Data / Drug companies / Phosphodiesterase 5 Inhibitor
Phosphodiesterase 5 Inhibitor drugs: 8 drugs from 90 companies in the FDA NDC directory
Phosphodiesterase 5 Inhibitor is an FDA established pharmacologic class. The FDA National Drug Code Directory lists 539 products in this class from 90 companies, covering 8 drugs by generic name. The main marketing category is generic drugs (ANDA), and the newest product started marketing on September 1, 2026.
SpecStream is the live web data engine for teams and agents. It reads the National Drug Code Directory that FDA publishes, and this page is that reading. Ask for the companies that make a drug, a class or a dosage form, with their headquarters, website and size added from the web, and new listings and discontinued products arrive in your sheet, CRM, Slack or agent as FDA posts them.
- 90Companies
- 539Products
- 8Drugs by generic name
Drugs in the Phosphodiesterase 5 Inhibitor class
Ranked by number of companies that list the drug.
| Drug | Products here | Companies listing it |
|---|---|---|
| Tadalafil | 254 | 54 |
| Sildenafil | 181 | 53 |
| Sildenafil citrate | 55 | 24 |
| Vardenafil hydrochloride | 31 | 10 |
| Vardenafil | 12 | 6 |
| Avanafil | 3 | 1 |
| Macitentan and tadalafil | 2 | 1 |
| Sildenafil powder, | 1 | 1 |
Companies with the most products in this class
| Company | Products | Main dosage forms | Main marketing category | Newest product started |
|---|---|---|---|---|
| NuCare Pharmaceuticals,Inc. | 42 | tablet, film coated; tablet | Generic drugs (ANDA) | July 16, 2024 |
| Bryant Ranch Prepack | 29 | tablet, film coated; tablet | Generic drugs (ANDA) | January 18, 2022 |
| A-S Medication Solutions | 23 | tablet, film coated; tablet | Generic drugs (ANDA) | February 15, 2026 |
| Proficient Rx LP | 21 | tablet, film coated; tablet | Generic drugs (ANDA) | September 4, 2020 |
| Asclemed USA, Inc. | 20 | tablet, film coated; tablet | Generic drugs (ANDA) | February 19, 2020 |
| Camber Pharmaceuticals, Inc. | 16 | tablet, film coated; tablet | Generic drugs (ANDA) | June 14, 2024 |
| Macleods Pharmaceuticals Limited | 15 | tablet, film coated; tablet | Generic drugs (ANDA) | April 19, 2023 |
| Aphena Pharma Solutions - Tennessee, LLC | 13 | tablet; tablet, film coated | Generic drugs (ANDA) | November 27, 2024 |
| PD-Rx Pharmaceuticals, Inc. | 12 | tablet, film coated; tablet | Generic drugs (ANDA) | April 1, 2023 |
| Preferred Pharmaceuticals Inc. | 12 | tablet; tablet, film coated | Generic drugs (ANDA) | April 22, 2026 |
| Remedyrepack Inc. | 11 | tablet; tablet, film coated | Generic drugs (ANDA) | April 22, 2026 |
| Ajanta Pharma USA Inc. | 10 | tablet; tablet, film coated | Generic drugs (ANDA) | July 4, 2022 |
| Alembic Pharmaceuticals Inc. | 9 | tablet, coated; tablet, film coated | Generic drugs (ANDA) | August 5, 2020 |
| Alembic Pharmaceuticals Limited | 9 | tablet, coated; tablet, film coated | Generic drugs (ANDA) | August 5, 2020 |
| Aurobindo Pharma Limited | 9 | tablet, film coated; tablet | Generic drugs (ANDA) | March 26, 2019 |
| Proficient Rx LP | 9 | tablet, film coated; tablet | Generic drugs (ANDA) | June 16, 2021 |
| Solco Healthcare US, LLC | 9 | tablet | Generic drugs (ANDA) | November 27, 2024 |
| Torrent Pharmaceuticals Limited | 9 | tablet; tablet, film coated | Generic drugs (ANDA) | March 26, 2019 |
| Zydus Lifesciences Limited | 9 | tablet, film coated; powder, for suspension | Generic drugs (ANDA) | October 27, 2022 |
| Amneal Pharmaceuticals NY LLC | 8 | tablet, film coated; powder, for suspension | Generic drugs (ANDA) | March 2, 2024 |
| AvKARE | 8 | tablet; tablet, film coated | Generic drugs (ANDA) | July 28, 2025 |
| XLCare Pharmaceuticals, Inc. | 8 | tablet, film coated | Generic drugs (ANDA) | December 10, 2024 |
