| Lexington Center Corporation | 501(c)(3) | 2015 | $57.1 million | $353 million | 2025-06 |
| Horseracing Integrity and Safety Authority Inc | 501(c)(6) | 2021 | $50.6 million | $15.8 million | 2024-12 |
| International Coaching Federation Global Enterprise | 501(c)(6) | 2019 | $12.8 million | $22.6 million | 2025-03 |
| Community Ventures Corporation Inc | 501(c)(3) | 1983 | $11.9 million | $100.3 million | 2024-12 |
| Icf Credentialing and Standards | 501(c)(6) | 2020 | $7.5 million | $1.7 million | 2025-03 |
| Icf Coach Training | 501(c)(6) | 2020 | $3.8 million | $1.1 million | 2025-03 |
| American Board of Opticianry | 501(c)(6) | 1998 | $3.3 million | $4.4 million | 2025-06 |
| Lexington Bluegrass Association of Realtors Inc | 501(c)(6) | 2025 | $2 million | $10.9 million | 2025-12 |
| Utility Solid Waste Activities Group | 501(c)(6) | 2025 | $1.9 million | $1.4 million | 2024-12 |
| National Association of Government Defined Contribution Admin Inc | 501(c)(6) | 2003 | $1.7 million | $3 million | 2024-12 |
| The Met Development Inc | 501(c)(3) | 2019 | $1.4 million | $26.1 million | 2024-12 |
| United Opticians Association Inc | 501(c)(6) | 2025 | $1.4 million | $778,156 | 2025-06 |
| CV Appalachian Cde Inc | 501(c)(3) | 2020 | $1.3 million | $5.2 million | 2024-12 |
| Womens Energy Network Inc | 501(c)(6) | 2016 | $1.2 million | $690,534 | 2024-12 |
| Icf Coaching in Organizations Inc | 501(c)(6) | 2020 | $1.2 million | $252,103 | 2025-03 |
| Lexington Strides Ahead Foundation | 501(c)(6) | 1999 | $1.2 million | $191,131 | 2024-12 |
| Commerce Lexington Foundation Inc | 501(c)(3) | 2024 | $1.1 million | $1.1 million | 2024-12 |
| Friends of Coal | 501(c)(6) | 2008 | $967,106 | $1.6 million | 2024-12 |
| National Association of Senior Move Managers | 501(c)(6) | 2003 | $896,652 | $397,825 | 2025-06 |
| Common Good Community Development Corporation | 501(c)(3) | 2012 | $858,805 | $1.2 million | 2024-12 |
| Lexington Lions Club Endowment Inc | 501(c)(3) | 1989 | $750,903 | $3.9 million | 2025-06 |
| Fayette County Local Development Corporation | 501(c)(3) | 1986 | $680,388 | $6.7 million | 2025-06 |
| Robert L Brown Foundation Inc | 501(c)(3) | 2023 | $617,288 | $1.5 million | 2025-06 |
| Collegiate Information and Visitor Services | 501(c)(6) | 2010 | $601,953 | $665,520 | 2026-06 |
| Universal Public Procurement Certification Council | 501(c)(3) | 1999 | $597,809 | $1.4 million | 2024-12 |
| Kentucky Science Teachers Association | 501(c)(3) | 1985 | $543,929 | $96,656 | 2025-06 |
| CPVHC Realty Inc | 501(c)(2) | 2019 | $532,447 | $5.6 million | 2024-12 |
| Lexington Community Radio Inc | 501(c)(3) | 2014 | $528,183 | $258,324 | 2025-12 |
| Accounting and Financial Womens Alliance | 501(c)(6) | 1959 | $412,092 | $126,158 | 2025-06 |
| Seedleaf Inc | 501(c)(3) | 2009 | $392,362 | $179,821 | 2024-12 |
| Central Kentucky Apartment Association Inc | 501(c)(6) | 2003 | $370,624 | $148,311 | 2025-12 |
| One Horizon Institute Inc | 501(c)(3) | 2012 | $344,308 | $22,423 | 2024-12 |
| Kentucky Equine Education Alliance Inc | 501(c)(6) | 2005 | $339,250 | $60,306 | 2025-12 |
| Plumbers and Steamfitters Local No 452 Building Corporation | 501(c)(2) | 2013 | $332,205 | $1.9 million | 2025-06 |
| Insurance Institute of Kentucky Inc | 501(c)(6) | 2017 | $312,123 | $186,446 | 2025-12 |
