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Data / Hiring / California / Denali Therapeutics Inc.

Denali Therapeutics Inc. in South San Francisco, CA: 42 certified H-1B and PERM cases, FY2023 to FY2026

Denali Therapeutics Inc., South San Francisco, CA, had 42 certified H-1B and PERM cases in Department of Labor disclosure data, decided from October 27, 2022 to June 29, 2026: 37 H-1B labor condition applications and 5 PERM labor certifications. Its most frequent role is Director, Clinical Operations in South San Francisco, CA, at a median offered wage of $141,221 a year.

SpecStream is the live web data engine for teams and agents. It reads the Department of Labor's H-1B and PERM disclosure files and keeps each employer's filings by role, place and wage. Ask for your own cut (a role, a state, a list of companies) and new filings arrive in your sheet, CRM, Slack or agent.

Employer ID (FEIN)
46-3872213
Address
South San Francisco, CA
Certified cases
42
Positions requested
42
Denied or withdrawn
5

Certified cases by fiscal year

Fiscal years run from October 1 to September 30. The latest year covers decisions through June 29, 2026.

Fiscal yearH-1BPERMPositionsMedian offered wage
FY2023718$146,242
FY202413215$128,939
FY202511011$158,000
FY2026628$148,175

Roles certified

Cases with the same job title, occupation code and worksite are grouped. Offered wage is the wage the employer filed; the range leaves out the lowest and highest 5% when a group has 20 cases or more. The prevailing wage is the one the employer filed against. A blank worksite means the file does not give one.

