | 501(c)(3) | 2020 | $110,896 | $22,677 | 2024-12 |
| Faculty Student Association of State University College at Buffal | 501(c)(3) | 1964 | $99,506 | $1.6 million | 2026-06 |
| Proj Learn Achieve & Responsibility for Inner-City Students | 501(c)(3) | 2006 | $95,000 | $2,159 | 2025-08 |
| Alumni Association of State University College at Buffalo | 501(c)(3) | 1962 | $93,791 | $756,123 | 2025-06 |
| Library Foundation of Buffalo and Erie County Inc | 501(c)(3) | 1992 | $92,334 | $3.3 million | 2025-03 |
| Bennett Alumni Association Inc | 501(c)(3) | 2019 | $89,480 | $240,906 | 2025-05 |
| Bits and Bytes Stem Foundation Inc | 501(c)(3) | 2024 | $86,285 | $16,433 | 2025-12 |
| Western New York Minority Media Professionals | 501(c)(3) | 2000 | $78,370 | $135,717 | 2024-12 |
| Orchard Park Parent-Teachers Organization Inc | 501(c)(3) | 1981 | $77,946 | $55,605 | 2025-06 |
| Rise of Wny Inc | 501(c)(3) | 2023 | $76,128 | $63,491 | 2025-12 |
| Sigma Delta Tau Society | 501(c)(7) | 1948 | $64,155 | $3,110 | 2025-06 |
| State University of New York Career Development Organization Inc | 501(c)(4) | 2014 | $58,175 | $53,959 | 2026-06 |
| Spectrum Student Periodical Inc | 501(c)(3) | 1974 | $56,622 | $78,344 | 2025-07 |
| North American Catalan Society Inc | 501(c)(3) | 2017 | $35,232 | $87,147 | 2025-06 |
| Proctor R Tuw Fbo School District | 501(c)(3) | 2019 | $30,884 | $677,081 | 2025-07 |
| South Park High School Alumni Association Incorporated | 501(c)(3) | 2022 | $30,650 | $47,627 | 2024-12 |
| University at Buffalo Graduate Management Student Association Inc | 501(c)(3) | 2021 | $28,404 | $13,156 | 2025-07 |
| Celaaub Inc | 501(c)(3) | 1999 | $19,076 | $43,028 | 2023-06 |
| H Sherman Fbo Lyndon State College | 501(c)(3) | 2019 | $18,673 | $167,517 | 2025-12 |
| Wny Education Alliance Inc | 501(c)(3) | 2023 | $18,370 | $1,093 | 2024-12 |
| Oracle Building Corporation | 501(c)(3) | 2010 | $16,439 | $817,800 | 2025-06 |
| Men Allied for the Need To Understand Prostate Cancer Manup I | 501(c)(3) | 2018 | $11,673 | $6,269 | 2024-12 |
| Center for Family Systems Theory of Western New York Inc | 501(c)(3) | 2005 | $8,321 | $134,904 | 2025-06 |
| Foundation for the Toronto Public Library | 501(c)(3) | 2004 | $5,832 | $14,526 | 2025-12 |
| Institute for Health Care Ethics Inc | 501(c)(3) | 2023 | $5,300 | $2,516 | 2025-12 |
| Ras Scholarship Fund Inc | 501(c)(3) | 2011 | $1,474 | $44,182 | 2025-12 |
| Olmsted School Foundation | 501(c)(3) | 2009 | $482 | $77,697 | 2023-06 |
| 1964 Scholarship | 501(c)(3) | 2018 | $0 | $0 | 2026-06 |
| A Claire Gaskins Harper Scholarship Endowment | 501(c)(3) | 1999 | | $848,148 | 2025-12 |
