Data / Nonprofits / North Carolina / Science and technology
Science and technology nonprofits in North Carolina: 185 registered with the IRS
185 science and technology nonprofits are registered with the IRS in North Carolina, 175 of them 501(c)(3) charities; the 49 that report revenue took in $1.39 billion. The most are in Raleigh (31), Durham (17), Chapel Hill (15). The largest by revenue: Research Triangle Institute ($1.25 billion), MCNC ($74.1 million), North Carolina Biotechnology Center ($21 million).
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Every organization, largest by revenue first
| Organization | City | Type | Since | Revenue | Assets | Filing |
|---|---|---|---|---|---|---|
| Research Triangle Institute | RTP | 501(c)(3) | 1960 | $1.25 billion | $947.4 million | 2025-09 |
| MCNC | R Triangle Park | 501(c)(3) | 1980 | $74.1 million | $175.1 million | 2025-06 |
| North Carolina Biotechnology Center | Durham | 501(c)(3) | 1985 | $21 million | $42.2 million | 2025-06 |
| Isothermal Planning and Development Corporation | Rutherfordton | 501(c)(3) | 1975 | $13.9 million | $7.5 million | 2025-06 |
| MCNC Endowment | Research Triangle Park | 501(c)(3) | 2001 | $6.1 million | $168.5 million | 2025-06 |
| Wireless Research Center of North Carolina | Wake Forest | 501(c)(3) | 2011 | $3.7 million | $1.4 million | 2025-09 |
| Real Estate Standards Organization | Raleigh | 501(c)(6) | 2012 | $3.3 million | $3.4 million | 2025-12 |
| International Union of Pure and Applied Chemistry | Durham | 501(c)(3) | 1953 | $2.6 million | $7.5 million | 2024-12 |
| The Rna Society | Raleigh | 501(c)(3) | 1995 | $2 million | $3.8 million | 2024-12 |
| Muddy Sneakers Inc | Raleigh | 501(c)(3) | 2008 | $1.5 million | $1.7 million | 2025-06 |
| Institute of Digital Engineering USA | Mooresville | 501(c)(3) | 2022 | $1.3 million | $1.7 million | 2025-12 |
| Education and Research Consortium of Western North Carolina | Asheville | 501(c)(3) | 1999 | $898,036 | $14.1 million | 2025-12 |
| North Carolina Center for Automotive Research Inc | Garysburg | 501(c)(3) | 2006 | $791,906 | $7.4 million | 2025-12 |
| Pisgah Astronomical Research Institute | Rosman | 501(c)(3) | 1999 | $727,738 | $17.6 million | 2024-12 |
| Live Learn Innovate Foundation | Raleigh | 501(c)(3) | 2018 | $505,056 | $219,767 | 2025-12 |
| Society for Acupuncture Research Inc | Winston Salem | 501(c)(3) | 1996 | $446,047 | $64,302 | 2025-12 |
| Hubzone Technology Initiative Inc | Henderson | 501(c)(3) | 2019 | $363,940 | $52,771 | 2025-12 |
| Rci-Iibec Foundation Inc | Raleigh | 501(c)(3) | 2000 | $296,489 | $789,449 | 2025-12 |
| Mathematical Metaphysics Institute | Sanford | 501(c)(3) | 2023 | $275,932 | $35,591 | 2024-12 |
| Plastic Ocean Project Inc | Wilmington | 501(c)(3) | 2014 | $237,608 | $190,784 | 2024-12 |
