Data / Drug companies / Opioid Agonist
Opioid Agonist drugs: 65 drugs from 207 companies in the FDA NDC directory
Opioid Agonist is an FDA established pharmacologic class. The FDA National Drug Code Directory lists 1,455 products in this class from 207 companies, covering 65 drugs by generic name. The main marketing category is generic drugs (ANDA), and the newest product started marketing on November 3, 2026.
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- 207Companies
- 1,455Products
- 65Drugs by generic name
Drugs in the Opioid Agonist class
Ranked by number of companies that list the drug.
Companies with the most products in this class
| Company | Products | Main dosage forms | Main marketing category | Newest product started |
|---|---|---|---|---|
| Bryant Ranch Prepack | 90 | tablet; capsule | Generic drugs (ANDA) | September 10, 2024 |
| Bryant Ranch Prepack | 69 | tablet; tablet, film coated, extended release | Generic drugs (ANDA) | February 11, 2021 |
| SpecGx LLC | 47 | tablet; patch, extended release | Generic drugs (ANDA) | September 1, 2023 |
| Bryant Ranch Prepack | 40 | tablet; tablet, film coated, extended release | Generic drugs (ANDA) | November 2, 2020 |
| Asclemed USA, Inc. | 38 | tablet; tablet, extended release | Generic drugs (ANDA) | September 10, 2024 |
| Hikma Pharmaceuticals USA Inc. | 33 | tablet; solution | Generic drugs (ANDA) | December 15, 2025 |
| NuCare Pharmaceuticals,Inc. | 32 | tablet; capsule | Generic drugs (ANDA) | December 1, 2024 |
| Direct_Rx | 28 | tablet; tablet, extended release | Generic drugs (ANDA) | August 25, 2026 |
| Hikma Pharmaceuticals USA Inc. | 28 | injection; injection, solution | Generic drugs (ANDA) | August 29, 2025 |
| Rhodes Pharmaceuticals LLC | 27 | tablet; tablet, film coated, extended release | Generic drugs (ANDA) | May 15, 2017 |
| Aurolife Pharma, LLC | 26 | tablet; solution | Generic drugs (ANDA) | January 27, 2020 |
| Camber Pharmaceuticals, Inc. | 25 | tablet; tablet, extended release | Generic drugs (ANDA) | November 14, 2025 |
| Alvogen Inc. | 24 | tablet, extended release; tablet | Generic drugs (ANDA) | March 3, 2021 |
| St. Mary's Medical Park Pharmacy | 24 | tablet; tablet, film coated | Generic drugs (ANDA) | August 6, 2026 |
| KVK-Tech, Inc. | 23 | tablet; solution | Generic drugs (ANDA) | December 5, 2019 |
| Lupin Pharmaceuticals,Inc. | 22 | tablet; tablet, film coated, extended release | Generic drugs (ANDA) | June 12, 2017 |
| XLCare Pharmaceuticals, Inc. | 22 | tablet; tablet, extended release | Generic drugs (ANDA) | September 24, 2020 |
| Epic Pharma, LLC | 21 | tablet; tablet, film coated | Generic drugs (ANDA) | December 31, 2021 |
| Hospira, Inc. | 21 | injection, solution | New drug applications (NDA) | April 21, 2025 |
| Redpharm Drug | 20 | tablet; solution | Generic drugs (ANDA) | September 10, 2024 |
| Proficient Rx LP | 19 | tablet; tablet, coated | Generic drugs (ANDA) | January 5, 2017 |
| American Health Packaging | 16 | tablet; solution | Generic drugs (ANDA) | September 9, 2026 |
| Fresenius Kabi USA, LLC | 16 | injection, solution; injection, powder, lyophilized, for solution | New drug applications (NDA) | January 15, 2021 |
| Major Pharmaceuticals | 16 | tablet; tablet, film coated, extended release | Generic drugs (ANDA) | December 20, 2024 |
| Preferred Pharmaceuticals Inc. | 16 | tablet; tablet, film coated | Generic drugs (ANDA) | June 8, 2026 |
| Advanced Rx of Tennessee, LLC | 15 | tablet; tablet, extended release | Generic drugs (ANDA) | June 26, 2026 |
| Amneal Pharmaceuticals of New York LLC | 15 | tablet, film coated, extended release; capsule, extended release | Generic drugs (ANDA) | October 5, 2018 |
| Eywa Pharma Inc | 15 | tablet; solution | Generic drugs (ANDA) | August 2, 2019 |
| Proficient Rx LP | 14 | tablet, extended release; tablet | Generic drugs (ANDA) | September 23, 2020 |
| Collegium Pharmaceutical, Inc. | 13 | capsule, extended release; tablet, film coated, extended release | New drug applications (NDA) | April 19, 2019 |
