| Morrison Healthcare | July 21, 2026 | | 86 | Pascagoula and Ocean Springs, Jackson County | Closure | | mdes.ms.gov |
| Hood Industries | July 6, 2026 | September 5, 2026 | 259 | Wiggins, Stone County | Closure | | mdes.ms.gov |
| Conduent Commercial Solutions, LLC | June 29, 2026 | August 28, 2026 | 35 | Remote – Statewide, Remote – Statewide | Closure | | mdes.ms.gov |
| Platt Flooring Products | May 11, 2026 | June 11, 2026 | 86 | Houston, Chickasaw County | Closure | | mdes.ms.gov |
| Wheeler Fleet Solutions | April 30, 2026 | | 52 | Olive Branch, DeSoto County | Closure | | mdes.ms.gov |
| Services, Inc | April 17, 2026 | June 15, 2026 | 59 | Greenwood, Leflore County | Closure | | mdes.ms.gov |
| Greenwood Leflore Hospital | April 14, 2026 | | 425 | Greenwood, Leflore County | Closure | | mdes.ms.gov |
| Amplify Cell Technologies | March 31, 2026 | May 30, 2026 | 73 | Byhalia, Marshall County | Layoff | | mdes.ms.gov |
| Laboratory Corporation of America | March 17, 2026 | | 60 | Southaven, DeSoto County | Closure | | mdes.ms.gov |
| New Way Trucks | March 1, 2026 | May 30, 2026 | 86 | Booneville, Prentiss County | Layoff | | mdes.ms.gov |
| Stanley Black & Decker | February 20, 2026 | | 441 | Verona, Lee County | Closure | | mdes.ms.gov |
| Birdsong Peanuts- Aberdeen | February 13, 2026 | June 30, 2026 | 7 | Prairie, Monroe County | Layoff | | mdes.ms.gov |
| Regency Hospital | February 11, 2026 | | 102 | Meridian, Lauderdale County | Closure | | mdes.ms.gov |
| NIKE Retail Services, Inc | January 26, 2026 | | 193 | Byhalia, Marshall County | Layoff | | mdes.ms.gov |
| GXO Logistics | January 6, 2026 | | 220 | Southaven, DeSoto County | Closure | | mdes.ms.gov |
| Aberdeen (Monroe) | December 16, 2025 | | 99 | | Closure | | mdes.ms.gov |
| NOV Energy Products Services | December 1, 2025 | April 1, 2026 | 12 | Iuka, Tishomingo County | Closure | | mdes.ms.gov |
| Burgess-Norton Mfg. Co., Inc. Oxford (Lafayette) | November 6, 2025 | April 15, 2026 | 79 | | Closure | | mdes.ms.gov |
| Spectra Laboratories Southaven (DeSoto) | September 22, 2025 | | 155 | | Layoff | | mdes.ms.gov |
| Boyd Tunica, Inc./ Sam’s Town Hotel Gambling Hall – Robinsonville (Tunica) | September 4, 2025 | October 10, 2025 | 177 | | Closure | | mdes.ms.gov |
| Resolute Forest Products US Inc. / Domtar Grenada (Grenada) | August 21, 2025 | September 25, 2025 | 176 | | Layoff | | mdes.ms.gov |
| Advanced Distributor Products Grenada (Grenada) | August 13, 2025 | | 69 | | Layoff | | mdes.ms.gov |
| SIMOS Insourcing Solutions, LLC Olive Branch (DeSoto) | August 5, 2025 | October 3, 2025 | 159 | | Layoff | | mdes.ms.gov |
| Brookhaven, LLC Brookhaven (Lincoln) | July 11, 2025 | September 9, 2025 | 71 | | Layoff | | mdes.ms.gov |