| Symbioseas | Carolina BCH | 501(c)(3) | 2014 | $199,210 | $26,769 | 2025-12 |
| Its Carolinas Inc | Raleigh | 501(c)(3) | 2020 | $163,609 | $65,114 | 2025-12 |
| Ech Institute Inc | Cary | 501(c)(3) | 2025 | $149,254 | $247,013 | 2025-12 |
| Impactstats Inc | Wake Forest | 501(c)(3) | 2023 | $137,732 | $111,435 | 2025-07 |
| Port Discover Northeastern North Carolinas Center for Hands On Scie | Elizabeth Cty | 501(c)(3) | 2005 | $134,236 | $417,824 | 2025-06 |
| Southeastern Residency Conference Inc | Wallace | 501(c)(3) | 2001 | $133,916 | $51,872 | 2024-12 |
| North Carolina Arcgis Users Group Inc | Raleigh | 501(c)(6) | 2012 | $116,616 | $40,710 | 2025-12 |
| Bent Creek Institute Inc | Asheville | 501(c)(3) | 2010 | $111,829 | $245,603 | 2025-06 |
| Liquid Rocketry Lab | Raleigh | 501(c)(3) | 2019 | $102,271 | $169,998 | 2025-12 |
| Lake Norman It Professionals | Cornelius | 501(c)(4) | 2022 | $101,876 | $146,517 | 2024-12 |
| Cape Fear Bird Observatory Inc | Wilmington | 501(c)(3) | 2021 | $101,342 | $32,414 | 2025-12 |
| Triangle Biotech Tuesday | Durham | 501(c)(3) | 2023 | $91,660 | $54,216 | 2025-12 |
| Foundation for Shackleford Horses Inc | Beaufort | 501(c)(3) | 1997 | $87,708 | $76,769 | 2025-12 |
| Group for the Research of Intelligent Agent Networked Techno | Mars Hill | 501(c)(3) | 2021 | $76,667 | $1 | 2024-12 |
| Western North Carolina Human Resources Association | Asheville | 501(c)(6) | 2017 | $66,711 | $150,497 | 2025-12 |
| Bluenanta | Asheville | 501(c)(3) | 2024 | $48,730 | $48,684 | 2025-12 |
| NC Stem Academy | Cary | 501(c)(3) | 2021 | $46,892 | $924 | 2024-12 |
| DNN Association Inc | Raleigh | 501(c)(3) | 2018 | $37,551 | $49,801 | 2025-12 |
| International Technology Center | RTP | 501(c)(3) | 2001 | $33,642 | $276,431 | 2024-12 |
| Generational Radiation Impact Project Inc | Candler | 501(c)(3) | 2017 | $27,278 | $43,543 | 2025-12 |
| Blue Heart Wellness | Chapel Hill | 501(c)(3) | 2025 | $17,500 | $5,833 | 2025-12 |
| Neuroscience Group | Chapel Hill | 501(c)(3) | 2018 | $15,000 | $5,643 | 2025-06 |
| Alward Institute for Collaborative Science | Kannapolis | 501(c)(3) | 2015 | $11,687 | $4,610 | 2025-12 |
| Institute for Patient-Centered Design Inc | Winterville | 501(c)(3) | 2011 | $11,562 | $14,497 | 2024-12 |
| North Carolina Science Leadership Association | Bermuda Run | 501(c)(3) | 2018 | $8,286 | $215,912 | 2025-08 |
| Family Business Ethics Institute Inc | Cornelius | 501(c)(3) | 2024 | $6,586 | $2,654 | 2025-12 |
| Foundation for Ethical Recycling of Industrial Scrap Corp | Cornelius | 501(c)(3) | 2024 | $6,147 | $352 | 2025-12 |
| Ohms FTC21501 | Hillsborough | 501(c)(3) | 2025 | $5,634 | $3,896 | 2025-07 |
| James Black Memorial Classic | Charlotte | 501(c)(3) | 2025 | $3,260 | $1,460 | 2025-12 |
| Ai Psychological Research Coalition | Hendersonvlle | 501(c)(3) | 2026 | |||