| Afro American Police Assoc | 501(c)(3) | 1991 | $0 | $0 | 2025-12 |
| After School Association Inc | 501(c)(3) | 1997 | | | |
| Alpha Sigma Phi Fraternity Inc | 501(c)(7) | 1941 | $0 | $0 | 2025-06 |
| Architect for Kids Inc | 501(c)(3) | 2024 | $0 | $0 | 2025-04 |
| Aspiring Scientists Coalition | 501(c)(3) | 2026 | $0 | $0 | 2025-12 |
| Ausome Care Foundation | 501(c)(3) | 2026 | | | |
| BSCR Corporation | 501(c)(3) | 2001 | $0 | $2,958 | 2025-06 |
| Bella & Aces | 501(c)(3) | 2023 | | $1 | 2025-12 |
| Brighter Future Education Network | 501(c)(3) | 2020 | $0 | $0 | 2023-07 |
| Buffalo 2020 Development Corporation | 501(c)(3) | 2011 | | $7.6 million | 2025-06 |
| Buffalo Association of Black Journalist Inc | 501(c)(3) | 2000 | $0 | $0 | 2025-12 |
| Buffalo Bangladeshi Sports Association Inc | 501(c)(3) | 2022 | $0 | $0 | 2025-12 |
| Buffalo Coalition Against Antisemit Ism Inc | 501(c)(3) | 2025 | | | |
| Buffalo Montessori Teachers Ed Prog | 501(c)(3) | 2002 | $0 | $0 | 2025-08 |
| Buffalo Parent-Teacher Organization | 501(c)(3) | 2015 | $0 | $0 | 2025-08 |
| Buffalo and Erie County Workforce Investment Board Inc | 501(c)(3) | 2001 | | | |
| Building Education & Trades Inc | 501(c)(3) | 2016 | $0 | $0 | 2025-12 |
| Canisius Crusaders Football Booster S Inc | 501(c)(3) | 2026 | | | |
| Cazenovia Neighborhood Library Inc | 501(c)(3) | 2015 | $0 | $0 | 2025-12 |
| Clarence Youth Center Inc | 501(c)(3) | 2002 | | | |
| Cleveland Hill Sports Booster Club | 501(c)(3) | 2016 | $0 | $0 | 2025-06 |
| Cold Spring Tutor Incorporated | 501(c)(3) | 2022 | $0 | $0 | 2024-01 |
| College Student Personnel Association of New York State | 501(c)(3) | 2014 | | $39,396 | 2025-06 |
| Community Foundation for Greater Buffalo Initiatives Inc | 501(c)(3) | 2024 | $0 | $1 | 2024-12 |
| Csat Foundation Inc | 501(c)(3) | 2020 | $0 | $0 | 2025-12 |
| Discovery School 67 Parent Teacher Organization | 501(c)(3) | 2023 | $0 | $0 | 2026-06 |
| Edward & Alice McLaughlin SCH FD Trust | 501(c)(3) | 1997 | | $114,002 | 2025-09 |
| Empowering Tech for Hutch Tech | 501(c)(3) | 2022 | $0 | $0 | 2025-12 |
| Enssa Foundation Inc | 501(c)(3) | 2026 | | | |
| Erie 1 Boces Educational Foundation Inc | 501(c)(3) | 2022 | $0 | $0 | 2026-06 |
| Eugene Mays and James Bell Scholarship Fund Inc | 501(c)(3) | 1980 | $0 | $0 | 2025-12 |
| Eugene S Richards Memorial Foundation Inc | 501(c)(3) | 2022 | $0 | $0 | 2025-12 |
| First Shiloh Christian Highschool | 501(c)(3) | 1999 | | | |
| Friends of Broderick Park | 501(c)(3) | 2021 | $0 | $0 | 2025-12 |
| Friends of Perimeter Institute Inc | 501(c)(3) | 2003 | | $17,345 | 2025-07 |
| Friends of Tapestry Inc | 501(c)(3) | 2000 | $0 | $0 | 2025-06 |