| Ani Pharmaceuticals, Inc. | 7 | tablet; for suspension | Generic drugs (ANDA) | August 29, 2023 |
| Bostal LLC | 7 | tablet, film coated | Generic drugs (ANDA) | April 22, 2020 |
| Hec Pharm USA Inc. | 7 | tablet, film coated | Generic drugs (ANDA) | June 11, 2020 |
| Nivagen Pharmaceuticals, Inc. | 7 | tablet, film coated; tablet | Generic drugs (ANDA) | June 16, 2021 |
| NorthStar RxLLC | 7 | tablet, film coated; tablet | Generic drugs (ANDA) | August 3, 2026 |
| Northwind Health Company, LLC | 7 | tablet, film coated; tablet | Generic drugs (ANDA) | April 19, 2023 |
| Teva Pharmaceuticals USA, Inc. | 7 | tablet, film coated | Generic drugs (ANDA) | January 3, 2019 |
| Umedica Laboratories USA Inc. | 7 | tablet, film coated | Generic drugs (ANDA) | February 15, 2026 |
| Viatris Specialty LLC | 6 | tablet, film coated; injection, solution | New drug applications (NDA) | June 22, 2026 |
| Amneal Pharmaceuticals NY LLC | 5 | tablet, film coated; powder, for suspension | Generic drugs (ANDA) | December 6, 2019 |
| Bryant Ranch Prepack | 5 | tablet, film coated; tablet | Generic drugs (ANDA) | March 27, 2019 |
| Dr. Reddy's Laboratories Inc. | 5 | tablet, film coated | Generic drugs (ANDA) | March 26, 2019 |
| Quallent Pharmaceuticals Health LLC | 5 | tablet; tablet, film coated | Generic drugs (ANDA) | July 19, 2023 |
| Zydus Pharmaceuticals USA Inc. | 5 | tablet, film coated; powder, for suspension | Generic drugs (ANDA) | October 27, 2022 |
| Accord Healthcare Inc. | 4 | tablet, film coated | Generic drugs (ANDA) | April 3, 2020 |
| Advagen Pharma Ltd | 4 | tablet, film coated | Generic drugs (ANDA) | June 17, 2021 |
| Advanced Rx of Tennessee, LLC | 4 | tablet, film coated; tablet | Generic drugs (ANDA) | March 20, 2025 |
| Burel Pharmaceuticals, LLC | 4 | tablet, film coated | Generic drugs (ANDA) | April 1, 2023 |
| Cipla USA Inc. | 4 | tablet; tablet, film coated | Generic drugs (ANDA) | July 10, 2020 |
| Fourrts (india) Laboratories Private Limited | 4 | tablet, film coated | Generic drugs (ANDA) | August 21, 2024 |
| Ibsa Pharma Inc. | 4 | film | New drug applications (NDA) | February 15, 2026 |
| Jubilant Cadista Pharmaceuticals Inc. | 4 | tablet, film coated | Generic drugs (ANDA) | September 1, 2026 |
| Lannett Company, Inc. | 4 | tablet | Generic drugs (ANDA) | November 1, 2018 |
| NorthStar Rx LLC | 4 | tablet, film coated | Generic drugs (ANDA) | February 19, 2020 |
| Pfizer Laboratories Div Pfizer Inc | 4 | tablet, film coated | New drug applications (NDA) | June 3, 2005 |
| Qilu Pharmaceutical Co., Ltd. | 4 | tablet, film coated | Generic drugs (ANDA) | November 17, 2021 |
| Sun Pharmaceutical Industries, Inc. | 4 | tablet, film coated | Generic drugs (ANDA) | March 26, 2019 |
| TruPharma, LLC | 4 | tablet, film coated | Generic drugs (ANDA) | June 11, 2018 |
| Unichem Pharmaceuticals (USA), Inc. | 4 | tablet, film coated | Generic drugs (ANDA) | March 26, 2019 |
| Upsher-Smith Laboratories, LLC | 4 | tablet, film coated | Generic drugs (ANDA) | April 7, 2024 |
| VKT Pharma Private Limited | 4 | tablet, film coated | Generic drugs (ANDA) | November 4, 2021 |
| Yaral Pharma Inc. | 4 | film | New drug applications (NDA) | February 15, 2026 |
| Zydus Pharmaceuticals USA Inc. | 4 | tablet, film coated | Generic drugs (ANDA) | March 27, 2019 |
| Appco Pharma LLC | 3 | tablet | Generic drugs (ANDA) | October 5, 2023 |
| Bryant Ranch Prepack | 3 | tablet; tablet, film coated | Generic drugs (ANDA) | November 1, 2018 |
| Cadila Pharmaceuticals Limited | 3 | tablet, film coated | Generic drugs (ANDA) | December 1, 2023 |
| Direct_Rx | 3 | tablet; tablet, film coated | Generic drugs (ANDA) | November 29, 2021 |
| Eli Lilly and Company | 3 | tablet, film coated | New drug applications (NDA) | November 26, 2003 |
| Exelan Pharmaceuticals Inc. | 3 | tablet | Generic drugs (ANDA) | July 1, 2022 |
