| The Moorings Incorporated | 501(c)(3) | 1978 | $172.5 million | $1.30 billion | 2025-12 |
| Avow Hospice Inc | 501(c)(3) | 1983 | $35.2 million | $41.6 million | 2024-12 |
| Better Together Strengthening Families Inc | 501(c)(3) | 2016 | $20.4 million | $34.8 million | 2024-12 |
| Youth Haven Inc | 501(c)(3) | 1970 | $19.6 million | $33.3 million | 2025-06 |
| The Shelter for Abused Women & Children Inc | 501(c)(3) | 1987 | $16 million | $82.2 million | 2025-06 |
| Grace Place for Children and Families Inc | 501(c)(3) | 2005 | $10.3 million | $18.2 million | 2025-07 |
| Royal Palm Academy Inc | 501(c)(3) | 1999 | $8.3 million | $11.8 million | 2025-06 |
| St Vincent de Paul Society Inc | 501(c)(3) | 2009 | $6.8 million | $8 million | 2025-09 |
| Fun Time Early Childhood Academy Inc | 501(c)(3) | 1964 | $6.1 million | $10.2 million | 2025-06 |
| Baker Senior Center Naples Inc | 501(c)(3) | 2012 | $5.2 million | $22.9 million | 2025-06 |
| Moorings Park Foundation Inc | 501(c)(3) | 2010 | $4.1 million | $9.5 million | 2025-12 |
| New Horizons of Southwest | 501(c)(3) | 2003 | $3 million | $2.6 million | 2025-08 |
| Friends of Foster Children Forever Inc | 501(c)(3) | 2000 | $2.6 million | $2.7 million | 2025-06 |
| The Freedom Institute Inc | 501(c)(3) | 1992 | $2.5 million | $6.8 million | 2025-06 |
| Golden Paws Assistance Dogs Inc | 501(c)(3) | 2013 | $2.5 million | $25.8 million | 2025-12 |
| Southwest Florida Regional Coalition To End Homelessness Inc | 501(c)(3) | 2002 | $1.8 million | $826,480 | 2024-12 |
| Lighthouse of Collier Inc | 501(c)(3) | 2009 | $1.2 million | $3 million | 2024-12 |
| Avow Care Services Incorporated | 501(c)(3) | 2012 | $1.1 million | $4.4 million | 2024-12 |
| Project Build SWFL | 501(c)(3) | 2020 | $878,221 | $268,943 | 2025-12 |
| Beverly S Angels Inc | 501(c)(3) | 2019 | $856,212 | $226,926 | 2025-12 |
| Sunlight of Collier County Inc | 501(c)(3) | 1997 | $601,277 | $744,534 | 2024-12 |
| 2L Foundation | 501(c)(3) | 2023 | $559,305 | $212,062 | 2024-12 |
| Parkinson Association of SW FL Inc | 501(c)(3) | 2013 | $536,929 | $1.2 million | 2025-05 |
| Providence House | 501(c)(3) | 2006 | $491,975 | $2.6 million | 2024-12 |
| Baby Basics of Collier County Inc | 501(c)(3) | 2005 | $458,009 | $1.1 million | 2025-12 |
| Learn2earn Charitable Foundation Inc | 501(c)(3) | 2024 | $445,208 | $1.4 million | 2025-12 |
| Destiny Village Inc | 501(c)(3) | 2002 | $430,121 | $221,495 | 2025-12 |
| Collier Resource Center Inc | 501(c)(3) | 2015 | $380,954 | $335,612 | 2024-12 |
| People for Guatemala Inc | 501(c)(3) | 2010 | $293,609 | $1.9 million | 2025-12 |
| Collier Harvest Foundation | 501(c)(3) | 1992 | $251,946 | $571,465 | 2024-12 |
| Christ Child Society of Naples | 501(c)(3) | 1998 | $249,334 | $823,830 | 2025-06 |
| Friends From Abroad | 501(c)(3) | 2025 | $209,869 | $152,433 | 2025-12 |