| Air-Pruning Technologies | Raleigh | 501(c)(3) | 1999 | $2.2 million | 2024-12 | |
| All Things Linux | Charlotte | 501(c)(3) | 2024 | $0 | $0 | 2025-12 |
| American Society for Cytotechnologyfoundation | Raleigh | 501(c)(3) | 2008 | $0 | $0 | 2025-06 |
| American Society for Standards in Mediumship & Psychical Investigati | Flat Rock | 501(c)(3) | 2015 | $0 | $0 | 2025-12 |
| American Society of Pharmacovigilance Physicians Inc | Durham | 501(c)(3) | 2022 | $0 | $0 | 2025-12 |
| Anderson Robotics | Durham | 501(c)(3) | 2024 | $0 | $0 | 2025-12 |
| Aquapack Robotics | Raleigh | 501(c)(3) | 2022 | $0 | $0 | 2025-12 |
| Arborcrest Gardens Inc | Boone | 501(c)(3) | 1989 | $3.4 million | 2024-12 | |
| Asheville Institute for Memory and Longevity Inc | Mills River | 501(c)(3) | 2026 | |||
| Aureole Foundation | Wake Forest | 501(c)(3) | 2026 | |||
| Automotive Security Research Group | Southport | 501(c)(3) | 2019 | $11,621 | 2025-12 | |
| Awmna | Stallings | 501(c)(3) | 2022 | $4,888 | 2024-12 | |
| B-Sides Rdu | Cary | 501(c)(3) | 2024 | $14,199 | 2025-12 | |
| Bee Geek Inc | Winston Salem | 501(c)(3) | 2018 | $0 | $0 | 2025-12 |
| Best Practices for Non-Targeted Analysis | Morrisville | 501(c)(3) | 2024 | $0 | $0 | 2026-04 |
| Beytek Information Technology Organization | Warrenton | 501(c)(3) | 2003 | $0 | $0 | 2025-12 |
| Black Biomechanists Association | Salisbury | 501(c)(3) | 2022 | $0 | $0 | 2026-06 |
| Black Butterfly Org Inc | Wilmington | 501(c)(3) | 2022 | $0 | $0 | 2025-12 |
| Bloomb Health Alliance | Raleigh | 501(c)(3) | 2026 | |||
| Blue Ridge Ruby | Candler | 501(c)(3) | 2024 | $361 | 2025-12 | |
| Build A Better Tomorrows Inc | Morrisville | 501(c)(3) | 2019 | $0 | $0 | 2024-12 |
| Build Bots NC | Pfafftown | 501(c)(3) | 2026 | |||
| Bullcitydao | Chapel Hill | 501(c)(3) | 2024 | $0 | $0 | 2025-12 |
| Burke Weather | Morganton | 501(c)(3) | 2016 | $0 | $0 | 2025-12 |
| Caac Stewardship Foundation Inc | Charlotte | 501(c)(3) | 2018 | $0 | $0 | 2025-09 |
| Cape Fear Astronomical Society | Wilmington | 501(c)(3) | 2020 | $0 | $0 | 2025-12 |
| Cape Fear Makers Guild | Wilmington | 501(c)(3) | 2022 | $0 | $0 | 2025-12 |
| Carolina Electric Vehicle Coalition Inc | Raleigh | 501(c)(3) | 2000 | $0 | $0 | 2025-06 |
| Castle Crash Society | Charlotte | 501(c)(3) | 2024 | $0 | $0 | 2026-02 |
| Catawba Valley Gem & Mineral Club Inc | Hickory | 501(c)(3) | 2019 | $0 | $0 | 2025-06 |
| Center for Quantitative Cytometry | Durham | 501(c)(3) | 1996 | $0 | $0 | 2025-12 |
| Central Iowa Java Users Group Corporation | Apex | 501(c)(3) | 2017 | $0 | $0 | 2025-12 |
| Chapter 309 of the Experimental Aircraft Association Inc | Mooresville | 501(c)(3) | 2006 | $0 | $0 | 2025-12 |
| Clean Water Science Network | Durham | 501(c)(3) | 2017 | $0 | $0 | 2025-12 |
