Data / Drug companies / Opioid Agonist/Antagonist
Opioid Agonist/Antagonist drugs: 3 drugs from 10 companies in the FDA NDC directory
Opioid Agonist/Antagonist is an FDA established pharmacologic class. The FDA National Drug Code Directory lists 25 products in this class from 10 companies, covering 3 drugs by generic name. The main marketing category is generic drugs (ANDA), and the newest product started marketing on December 11, 2025.
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- 10Companies
- 25Products
- 3Drugs by generic name
Drugs in the Opioid Agonist/Antagonist class
Ranked by number of companies that list the drug.
| Drug | Products here | Companies listing it |
|---|---|---|
| Nalbuphine hydrochloride | 16 | 5 |
| Butorphanol tartrate | 7 | 5 |
| Nalbuphine hci | 2 | 1 |
Companies with the most products in this class
| Company | Products | Main dosage forms | Main marketing category | Newest product started |
|---|---|---|---|---|
| Hospira, Inc. | 7 | injection, solution | Generic drugs (ANDA) | June 27, 2008 |
| Somerset Therapeutics, LLC | 4 | injection | Generic drugs (ANDA) | September 26, 2024 |
| Henry Schein, Inc. | 3 | injection; injection, solution | Generic drugs (ANDA) | December 11, 2025 |
| Medical Purchasing Solutions, LLC | 3 | injection, solution; injection | Generic drugs (ANDA) | September 26, 2024 |
| HF Acquisition Co LLC, DBA HealthFirst | 2 | injection, solution | Generic drugs (ANDA) | October 29, 2019 |
| Hikma Pharmaceuticals USA Inc. | 2 | injection, solution | Generic drugs (ANDA) | May 1, 2009 |
| Apotex Corp. | 1 | spray | Generic drugs (ANDA) | December 4, 2002 |
| Bryant Ranch Prepack | 1 | spray | Generic drugs (ANDA) | December 4, 2002 |
| Hikma Pharmaceuticals USA Inc. | 1 | spray, metered | Generic drugs (ANDA) | March 12, 2002 |
| ProPharma Distribution | 1 | injection, solution | Generic drugs (ANDA) | July 19, 2005 |
Dosage forms
| Dosage form | Products | Share |
|---|---|---|
| Injection, solution | 15 | 60% |
| Injection | 7 | 28% |
| Spray | 2 | 8% |
| Spray, metered | 1 | 4% |
Updated November 6, 2026. Read from US Food and Drug Administration, National Drug Code Directory (openFDA). CC0 1.0 public domain dedication (openFDA). Counts are products in the FDA National Drug Code Directory on November 6, 2026: 138,262 products in commercial distribution, meaning without a marketing end date in the past. A company is a labeler code; one company can hold several codes, and the directory carries no address. Inclusion in the directory is not FDA approval, and the marketing category says under which kind of application or rule a product is sold. This page uses openFDA data and is not endorsed or certified by FDA. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.