| Naples Auto Donation Center Inc | 501(c)(3) | 2012 | $205,678 | $97,362 | 2025-12 |
| E F E P Corp | 501(c)(3) | 2016 | $181,651 | $1 | 2024-12 |
| Rotary Club of Naples Charitable Foundation Inc | 501(c)(3) | 2010 | $170,653 | $865,506 | 2025-06 |
| Brotherhood Ride Inc | 501(c)(3) | 2010 | $143,028 | $608,908 | 2025-12 |
| Let Love International Inc | 501(c)(3) | 2017 | $134,652 | $337,310 | 2024-12 |
| Jacob Transition Safe House Inc | 501(c)(3) | 2021 | $133,685 | $16,750 | 2024-12 |
| Shepherds Answer Inc | 501(c)(3) | 2020 | $128,363 | $69,484 | 2025-12 |
| Project Outreach Inc | 501(c)(3) | 2014 | $115,127 | $138,159 | 2023-12 |
| Northside Naples Kiwanis Foundation Inc | 501(c)(3) | 1997 | $111,162 | $323,339 | 2025-09 |
| Together On Purpose | 501(c)(3) | 2018 | $106,497 | $578 | 2025-12 |
| Community Pregnancy Clinics Foundation Inc | 501(c)(3) | 2022 | $85,660 | $1.3 million | 2025-12 |
| Harbour Island Outreach Inc | 501(c)(3) | 2024 | $84,851 | $48,444 | 2025-12 |
| Trinity Life Foundation Incorporated - Naples Florida | 501(c)(3) | 2019 | $73,401 | $85,831 | 2025-12 |
| Kiwanis Club of Naples-On-The-Gulf Florida Foundation Inc | 501(c)(3) | 2019 | $59,729 | $41,555 | 2025-09 |
| Grace Works Unlimited Inc | 501(c)(3) | 2010 | $38,900 | $15,529 | 2025-12 |
| Advocates for Disabled Americans-Veterans | 501(c)(3) | 2013 | $19,250 | $1 | 2024-12 |
| Women of God Ministries International Inc | 501(c)(3) | 2021 | $11,201 | $179 | 2024-01 |
| Christmas in July Foundation of Collier County Inc | 501(c)(3) | 2019 | $5,133 | $2,012 | 2025-12 |
| Supportive Souls Inc | 501(c)(3) | 2025 | $5,000 | $4,946 | 2025-12 |
| Robert L Zore Foundation Inc | 501(c)(3) | 2019 | $1,898 | $907 | 2025-12 |
| Bondage2freedom Inc | 501(c)(3) | 2023 | $1,600 | $2,583 | 2025-12 |
| Proyecto Mi Hogar Inc | 501(c)(3) | 2026 | $1,475 | $1 | 2024-12 |
| Community Advance Resources and Education Inc | 501(c)(3) | 2011 | $350 | $15,000 | 2025-12 |
| 4 Helping Other People Enhance | 501(c)(3) | 2007 | $0 | $0 | 2024-12 |
| A Touch of Love Legacy Project Corporation | 501(c)(3) | 2023 | $0 | $0 | 2026-01 |
| Agape Partners Inc | 501(c)(3) | 2008 | $0 | $0 | 2025-12 |
| Alienated Grandparents Anonymous Incorporated | 501(c)(3) | 2012 | $0 | $0 | 2025-12 |
| Altruism Project Corporation | 501(c)(3) | 2024 | | | |
| American Gold Star Mothers of Southwest Florida Inc | 501(c)(3) | 2019 | $0 | $0 | 2026-06 |
| American Veterans Emergency Response Team Inc | 501(c)(3) | 2022 | $0 | $0 | 2025-12 |
| Beacon of Hope Foundation | 501(c)(3) | 2008 | $0 | $0 | 2025-12 |
| Beauty Holiday Inc | 501(c)(3) | 2024 | $0 | $0 | 2025-12 |
| Betty Carew Foundation | 501(c)(3) | 2019 | $0 | $0 | 2025-12 |
| Big Hearts Foundation | 501(c)(3) | 2026 | | | |
| C3 Cafe Naples Inc | 501(c)(3) | 2021 | $0 | $0 | 2024-12 |
| Canji International Foundation Inc | 501(c)(3) | 2018 | $0 | $0 | 2025-12 |
| Cari Beths Blessings Inc | 501(c)(3) | 2024 | | $5.9 million | 2024-12 |