Job titleOccupationWorksiteCasesYearsMedian offeredOffered rangeMedian prevailingWage levelProgramLatest decisionLatest case numberSource
Director, Clinical Operations11-9121 Natural Sciences ManagersSouth San Francisco, CA2FY2023 to FY2025$218,000$209,000 to $251,000$209,841IIH-1BMay 28, 2025I-200-25140-995405dol.gov
Scientist19-1042 Medical Scientists, Except EpidemiologistsSouth San Francisco, CA2FY2024$162,782$123,000 to $226,722$125,965IIIH-1BMay 2, 2024I-200-23137-032269dol.gov
Scientist, Discovery Pharmacology19-1042 Medical Scientists, Except EpidemiologistsSouth San Francisco, CA2FY2023 to FY2025$123,259$123,000 to $158,000$109,366IIH-1BMay 28, 2025I-200-25140-995385dol.gov
Senior Scientist, Large Molecule Formulation Development19-1021 Biochemists and BiophysicistsSouth San Francisco, CA2FY2024 to FY2026$140,000$138,000 to $174,333$126,214IIH-1BNovember 6, 2025I-200-25272-341782dol.gov
="Associate Scientist, Discovery Pharmacology"Biochemists and BiophysicistsSouth San Francisco, CA1FY2025$122,166$122,166 to $126,667$112,882IIH-1BJanuary 13, 2025I-200-25003-592944dol.gov
="Senior Scientist, Discovery Biology"Biochemists and BiophysicistsSouth San Francisco, CA1FY2025$142,000$142,000 to $174,333$137,072IIIH-1BJanuary 16, 2025I-200-25008-605434dol.gov
Associate Data Engineer15-2051 Data ScientistsSouth San Francisco, CA1FY2025$119,500$119,500 to $137,000$116,646IIH-1BOctober 1, 2024I-200-23265-370060dol.gov
Associate Director, Clinical Data Management15-2051 Clinical Data ManagersSouth San Francisco, CA1FY2026$204,000$204,000 to $210,000Not listedPERMJune 29, 2026G-100-25155-050159dol.gov
Associate Director, Clinical Data Management15-2051 Clinical Data ManagersHolly Springs, NC1FY2025$204,194$204,194 to $211,500$137,696IVH-1BAugust 20, 2025I-200-25225-240286dol.gov
Associate Director, Enterprise Data Architect15-1243 Database ArchitectsSouth San Francisco, CA1FY2025$174,000$174,000 to $215,000$170,893IIIH-1BDecember 30, 2024I-200-24354-559077dol.gov
Associate Scientist, In Vivo19-1029 Biological Scientists, All OtherSouth San Francisco, CA1FY2024$101,816$101,816 to $126,700$101,816IIH-1BMay 20, 2024I-200-24134-989765dol.gov
Biostatistician15-2041 Biotatisticians1FY2023$155,000$155,000 to $155,000$78,936Level IPERMDecember 27, 2022A-22104-40766dol.gov
Clinical Data Manager15-2051 Clinical Data ManagersSouth San Francisco, CA1FY2023$179,878$179,878 to $185,801$179,878IVH-1BDecember 16, 2022I-200-22343-631839dol.gov
Director, Learning & Organizational Development11-3131 Training and Development ManagersSouth San Francisco, CA1FY2024$220,000$220,000 to $243,285$198,723IVH-1BMay 2, 2024I-200-22189-340837dol.gov
Manager, Clinical Data Management15-2051 Clinical Data ManagersSouth San Francisco, CA1FY2026$186,846$186,846 to $186,846Not listedPERMNovember 14, 2025G-100-24184-169511dol.gov
Medical Director, Global Drug Safety11-9121 Natural Sciences ManagersSouth San Francisco, CA1FY2025$265,000$265,000 to $291,333$233,210IIIH-1BOctober 22, 2024I-200-24218-245340dol.gov
Postdoctoral Scientist19-1029 Molecular and Cellular BiologistsSouth San Francisco, CA1FY2024$75,000$75,000 to $80,000$66,269IH-1BOctober 20, 2023I-200-22136-177191dol.gov
Principal Scientist, Translational Medicine19-1042 Medical Scientists, Except EpidemiologistsSouth San Francisco, CA1FY2025$165,333$165,333 to $204,000$160,826IVH-1BApril 18, 2025I-200-25101-856143dol.gov
Program Director11-9121 Natural Sciences Managers1FY2024$208,322$208,322 to $208,322$176,030Level IIPERMJanuary 2, 2024A-22299-46454dol.gov
Program Director11-9121 Natural Sciences ManagersSouth San Francisco, CA1FY2024$223,034$223,034 to $238,260$154,872H-1BMarch 21, 2024I-200-24074-800723dol.gov
Quality Assurance Specialist19-1022 MicrobiologistsSalt Lake City, UT1FY2026$100,000$100,000 to $107,000$86,549IIIH-1BDecember 16, 2025I-200-25343-467711dol.gov
Research Scientist19-1042 Medical Scientists, Except Epidemiologists1FY2024$116,000$116,000 to $116,000$89,606Level IPERMFebruary 6, 2024A-22301-47993dol.gov
Research Scientist19-1042 Medical Scientists, Except EpidemiologistsSouth San Francisco, CA1FY2023$86,220$86,220 to $96,984$76,814IH-1BAugust 30, 2023I-200-21139-327903dol.gov
Scientist19-1029 Molecular and Cellular BiologistsSouth San Francisco, CA1FY2024$109,438$109,438 to $116,483$86,424IIH-1BMay 2, 2024I-200-22245-454099dol.gov
Scientist19-1021 Biochemists and BiophysicistsSouth San Francisco, CA1FY2023$128,752$128,752 to $152,672$128,752IIIH-1BJuly 28, 2023I-203-21356-783049dol.gov
Scientist, Bioanalysis19-2031 ChemistsSouth San Francisco, CA1FY2024$128,939$128,939 to $153,000$128,939IIIH-1BAugust 8, 2024I-200-24214-239570dol.gov
Scientist, Protein Mass Spect. & Analytical Development19-2031 ChemistsSouth San Francisco, CA1FY2024$123,614$123,614 to $136,000$123,614IVH-1BOctober 20, 2023I-200-22136-177177dol.gov
Scientist, Protein Purification and Characterization19-2031 ChemistsSouth San Francisco, CA1FY2024$109,438$109,438 to $116,483$84,282IIH-1BJuly 16, 2024I-200-22245-454093dol.gov
Scientist, Purification Process Development19-1021 Biochemists and BiophysicistsSouth San Francisco, CA1FY2026$149,350$149,350 to $149,350$115,357IIH-1BMay 4, 2026I-200-26117-839151dol.gov
Scientist, Quantitative Pharmacology19-1029 Bioinformatics ScientistsSouth San Francisco, CA1FY2024$140,000$140,000 to $171,667$101,816IIH-1BJune 12, 2024I-200-24157-076715dol.gov
Scientist, iPSC Discovery Biology19-1021 Biochemists and BiophysicistsSouth San Francisco, CA1FY2025$121,000$121,000 to $153,000$112,882IIH-1BMay 28, 2025I-200-25140-995432dol.gov
Senior Controls Engineer17-2199 Mechatronics EngineersSalt Lake City, UT1FY2026$147,000$147,000 to $147,000$125,632IVH-1BApril 16, 2026I-200-26099-775874dol.gov
Senior Engineer, Cybersecurity15-1299 Information Security EngineersSouth San Francisco, CA1FY2023$140,442$140,442 to $174,000$131,685IIIH-1BMarch 3, 2023I-200-23055-802773dol.gov
Senior Manager, Cybersecurity15-1299 Information Security EngineersSouth San Francisco, CA1FY2026$167,000$167,000 to $211,000$114,795IIH-1BNovember 24, 2025I-200-25321-414689dol.gov
Senior Manufacturing Sciences and Technology Engineer17-2031 Bioengineers and Biomedical EngineersSalt Lake City, UT1FY2024$130,000$130,000 to $160,000$111,696IVH-1BJuly 25, 2024I-200-24200-205455dol.gov
Senior Scientist, Cell Process Development19-1021 Biochemists and BiophysicistsSouth San Francisco, CA1FY2026$138,000$138,000 to $181,000$115,357IIH-1BFebruary 2, 2026I-200-25310-383185dol.gov
Senior Scientist, Data15-2051 Data ScientistsSouth San Francisco, CA1FY2025$158,000$158,000 to $178,000$128,398IIH-1BMay 28, 2025I-200-25140-995480dol.gov
Senior Scientist, Tech Op19-1021 Biochemists and BiophysicistsSouth San Francisco, CA1FY2023$152,041$152,041 to $170,000$130,437IIIH-1BAugust 18, 2023I-200-23223-257937dol.gov

Worksite states

Also on SpecStream

Updated June 29, 2026. Read from US Department of Labor, Office of Foreign Labor Certification. Public domain (U.S. government work). A certified labor condition application (H-1B, H-1B1, E-3) or PERM labor certification is an employer filing the Department of Labor approved. It is not a count of people hired or visas issued. Wages are as the employer filed them, converted to a yearly figure at 2,080 hours; a wage whose unit is missing is left blank. The files show the first worksite of a case. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.