| Finch Henry Job Corp Center/Education & Training Resources Batesville (Panola) | June 2, 2025 | June 11, 2025 | 113 | | Closure | | mdes.ms.gov |
| iQor Holding US LCC Meridian (Lauderdale) | May 31, 2025 | June 23, 2025 | 50 | | Layoff | | mdes.ms.gov |
| SSC Services for Education at JSU Jackson (Hinds) | April 29, 2025 | June 30, 2025 | 41 | | Layoff | | mdes.ms.gov |
| Pregis Innovative Packaging, LLC Tupelo (Lee) | April 3, 2025 | June 30, 2025 | 40 | | Closure | | mdes.ms.gov |
| C & D Jarnagin Co. Inc. Corinth (Alcorn) | April 2, 2025 | April 15, 2025 | 3 | | Closure | | mdes.ms.gov |
| IG Design Group Americas, Inc. Byhalia (Marshall) | March 27, 2025 | August 26, 2025 | 113 | | Closure | | mdes.ms.gov |
| NauticStar Boats Amory (Monroe) | March 18, 2025 | | 47 | | Closure | | mdes.ms.gov |
| Corinth (Alcorn) | March 18, 2025 | June 24, 2025 | 102 | | Layoff | | mdes.ms.gov |
| Services Americas, Inc. Canton (Madison) | February 18, 2025 | April 15, 2025 | 35 | | Layoff | | mdes.ms.gov |
| CAPSTONE Logistics Canton (Madison) | February 12, 2025 | April 14, 2025 | 65 | | Layoff | | mdes.ms.gov |
| Amory (Monroe) | February 6, 2025 | February 7, 2025 | 30 | | Closure | | mdes.ms.gov |
| Milwaukee Electric Tool Corp. Greenwood (Lefore) | January 29, 2025 | | Not listed | | Layoff | TBA. | mdes.ms.gov |
| Pontotoc (Pontotoc) | January 27, 2025 | | 121 | | Closure | | mdes.ms.gov |
| Distributors, Inc. Olive Branch (DeSoto) | January 22, 2025 | | 131 | | Closure | | mdes.ms.gov |
| Intuitive Surgical Southaven (DeSoto) | December 11, 2024 | | 157 | | Closure | | mdes.ms.gov |
| Solutions Vicksburg (Warren) | December 3, 2024 | | 80 | | Closure | | mdes.ms.gov |
| Levi Strauss & Co Canton (Madison) | October 17, 2024 | | 267 | | Closure | | mdes.ms.gov |
| View Operating Corporation Olive Branch (DeSoto) | October 3, 2024 | October 3, 2024 | 147 | | Layoff | | mdes.ms.gov |
| Laclede Chain Manufacturing Vicksburg (Warren) | September 19, 2024 | | 50 | | Closure | | mdes.ms.gov |
| YoungWilliams Clinton (Hinds) | September 3, 2024 | | 100 | | Layoff | | mdes.ms.gov |
| Inc. Gulfport (Harrison) | July 31, 2024 | | 54 | | Layoff | | mdes.ms.gov |
| Paxton Furniture Industries, LLC Okolona (Chickasaw) | July 23, 2024 | | 38 | | Closure | | mdes.ms.gov |
| Elior, Inc Ridgeland (Madison) | July 18, 2024 | | 59 | | Closure | | mdes.ms.gov |
| Agrisolutions Wear Technologies Corp. Holly Springs (Marshall) | February 20, 2024 | March 12, 2021 | 35 | | Closure | | mdes.ms.gov |
| Conair LLC Southaven (DeSoto) | February 8, 2024 | February 16, 2024 | 92 | | Closure | | mdes.ms.gov |
| Omega Motion Saltillo (Lee) | January 25, 2024 | March 19, 2024 | 130 | | Closure | | mdes.ms.gov |
| Homestead Furniture, LLC New Albany (Union) | January 18, 2024 | January 12, 2024 | 58 | | Layoff | | mdes.ms.gov |
