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Data / Drug companies / Endothelin Receptor Antagonist

Endothelin Receptor Antagonist drugs: 7 drugs from 28 companies in the FDA NDC directory

Endothelin Receptor Antagonist is an FDA established pharmacologic class. The FDA National Drug Code Directory lists 61 products in this class from 28 companies, covering 7 drugs by generic name. The main marketing category is generic drugs (ANDA), and the newest product started marketing on October 1, 2026.

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  • 28Companies
  • 61Products
  • 7Drugs by generic name

Drugs in the Endothelin Receptor Antagonist class

Ranked by number of companies that list the drug.

DrugProducts hereCompanies listing it
Macitentan1515
Ambrisentan2613
Bosentan147
Macitentan and tadalafil21
Sparsentan21
Aprocitentan11
Atrasentan11

Companies with the most products in this class

CompanyProductsMain dosage formsMain marketing categoryNewest product started
Actelion Pharmaceuticals US, Inc.6tablet, film coated; tablet, for suspensionNew drug applications (NDA)March 22, 2024
Sun Pharmaceutical Industries, Inc.5tablet, film coatedGeneric drugs (ANDA)June 6, 2026
Zydus Lifesciences Limited5tablet; tablet, film coatedGeneric drugs (ANDA)February 17, 2026
Actavis Pharma, Inc.4tablet, film coatedGeneric drugs (ANDA)June 19, 2019
Zydus Pharmaceuticals USA Inc.4tablet, film coated; tablet, for suspensionGeneric drugs (ANDA)February 17, 2026
Apotex Corp.3tablet, film coatedGeneric drugs (ANDA)June 11, 2026
Aurobindo Pharma Limited3tablet, film coatedGeneric drugs (ANDA)June 8, 2026
Mylan Pharmaceuticals Inc.3tablet, film coatedGeneric drugs (ANDA)June 8, 2026
A-S Medication Solutions2tablet, film coatedGeneric drugs (ANDA)July 21, 2022
Cipla USA Inc.2tablet, film coatedGeneric drugs (ANDA)April 26, 2019
Gilead Sciences, Inc.2tablet, film coatedNew drug applications (NDA)June 15, 2007
Golden State Medical Supply, Inc.2tablet, film coatedGeneric drugs (ANDA)May 19, 2022
Quallent Pharmaceuticals Health LLC2tablet, film coatedGeneric drugs (ANDA)May 1, 2024
Sigmapharm Laboratories, LLC2tablet, film coatedGeneric drugs (ANDA)April 10, 2019
Travere Therapeutics, Inc.2tablet, film coatedNew drug applications (NDA)February 17, 2023
Zydus Pharmaceuticals USA Inc.2tablet, coatedGeneric drugs (ANDA)May 1, 2019
Alembic Pharmaceuticals Inc.1tablet, film coatedGeneric drugs (ANDA)June 6, 2026
Alembic Pharmaceuticals Limited1tablet, film coatedGeneric drugs (ANDA)June 6, 2026
Amneal Pharmaceuticals NY LLC1tablet, film coatedGeneric drugs (ANDA)June 8, 2026
Ani Pharmaceuticals, Inc.1tablet, film coatedGeneric drugs (ANDA)October 1, 2026
Idorsia Pharmaceuticals Ltd1tablet, film coatedNew drug applications (NDA)March 20, 2024
Laurus Labs Limited1tablet, film coatedGeneric drugs (ANDA)May 15, 2026
Lupin Pharmaceuticals, Inc.1tablet, for suspensionGeneric drugs (ANDA)August 18, 2025
Novartis Pharmaceuticals Corporation1tablet, film coatedNew drug applications (NDA)April 2, 2025
Novugen Pharma (USA) LLC1tablet, film coatedGeneric drugs (ANDA)May 7, 2026
Sandoz Inc1tablet, film coatedGeneric drugs (ANDA)August 20, 2025
Teva Pharmaceuticals, Inc.1tablet, film coatedGeneric drugs (ANDA)June 8, 2026
Torrent Pharmaceuticals Limited1tabletGeneric drugs (ANDA)June 1, 2026

Dosage forms

Dosage formProductsShare
Tablet, film coated5285.2%
Tablet, for suspension46.6%
Tablet34.9%
Tablet, coated23.3%

Updated November 6, 2026. Read from US Food and Drug Administration, National Drug Code Directory (openFDA). CC0 1.0 public domain dedication (openFDA). Counts are products in the FDA National Drug Code Directory on November 6, 2026: 138,262 products in commercial distribution, meaning without a marketing end date in the past. A company is a labeler code; one company can hold several codes, and the directory carries no address. Inclusion in the directory is not FDA approval, and the marketing category says under which kind of application or rule a product is sold. This page uses openFDA data and is not endorsed or certified by FDA. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.