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Data / Drug companies / Catechol-O-Methyltransferase Inhibitor

Catechol-O-Methyltransferase Inhibitor drugs: 5 drugs from 19 companies in the FDA NDC directory

Catechol-O-Methyltransferase Inhibitor is an FDA established pharmacologic class. The FDA National Drug Code Directory lists 49 products in this class from 19 companies, covering 5 drugs by generic name. The main marketing category is generic drugs (ANDA), and the newest product started marketing on April 23, 2026.

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  • 19Companies
  • 49Products
  • 5Drugs by generic name

Drugs in the Catechol-O-Methyltransferase Inhibitor class

Ranked by number of companies that list the drug.

DrugProducts hereCompanies listing it
Entacapone1414
Carbidopa, levodopa and entacapone244
Tolcapone33
Carbidopa, levodopa, and entacapone61
Opicapone21

Companies with the most products in this class

CompanyProductsMain dosage formsMain marketing categoryNewest product started
Alembic Pharmaceuticals Inc.7tablet, film coatedGeneric drugs (ANDA)February 12, 2026
Alembic Pharmaceuticals Limited7tablet, film coatedGeneric drugs (ANDA)February 12, 2026
Macleods Pharmaceuticals Limited7tablet, film coated; tabletGeneric drugs (ANDA)April 15, 2025
Sandoz Inc7tablet, film coatedAuthorized generics (NDA)June 18, 2014
Rising Pharma Holdings, Inc.6tablet, film coatedGeneric drugs (ANDA)August 5, 2021
Amneal Pharmaceuticals LLC2capsuleNew drug applications (NDA)April 5, 2024
Ajanta Pharma USA Inc.1tabletGeneric drugs (ANDA)August 31, 2017
American Health Packaging1tablet, film coatedGeneric drugs (ANDA)June 2, 2016
Aphena Pharma Solutions - Tennessee, LLC1tablet, film coatedAuthorized generics (NDA)June 4, 2014
Aurobindo Pharma Limited1tablet, film coatedGeneric drugs (ANDA)June 19, 2015
AvPAK1tablet, film coatedGeneric drugs (ANDA)December 5, 2016
Bausch Health US LLC1tablet, film coatedNew drug applications (NDA)July 27, 2004
Ingenus Pharmaceuticals, LLC1tabletGeneric drugs (ANDA)August 21, 2018
Lannett Company, Inc.1tablet, film coatedGeneric drugs (ANDA)December 20, 2018
Major Pharmaceuticals1tablet, film coatedGeneric drugs (ANDA)June 19, 2015
NCS HealthCare of Ky, LLC DBA Vangard Labs1tabletGeneric drugs (ANDA)June 6, 2017
Oceanside Pharmaceuticals1tablet, film coatedAuthorized generics (NDA)July 27, 2004
Rising Pharma Holdings, Inc.1tablet, film coatedGeneric drugs (ANDA)April 23, 2026
Sun Pharmaceutical Industries, Inc.1tablet, film coatedAuthorized generics (NDA)April 1, 2013

Dosage forms

Dosage formProductsShare
Tablet, film coated4387.8%
Tablet48.2%
Capsule24.1%

Updated November 6, 2026. Read from US Food and Drug Administration, National Drug Code Directory (openFDA). CC0 1.0 public domain dedication (openFDA). Counts are products in the FDA National Drug Code Directory on November 6, 2026: 138,262 products in commercial distribution, meaning without a marketing end date in the past. A company is a labeler code; one company can hold several codes, and the directory carries no address. Inclusion in the directory is not FDA approval, and the marketing category says under which kind of application or rule a product is sold. This page uses openFDA data and is not endorsed or certified by FDA. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.