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Data / Drug companies / Antihistamine

Antihistamine drugs: 31 drugs from 170 companies in the FDA NDC directory

Antihistamine is an FDA established pharmacologic class. The FDA National Drug Code Directory lists 787 products in this class from 170 companies, covering 31 drugs by generic name. The main marketing category is over the counter monograph drugs, and the newest product started marketing on October 5, 2026.

SpecStream is the live web data engine for teams and agents. It reads the National Drug Code Directory that FDA publishes, and this page is that reading. Ask for the companies that make a drug, a class or a dosage form, with their headquarters, website and size added from the web, and new listings and discontinued products arrive in your sheet, CRM, Slack or agent as FDA posts them.

  • 170Companies
  • 787Products
  • 31Drugs by generic name

Drugs in the Antihistamine class

Ranked by number of companies that list the drug.

DrugProducts hereCompanies listing it
Acetaminophen3214
Hydroxyzine hydrochloride19151
Acetaminophen, dextromethorphan hbr, doxylamine succinate8340
Doxylamine succinate5339
Hydroxyzine pamoate8230
Benztropine mesylate5322
Dextromethorphan hbr122
Dextromethorphan hbr, doxylamine succinate1812
Dextromethorphan hydrobromide, doxylamine succinate119
Acetaminophen, dextromethorphan hbr and doxylamine succinate55
Acetaminophen, doxylamine succinate, dextromethorphan hbr55
Acetaminophen dextromethorphan hbr doxylamine succinate84
Doxylamine succinate and pyridoxine hydrochloride54
Hydroxyzine42
Acetaminophen, dextromethorphan, doxylamine succinate32
Dextromethorphan hbr doxylamine succinate22
Hydroxyzine hcl22
Nighttime sleep aid22
Benztropine31
Acetaminophen, dextromethrophan hbr, doxylamine succinate21
Acetaminophen, doxylamine succinate11
Acetaminophen, doxylamine succinate and dextromethorphan hbr11
Acetaminophen,dextromethorphan,doxylamine11
Acetaminophen,dextromethrophan hbr,doxylamine succinate11
Dextromethorphan hbr and doxylamine succinate11
Doxylamine succinate and phenylephrine hydrochloride11
Doxylamine succinate tablet11
Hydroxyzine hydrochloride oral11
Nightime cold and flu11
Nighttime cold and flu relief11
Nite time cold and flu relief11