| Cassaday Family Foundation Inc | 501(c)(3) | 2025 | | | |
| Celebrity Martini Glass Auction Inc | 501(c)(3) | 2025 | $0 | $0 | 2025-12 |
| Citizens Foster Care Review Board Inc | 501(c)(3) | 2022 | $0 | $0 | 2025-12 |
| Copcare 20 Inc | 501(c)(3) | 2021 | $0 | $0 | 2024-12 |
| Cypress Palm Middle School Ptso | 501(c)(3) | 2024 | $0 | $0 | 2026-06 |
| Disability and Special Needs Encyclopedia Inc | 501(c)(3) | 2017 | $0 | $0 | 2025-12 |
| Dolphreakys Phriends Inc | 501(c)(3) | 2022 | $0 | $0 | 2025-12 |
| East Naples Kiwanis Florida Foundation Inc | 501(c)(3) | 2009 | $0 | $0 | 2025-09 |
| Empower Wheels Now Inc | 501(c)(3) | 2025 | $0 | $0 | 2025-12 |
| Enkind Org Inc | 501(c)(3) | 2026 | | | |
| Fabela Family Foundation | 501(c)(3) | 1998 | | $1.1 million | 2025-12 |
| Family To Family Kids Crisis Closet Inc | 501(c)(3) | 2018 | $0 | $0 | 2024-12 |
| Fearless Voices Inc | 501(c)(3) | 2024 | | | |
| Fit for Kids | 501(c)(3) | 2025 | | | |
| Foster Village Southwest Florida | 501(c)(3) | 2023 | $0 | $0 | 2023-12 |
| Foundyller Save the Children Charit Able Corporation | 501(c)(3) | 2026 | | $700,000 | 2025-12 |
| Generous Hearts Inc | 501(c)(3) | 2022 | $0 | $0 | 2025-12 |
| Geriserve Incorporated | 501(c)(3) | 2026 | | | |
| Grey Oaks Cares Foundation Inc | 501(c)(3) | 2026 | | | |
| Growtogether Foundation Inc | 501(c)(3) | 2025 | | | |
| Gulf Coast Poodle Club & Rescue Inc | 501(c)(3) | 2014 | $0 | $0 | 2026-02 |
| Healthy Wealthy Wise Network Inc | 501(c)(3) | 2023 | $0 | $0 | 2025-12 |
| Honeysuckle Foundation for Children With Cancer | 501(c)(3) | 2004 | $0 | $0 | 2025-12 |
| Hope for Al Amylodosis Incorporated | 501(c)(3) | 2025 | $0 | $0 | 2025-12 |
| Hope for Bombardopolis Non-Profit Organization Inc | 501(c)(3) | 2023 | | | |
| I Have A Dream Food for Haiti Inc | 501(c)(3) | 2025 | | | |
| Idd Consultants of Florida Inc | 501(c)(3) | 2025 | $0 | $0 | 2024-12 |
| Ilormises Legal Clinic Help Feed This Family Inc | 501(c)(3) | 2007 | $0 | $0 | 2025-12 |
| India Association of Naples Inc | 501(c)(3) | 2013 | $0 | $0 | 2025-12 |
| Ixchel Caribe Foundation Inc | 501(c)(3) | 2022 | $0 | $0 | 2025-12 |
| Jon Denzer Bear Hug Foundation | 501(c)(3) | 2020 | | $545,730 | 2025-12 |
| Journal for Change Inc | 501(c)(3) | 2022 | $0 | $0 | 2025-12 |
| Kairos Coalition | 501(c)(3) | 2010 | $0 | $0 | 2024-12 |
| Kiffney Foundation | 501(c)(3) | 2022 | | $440,673 | 2024-12 |
| Latinos239 Foundation Inc | 501(c)(3) | 2026 | $0 | $0 | 2025-12 |
| Life Community International Inc | 501(c)(3) | 2024 | $0 | $0 | 2025-12 |
| MSM Foundation | 501(c)(3) | 2022 | $0 | $3,162 | 2024-12 |
| Marc Moyal Foundation Inc | 501(c)(3) | 2025 | | | |
| Marias Birthday Wishes for the Homeless Inc | 501(c)(3) | 2010 | $0 | $0 | 2025-12 |
| Miracles Among Us Inc | 501(c)(3) | 2009 | $0 | $0 | 2025-12 |
| Moments That Matter Foundation Inc | 501(c)(3) | 2025 | | | |
