Data / Hiring / Massachusetts / Karyopharm Therapeutics Inc.
Karyopharm Therapeutics Inc. in Newton, MA: 32 certified H-1B and PERM cases, FY2023 to FY2026
Karyopharm Therapeutics Inc., Newton, MA, had 32 certified H-1B and PERM cases in Department of Labor disclosure data, decided from October 12, 2022 to April 21, 2026: 24 H-1B labor condition applications and 8 PERM labor certifications. Its most frequent role is Senior Manager, Regulatory Operations in Newton, MA, at a median offered wage of $136,324 a year.
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- 26-3931704Employer ID (FEIN)
- Newton, MAAddress
- 32Certified cases
- 32Positions requested
- 2Denied or withdrawn
Certified cases by fiscal year
Fiscal years run from October 1 to September 30. The latest year covers decisions through April 21, 2026.
| Fiscal year | H-1B | PERM | Positions | Median offered wage |
|---|---|---|---|---|
| FY2023 | 10 | 0 | 10 | $136,882 |
| FY2024 | 2 | 6 | 8 | $142,716 |
| FY2025 | 8 | 0 | 8 | $132,687 |
| FY2026 | 4 | 2 | 6 | $170,990 |
Roles certified
Cases with the same job title, occupation code and worksite are grouped. Offered wage is the wage the employer filed; the range leaves out the lowest and highest 5% when a group has 20 cases or more. The prevailing wage is the one the employer filed against. A blank worksite means the file does not give one.
| Job title | Occupation | Worksite | Cases | Years | Median offered | Offered range | Median prevailing | Wage level | Program | Latest decision | Latest case number | Source |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Senior Manager, Regulatory Operations | 11-9199 Regulatory Affairs Managers | Newton, MA | 4 | FY2023 to FY2026 | $179,250 | $160,685 to $190,215 | $168,896 | III | H-1B | March 27, 2026 | I-200-26079-719694 | dol.gov |
| Senior Clinical Data Manager | 15-2051 Clinical Data Managers | Farmington, AR | 2 | FY2024 to FY2025 | $128,578 | $124,500 to $132,657 | $122,076 | IV | H-1B | September 24, 2025 | I-200-25260-315964 | dol.gov |
| Senior Manager, Regulatory Operations | Newton, MA | 2 | FY2024 | $165,342 | $160,685 to $170,000 | Not listed | PERM | September 18, 2024 | G-100-23178-147400 | dol.gov | ||
| Sr Scientist, Analytical Chemistry | 19-2031 Chemists | Newton, MA | 2 | FY2023 to FY2026 | $148,622 | $143,763 to $153,480 | $140,629 | IV | H-1B | November 19, 2025 | I-200-25316-401122 | dol.gov |
| ="Senior Biostatistician" | Statisticians | Newton, MA | 1 | FY2025 | $187,044 | $187,044 to $187,044 | $100,506 | IV | H-1B | January 16, 2025 | I-200-25009-606996 | dol.gov |
| Associate Director, IST Operations | 19-1029 Biologists | Edgewater, NJ | 1 | FY2024 | $124,747 | $124,747 to $124,747 | $120,349 | IV | H-1B | August 16, 2024 | I-200-23090-892502 | dol.gov |
| Associate Director, Regulatory Operations | 11-9199 Regulatory Affairs Managers | Newton, MA | 1 | FY2026 | $188,500 | $188,500 to $188,500 | $187,616 | III | H-1B | March 27, 2026 | I-200-26079-719715 | dol.gov |
| Associate Director, XPOVIO U.S. Multiple Myeloma Marketing | 11-2021 Marketing Managers | Newton, MA | 1 | FY2023 | $169,000 | $169,000 to $169,000 | $154,960 | III | H-1B | January 31, 2023 | I-200-21351-773227 | dol.gov |
| Clinical Data Manager | Newton, MA | 1 | FY2024 | $120,000 | $120,000 to $120,000 | Not listed | PERM | September 18, 2024 | G-100-23163-099920 | dol.gov | ||
| Clinical Trial Manager | 11-9121 Natural Sciences Managers | 1 | FY2024 | $208,000 | $208,000 to $208,000 | $208,000 | Level I | PERM | June 4, 2024 | A-23143-46203 | dol.gov | |
| GCP Documentation Specialist | 15-1299 Document Management Specialists | Newton, MA | 1 | FY2025 | $96,616 | $96,616 to $96,616 | $96,616 | II | H-1B | April 22, 2025 | I-200-25105-866369 | dol.gov |
