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Data / Federal rules / 2025-23702

Global Benchmark for Efficient Drug Pricing (GLOBE) Model

The Centers for Medicare & Medicaid Services published this proposed rule in the Federal Register on December 23, 2025. Comments closed on February 23, 2026.

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What the agency says

This proposed rule proposes to implement the Global Benchmark for Efficient Drug Pricing Model ("GLOBE Model"), a new Medicare payment model under section 1115A of the Social Security Act (the Act). The GLOBE Model would test whether a payment model that uses an alternative method for calculating Part B inflation rebate amounts for certain separately payable Part B drugs and biologicals products reduces costs for Medicare fee-for-service (FFS) beneficiaries and the Medicare program while preserving quality of care.

Key facts

Document number
2025-23702
Type
Proposed rule
Action
Proposed rule
Agency
Health and Human Services Department; Centers for Medicare & Medicaid Services
Published
December 23, 2025
Comments due
February 23, 2026
Dates
To be assured consideration, comments must be received at one of the addresses provided below, by February 23, 2026.
Docket
CMS-5545-P
Regulation ID (RIN)
0938-AV66
Code of Federal Regulations
42 CFR 513
Topics
Administrative practice and procedure; Health facilities; Medicare; Reporting and recordkeeping requirements
Significant
Yes, under Executive Order 12866
Pages
93

The document on federalregister.gov PDF

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Everything from the Centers for Medicare & Medicaid Services · Rules on administrative practice and procedure · Rules on health facilities · Rules on medicare · Published in December 2025

Read from the Federal Register API, last updated 2026-10-24. The document on federalregister.gov is the official record; dates and dockets can change through later corrections. Free to reuse with credit to SpecStream under CC BY 4.0.