| Crown Cork & Seal USA Inc. Batesville (Panola) | January 17, 2024 | February 12, 2024 | 145 | | Closure | | mdes.ms.gov |
| PSP Industries Iuka (Tishomingo) | | January 15, 2024 | 71 | | Layoff | | mdes.ms.gov |
| Plymouth Tube Company Eupora (Webster) | November 15, 2023 | November 18, 2023 | 77 | | Layoff | | mdes.ms.gov |
| FedEx Supply Chain Olive Branch (DeSoto) | October 31, 2023 | December 29, 2023 | 169 | | Closure | | mdes.ms.gov |
| Rollins Moving Storage, Inc. West Point ( Clay) | October 17, 2023 | October 26, 2023 | 21 | | Layoff | | mdes.ms.gov |
| Navistar Defense West Point (Clay) | October 16, 2023 | November 30, 2023 | 91 | | Layoff | | mdes.ms.gov |
| Navistar Defense West Point (Clay) | October 16, 2023 | October 26, 2023 | 118 | | Layoff | | mdes.ms.gov |
| Attala Steel, Inc. Kosciusko (Attala) | October 9, 2023 | October 5, 2023 | 83 | | Layoff | | mdes.ms.gov |
| Kuehne + Nagel, Inc. Southaven (DeSoto) | August 29, 2023 | August 31, 2023 | 110 | | Layoff | | mdes.ms.gov |
| Kuehne + Nagel, Inc. Southaven (DeSoto) | August 29, 2023 | August 31, 2023 | 110 | | Layoff | | mdes.ms.gov |
| YRC Worldwide (Yellow Corp.) Richland (Rankin) | August 3, 2023 | August 31, 2023 | 436 | | Closure | | mdes.ms.gov |
| YRC Worldwide (Yellow Corp.) Richland (Rankin) | August 3, 2023 | August 31, 2023 | 436 | | Closure | | mdes.ms.gov |
| International Converter Iuka (Tishomingo) | July 26, 2023 | August 8, 2023 | 38 | | Closure | | mdes.ms.gov |
| International Converter Iuka (Tishomingo) | July 26, 2023 | August 8, 2023 | 38 | | Closure | | mdes.ms.gov |
| Associated Wholesale Grocers Southaven (DeSoto) | July 25, 2023 | September 14, 2023 | 70 | | Closure | | mdes.ms.gov |
| Associated Wholesale Grocers Southaven (DeSoto) | July 25, 2023 | September 14, 2023 | 70 | | Closure | | mdes.ms.gov |
| Alan Ritchey, Inc. Southaven (DeSoto) | July 23, 2023 | September 13, 2023 | 191 | | Closure | | mdes.ms.gov |
| Alan Ritchey, Inc. Southaven (DeSoto) | July 23, 2023 | September 13, 2023 | 191 | | Closure | | mdes.ms.gov |
| Roseburg Forest Products Taylorsville (Smith) | June 21, 2023 | August 21, 2023 | 101 | | Closure | | mdes.ms.gov |
| Vectrus System Corporation/Keesler Base Services Biloxi (Harrison) | June 9, 2023 | | 191 | | Layoff | | mdes.ms.gov |
| Advanced Distributor Products Grenada (Grenada) | June 6, 2023 | | 38 | | Layoff | | mdes.ms.gov |
| Aerospace Corp DBA ASR- Pioneer Columbia (Marion) | May 31, 2023 | June 7, 2023 | 96 | | Closure | | mdes.ms.gov |
| Jimco Lamp and Manufacturing, LLC Southaven (DeSoto) | May 10, 2023 | | 53 | | Closure | | mdes.ms.gov |
| NauticStar Boats Amory (Monroe) | April 14, 2023 | April 14, 2023 | 92 | | Layoff | | mdes.ms.gov |
| Valeo Madison (Madison) | April 10, 2023 | April 19, 2023 | 20 | | Closure | | mdes.ms.gov |