Companies with the most products in this class

CompanyProductsMain dosage formsMain marketing categoryNewest product started
A-S Medication Solutions28tablet, film coated; tabletGeneric drugs (ANDA)August 22, 2023
Walgreen Company27liquid; solutionOver the counter monograph drugsApril 30, 2026
Bryant Ranch Prepack26tablet, film coated; capsuleGeneric drugs (ANDA)August 22, 2023
Remedyrepack Inc.19tablet; tablet, film coatedGeneric drugs (ANDA)August 30, 2025
CVS Woonsocket Prescription Center, Incorporated18solution; liquidOver the counter monograph drugsJuly 14, 2026
Lil' Drug Store Products, Inc.18tablet, coated; capsule, liquid filledOver the counter monograph drugsJuly 3, 2025
Amazon.com Services LLC16solution; tabletOver the counter monograph drugsSeptember 24, 2026
NuCare Pharmaceuticals,Inc.15tablet, film coated; capsuleGeneric drugs (ANDA)August 22, 2023
Chartwell RX, LLC14tablet; tablet, film coatedGeneric drugs (ANDA)August 20, 2014
The Procter & Gamble Manufacturing Company14liquid; capsule, liquid filledOver the counter monograph drugsJuly 9, 2024
Dolgencorp, Inc. (dollar General & Rexall)13solution; capsule, liquid filledOver the counter monograph drugsJune 30, 2025
Bryant Ranch Prepack12tablet, film coated; tabletGeneric drugs (ANDA)August 11, 2025
Coupler LLC12tablet; capsuleGeneric drugs (ANDA)August 31, 2026
The Procter & Gamble Manufacturing Company12liquid; capsule, liquid filledOver the counter monograph drugsAugust 17, 2026
Bayer HealthCare LLC.11capsule, liquid filled; tablet, effervescentOver the counter monograph drugsJune 1, 2026
Safeway11liquid; capsule, liquid filledOver the counter monograph drugsJune 10, 2026
HyVee Inc10solution; capsule, liquid filledOver the counter monograph drugsAugust 20, 2026
L. Perrigo Company10solution; tabletOver the counter monograph drugsJanuary 22, 2026
PD-Rx Pharmaceuticals, Inc.10tablet, film coated; capsuleGeneric drugs (ANDA)August 20, 2014
Proficient Rx LP10capsule; tablet, film coatedGeneric drugs (ANDA)March 31, 2015
Rite Aid Corporation10capsule, liquid filled; liquidOver the counter monograph drugsJuly 19, 2023
Aphena Pharma Solutions - Tennessee, LLC9tablet; capsuleGeneric drugs (ANDA)August 1, 2023
Topco Associates LLC9capsule, liquid filled; solutionOver the counter monograph drugsJuly 24, 2026
Bryant Ranch Prepack8tablet, film coated; capsuleGeneric drugs (ANDA)December 19, 2019
Chain Drug Marketing Association, Inc.8liquid; capsule, liquid filledOver the counter monograph drugsNovember 4, 2025
Major Pharmaceuticals8tablet; solutionGeneric drugs (ANDA)August 1, 2023
Meijer Distribution Inc8solution; tabletOver the counter monograph drugsMay 6, 2019
Meijer, Inc.8solution; capsule, liquid filledOver the counter monograph drugsJuly 22, 2026
NCS HealthCare of Ky, LLC DBA Vangard Labs8tablet; capsuleGeneric drugs (ANDA)March 17, 2022
Northwind Health Company, LLC8tablet; capsuleGeneric drugs (ANDA)April 25, 2023
Preferred Pharmaceuticals Inc.8tablet, film coated; capsuleGeneric drugs (ANDA)May 1, 2025
Wal-Mart Stores Inc8solution; tablet, film coatedOver the counter monograph drugsJuly 14, 2020
Target Corporation7liquid; capsule, liquid filledOver the counter monograph drugsJune 30, 2024
Topco Associates LLC7solution; capsule, liquid filledOver the counter monograph drugsSeptember 10, 2019
Asclemed USA, Inc.6tablet; capsuleGeneric drugs (ANDA)August 20, 2014
CVS Pharmacy6solution; capsule, liquid filledOver the counter monograph drugsDecember 4, 2020
Family Dollar (family Wellness)6liquid; capsule, liquid filledOver the counter monograph drugsJuly 31, 2024
H E B6solution; capsule, liquid filledOver the counter monograph drugsJune 20, 2022
Humanwell PuraCap Pharmaceutical (Wuhan), Ltd.6capsule, liquid filledOver the counter monograph drugsAugust 1, 2020
Kroger Company6liquid; capsule, liquid filledOver the counter monograph drugsApril 30, 2024
Kroger Company6solution; tabletOver the counter monograph drugsSeptember 9, 2023
Marlex Pharmaceuticals, Inc.6tablet, film coated; tabletGeneric drugs (ANDA)March 1, 2025
Opmx LLC6capsule, liquid filledOver the counter monograph drugsJuly 14, 2026
Sunrise Pharmaceutical, Inc.6tablet, film coated; tabletGeneric drugs (ANDA)October 16, 2024
Unit Dose Solutions, Inc.6capsule; tabletGeneric drugs (ANDA)July 8, 2026
United Natural Foods, Inc. DBA Unfi6solution; capsule, liquid filledOver the counter monograph drugsJuly 30, 2021
Walmart Inc.6solution; capsule, liquid filledOver the counter monograph drugsJuly 8, 2026
Advanced Rx of Tennessee, LLC5tablet, film coated; tabletGeneric drugs (ANDA)July 10, 2026
American Health Packaging5tablet, film coated; capsuleGeneric drugs (ANDA)September 11, 2025
American Sales Company5solution; tabletOver the counter monograph drugsOctober 22, 2018
AptaPharma Inc.5liquid; capsule, liquid filledOver the counter monograph drugsJanuary 1, 2026
Cardinal Health 110, LLC. DBA Leader5solution; tabletOver the counter monograph drugsAugust 2, 2024
Chain Drug Marketing Association5liquid; capsule, liquid filledOver the counter monograph drugsApril 30, 2021
