Data / Federal rules / 2024-29583

Possession, Use, and Transfer of Select Agents and Toxins; Biennial Review of the List of Select Agents and Toxins

The Health and Human Services Department published this final rule in the Federal Register on December 17, 2024. It took effect on January 16, 2025.

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What the agency says

This rule finalizes updates to the HHS list of select agents and toxins that could pose a severe threat to public health and safety. These updates were proposed along with other changes to the select agent and toxin regulations, which will be addressed in a separate regulatory action. In a companion document published in this issue of the Federal Register, the U.S. Department of Agriculture (USDA) is making parallel regulatory changes.

Key facts

Document number: 2024-29583
Type: Final rule
Action: Final rule
Agency: Health and Human Services Department
Published: December 17, 2024
Takes effect: January 16, 2025
Dates: This final rule is effective January 16, 2025.
Docket: Docket No. CDC-2020-0024
Regulation ID (RIN): 0920-AA71
Code of Federal Regulations: 42 CFR 73
Topics: Biologics; Packaging and containers; Penalties; Reporting and recordkeeping requirements; Transportation
Significant: Yes, under Executive Order 12866
Pages: 12

The document on federalregister.gov PDF

Other documents from the Health and Human Services Department

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Action Levels for Cadmium in Processed Food Intended for Babies and Young Children; Draft Guidance for Industry; Availability 2026-21670	Proposed rule	Oct 23
Hazard Analysis and Risk-Based Preventive Controls for Human Food; Draft Guidance for Industry; Availability 2026-21669	Proposed rule	Oct 23
Medicare Program; Implementation of Sections 6219, 6220, and 6224 of the Consolidated Appropriations Act, 2026 2026-21420	Proposed rule	Oct 20
Further Reducing Bureaucracy and Burden From the Administration for Native Americans 2026-21004	Proposed rule	Oct 14
Food Additives Permitted in Feed and Drinking Water of Animals; Chromium Propionate 2026-20979	Final rule	Oct 14
Use of Salt Substitutes To Reduce the Sodium Content in Standardized Foods 2026-20848 · significant	Final rule	Oct 13
Medical Devices; Immunology and Microbiology Devices; Classification of the System for Detection of Nucleic Acid From Non-Viral Microorganism(s) Causing Sexually Transmitted Infections Using Home-Collected Specimens 2026-20727	Final rule	Oct 9
Medical Devices; Cardiovascular Devices; Classification of the Infant Pulse Rate and Oxygen Saturation Monitor for Over-the-Counter Use 2026-20726	Final rule	Oct 9

Everything from the Health and Human Services Department · Rules on biologics · Rules on packaging and containers · Rules on penalties · Published in December 2024

Read from the Federal Register API, last updated 2026-10-23. The document on federalregister.gov is the official record; dates and dockets can change through later corrections. Free to reuse with credit to SpecStream under CC BY 4.0.