| Manager Regulatory Operations | 13-1041 Regulatory Affairs Specialists | Newton, MA | 1 | FY2023 | $109,745 | $109,745 to $109,745 | $103,875 | IV | H-1B | April 6, 2023 | I-200-23089-890084 | dol.gov |
| Manager, Regulatory Affairs | 11-9199 Regulatory Affairs Managers | Newton, MA | 1 | FY2023 | $120,000 | $120,000 to $120,000 | $111,904 | II | H-1B | November 1, 2022 | I-200-22049-913378 | dol.gov |
| Manager, Regulatory Operations | 13-1041 Regulatory Affairs Specialists | Morrisville, NC | 1 | FY2025 | $139,932 | $139,932 to $139,932 | $92,227 | IV | H-1B | July 16, 2025 | I-200-25190-161262 | dol.gov |
| Manager, Regulatory Operations | 13-1041 Regulatory Affairs Specialists | Des Plaines, IL | 1 | FY2023 | $130,000 | $130,000 to $130,000 | $94,827 | IV | H-1B | April 21, 2023 | I-200-23104-934396 | dol.gov |
| Pharmacovigilance Specialist | 17-2111 Health and Safety Engineers, Except Mining Safety Engineers and Inspectors | Newton, MA | 1 | FY2023 | $110,000 | $110,000 to $110,000 | $101,088 | III | H-1B | October 12, 2022 | I-200-20051-339555 | dol.gov |
| Senior Associate, Regulatory Operations | 13-1041 Regulatory Affairs Specialists | Newton, MA | 1 | FY2026 | $130,000 | $130,000 to $130,000 | Not listed | PERM | April 21, 2026 | G-100-24361-571802 | dol.gov | |
| Senior Clinical Data Manager | 15-2051 Data Scientists | 1 | FY2024 | $120,000 | $120,000 to $120,000 | $112,382 | Level III | PERM | June 4, 2024 | A-23143-46524 | dol.gov | |
| Senior Clinical Data Manager | 15-2051 Clinical Data Managers | Apex, NC | 1 | FY2023 | $120,000 | $120,000 to $120,000 | $115,669 | III | H-1B | January 12, 2023 | I-200-23005-683715 | dol.gov |
| Senior Statistical Programmer 1 | 15-2041 Biostatisticians | Newton, MA | 1 | FY2025 | $123,966 | $123,966 to $123,966 | $106,600 | III | H-1B | April 28, 2025 | I-200-25111-886404 | dol.gov |
| Senior TMF Specialist | 15-1299 Document Management Specialists | Newton, MA | 1 | FY2026 | $86,781 | $86,781 to $86,781 | Not listed | PERM | March 3, 2026 | G-100-24295-419996 | dol.gov | |
| Senior VP, Regulatory Affairs | 11-9199 Managers, All Other | 1 | FY2024 | $350,000 | $350,000 to $350,000 | $180,294 | Level IV | PERM | June 6, 2024 | A-23061-07530 | dol.gov | |
| Sr Clinical Data Manager | 15-2051 Clinical Data Managers | Centerville, VA | 1 | FY2025 | $120,000 | $120,000 to $120,000 | $100,235 | II | H-1B | June 4, 2025 | I-200-22284-523514 | dol.gov |
| Sr Clinical Data Manager | 15-2051 Clinical Data Managers | Haymarket, VA | 1 | FY2025 | $132,717 | $132,717 to $132,717 | $110,739 | II | H-1B | April 23, 2025 | I-200-25107-873684 | dol.gov |
| Sr Scientist Bioanalytical | 19-1021 Biochemists and Biophysicists | Newton, MA | 1 | FY2023 | $145,000 | $145,000 to $145,000 | $135,990 | IV | H-1B | August 1, 2023 | I-200-22112-096993 | dol.gov |
| Sr. Clinical Trial Manager | 13-1082 Project Management Specialists | Newton, MA | 1 | FY2025 | $160,000 | $160,000 to $160,000 | $128,627 | IV | H-1B | May 6, 2025 | I-200-23202-205948 | dol.gov |
Worksite states
| State | Cases |
|---|---|
| Massachusetts | 21 |
| Arkansas | 2 |
| North Carolina | 2 |
| Virginia | 2 |
| New Jersey | 1 |
| Illinois | 1 |
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Updated April 21, 2026. Read from US Department of Labor, Office of Foreign Labor Certification. Public domain (U.S. government work). A certified labor condition application (H-1B, H-1B1, E-3) or PERM labor certification is an employer filing the Department of Labor approved. It is not a count of people hired or visas issued. Wages are as the employer filed them, converted to a yearly figure at 2,080 hours; a wage whose unit is missing is left blank. The files show the first worksite of a case. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.