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Data / Drug companies / Topoisomerase Inhibitor

Topoisomerase Inhibitor drugs: 8 drugs from 23 companies in the FDA NDC directory

Topoisomerase Inhibitor is an FDA established pharmacologic class. The FDA National Drug Code Directory lists 57 products in this class from 23 companies, covering 8 drugs by generic name. The main marketing category is generic drugs (ANDA), and the newest product started marketing on September 14, 2026.

SpecStream is the live web data engine for teams and agents. It reads the National Drug Code Directory that FDA publishes, and this page is that reading. Ask for the companies that make a drug, a class or a dosage form, with their headquarters, website and size added from the web, and new listings and discontinued products arrive in your sheet, CRM, Slack or agent as FDA posts them.

  • 23Companies
  • 57Products
  • 8Drugs by generic name

Drugs in the Topoisomerase Inhibitor class

Ranked by number of companies that list the drug.

DrugProducts hereCompanies listing it
Irinotecan hydrochloride2312
Etoposide189
Topotecan hydrochloride44
Topotecan43
Irinotecan hydrochloide33
Mitoxantrone32
Etoposide phosphate11
Mitoxantrone hydrochloride11

Companies with the most products in this class

CompanyProductsMain dosage formsMain marketing categoryNewest product started
Hikma Pharmaceuticals USA Inc.7injectionGeneric drugs (ANDA)December 20, 2010
BluePoint Laboratories5injection, solution, concentrate; injectionGeneric drugs (ANDA)December 1, 2025
Meitheal Pharmaceuticals Inc.5injection, solution, concentrateGeneric drugs (ANDA)June 1, 2025
Eugia US LLC4injection, solutionGeneric drugs (ANDA)April 11, 2022
Fresenius Kabi USA, LLC4injection, solution; injection, powder, lyophilized, for solutionGeneric drugs (ANDA)November 30, 2010
Accord Healthcare Inc.3injection; injection, powder, lyophilized, for solutionGeneric drugs (ANDA)July 8, 2020
Pharmacia & Upjohn Company LLC3injection, solutionNew drug applications (NDA)December 30, 2024
Qilu Pharmaceutical Co., Ltd.3injection, solutionGeneric drugs (ANDA)May 3, 2016
Actavis Pharma, Inc.2injection, solution; injection, powder, lyophilized, for solutionGeneric drugs (ANDA)March 12, 2015
Apotex Corp.2injection, solutionGeneric drugs (ANDA)July 1, 2023
Avyxa Pharma, LLC2injectionNew drug applications (NDA)September 14, 2026
Gland Pharma Limited2injectionGeneric drugs (ANDA)November 18, 2019
Hospira, Inc.2injection, solution, concentrate; injection, solutionGeneric drugs (ANDA)February 27, 2008
NorthStar Rx LLC2injectionGeneric drugs (ANDA)November 15, 2020
Sandoz Inc2capsuleNew drug applications (NDA)July 7, 2017
Xiromed, LLC2injectionGeneric drugs (ANDA)November 18, 2019
Amneal Pharmaceuticals NY LLC1capsuleAuthorized generics (NDA)May 15, 2026
H2-Pharma, LLC1injection, powder, lyophilized, for solutionNew drug applications (NDA)June 1, 2009
Hospira, Inc.1injection, solution, concentrateNew drug applications (NDA)February 21, 2011
Ipsen Biopharmaceuticals, Inc.1injection, powder, for solutionNew drug applications (NDA)October 22, 2015
Mylan Pharmaceuticals Inc.1capsuleGeneric drugs (ANDA)October 22, 2001
Novartis Pharmaceuticals Corporation1injection, powder, lyophilized, for solutionNew drug applications (NDA)December 21, 2016
Onesource Specialty Pharma Limited1capsuleNew drug applications (NDA)May 29, 2026

Dosage forms

Dosage formProductsShare
Injection1933.3%
Injection, solution1729.8%
Injection, solution, concentrate1017.5%
Capsule58.8%
Injection, powder, lyophilized, for solution58.8%
Injection, powder, for solution11.8%

Updated November 6, 2026. Read from US Food and Drug Administration, National Drug Code Directory (openFDA). CC0 1.0 public domain dedication (openFDA). Counts are products in the FDA National Drug Code Directory on November 6, 2026: 138,262 products in commercial distribution, meaning without a marketing end date in the past. A company is a labeler code; one company can hold several codes, and the directory carries no address. Inclusion in the directory is not FDA approval, and the marketing category says under which kind of application or rule a product is sold. This page uses openFDA data and is not endorsed or certified by FDA. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.