| Knoa Pharma LLC | 13 | tablet, film coated, extended release; tablet, extended release | New drug applications (NDA) | January 15, 2015 |
| Pai Holdings, LLC DBA Pai Pharma | 13 | solution | Generic drugs (ANDA) | September 15, 2025 |
| Strides Pharma Science Limited | 13 | tablet | Generic drugs (ANDA) | September 1, 2026 |
| Cranbury Pharmaceuticals, LLC | 12 | tablet; solution | Generic drugs (ANDA) | December 22, 2024 |
| Elite Laboratories, Inc. | 12 | tablet | Generic drugs (ANDA) | September 10, 2019 |
| Remedyrepack Inc. | 12 | tablet; tablet, extended release | Generic drugs (ANDA) | November 3, 2026 |
| A-S Medication Solutions | 11 | tablet; tablet, film coated | Generic drugs (ANDA) | September 5, 2023 |
| Precision Dose, Inc. | 11 | solution; tablet | New drug applications (NDA) | September 1, 2025 |
| Amneal Pharmaceuticals LLC | 10 | tablet; syrup | Generic drugs (ANDA) | June 30, 2016 |
| Asclemed USA Inc. | 10 | tablet; tablet, film coated | Generic drugs (ANDA) | August 9, 2019 |
| Amneal Pharmaceuticals of New York LLC | 9 | tablet | Generic drugs (ANDA) | February 18, 2010 |
| Fresenius Kabi USA, LLC | 9 | injection, solution | New drug applications (NDA) | December 4, 2018 |
| Mylan Pharmaceuticals Inc. | 9 | patch; capsule | Generic drugs (ANDA) | February 26, 2015 |
| Padagis US LLC | 9 | suppository; tablet, extended release | Other unapproved drugs | May 22, 2015 |
| Proficient Rx LP | 9 | tablet; tablet, film coated, extended release | Generic drugs (ANDA) | September 1, 2025 |
| Upsher-Smith Laboratories, LLC | 9 | capsule, extended release; tablet | Generic drugs (ANDA) | July 22, 2019 |
| Amazon.com Services LLC | 8 | tablet; solution | Generic drugs (ANDA) | September 24, 2026 |
| American Health Packaging | 8 | tablet; tablet, film coated, extended release | Generic drugs (ANDA) | February 25, 2020 |
| AvPAK | 8 | tablet; capsule | Generic drugs (ANDA) | April 5, 2023 |
| Aveva Drug Delivery Systems Inc. | 8 | patch, extended release | Generic drugs (ANDA) | February 11, 2025 |
| Genus Lifesciences | 8 | solution; tablet | Generic drugs (ANDA) | May 15, 2026 |
| Ingenus Pharmaceuticals, LLC | 8 | patch, extended release | Generic drugs (ANDA) | February 11, 2025 |
| Amneal Pharmaceuticals LLC | 7 | tablet, film coated, extended release | Generic drugs (ANDA) | January 2, 2013 |
| Granules Pharmaceuticals Inc. | 7 | tablet | Generic drugs (ANDA) | January 1, 2022 |
| Trigen Laboratories, LLC | 7 | tablet, extended release; capsule | Generic drugs (ANDA) | September 15, 2016 |
| Actavis Pharma, Inc. | 6 | capsule, extended release | Generic drugs (ANDA) | February 4, 2014 |
| Ascent Pharmaceuticals, Inc. | 6 | solution; tablet | Generic drugs (ANDA) | May 4, 2019 |
| Aurohealth LLC | 6 | tablet; capsule, liquid filled | Generic drugs (ANDA) | December 29, 2025 |
| Bionpharma Inc. | 6 | capsule, liquid filled; tablet | Generic drugs (ANDA) | March 2, 2026 |
| Dolgencorp, Inc. (dollar General & Rexall) | 6 | solution; tablet | Generic drugs (ANDA) | March 30, 2026 |
| L. Perrigo Company | 6 | tablet, film coated; tablet | Generic drugs (ANDA) | August 9, 2022 |
| Lannett Company, Inc. | 6 | tablet; concentrate | Generic drugs (ANDA) | November 2, 2020 |
| Lupin Pharmaceuticals, Inc. | 6 | tablet, extended release | Generic drugs (ANDA) | August 19, 2014 |
| Nortec Development Associates, Inc. | 6 | capsule, extended release | Generic drugs (ANDA) | April 7, 2009 |
| Sun Pharmaceutical Industries, Inc. | 6 | tablet, extended release | Generic drugs (ANDA) | December 30, 2011 |
| VistaPharm, LLC | 6 | tablet; concentrate | Generic drugs (ANDA) | September 11, 2020 |
| Walgreen Company | 6 | tablet; capsule, liquid filled | Generic drugs (ANDA) | August 3, 2022 |
| Yyba Corp | 6 | tablet; capsule | Generic drugs (ANDA) | September 1, 2026 |
| Advagen Pharma Ltd | 5 | tablet, coated; capsule | Generic drugs (ANDA) | November 28, 2023 |
| American Health Packaging | 5 | solution | Generic drugs (ANDA) | May 1, 2026 |