Direct_Rx5capsule; tablet, film coatedGeneric drugs (ANDA)September 13, 2024
Golden State Medical Supply, Inc.5tablet; capsuleGeneric drugs (ANDA)August 20, 2014
Haleon US Holdings LLC5solution; capsule, liquid filledOver the counter monograph drugsJune 19, 2024
L.N.K. International, Inc.5solution; tabletOver the counter monograph drugsFebruary 7, 2022
Pharmadel LLC5capsule, liquid filled; liquidOver the counter monograph drugsApril 1, 2026
Publix Super Markets Inc5solution; tabletOver the counter monograph drugsMay 16, 2025
Softgel Healthcare Pvt Ltd5capsule, liquid filledOver the counter monograph drugsJune 11, 2025
Advanced Rx LLC4capsule, liquid filled; tabletOver the counter monograph drugsJanuary 1, 2025
Amerisource Bergen4solution; capsule, liquid filledOver the counter monograph drugsJune 7, 2024
CVS Pharmacy4solution; tabletOver the counter monograph drugsDecember 27, 2013
Discount Drug Mart4liquid; capsule, liquid filledOver the counter monograph drugsNovember 8, 2023
Grocery Outlet, Inc.4liquid; tabletOver the counter monograph drugsMarch 25, 2026
Kenvue Brands LLC4liquid; capsule, liquid filledOver the counter monograph drugsJune 1, 2026
P & L Development, LLC4liquidOver the counter monograph drugsMarch 26, 2021
PD-Rx Pharmaceuticals, Inc.4tablet, film coated; tabletGeneric drugs (ANDA)August 20, 2014
Proficient Rx LP4tablet; syrupGeneric drugs (ANDA)August 20, 2014
Shield Pharmaceuticals Corp4capsule, liquid filledOver the counter monograph drugsSeptember 2, 2026
Strategic Sourcing Services LLC4solution; tabletOver the counter monograph drugsOctober 31, 2023
The Procter & Gamble Manufacturing Company4solution; capsule, liquid filledOver the counter monograph drugsAugust 1, 2018
WinCo Foods, LLC4capsule, liquid filled; liquidOver the counter monograph drugsOctober 29, 2021
American Health Packaging3tabletGeneric drugs (ANDA)July 1, 2013
American Regent, Inc.3injection, solutionGeneric drugs (ANDA)September 30, 1990
Amneal Pharmaceuticals LLC3tablet, film coatedGeneric drugs (ANDA)September 24, 2008
Army and Air Force Exchange Service3tablet; solutionOver the counter monograph drugsJanuary 1, 2025
Aurobindo Pharma Limited3tablet, film coatedGeneric drugs (ANDA)October 7, 2021
Bi-Mart3tablet; capsule, liquid filledOver the counter monograph drugsJune 1, 2025
Camber Pharmaceuticals, Inc.3tablet, film coatedGeneric drugs (ANDA)May 29, 2008
Cipla USA Inc.3tabletGeneric drugs (ANDA)June 29, 2016
Epic Pharma, LLC3tablet, film coatedGeneric drugs (ANDA)March 31, 2015
Harris Teeter, LLC3liquid; capsule, liquid filledOver the counter monograph drugsMay 28, 2021
Heritage Pharmaceuticals Inc. D/B/A Avet Pharmaceuticals Inc.3tabletGeneric drugs (ANDA)August 20, 2014
KVK-Tech, Inc.3tablet, film coatedGeneric drugs (ANDA)July 24, 2012
Leading Pharma, LLC3tabletGeneric drugs (ANDA)November 28, 2012
NorthStar Rx LLC3tabletGeneric drugs (ANDA)November 11, 2009
Par Health USA, LLC3tabletGeneric drugs (ANDA)March 17, 2022
PuraCap Pharmaceutical LLC3capsule, liquid filledOver the counter monograph drugsMarch 12, 2025
Puracap Laboratories LLC DBA Blu Pharmaceuticals3tablet, film coatedGeneric drugs (ANDA)July 21, 2021
Quagen Pharmaceuticals LLC3tabletGeneric drugs (ANDA)August 11, 2025
Raritan Pharmaceuticals Inc3solution; capsule, liquid filledOver the counter monograph drugsDecember 1, 2025
Rising Pharma Holdings, Inc.3tablet, film coatedGeneric drugs (ANDA)August 22, 2023
Salado Sales, Inc.3liquid; capsule, liquid filledOver the counter monograph drugsDecember 23, 2025
ScieGen Pharmaceuticals, Inc.3tabletGeneric drugs (ANDA)November 5, 2024
St. Mary's Medical Park Pharmacy3tablet, film coatedGeneric drugs (ANDA)March 19, 2025
Teva Pharmaceuticals USA, Inc.3tablet, film coatedGeneric drugs (ANDA)February 19, 2013
Teva Pharmaceuticals USA, Inc.3capsuleGeneric drugs (ANDA)July 1, 1984
Valu Merchandisers Company3liquidOver the counter monograph drugsJanuary 31, 2018
Vivunt Pharma LLC3liquid; capsule, liquid filledOver the counter monograph drugsMay 14, 2024

Dosage forms

Dosage formProductsShare
Tablet16320.7%
Solution13517.2%
Tablet, film coated12816.3%
Capsule, liquid filled12115.4%
Liquid10012.7%
Capsule8811.2%
Tablet, coated131.7%
Tablet, delayed release70.9%
Injection, solution70.9%
Syrup70.9%
Injection40.5%
Tablet, chewable30.4%

Updated November 6, 2026. Read from US Food and Drug Administration, National Drug Code Directory (openFDA). CC0 1.0 public domain dedication (openFDA). Counts are products in the FDA National Drug Code Directory on November 6, 2026: 138,262 products in commercial distribution, meaning without a marketing end date in the past. A company is a labeler code; one company can hold several codes, and the directory carries no address. Inclusion in the directory is not FDA approval, and the marketing category says under which kind of application or rule a product is sold. This page uses openFDA data and is not endorsed or certified by FDA. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.