| Climate Cooperators | Raleigh | 501(c)(3) | 2017 | $0 | $0 | 2025-06 |
| Cognitive Immunology Research Collaborative | Greensboro | 501(c)(3) | 2021 | $0 | $0 | 2025-12 |
| Colab Inc | Winston Salem | 501(c)(3) | 2013 | $0 | $0 | 2025-12 |
| Conopa Inc | Washington | 501(c)(3) | 2007 | $0 | $0 | 2025-12 |
| Critical Overload | Cary | 501(c)(3) | 2018 | $0 | $0 | 2026-06 |
| Cui Family Foundation | Raleigh | 501(c)(3) | 2025 | $1 | 2025-12 | |
| Cybertexh One Inc | Charlotte | 501(c)(3) | 2024 | |||
| Defense Alliance Foundation | Durham | 501(c)(3) | 2025 | $0 | $1 | 2025-12 |
| Digital Skills for Ownership and Sustainability | Havelock | 501(c)(3) | 2025 | $0 | $0 | 2025-12 |
| Duke University Medical Physics Alumni Association | Raleigh | 501(c)(3) | 2024 | $0 | $0 | 2025-12 |
| Durham Makerspace | Durham | 501(c)(3) | 2012 | $0 | $0 | 2025-12 |
| Electric Vehicle Energy Research of Nebraska Inc | Chapel Hill | 501(c)(3) | 2016 | $0 | $0 | 2025-12 |
| Energy Mashup Lab Inc | Pittsboro | 501(c)(3) | 2014 | $0 | $0 | 2026-06 |
| Eno Innovation Foundation | Chapel Hill | 501(c)(3) | 2026 | |||
| Entrepreneur Leadership Institute | Pleasant GDN | 501(c)(3) | 2012 | $0 | $0 | 2026-06 |
| Environmental Genome Initiative | Raleigh | 501(c)(3) | 2017 | $0 | $0 | 2025-12 |
| Fenbendazole Foundation | Wake Forest | 501(c)(3) | 2024 | $55,952 | 2024-12 | |
| Flasc Inc | Greensboro | 501(c)(3) | 2015 | $0 | $0 | 2025-12 |
| Foglift Innovation Enterprises Inc | Fuquay Varina | 501(c)(3) | 2021 | $0 | $0 | 2025-12 |
| Forestregen Climate Initiative Inc | Clayton | 501(c)(3) | 2024 | $0 | $0 | 2025-12 |
| Foretell Foundation | Waxhaw | 501(c)(3) | 2024 | |||
| Forsyth Astronomical Society | Winston Salem | 501(c)(3) | 2021 | $0 | $0 | 2026-04 |
| Globalnet Outreach Inc | Cary | 501(c)(3) | 2024 | |||
| Ground Water Professionals of North Carolina | Cary | 501(c)(3) | 2014 | $0 | $0 | 2025-12 |
| Heart Rate Variability Institute Inc | Chocowinity | 501(c)(3) | 2023 | $3,799 | 2024-05 | |
| Heist Think Tank | Charlotte | 501(c)(3) | 2024 | $0 | $0 | 2024-12 |
| Help the Web Inc | Raleigh | 501(c)(3) | 2024 | $0 | $0 | 2025-12 |
| Hpi Research & Education Services Non Profit Inc | Durham | 501(c)(3) | 2010 | $0 | $0 | 2025-12 |
| Iasmirt | Raleigh | 501(c)(3) | 2018 | $0 | $0 | 2025-12 |
| Innovate Tech Charlotte | Charlotte | 501(c)(3) | 2020 | $0 | $0 | 2025-12 |
| Innovateconnect Inc | Holly Springs | 501(c)(3) | 2023 | $7,723 | 2023-12 | |
| Institute for International Maritime Research | Washington | 501(c)(3) | 1994 | $0 | $0 | 2025-12 |
| International Association of Forens Ic Toxicology Consultants | Cary | 501(c)(6) | 2026 | $0 | $0 | 2025-12 |
| Isc2 Raleigh Durham Chapter | Rougemont | 501(c)(3) | 2015 | $0 | $0 | 2025-12 |
| K9 Too NC | Raleigh | 501(c)(3) | 2025 | $0 | $0 | 2025-12 |