| Gamma Phi Omega Chapter Housing Development Corp | 501(c)(3) | 1997 | $0 | $0 | 2025-12 |
| Get Out and About Inc | 501(c)(3) | 2023 | $0 | $0 | 2025-12 |
| Guiding Light 716 Inc | 501(c)(3) | 2025 | $0 | $0 | 2025-12 |
| Harvard Club of Western New York | 501(c)(3) | 2026 | $0 | $0 | 2026-08 |
| Havergal College Educational Foundation Inc | 501(c)(3) | 2022 | $0 | $0 | 2025-06 |
| Hcoc Mental Health Corporation | 501(c)(3) | 2025 | $0 | $0 | 2025-12 |
| Healthcare Workers Rising New York Inc | 501(c)(3) | 2024 | | | |
| Helen M Schiffner Scholarship Fund | 501(c)(3) | 2001 | | $119,765 | 2025-12 |
| Hodnicki Family Scholarship Trust | 501(c)(3) | 2011 | | $1.6 million | 2025-12 |
| Hope Unlimited Foundation Inc | 501(c)(3) | 2007 | $0 | $0 | 2025-12 |
| Hutchinson Central Technical High School Alumni Association | 501(c)(3) | 2025 | | | |
| International School 45 Parent Teacher Organization | 501(c)(3) | 2025 | $0 | $0 | 2025-06 |
| Iota Xi Alumni Association of Alpha Tau Omega Inc | 501(c)(3) | 2023 | $0 | $0 | 2025-12 |
| Jesus the Liberator Seminary of Religious Justice | 501(c)(3) | 1997 | | | |
| Kappa Upsilon Zeta Scholarship Foundation Inc | 501(c)(3) | 2022 | $0 | $0 | 2025-12 |
| Kipp Sankofa Charter School | 501(c)(3) | 2003 | | | |
| Kwenu | 501(c)(3) | 2021 | | $1 | 2024-12 |
| Lackawanna Education Extra Curricular Foudation Inc | 501(c)(3) | 2018 | | $34,102 | 2025-12 |
| Louis Henry Gross Sponsorship Foundation | 501(c)(3) | 2010 | | $4.6 million | 2025-12 |
| Marie Obrtlik Scholarship Fund | 501(c)(3) | 2002 | | $549,427 | 2025-12 |
| Marie R Crovat Trust Uw | 501(c)(3) | 2012 | | $1.5 million | 2025-12 |
| Mark E Hamister Family Foundation | 501(c)(3) | 2024 | | | |
| Mary Bigler Hinkle Tuw Scholarship Fund | 501(c)(3) | 2012 | | $544,197 | 2025-12 |
| Minority Bar Foundation Inc | 501(c)(3) | 2004 | $0 | $0 | 2024-12 |
| Miss Buffalo Scholarship Pageant Organization Inc | 501(c)(3) | 2015 | $0 | $0 | 2023-12 |
| Modern Whig Institute | 501(c)(3) | 2019 | $0 | $0 | 2025-12 |
| Montessori Parent Association | 501(c)(3) | 1998 | $0 | $0 | 2026-06 |
| Natania B Parker Foundation Inc | 501(c)(3) | 2021 | $0 | $0 | 2025-12 |
| National Black Mba Assc Western Ny Chapter | 501(c)(3) | 2025 | $0 | $10,233 | 2020-12 |
| New York Silver Society Inc | 501(c)(3) | 1995 | $0 | $0 | 2025-12 |
| New York State Association of European Historians Inc | 501(c)(3) | 2018 | $0 | $0 | 2025-12 |
| New York State Unified Court Law Libraries Association Inc | 501(c)(3) | 2025 | $0 | $0 | 2025-12 |
| North Park Community School 50 Pto | 501(c)(3) | 2020 | $0 | $0 | 2025-12 |
| Olmsted 64 Community Association Inc | 501(c)(3) | 2023 | $0 | $0 | 2025-12 |