| Advanced Distributor Products Grenada (Grenada) | April 7, 2023 | April 12, 2023 | 67 | | Layoff | | mdes.ms.gov |
| System Holly Springs (Marshall) | March 23, 2023 | March 27, 2023 | 100 | | Layoff | | mdes.ms.gov |
| Belmont (Tishomingo) | March 23, 2023 | March 27, 2023 | 50 | | Layoff | | mdes.ms.gov |
| Chain, Inc. Horn Lake (DeSoto) | March 20, 2023 | | 248 | | Closure | | mdes.ms.gov |
| Tiffin Motorhomes Belmont (Tishomingo) | March 6, 2023 | March 31, 2023 | 41 | | Layoff | | mdes.ms.gov |
| NCFI Polyurethane/Sleepmade Columbus (Lowndes) | March 1, 2023 | March 14, 2023 | 6 | | Layoff | | mdes.ms.gov |
| PSP Industries Fulton (Itawamba) | January 18, 2023 | January 13, 2024 | 36 | | Layoff | | mdes.ms.gov |
| Tri State Profile, LLC Iuka (Tishomingo) | January 9, 2023 | January 25, 2023 | 37 | | Layoff | | mdes.ms.gov |
| Motus Integrated Technologies Columbus (Lowndes) | January 3, 2023 | February 23, 2023 | 52 | | Closure | | mdes.ms.gov |
| Magnolia Processing DBA Pride of the Pond Tunica ( Tunica) | December 12, 2022 | December 6, 2022 | 57 | | Layoff | | mdes.ms.gov |
| United Furniture Amory (Monroe) | November 21, 2022 | November 21, 2022 | 1,000 | | Closure | | mdes.ms.gov |
| Tiffin Motorhomes Belmont (Tishomingo) | November 21, 2022 | December 1, 2022 | 50 | | Layoff | | mdes.ms.gov |
| Region One Mental Health Center Clarksdale (Coahoma) | November 14, 2022 | January 31, 2023 | 142 | | Closure | | mdes.ms.gov |
| GXO Logistics Supply Chain, Inc. Olive Branch (DeSoto) | November 7, 2022 | March 31, 2023 | 165 | | Closure | | mdes.ms.gov |
| Greenwood Leflore Hospital Greenwood, (Leflore) | October 5, 2022 | | 600 | | Layoff | | mdes.ms.gov |
| New Dairy Alabama, LLC Hattiesburg (Forrest) | | October 2, 2022 | 236 | | Closure | | mdes.ms.gov |
| Aluminum Extrusions, Inc. (AEI) Senatobia (Tate) | September 29, 2022 | September 20, 2022 | 6 | | Closure | | mdes.ms.gov |
| Tiffin Motorhomes Belmont (Tishomingo) | September 15, 2022 | September 2, 2022 | 25 | | Layoff | | mdes.ms.gov |
| VanLeigh RV Burnsville (Tishomingo) | September 6, 2022 | September 22, 2022 | 43 | | Layoff | | mdes.ms.gov |
| Corsicana Mattress Company Olive Branch (DeSoto) | August 29, 2022 | | 52 | | Closure | | mdes.ms.gov |
| Kindthread/Landau Uniforms Olive Branch (DeSoto) | August 18, 2022 | September 20, 2022 | 75 | | Closure | | mdes.ms.gov |
| Emilia DeKalb (Kemper) | August 17, 2022 | August 25, 2022 | 90 | | Closure | | mdes.ms.gov |
| Tyson Foods Vicksburg (Warren) | August 16, 2022 | | 60 | | Layoff | | mdes.ms.gov |
| Hood Industries Beaumont (Perry) | August 9, 2022 | August 26, 2022 | 223 | | Closure | | mdes.ms.gov |
| NewCo3 Batesville (Panola) | August 8, 2022 | | 19 | | Closure | | mdes.ms.gov |