| Modavar Pharmaceuticals LLC | 3 | tablet, film coated | Generic drugs (ANDA) | February 14, 2024 |
| Mylan Pharmaceuticals Inc. | 3 | tablet, film coated | Authorized generics (NDA) | December 1, 2017 |
| PD-Rx Pharmaceuticals, Inc. | 3 | tablet, film coated | Generic drugs (ANDA) | June 11, 2018 |
| Proficient Rx LP | 3 | tablet, film coated; tablet | Generic drugs (ANDA) | November 26, 2014 |
| Reyoung Corporation | 3 | tablet, film coated | Generic drugs (ANDA) | March 28, 2022 |
| Teva Pharmaceuticals, Inc. | 3 | tablet, film coated | Generic drugs (ANDA) | February 20, 2024 |
| Actelion Pharmaceuticals US, Inc. | 2 | tablet, film coated | New drug applications (NDA) | March 22, 2024 |
| BluePoint Laboratories | 2 | tablet, film coated | Generic drugs (ANDA) | June 12, 2023 |
| Chartwell RX, LLC | 2 | tablet; tablet, film coated | Generic drugs (ANDA) | October 31, 2018 |
| Lupin Pharmaceuticals, Inc. | 2 | powder, for suspension; tablet, film coated | Generic drugs (ANDA) | September 28, 2022 |
| Northwind Health Company, LLC | 2 | tablet; tablet, film coated | Generic drugs (ANDA) | November 26, 2025 |
| Redpharm Drug | 2 | tablet, film coated | Generic drugs (ANDA) | March 26, 2019 |
| Actavis Pharma, Inc. | 1 | powder, for suspension | Generic drugs (ANDA) | August 17, 2020 |
| American Health Packaging | 1 | tablet, film coated | Generic drugs (ANDA) | November 13, 2023 |
| Amneal Pharmaceuticals LLC | 1 | tablet | Generic drugs (ANDA) | November 8, 2012 |
| Amneal Pharmaceuticals of New York LLC | 1 | tablet | Generic drugs (ANDA) | November 8, 2012 |
| Aphena Pharma Solutions - Tennessee, LLC | 1 | tablet | Generic drugs (ANDA) | February 24, 2026 |
| Ascend Laboratories, LLC | 1 | powder, for suspension | Generic drugs (ANDA) | November 29, 2019 |
| Aurobindo Pharma Limited | 1 | powder, for suspension | Generic drugs (ANDA) | December 23, 2022 |
| AvKARE | 1 | tablet | Generic drugs (ANDA) | August 11, 2025 |
| AvPAK | 1 | tablet | Generic drugs (ANDA) | May 29, 2015 |
| CMP Pharma, Inc. | 1 | suspension | New drug applications (NDA) | August 30, 2022 |
| Cardinal Health 107, LLC | 1 | tablet, film coated | Generic drugs (ANDA) | November 6, 2012 |
| Eugia US LLC | 1 | injection, solution | Generic drugs (ANDA) | April 1, 2015 |
| Golden State Medical Supply, Inc. | 1 | tablet, film coated | Generic drugs (ANDA) | March 6, 2025 |
| Major Pharmaceuticals | 1 | tablet, film coated | Generic drugs (ANDA) | November 6, 2012 |
| Novadoz Pharmaceuticals LLC | 1 | powder, for suspension | Generic drugs (ANDA) | February 14, 2022 |
| United Therapeutics Corporation | 1 | tablet | New drug applications (NDA) | May 22, 2009 |
| Virtus Pharmaceuticals, LLC | 1 | for suspension | Generic drugs (ANDA) | August 2, 2021 |
Dosage forms
| Dosage form | Products | Share |
|---|---|---|
| Tablet, film coated | 354 | 65.7% |
| Tablet | 150 | 27.8% |
| Powder, for suspension | 11 | 2% |
| Film | 8 | 1.5% |
| Tablet, coated | 8 | 1.5% |
| For suspension | 3 | 0.6% |
| Injection, solution | 2 | 0.4% |
| Tablet, orally disintegrating | 2 | 0.4% |
| Suspension | 1 | 0.2% |
Updated November 6, 2026. Read from US Food and Drug Administration, National Drug Code Directory (openFDA). CC0 1.0 public domain dedication (openFDA). Counts are products in the FDA National Drug Code Directory on November 6, 2026: 138,262 products in commercial distribution, meaning without a marketing end date in the past. A company is a labeler code; one company can hold several codes, and the directory carries no address. Inclusion in the directory is not FDA approval, and the marketing category says under which kind of application or rule a product is sold. This page uses openFDA data and is not endorsed or certified by FDA. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.