| Kindle Architects Association | Raleigh | 501(c)(3) | 2024 | $0 | $0 | 2025-12 |
| Ksea Eastern Carolina Chapter Inc | Greenville | 501(c)(3) | 2018 | $0 | $0 | 2025-06 |
| Ksea NC Chapter | Cary | 501(c)(3) | 2016 | $0 | $0 | 2026-06 |
| Latenttech | Raleigh | 501(c)(3) | 2024 | |||
| Light-Year Astronomical Association | Nashville | 501(c)(3) | 2024 | $0 | $0 | 2025-12 |
| Livnocean Research Inc | Southport | 501(c)(3) | 2025 | $0 | $0 | 2025-12 |
| Localaiservers Collective | Greensboro | 501(c)(3) | 2026 | |||
| M2 Stem Opportunities Inc | Concord | 501(c)(3) | 2019 | $0 | $0 | 2023-12 |
| Magic of Science | Chapel Hill | 501(c)(3) | 2024 | $0 | $717 | 2025-06 |
| Manus Foundation | Greensboro | 501(c)(3) | 2026 | |||
| Matthews Community Robotics | Matthews | 501(c)(3) | 2018 | $0 | $0 | 2025-12 |
| McCulloch Foundation Inc | Jamestown | 501(c)(3) | 2000 | $3,856 | 2023-12 | |
| Merrow Foundation | Morehead City | 501(c)(3) | 2016 | $0 | $0 | 2025-12 |
| Mersenne Research Inc | Blowing Rock | 501(c)(3) | 2019 | $0 | $0 | 2025-12 |
| Metrolina Engineering Professionals | Charlotte | 501(c)(3) | 2026 | |||
| Mount Cyllene | Greensboro | 501(c)(3) | 2022 | $0 | $1,275 | 2025-12 |
| NC Idea | Durham | 501(c)(3) | 2002 | $51.6 million | 2025-06 | |
| National Association of Forensic Science Boards | Morrisville | 501(c)(3) | 2024 | $0 | $0 | 2024-12 |
| National Education Association Retirees Organization | Currituck | 501(c)(7) | 1999 | $0 | $0 | 2024-12 |
| National Society of Black Engineers | Durham | 501(c)(3) | 2015 | $0 | $0 | 2026-05 |
| Ncai Research | Mars Hill | 501(c)(3) | 2025 | |||
| North Carolina Academy of Research and Development Inc | Chapel Hill | 501(c)(3) | 2024 | $0 | $1 | 2024-12 |
| North Carolina Chinese Scholars Sino-Us Exchange Association | Durham | 501(c)(3) | 2017 | $3,261 | 2024-12 | |
| North Carolina Oncology Navigator Association | Chapel Hill | 501(c)(3) | 2014 | $0 | $0 | 2025-06 |
| North Carolina Pecan Growers Association Inc | Louisburg | 501(c)(3) | 2013 | $0 | $0 | 2025-12 |
| Oceansource Technology Foundation Ostf | Cary | 501(c)(3) | 2021 | $0 | $0 | 2023-12 |
| Old Hollis School Research and Educ Ation Center | Ellenboro | 501(c)(3) | 2025 | $0 | $0 | 2025-12 |
| Open Metaverse Federation | Raleigh | 501(c)(3) | 2018 | $0 | $0 | 2025-12 |
| Open S2 | Angier | 501(c)(3) | 2024 | $0 | $0 | 2025-12 |
| Open Source in Pharma | Pittsboro | 501(c)(3) | 2022 | $0 | $0 | 2025-12 |
| Openpra Org | Raleigh | 501(c)(3) | 2025 | |||
| Orchidroots Corporation | Asheville | 501(c)(3) | 2017 | $88,465 | 2025-12 | |
| Organization of Datum Clinical Research | Lewisville | 501(c)(3) | 2017 | $0 | $0 | 2023-12 |
| Paradox Institute | Pfafftown | 501(c)(3) | 2025 | $0 | $0 | 2025-12 |
| Pauli Murray LGBTQ Bar Association | Weddington | 501(c)(6) | 2023 | $0 | $0 | 2025-08 |