| Jefferson County Hospital Fayette (Jefferson) | July 25, 2022 | August 1, 2022 | 8 | | Layoff | | mdes.ms.gov |
| McKesson Corporation – South Jackson Richland (Rankin) | July 1, 2022 | July 29, 2022 | 26 | | Closure | | mdes.ms.gov |
| McKesson Corporation – Jackson Ridgeland (Madison) | July 1, 2022 | | 31 | | Layoff | | mdes.ms.gov |
| La-Z-Boy South Newton (Newton) | July 1, 2022 | August 24, 2022 | 178 | | Closure | | mdes.ms.gov |
| United Furniture Industries Amory (Monroe) | June 30, 2022 | July 27, 2022 | 171 | | Layoff | | mdes.ms.gov |
| Southern Motion Pontotoc (Pontotoc) | June 20, 2022 | | 86 | | Layoff | | mdes.ms.gov |
| Fusion Ecru (Pontotoc) | June 20, 2022 | | 55 | | Layoff | | mdes.ms.gov |
| FXI, Inc. Coldwater (Tate) | June 13, 2022 | | 100 | | Layoff | | mdes.ms.gov |
| Federal Express Corporation Richland (Rankin) | June 8, 2022 | September 4, 2023 | 77 | | Closure | | mdes.ms.gov |
| Sears Waynesboro (Wayne) | June 1, 2022 | | 4 | | Closure | | mdes.ms.gov |
| Armstrong Flooring Jackson (Hinds) | May 23, 2022 | July 27, 2022 | 109 | | Closure | | mdes.ms.gov |
| NFI – National Freight Incorporated Meridian (Lauderdale) | January 14, 2022 | March 17, 2022 | 91 | | Closure | | mdes.ms.gov |
| Express Grain Terminals, LLC. Greenwood (Leflore) | January 10, 2022 | January 28, 2022 | 128 | | Closure | | mdes.ms.gov |
| Five Below, Inc. Olive Branch (DeSoto) | January 6, 2022 | | 69 | | Closure | | mdes.ms.gov |
| MAP of Easton, Inc. Clarksdale (Coahoma) | December 10, 2021 | December 31, 2021 | 50 | | Closure | | mdes.ms.gov |
| Culpepper & Associates Security Services, Inc. Biloxi (Harrison) | November 23, 2021 | November 23, 2021 | 16 | | Layoff | | mdes.ms.gov |
| Anthem, Inc./ Beacon Health Options Hernando (Desoto) | September 21, 2021 | December 31, 2021 | 4 | | Layoff | | mdes.ms.gov |
| Vantec Hitachi Transport System Canton (Madison) | May 5, 2021 | June 30, 2021 | 337 | | Closure | | mdes.ms.gov |
| United Financial, Inc. Tupelo (Lee) | April 23, 2021 | April 22, 2021 | 6 | | Layoff | | mdes.ms.gov |
| Montgomery Enterprises, Inc./Cash Title Exchange Tupelo (Lee) | April 23, 2021 | April 22, 2021 | 6 | | Layoff | | mdes.ms.gov |
| Mississippi Lending Services Tupelo (Lee) | April 23, 2021 | April 22, 2021 | 6 | | Layoff | | mdes.ms.gov |
| Ryder – McCormick and Company, Inc. Byhalia (Marshall) | March 29, 2021 | June 1, 2021 | 60 | | Closure | | mdes.ms.gov |
| Saks Fifth Avenue | March 11, 2021 | May 17, 2021 | 114 | | Layoff | | mdes.ms.gov |
| Kline Mechanical System, Inc. Fulton (Itawamba) | March 9, 2021 | February 15, 2021 | 42 | | Layoff | | mdes.ms.gov |
| Marelli Cabin Comfort USA, Inc. Madison (Madison) | March 2, 2021 | April 13, 2021 | 68 | | Closure | | mdes.ms.gov |
| AbilityWorks Oxford (Lafayette) | March 1, 2021 | February 13, 2021 | 8 | | Layoff | | mdes.ms.gov |
