Data / Drug companies / Tricyclic Antidepressant
Tricyclic Antidepressant drugs: 21 drugs from 89 companies in the FDA NDC directory
Tricyclic Antidepressant is an FDA established pharmacologic class. The FDA National Drug Code Directory lists 668 products in this class from 89 companies, covering 21 drugs by generic name. The main marketing category is generic drugs (ANDA), and the newest product started marketing on October 29, 2026.
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- 89Companies
- 668Products
- 21Drugs by generic name
Drugs in the Tricyclic Antidepressant class
Ranked by number of companies that list the drug.
| Drug | Products here | Companies listing it |
|---|---|---|
| Doxepin hydrochloride | 183 | 45 |
| Amitriptyline hydrochloride | 204 | 35 |
| Nortriptyline hydrochloride | 82 | 29 |
| Clomipramine hydrochloride | 48 | 17 |
| Imipramine hydrochloride | 31 | 14 |
| Desipramine hydrochloride | 38 | 8 |
| Doxepin | 18 | 8 |
| Imipramine pamoate | 9 | 3 |
| Amitriptyline hcl | 8 | 2 |
| Amoxapine | 8 | 2 |
| Trimipramine maleate | 6 | 2 |
| Protriptyline hydrochloride | 4 | 2 |
| Desipramine | 6 | 1 |
| Doxepin hcl | 5 | 1 |
| Perphenazine and amitriptyline hydrochloride | 5 | 1 |
| Clomipramine hydrochloride capsules | 3 | 1 |
| Nortriptyline hcl | 3 | 1 |
| Trimipramine | 3 | 1 |
| Chlordiazepoxide and amitriptyline hydrochloride | 2 | 1 |
| Desipramine hcl | 1 | 1 |
| Doxepn hydrochloride | 1 | 1 |
Companies with the most products in this class
| Company | Products | Main dosage forms | Main marketing category | Newest product started |
|---|---|---|---|---|
| Bryant Ranch Prepack | 43 | capsule; tablet, film coated | Generic drugs (ANDA) | November 1, 2025 |
| Remedyrepack Inc. | 32 | capsule; tablet | Generic drugs (ANDA) | September 25, 2026 |
| A-S Medication Solutions | 28 | tablet, film coated; capsule | Generic drugs (ANDA) | November 1, 2025 |
| Direct_Rx | 17 | capsule; tablet, film coated | Generic drugs (ANDA) | July 22, 2025 |
| Aurobindo Pharma Limited | 15 | capsule; tablet, film coated | Generic drugs (ANDA) | March 20, 2026 |
| Chartwell RX, LLC | 15 | tablet; capsule | Generic drugs (ANDA) | September 4, 2020 |
| Mylan Pharmaceuticals Inc. | 15 | tablet, film coated; capsule | Generic drugs (ANDA) | January 4, 2019 |
| Advanced Rx of Tennessee, LLC | 14 | tablet, film coated; capsule | Generic drugs (ANDA) | June 3, 2025 |
| Alembic Pharmaceuticals Inc. | 14 | capsule; tablet, film coated | Generic drugs (ANDA) | August 5, 2021 |
| Alembic Pharmaceuticals Limited | 14 | capsule; tablet, film coated | Generic drugs (ANDA) | August 5, 2021 |
| Lifestar Pharma LLC | 14 | capsule; tablet, film coated | Generic drugs (ANDA) | February 10, 2022 |
| Coupler LLC | 13 | tablet, film coated; capsule | Generic drugs (ANDA) | August 21, 2026 |
| Golden State Medical Supply, Inc. | 13 | tablet, film coated; tablet | Generic drugs (ANDA) | August 6, 2025 |
| Amneal Pharmaceuticals NY LLC | 12 | tablet, film coated; capsule | Generic drugs (ANDA) | August 21, 2023 |
| Leading Pharma, LLC | 12 | capsule; tablet, film coated | Generic drugs (ANDA) | April 15, 2021 |
| Zydus Lifesciences Limited | 12 | tablet, film coated; capsule | Generic drugs (ANDA) | June 30, 2024 |
| PD-Rx Pharmaceuticals, Inc. | 11 | capsule; tablet, film coated | Generic drugs (ANDA) | November 17, 2023 |
| Preferred Pharmaceuticals Inc. | 11 | tablet, film coated; tablet | Generic drugs (ANDA) | November 17, 2025 |
| Ajanta Pharma USA Inc. | 10 | capsule; tablet | Generic drugs (ANDA) | July 1, 2024 |
| Asclemed USA, Inc. | 10 | tablet, film coated; capsule | Generic drugs (ANDA) | November 17, 2023 |