| Pharmasug | Chapel Hill | 501(c)(6) | 2026 | $0 | $0 | 2025-12 |
| Pirl Foundation | Chapel Hill | 501(c)(3) | 2021 | $0 | $0 | 2025-12 |
| Quest Gate | Fayetteville | 501(c)(3) | 2025 | |||
| Research Triangle Park Bioscience and Biotechnology Meeting | Chapel Hill | 501(c)(3) | 2012 | $0 | $0 | 2024-12 |
| Retri Network | Chapel Hill | 501(c)(3) | 2026 | |||
| SRC Manufacturing Consortium Corporation | Durham | 501(c)(6) | 2024 | $0 | $0 | 2024-12 |
| Safetech NC | Fairview | 501(c)(3) | 2025 | $0 | $0 | 2025-12 |
| Science for Healthy Families | New Hill | 501(c)(3) | 2025 | |||
| Scientific Research and Education Network | Beaufort | 501(c)(3) | 2015 | $0 | $0 | 2025-12 |
| Smoky Mountain Scientific | Cullowhee | 501(c)(3) | 2016 | $0 | $0 | 2025-12 |
| Society for the Metaphysics of Science | Raleigh | 501(c)(3) | 2019 | $0 | $0 | 2023-06 |
| Solar Pack | Raleigh | 501(c)(3) | 2019 | $0 | $0 | 2025-12 |
| Solcycle Inc | Chapel Hill | 501(c)(3) | 2022 | $0 | $0 | 2025-12 |
| Star U Are | Clayton | 501(c)(3) | 2016 | $0 | $0 | 2025-12 |
| Static Robotics Board | Holly Springs | 501(c)(3) | 2023 | $0 | $0 | 2025-06 |
| Sunlight Foundation Inc | Leicester | 501(c)(3) | 2006 | $0 | $0 | 2025-12 |
| Tar Heel Gem & Mineral Club Inc | Raleigh | 501(c)(3) | 2001 | $0 | $0 | 2024-12 |
| Team Genius Squad Inc | Durham | 501(c)(3) | 2021 | $0 | $0 | 2025-12 |
| Techno Wolves Robotics Booster Club | Raleigh | 501(c)(3) | 2015 | $0 | $0 | 2026-06 |
| Technology Solutions Xchange Inc | Raleigh | 501(c)(6) | 2025 | $0 | $0 | 2025-12 |
| The Carolina Geological Society Inc | Chapel Hill | 501(c)(3) | 2025 | |||
| The Shodor Education Foundation Inc | Durham | 501(c)(3) | 1995 | $0 | $0 | 2024-12 |
| The Widernet Project | Raleigh | 501(c)(3) | 2014 | $0 | $0 | 2025-12 |
| Third Millennium Foundation Inc | Henderson | 501(c)(3) | 1999 | $0 | $0 | 2023-12 |
| Thomas Research and Education Institute | Creedmoor | 501(c)(3) | 2025 | $0 | $0 | 2025-12 |
| Tri-County Amateur Radio Club | Thomasville | 501(c)(3) | 2021 | $0 | $0 | 2025-12 |
| Triangle Aerial Drone Association | Chapel Hill | 501(c)(3) | 2023 | $0 | $0 | 2025-12 |
| Triangle Association for Scientific Creationism | RTP | 501(c)(3) | 1996 | $0 | $0 | 2024-12 |
| Wood Duck Research Inc | Mooresville | 501(c)(3) | 2018 | $0 | $0 | 2025-12 |
| Xdirective Inc | Charlotte | 501(c)(3) | 2024 | $0 | $0 | 2024-12 |
| Zebracorns Inc | Durham | 501(c)(3) | 2017 | $0 | $0 | 2024-12 |
Every nonprofit in North Carolina
Read from the IRS Exempt Organizations Business Master File, updated by the IRS on October 24, 2026 and rebuilt here every morning. Revenue and assets are from each organization's latest filing as the IRS lists it; the IRS record is the official one. Organizations only: no people are named on these pages.