| Aphena Pharma Solutions - Tennessee, LLC | 5 | capsule; tablet, film coated | Generic drugs (ANDA) | October 6, 2021 |
| Cardinal Health 110, LLC. DBA Leader | 5 | tablet, film coated; solution | Generic drugs (ANDA) | October 7, 2021 |
| Direct RX | 5 | tablet; tablet, extended release | Generic drugs (ANDA) | August 21, 2019 |
| FH2 Pharma LLC | 5 | tablet; solution | Generic drugs (ANDA) | March 2, 2021 |
| Forte Bio-Pharma LLC | 5 | tablet; solution | Generic drugs (ANDA) | March 1, 2020 |
| H E B | 5 | tablet; tablet, film coated | Generic drugs (ANDA) | December 4, 2018 |
| Lil' Drug Store Products, Inc. | 5 | tablet | Generic drugs (ANDA) | August 1, 2023 |
| Quality Care Products, LLC | 5 | tablet; tablet, coated | Generic drugs (ANDA) | April 6, 2023 |
| Safeway | 5 | tablet; solution | Generic drugs (ANDA) | April 7, 2025 |
| Sun Pharmaceutical Industries, Inc. | 5 | tablet, film coated, extended release | Generic drugs (ANDA) | May 11, 2012 |
| Amerisource Bergen | 4 | tablet; capsule, liquid filled | Generic drugs (ANDA) | July 5, 2023 |
| Ascend Laboratories, LLC | 4 | tablet | Generic drugs (ANDA) | July 1, 2025 |
| Atlantic Biologicals Corp. | 4 | concentrate; solution | Generic drugs (ANDA) | November 2, 2020 |
| Civica, Inc. | 4 | injection | New drug applications (NDA) | October 7, 2020 |
| Coupler LLC | 4 | tablet, coated; tablet, extended release | Generic drugs (ANDA) | June 22, 2026 |
| Discount Drug Mart | 4 | tablet; capsule, liquid filled | Generic drugs (ANDA) | February 26, 2025 |
| Kenvue Brands LLC | 4 | solution; tablet | New drug applications (NDA) | July 11, 2016 |
| Kroger Company | 4 | tablet; capsule, liquid filled | Generic drugs (ANDA) | May 6, 2020 |
| Meijer Distribution Inc | 4 | tablet; solution | Generic drugs (ANDA) | February 1, 2019 |
| Mylan Institutional LLC | 4 | injection, powder, lyophilized, for solution; injection, solution | New drug applications (NDA) | April 15, 2020 |
| Par Health USA, LLC | 4 | tablet | Generic drugs (ANDA) | March 6, 2003 |
| Protega Pharmaceuticals Inc | 4 | tablet, coated | New drug applications (NDA) | April 20, 2017 |
| Rite Aid Corporation | 4 | tablet; capsule, liquid filled | Generic drugs (ANDA) | January 24, 2020 |
| Strategic Sourcing Services LLC | 4 | capsule, liquid filled; tablet, film coated | Generic drugs (ANDA) | November 8, 2023 |
| Target Corporation | 4 | tablet, film coated; tablet | Generic drugs (ANDA) | October 9, 2019 |
| Wal-Mart Stores Inc | 4 | suspension; tablet | Generic drugs (ANDA) | September 3, 2020 |
| American Sales Company | 3 | suspension; tablet | Generic drugs (ANDA) | January 31, 2019 |
| Ani Pharmaceuticals, Inc. | 3 | solution; capsule | Generic drugs (ANDA) | June 10, 2016 |
| AvKARE | 3 | tablet, film coated | Generic drugs (ANDA) | September 14, 2026 |
| Breckenridge Pharmaceutical, Inc. | 3 | capsule; injection, solution | Generic drugs (ANDA) | December 30, 2024 |
Dosage forms
| Dosage form | Products | Share |
|---|---|---|
| Tablet | 744 | 51.1% |
| Solution | 132 | 9.1% |
| Tablet, extended release | 86 | 5.9% |
| Tablet, film coated, extended release | 77 | 5.3% |
| Tablet, film coated | 66 | 4.5% |
| Capsule | 65 | 4.5% |
| Injection, solution | 50 | 3.4% |
| Tablet, coated | 40 | 2.7% |
| Capsule, extended release | 40 | 2.7% |
| Injection | 34 | 2.3% |
| Capsule, liquid filled | 32 | 2.2% |
| Patch, extended release | 23 | 1.6% |
Updated November 6, 2026. Read from US Food and Drug Administration, National Drug Code Directory (openFDA). CC0 1.0 public domain dedication (openFDA). Counts are products in the FDA National Drug Code Directory on November 6, 2026: 138,262 products in commercial distribution, meaning without a marketing end date in the past. A company is a labeler code; one company can hold several codes, and the directory carries no address. Inclusion in the directory is not FDA approval, and the marketing category says under which kind of application or rule a product is sold. This page uses openFDA data and is not endorsed or certified by FDA. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.