| Lupin Pharmaceuticals, Inc. | 10 | capsule; tablet, film coated | Generic drugs (ANDA) | February 4, 2019 |
| Proficient Rx LP | 10 | capsule; tablet | Generic drugs (ANDA) | November 17, 2023 |
| Proficient Rx LP | 10 | capsule; tablet, film coated | Generic drugs (ANDA) | May 26, 2021 |
| SpecGx LLC | 10 | capsule | New drug applications (NDA) | June 1, 2015 |
| Sun Pharmaceutical Industries, Inc. | 10 | capsule; tablet | Generic drugs (ANDA) | September 30, 2026 |
| Zydus Pharmaceuticals USA Inc. | 10 | tablet, film coated; capsule | Generic drugs (ANDA) | February 10, 2022 |
| NorthStar Rx LLC | 9 | tablet, film coated; capsule | Generic drugs (ANDA) | August 25, 2021 |
| NorthStar RxLLC | 9 | capsule; tablet, film coated | Generic drugs (ANDA) | August 1, 2026 |
| Rising Pharma Holdings, Inc. | 9 | tablet; capsule | Generic drugs (ANDA) | June 10, 2023 |
| St. Mary's Medical Park Pharmacy | 9 | tablet; tablet, film coated | Generic drugs (ANDA) | October 29, 2026 |
| Aphena Pharma Solutions - Tennessee, LLC | 8 | tablet, film coated; capsule | Generic drugs (ANDA) | May 26, 2021 |
| Bryant Ranch Prepack | 8 | capsule; tablet | Generic drugs (ANDA) | September 12, 2022 |
| Major Pharmaceuticals | 8 | capsule; tablet | Generic drugs (ANDA) | March 8, 2024 |
| Advagen Pharma Ltd | 7 | tablet, film coated; solution | Generic drugs (ANDA) | May 1, 2023 |
| Epic Pharma, LLC | 7 | capsule; tablet, film coated | Generic drugs (ANDA) | March 3, 2022 |
| Novadoz Pharmaceuticals LLC | 7 | capsule; tablet | Generic drugs (ANDA) | April 3, 2023 |
| NuCare Pharmaceuticals,Inc. | 7 | tablet, film coated; capsule | Generic drugs (ANDA) | June 10, 2023 |
| Actavis Pharma, Inc. | 6 | tablet, film coated | Generic drugs (ANDA) | July 19, 2006 |
| AiPing Pharmaceutical, Inc. | 6 | tablet | Generic drugs (ANDA) | November 1, 2025 |
| Centaur Pharmaceuticals Private Limited | 6 | tablet | Generic drugs (ANDA) | June 6, 2022 |
| Heritage Pharmaceuticals Inc. D/B/A Avet Pharmaceuticals Inc. | 6 | capsule; tablet | Generic drugs (ANDA) | December 30, 2021 |
| Ingenus Pharmaceuticals, LLC | 6 | tablet | Generic drugs (ANDA) | September 19, 2018 |
| Proficient Rx LP | 6 | capsule; tablet, film coated | Generic drugs (ANDA) | December 5, 2014 |
| Sandoz Inc | 6 | tablet, film coated | Generic drugs (ANDA) | November 29, 1977 |
| Sun Pharmaceutical Industries, Inc. | 6 | tablet, film coated | Generic drugs (ANDA) | July 14, 1987 |
| Unichem Pharmaceuticals (USA), Inc. | 6 | tablet, film coated | Generic drugs (ANDA) | May 26, 2021 |
| Validus Pharmaceuticals LLC | 6 | tablet, sugar coated | New drug applications (NDA) | November 20, 1964 |
| Westminster Pharmaceuticals, LLC | 6 | tablet, coated | Generic drugs (ANDA) | May 20, 2024 |
| Appco Pharma LLC | 5 | capsule | Generic drugs (ANDA) | June 1, 2021 |
| AvPAK | 5 | tablet, film coated | Generic drugs (ANDA) | June 6, 2023 |
| Contract Pharmacal Corp. | 5 | capsule | Generic drugs (ANDA) | January 24, 2021 |
| First Nation Group, LLC | 5 | capsule | Generic drugs (ANDA) | January 11, 2023 |
| Florida Pharmaceutical Products, LLC | 5 | capsule | Generic drugs (ANDA) | May 1, 2021 |
| Northwind Health Company, LLC | 5 | tablet, film coated; capsule | Generic drugs (ANDA) | March 24, 2023 |
| Puracap Laboratories LLC DBA Blu Pharmaceuticals | 5 | capsule | Generic drugs (ANDA) | March 14, 2023 |
| Rising Pharma Holdings, Inc. | 5 | capsule | Generic drugs (ANDA) | December 25, 2023 |
| Strides Pharma Science Limited | 5 | tablet | Generic drugs (ANDA) | September 12, 2022 |
| Teva Pharmaceuticals USA, Inc. | 5 | capsule; cream | Generic drugs (ANDA) | February 17, 2023 |
| Actavis Pharma, Inc. | 4 | tablet | Generic drugs (ANDA) | August 28, 1992 |