| Olmsted Home School Association Inc | 501(c)(3) | 2000 | $0 | $0 | 2025-06 |
| Omega Mentoring Program | 501(c)(3) | 2020 | $0 | $0 | 2024-12 |
| Opera Foundation of Buffalo Inc | 501(c)(3) | 2021 | $0 | $0 | 2025-10 |
| Oracle Charter School | 501(c)(3) | 2004 | $0 | $6,908 | 2025-06 |
| PGM Charles McGarrah & PM George Harris Sr Scholarship Foundation I | 501(c)(3) | 2018 | $0 | $0 | 2025-12 |
| Parent Booster USA Inc | 501(c)(3) | 2005 | $0 | $0 | 2026-04 |
| Pawny Continuing Education Foundation | 501(c)(3) | 2012 | $0 | $0 | 2025-12 |
| Phi Epsilon Chapter of Omega Psi Phi Fraternity Inc | 501(c)(7) | 2024 | | | |
| Phi Eta Sigma National Honor Society Inc | 501(c)(3) | 2014 | | | |
| Phi Omega Chapter-Omega Psi Phi Fraternity Incorporated | 501(c)(7) | 2021 | $0 | $0 | 2023-10 |
| Phi Omega Scholarship Foundation Inc | 501(c)(3) | 2022 | | $31,322 | 2025-12 |
| Phi Sigma Rho National Sorority | 501(c)(7) | 2010 | $0 | $0 | 2025-12 |
| Popstock Educational Services Inc | 501(c)(3) | 2024 | $0 | $0 | 2025-12 |
| QC Early Childhood Foundation | 501(c)(3) | 2024 | | | |
| Reinhardt Family Scholarship Trust | 501(c)(3) | 1997 | | $480,801 | 2025-12 |
| Ricef Inc | 501(c)(3) | 2024 | | | |
| Rotary District 7090 Youth Exchange Program Inc | 501(c)(3) | 2023 | $0 | $0 | 2024-06 |
| Sigma Delta Tau Society | 501(c)(7) | 1948 | $0 | $0 | 2025-06 |
| Snard Cards Inc | 501(c)(3) | 2017 | $0 | $0 | 2025-12 |
| Solid Foundation Prep Inc | 501(c)(3) | 2018 | $0 | $0 | 2025-12 |
| TC Memorial LTD | 501(c)(3) | 2019 | | $1 | 2025-12 |
| Ubmd Dermatology Inc | 501(c)(3) | 2014 | $0 | $0 | 2025-12 |
| Uncrowned Queens Institute for Research & Education On Women Inc | 501(c)(3) | 2003 | $0 | $0 | 2025-12 |
| Unheard Voices Inc | 501(c)(3) | 2025 | | | |
| Universal Education Institute Inc | 501(c)(3) | 2001 | $0 | $0 | 2025-06 |
| Western New York Charter Schools Coalition Inc | 501(c)(3) | 2007 | | | |
| Western New York Network of English Teachers Incorporated | 501(c)(3) | 2022 | $0 | $0 | 2025-12 |
| Western New York Young Achievers Award Inc | 501(c)(3) | 2023 | $0 | $0 | 2025-12 |
| William B Hammond II Ta | 501(c)(3) | 2006 | | $408,383 | 2025-12 |
| Wny Coaches Corner Inc | 501(c)(3) | 2025 | $0 | $0 | 2024-12 |
| Wny Prosperity Fellowship Inc | 501(c)(3) | 2022 | $0 | $0 | 2024-12 |
| Wny Scholars Foundation Inc | 501(c)(3) | 2024 | $0 | $0 | 2025-12 |
| Wny Strong Foundation Inc | 501(c)(3) | 2025 | $0 | $0 | 2025-12 |
| Woodruff Business and Workforce Development | 501(c)(3) | 2024 | $0 | $0 | 2025-12 |
| Mid Atlantic Connection for Pku SND Allied Disorders Inc | 501(c)(3) | 2026 | $-3,016 | $26,521 | 2025-12 |