| Kentucky Individual Self-Insurers Guaranty Fund | 501(c)(6) | 2000 | $304,344 | $14 million | 2025-06 |
| Junior League of Lexington | 501(c)(3) | 1967 | $268,825 | $833,160 | 2024-12 |
| Kentucky Harness Association Inc | 501(c)(6) | 2020 | $250,000 | $764,762 | 2025-12 |
| Northside Common Market | 501(c)(3) | 2020 | $244,578 | $327,679 | 2024-12 |
| National Association of Shell Marketers Inc | 501(c)(6) | 2008 | $234,146 | $20,274 | 2025-12 |
| Business and Education Network Inc | 501(c)(3) | 1999 | $227,365 | $11,015 | 2024-12 |
| Society of Behavioral Sleep Medicine | 501(c)(6) | 2010 | $175,254 | $4,520 | 2025-12 |
| Kentucky Guild of Brewers Inc | 501(c)(6) | 2014 | $155,779 | $38,644 | 2024-12 |
| The Committee of 101 | 501(c)(3) | 1971 | $155,295 | $436,346 | 2026-03 |
| Alpha Beta Lambda Chapter Education Foundation Inc | 501(c)(3) | 2020 | $123,061 | $178,374 | 2025-12 |
| Kentucky Solar Industries Association Inc | 501(c)(6) | 2018 | $121,479 | $8,748 | 2024-12 |
| Lexington for Everyone Inc | 501(c)(4) | 2022 | $120,928 | $64,439 | 2024-12 |
| Franklin Place Inc | 501(c)(3) | 1993 | $112,789 | $344,087 | 2025-06 |
| Lexington Womans Club Inc | 501(c)(3) | 1989 | $99,172 | $208,519 | 2025-05 |
| Racing Officials Accreditationprogram Inc | 501(c)(6) | 2006 | $98,543 | $177,944 | 2025-12 |
| Paddlesports Trade Coalition | 501(c)(6) | 2024 | $92,902 | $37,234 | 2025-12 |
| Empathy & Compassion | 501(c)(3) | 2023 | $88,711 | $61,888 | 2024-12 |
| Kentucky Commonwealth Attorneys Association Inc | 501(c)(6) | 2018 | $84,664 | $175,533 | 2025-12 |
| Lexington Blue Grass Kiwanis Club Endowment Inc | 501(c)(3) | 1984 | $77,535 | $102,089 | 2025-09 |
| Mortgage Bankers Association of Louisville Inc | 501(c)(6) | 2015 | $75,290 | $69,677 | 2024-12 |
| Dealercpa Network Inc | 501(c)(6) | 2019 | $73,872 | $6,710 | 2024-12 |
| Lexington-Bluegrass Area Minority Expo Inc | 501(c)(3) | 2014 | $68,633 | $19,905 | 2024-12 |
| Hearing Aid Association of Kentucky Inc | 501(c)(6) | 2022 | $53,941 | $89,865 | 2025-06 |
| Central Kentucky Association of Health Underwriters Inc | 501(c)(6) | 2007 | $50,446 | $62,006 | 2024-12 |
| Consignors & Commercial Breeders Association Inc | 501(c)(4) | 2006 | $45,550 | $48,473 | 2023-12 |
| Kentucky Center for Performance Excellence | 501(c)(3) | 2008 | $43,900 | $217,693 | 2025-07 |
| Claiming Crown Limited | 501(c)(6) | 1999 | $42,406 | $3,994 | 2025-06 |
| Mortgage Bankers Association of Kentucky Inc | 501(c)(6) | 2017 | $34,154 | $17,775 | 2024-12 |
| Lexington Lodge No 1 Holding Company Inc | 501(c)(2) | 2021 | $29,000 | $991,725 | 2024-12 |
| Us Hemp Authority Inc | 501(c)(6) | 2019 | $23,619 | $2,826 | 2024-12 |
| Bluegrass Tomorrow Inc | 501(c)(3) | 1989 | $3,800 | $4,895 | 2024-12 |
| Fayette Alliance Inc | 501(c)(4) | 2007 | $1,661 | $102,951 | 2025-12 |
| 15 for Freddie Inc | 501(c)(3) | 2022 | $0 | $0 | 2025-12 |
| Bell Court Neighborhood Association Inc | 501(c)(3) | 2005 | $0 | $0 | 2025-12 |
| Bluegrass Area Development District Inc | 501(c)(3) | 2019 | | | |
| Bluegrass Chapter of the International Institute of Busines | 501(c)(6) | 2015 | $0 | $0 | 2025-12 |
| Bluegrass Claims Association Inc | 501(c)(6) | 2013 | $0 | $0 | 2025-12 |
| Bluegrass Pharmacists Association Inc | 501(c)(6) | 2003 | $0 | $0 | 2025-12 |