| American Health Packaging | 4 | capsule; tablet, film coated | Generic drugs (ANDA) | December 9, 2025 |
| Bryant Ranch Prepack | 4 | capsule | Generic drugs (ANDA) | March 1, 2020 |
| Dr. Reddy's Laboratories Inc. | 4 | capsule | Generic drugs (ANDA) | November 17, 2023 |
| Hikma Pharmaceuticals USA Inc. | 4 | capsule | Generic drugs (ANDA) | April 19, 2010 |
| Mylan Institutional Inc. | 4 | capsule | Generic drugs (ANDA) | June 12, 1998 |
| Northwind Health Company, LLC | 4 | tablet, film coated; capsule | Generic drugs (ANDA) | November 26, 2025 |
| Safecor Health, LLC | 4 | capsule | Generic drugs (ANDA) | February 23, 2026 |
| Accord Healthcare Inc. | 3 | tablet, film coated | Generic drugs (ANDA) | December 26, 2014 |
| Breckenridge Pharmaceutical, Inc. | 3 | capsule | Generic drugs (ANDA) | April 5, 2017 |
| Direct RX | 3 | capsule | Generic drugs (ANDA) | September 15, 2021 |
| Elite Laboratories, Inc. | 3 | capsule | Generic drugs (ANDA) | November 21, 2011 |
| Micro Labs Limited | 3 | capsule | Generic drugs (ANDA) | September 1, 2020 |
| Oxford Pharmaceuticals, LLC | 3 | tablet | Generic drugs (ANDA) | August 1, 2020 |
| PD-Rx Pharmaceuticals, Inc. | 3 | tablet, film coated; capsule | Generic drugs (ANDA) | June 1, 2016 |
| Actavis Pharma, Inc. | 2 | tablet, film coated | Generic drugs (ANDA) | January 2, 2020 |
| American Health Packaging | 2 | capsule | Generic drugs (ANDA) | February 1, 2016 |
| Aphena Pharma Solutions - Tennessee, LLC | 2 | capsule | Generic drugs (ANDA) | May 13, 1986 |
| Archis Pharma LLC | 2 | tablet, film coated | Generic drugs (ANDA) | February 21, 2022 |
| Boswell Pharmacy Services LLC D/B/A BPS Wholesale | 2 | capsule | Generic drugs (ANDA) | September 4, 2024 |
| Currax Pharmaceuticals LLC | 2 | tablet | New drug applications (NDA) | August 1, 2010 |
| Currax Pharmaceuticals LLC DBA Cypress, Hawthorn, Macoven | 2 | tablet | Authorized generics (NDA) | August 1, 2010 |
| Marlex Pharmaceuticals, Inc. | 2 | tablet, film coated | Generic drugs (ANDA) | October 1, 2023 |
| Sigmapharm Laboratories, LLC | 2 | tablet, film coated | Generic drugs (ANDA) | March 2, 2020 |
| Viona Pharmaceuticals Inc | 2 | tablet | Generic drugs (ANDA) | June 30, 2024 |
| Key Therapeutics | 1 | tablet, film coated | Generic drugs (ANDA) | July 18, 2022 |
| Lannett Company, Inc. | 1 | solution | Generic drugs (ANDA) | December 29, 1998 |
| Mayne Pharma Inc. | 1 | capsule | Generic drugs (ANDA) | June 1, 2016 |
| PD-Rx Pharmaceuticals, Inc. | 1 | capsule | Generic drugs (ANDA) | May 13, 1986 |
| Pai Holdings, LLC DBA Pai Pharma | 1 | solution | Generic drugs (ANDA) | August 23, 2000 |
| Redpharm Drug | 1 | capsule | Generic drugs (ANDA) | June 28, 2017 |
Dosage forms
| Dosage form | Products | Share |
|---|---|---|
| Capsule | 315 | 47.2% |
| Tablet, film coated | 207 | 31% |
| Tablet | 113 | 16.9% |
| Tablet, coated | 18 | 2.7% |
| Tablet, sugar coated | 6 | 0.9% |
| Cream | 6 | 0.9% |
| Solution | 3 | 0.4% |
Updated November 6, 2026. Read from US Food and Drug Administration, National Drug Code Directory (openFDA). CC0 1.0 public domain dedication (openFDA). Counts are products in the FDA National Drug Code Directory on November 6, 2026: 138,262 products in commercial distribution, meaning without a marketing end date in the past. A company is a labeler code; one company can hold several codes, and the directory carries no address. Inclusion in the directory is not FDA approval, and the marketing category says under which kind of application or rule a product is sold. This page uses openFDA data and is not endorsed or certified by FDA. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.