| Moms Club | 501(c)(3) | 2001 | $0 | $0 | 2026-06 |
| Name My Virtues | 501(c)(3) | 2019 | $0 | $0 | 2024-12 |
| Naples Retreat Inc | 501(c)(3) | 2024 | | $80,687 | 2024-12 |
| Naples Sports Foundation Inc | 501(c)(3) | 1995 | $0 | $0 | 2025-12 |
| New Vision for Porrier Haiti Inc | 501(c)(3) | 2024 | | | |
| Park Valley Foundation Inc | 501(c)(3) | 2025 | | | |
| Peters Presents | 501(c)(3) | 2021 | $0 | $0 | 2025-12 |
| Phelan Family Foundation Inc | 501(c)(3) | 2010 | | $6.4 million | 2024-12 |
| Play for the Mind Foundation | 501(c)(3) | 2025 | $0 | $0 | 2025-12 |
| Polska Przystan Inc | 501(c)(3) | 2026 | $0 | $0 | 2025-12 |
| Power To the Period Foundation Inc | 501(c)(3) | 2022 | $0 | $0 | 2025-12 |
| Primary Purpose Rides | 501(c)(3) | 2025 | | | |
| Rebloom Collective Inc | 501(c)(3) | 2025 | $0 | $0 | 2025-12 |
| Reoso Foundation | 501(c)(3) | 2014 | | $2.8 million | 2025-12 |
| Rok Ripples of Kindness Foundation Inc | 501(c)(3) | 2021 | $0 | $0 | 2024-12 |
| Rolling Thunder Inc | 501(c)(4) | 1996 | $0 | $0 | 2025-12 |
| Rotary Club of Naples Bay Foundation Corporation | 501(c)(3) | 2017 | $0 | $0 | 2025-06 |
| SWFL Veterans Alliance Inc | 501(c)(3) | 2016 | $0 | $0 | 2025-12 |
| Sanctuary of Southwest Florida Inc | 501(c)(3) | 2014 | $0 | $0 | 2025-12 |
| Senior Assist Inc | 501(c)(3) | 2016 | $0 | $0 | 2025-12 |
| Service After Service | 501(c)(3) | 2026 | | | |
| She Is Us United Inc | 501(c)(3) | 2025 | $0 | $0 | 2025-12 |
| Shecangivelove Inc | 501(c)(3) | 2022 | $0 | $0 | 2024-12 |
| Signed With Love From Marie Inc | 501(c)(3) | 2025 | | | |
| Sofis Place | 501(c)(3) | 2026 | $0 | $0 | 2025-04 |
| Sophie S Change for Change Inc | 501(c)(3) | 2024 | $0 | $0 | 2026-01 |
| Sos Colombia | 501(c)(3) | 2023 | $0 | $0 | 2025-12 |
| Stronger Futures Foundation Inc | 501(c)(3) | 2026 | $0 | $0 | 2025-12 |
| Students and Allies for Equality in C | 501(c)(3) | 2025 | | | |
| Supernal World Creations | 501(c)(3) | 2019 | | $633,582 | 2024-12 |
| Techswfl Inc | 501(c)(3) | 2021 | $0 | $0 | 2025-12 |
| The Ohr Yaakov Foundation | 501(c)(3) | 2026 | | | |
| The Together Project Naples Corp | 501(c)(3) | 2025 | | | |
| The@bridge for Women Inc | 501(c)(3) | 2026 | | | |
| Themis Alliance | 501(c)(3) | 2024 | $0 | $0 | 2024-12 |
| Universal Globe Masters Florida Inc | 501(c)(3) | 2007 | $0 | $0 | 2025-12 |
| Voices of Naples Inc | 501(c)(3) | 2003 | $0 | $0 | 2025-06 |
| Waterfront Warriors South Inc | 501(c)(3) | 2016 | $0 | $0 | 2024-12 |
| Waymaker Foundation | 501(c)(3) | 2024 | | $9,002 | 2025-12 |
| Wendy S Village Inc | 501(c)(3) | 2026 | | | |
| Women for Wounded Warriors | 501(c)(3) | 2012 | $0 | $0 | 2025-12 |
| Yachts for Tots International Inc | 501(c)(3) | 2023 | $0 | $0 | 2025-12 |
| Younited Financial Company | 501(c)(3) | 2024 | $0 | $0 | 2025-05 |
| Naples Take A Soldier Fishing Inc | 501(c)(3) | 2014 | $-8,507 | $100,370 | 2025-12 |