| Purple Banana – McKenzie PB, LLC Bay St. Louis (Hancock) | February 2, 2021 | January 31, 2021 | 8 | | Closure | | mdes.ms.gov |
| Genlyte Thomas Group ,LLC/Signify Tupelo (Lee) | January 19, 2021 | April 7, 2021 | 105 | | Closure | | mdes.ms.gov |
| Scotch Plywood Company Waynesboro (Wayne) | January 12, 2021 | January 13, 2021 | 74 | | Layoff | | mdes.ms.gov |
| Peco Foods, Inc. Canton (Noxubee) | January 8, 2021 | April 2, 2021 | 235 | | Closure | | mdes.ms.gov |
| Peco Foods, Inc. Canton (Madison) | January 8, 2021 | March 26, 2021 | 434 | | Closure | | mdes.ms.gov |
| Anderson Technologies South, LLC Batesville (Panola) | December 18, 2020 | December 18, 2020 | 20 | | Layoff | | mdes.ms.gov |
| Neovia Logistics Services, LLC Southaven (DeSoto) | December 16, 2020 | January 31, 2021 | 80 | | Layoff | | mdes.ms.gov |
| Dynamic Aviation OSRG Base Kiln (Hancock) | October 31, 2020 | December 31, 2020 | 3 | | Closure | | mdes.ms.gov |
| P.F. Chang’s China Bistro Ridgeland (Madison) | September 18, 2020 | March 29, 2020 | 75 | | Layoff | | mdes.ms.gov |
| The Services System Robinson (Tunica) | September 14, 2020 | November 14, 2020 | 139 | | Closure | | mdes.ms.gov |
| Avis Budget Group Pearl (Rankin) | August 28, 2020 | June 1, 2020 | 3 | | Layoff | | mdes.ms.gov |
| Stein Mart Madison (Madison) | August 24, 2020 | October 5, 2020 | 16 | | Closure | | mdes.ms.gov |
| Ulmer/Stride Rite Shoes Jackson (Hinds) | August 13, 2020 | August 31, 2020 | 3 | | Closure | | mdes.ms.gov |
| Cooper Lighting Solutions Vicksburg (Warren) | August 7, 2020 | October 15, 2020 | 300 | | Closure | | mdes.ms.gov |
| The MS. Department of Corrections – MHM Health Professionals, LLC Jackson (Hinds) | August 6, 2020 | | 373 | | Layoff | | mdes.ms.gov |
| Hederman Brothers Printers Pearl (Rankin) | July 30, 2020 | July 30, 2020 | 10 | | Layoff | | mdes.ms.gov |
| American Queen Steam Boat Company- Natchez New Albany (Indiana) | July 24, 2020 | September 24, 2020 | 17 | | Layoff | | mdes.ms.gov |
| Hollywood Casino Gulf Coast Bay St. Louis (Hancock) | July 15, 2020 | September 15, 2020 | 15 | | Layoff | | mdes.ms.gov |
| Boomtown Casino Biloxi Biloxi (Harrison) | July 15, 2020 | September 15, 2020 | 23 | | Layoff | | mdes.ms.gov |
| Hollywood Casino, Tunica Robinsonville (Tunica) | July 13, 2020 | June 11, 2020 | 153 | | Layoff | | mdes.ms.gov |
| 1st Jackpot Casino, Tunica Robinsonville (Tunica) | July 13, 2020 | June 11, 2020 | 67 | | Layoff | | mdes.ms.gov |
| Emerald Home New Albany (Union) | July 9, 2020 | September 8, 2020 | 9 | | Closure | | mdes.ms.gov |
| Thrive South, LLC Pearl (Rankin) | March 18, 2020 | March 18, 2020 | 1 | | Layoff | | mdes.ms.gov |
| Milwaukee Tool Clinton (Hinds) | February 13, 2013 | March 30, 2023 | 150 | | Closure | | mdes.ms.gov |