| Bluegrass Tourism Marketing Association Inc | 501(c)(6) | 2019 | $0 | $0 | 2025-12 |
| Board of Behavioral Sleep Medicine | 501(c)(6) | 2019 | $0 | $0 | 2025-12 |
| Cardinal Valley Park Activity Board Incorporated | 501(c)(3) | 2014 | $0 | $0 | 2025-12 |
| Complexion Community Development Corporation | 501(c)(3) | 2018 | $0 | $0 | 2025-12 |
| Downtown Lexington Corporation Foundation | 501(c)(3) | 2006 | $0 | $3,868 | 2025-12 |
| Empire Builders Foundation | 501(c)(3) | 2024 | $0 | $0 | 2025-12 |
| Endocrine Ethics Association Inc | 501(c)(6) | 2020 | $0 | $0 | 2024-12 |
| Excutive Womans Golf Association Inc | 501(c)(6) | 1997 | $0 | $0 | 2025-12 |
| Fayette County Military Suicide Prevention Coalition Corp | 501(c)(3) | 2025 | | | |
| Georgetown Street Area Neighborhood Association | 501(c)(3) | 2023 | $0 | $0 | 2025-12 |
| Glendover Neighborhood Association | 501(c)(4) | 2013 | $0 | $0 | 2023-12 |
| Greater Gardenside Association LLC | 501(c)(4) | 2024 | $0 | $0 | 2025-12 |
| Here To Help Co | 501(c)(3) | 2024 | $0 | $0 | 2025-12 |
| Historic Courthouse Square Development Inc | 501(c)(3) | 2016 | $0 | $0 | 2024-12 |
| Hope for Congo Ministries Inc | 501(c)(3) | 2017 | $0 | $0 | 2024-12 |
| Idle Hour Neighbors Alliance | 501(c)(4) | 2013 | $0 | $0 | 2025-12 |
| Interfaith Alliance of the Bluegrass Inc | 501(c)(3) | 2005 | $0 | $0 | 2025-12 |
| Irem Kentucky West Virginia Chap 10 4 Inc | 501(c)(6) | 2026 | $0 | $0 | 2021-12 |
| Kaep | 501(c)(6) | 2010 | $0 | $0 | 2025-12 |
| Kentucky Association of County Engineers and Road Supervisors | 501(c)(6) | 2014 | $0 | $0 | 2025-12 |
| Kentucky Athletic Trainers Society | 501(c)(6) | 2015 | $0 | $0 | 2026-06 |
| Kentucky Human Resourcesassociation Inc | 501(c)(6) | 2007 | $0 | $0 | 2025-12 |
| Kentucky Pace Association Inc | 501(c)(6) | 2025 | | | |
| Kentucky Saddlebred Owners Andbreeders Association Inc | 501(c)(6) | 2016 | $0 | $0 | 2025-12 |
| Kentucky Society of Pathologists Inc | 501(c)(6) | 2013 | $0 | $0 | 2025-10 |
| Kids Grow Ky Co | 501(c)(3) | 2024 | | | |
| Leadership Central Kentucky Foundation Inc | 501(c)(3) | 2005 | $0 | $0 | 2026-07 |
| Lextran Foundation Inc | 501(c)(3) | 2015 | $0 | $0 | 2025-06 |
| Living Streets Lexington Inc | 501(c)(3) | 2026 | $0 | $0 | 2025-12 |
| Look Good Feel Good Lexington | 501(c)(3) | 2026 | | | |
| Mack Foundation Inc | 501(c)(3) | 2015 | $0 | $0 | 2025-12 |
| Martin Luther King Neighborhood Association Inc | 501(c)(3) | 2024 | | | |
| Mashindi Medical Missions Inc | 501(c)(3) | 2015 | | $1,500 | 2025-12 |
| Mentelle Neighborhood Association | 501(c)(3) | 2016 | $0 | $0 | 2025-12 |
| Nonprofit Shared Service Center of Central Kentucky Inc | 501(c)(3) | 2026 | | | |
| Northside Improvements Corporation | 501(c)(3) | 2019 | $0 | $0 | 2025-12 |
| One Day at A Time Ministries Inc | 501(c)(3) | 2022 | $0 | $0 | 2025-12 |
| Pralltown Neighborhood Association Inc | 501(c)(3) | 2026 | | | |
| Rotary Club of Lexington Sunrise Foundation Inc | 501(c)(3) | 2014 | $0 | $0 | 2026-06 |
| Runjumpdev Inc | 501(c)(6) | 2014 | $0 | $0 | 2025-12 |
| The Blue Grass Farmers Market Inc | 501(c)(6) | 2010 | $0 | $0 | 2025-12 |
| Transylvania Park Committee | 501(c)(4) | 2014 | $0 | $0 | 2025-12 |
| United Congolese Community Ucc Inc | 501(c)(3) | 2025 | | | |
| William Wells Brown Neighborhood Association | 501(c)(3) | 2025 | $0 | $0 | 2025-12 |