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Data / Drug companies / Amide Local Anesthetic

Amide Local Anesthetic drugs: 303 drugs from 527 companies in the FDA NDC directory

Amide Local Anesthetic is an FDA established pharmacologic class. The FDA National Drug Code Directory lists 2,076 products in this class from 527 companies, covering 303 drugs by generic name. The main marketing category is over the counter monograph drugs, and the newest product started marketing on November 4, 2026.

SpecStream is the live web data engine for teams and agents. It reads the National Drug Code Directory that FDA publishes, and this page is that reading. Ask for the companies that make a drug, a class or a dosage form, with their headquarters, website and size added from the web, and new listings and discontinued products arrive in your sheet, CRM, Slack or agent as FDA posts them.

  • 527Companies
  • 2,076Products
  • 303Drugs by generic name

Drugs in the Amide Local Anesthetic class

Ranked by number of companies that list the drug.

DrugProducts hereCompanies listing it
Menthol1263
Lidocaine477216
Lidocaine hydrochloride386134
Lidocaine hcl7848
Lidocaine 4%7345
Lidocaine, menthol5434
Bupivacaine hydrochloride10323
Lidocaine 5%4023
Ropivacaine hydrochloride7920
Benzalkonium chloride, lidocaine hydrochloride2318
Lidocaine and menthol3417
Lidocaine hcl, menthol1817
Lidocaine and prilocaine1814
Lidocaine hydrochloride, menthol1714
Mepivacaine hydrochloride159
Benzalkonium chloride and lidocaine hydrochloride99
Lidocaine hydrochloride and epinephrine bitartrate128
Lidocaine hci217
Benzalkonium chloride, lidocaine157
Lidocaine, phenylephrine hydrochloride97
Lidocaine hydrochloride and epinephrine236
Lidocaine hcl 4%96
Bupivacaine hydrochloride and epinephrine bitartrate155
Articaine hydrochloride and epinephrine145
Articaine hydrochloride and epinephrine bitartrate105
Lidocaine hydrochloride,epinephrine bitartrate105
Lidocaine pain relief patch95
Glycerin, lidocaine, petrolatum, phenylephrine hcl55
Lidocaine and capsaicin55
Lidocaine hcl 4%, menthol 1%55
5% lidocaine134
Benzalkonium chloride, lidocaine hci94
Lidocaine hydrochloride, benzalkonium chloride84
Lidocaine hydrochloride anhydrous64
Benzalkonium chloride, lidocaine hcl54
Lidocaine 4%, menthol 1%44
4% lidocaine73
Numbing cream63
Lidocaine hcl and menthol53
Benzethonium chloride and lidocaine43
Benzyl alcohol, lidocaine hydrochloride43
Lidocaine hydrochloride, benzyl alcohol43
Lidocaine, phenylephrine hcl43
Burn relief33
Capsaicin and lidocaine33
Lidocaine 4.5%, diclofenac 1%33
Lidocaine and camphor33
Lidocaine and menthol patch33
Lidocaine hcl, benzalkonium chloride33
Lidocaine pain relief33
Menthol 5%, lidocaine 4%33
Pain relief cream13
Lidocaine patch 4%82
Lidocaine hydrochloride and benzalkonium chloride62
Lidocaine hydrochloride and hydrocortisone acetate52
Lidocaine pain relief gel-patch52
Bupivacaine42
Lidocaine hcl and epinephrine32
Lidocaine hydrochloride anhydrous and dextrose monohydrate32
4% lidocaine hcl22
Alcohol, lidocaine hydrochloride22
Benzalkonium chloride 0.13%(w/w)/lidocaine hcl 4.0%(w/w)22
Benzalkonium cl, lidocaine hcl22
Benzyl alcohol and lidocaine hydrochloride22
Lidicaine22
Lidocaine 5%, phenylephrine hydrochloride 0.25%22
Lidocaine hcl 0.5%22
Lidocaine hydrochloride and menthol, unspecified form22
Lidocaine hydrochloride,benzalkonium chloride22
Lidocaine patch22
Lidocaine, menthol, and methyl salicylate22
Lidocaine, phenylephrine22
Menthol and lidocaine22
Numbing22
Numbing lubricant22
Prilocaine hcl and epinephrine22
First aid antiseptic12
Glycerol, phenylephine, pramoxine, petrolatum12
Bupivacaine hydrochloride and epinephrine101
Lidocaine cream61
Lidocaine hcl and hydrocortisone acetate51
Lidocaine 4% phenylephrine hcl 0.25% hemorrhoid41
Lidocaine4% numbing41
Xylocaine41
2% lidocaine hci31
4% lidocaine patches31
Lidocaine hci and epinephrine31
Lidocaine hcl, phenol31
Lidocaine hydrochloride, menthol,magnesium chloride31
Lidocarine31
1% lidocaine hci21
5% lidocaine cream21
Anorectal21
Articaine hydrochloride, epinephrine bitartrate21
Benzalkonium chloride, lidocain hydrochloride21
Bupivacaine and meloxicam21
Bupivacaine hcl21
Bupivacaine hydrochloride in dextrose21
Burn ease21
Burn ease 3.5g21

Companies with the most products in this class

CompanyProductsMain dosage formsMain marketing categoryNewest product started
Fresenius Kabi USA, LLC57injection, solutionNew drug applications (NDA)July 18, 2011
HF Acquisition Co LLC, DBA HealthFirst56injection, solution; jellyGeneric drugs (ANDA)September 15, 2022
Hospira, Inc.48injection, solutionGeneric drugs (ANDA)August 28, 2025
Veridian Healthcare45patch; creamOver the counter monograph drugsApril 1, 2026
Henry Schein, Inc.39injection, solution; jellyGeneric drugs (ANDA)June 24, 2026
Walgreen Company39patch; creamOver the counter monograph drugsMarch 27, 2026
Eugia US LLC38injection, solutionGeneric drugs (ANDA)October 30, 2017
PureTek Corporation36cream; gelOther unapproved drugsSeptember 19, 2025
Asclemed USA, Inc.28injection, solution; patchGeneric drugs (ANDA)April 1, 2025
Advanced Rx of Tennessee, LLC26ointment; patchGeneric drugs (ANDA)September 10, 2026
Hikma Pharmaceuticals USA Inc.24injection, solution; injectionGeneric drugs (ANDA)November 18, 2025
Medical Purchasing Solutions, LLC23injection, solution; injectionGeneric drugs (ANDA)July 1, 2025
Guangzhou Liuquanmiao Import & Export Trade Co., Ltd.21patch; gelOver the counter monograph drugsAugust 21, 2026
Jiangxi Yudexi Pharmaceutical Co., LTD21cream; patchOver the counter monograph drugsMay 26, 2026
Chattem, Inc.20cream; liquidOver the counter monograph drugsJuly 21, 2026
Preferred Pharmaceuticals Inc.20patch; ointmentGeneric drugs (ANDA)September 24, 2026
Sportpharm LLC18injection, solution; patchGeneric drugs (ANDA)February 6, 2026
CVS Woonsocket Prescription Center, Incorporated17cream; patchOver the counter monograph drugsApril 6, 2026
Derma Care Research Labs, LLC17cream; sprayOver the counter monograph drugsMay 30, 2023
Nantong Health & Beyond Hygienic Products Inc.17cream; gelOver the counter monograph drugsAugust 13, 2026
Shanghai Chuangshi Medical Technology (Group) Co., Ltd.17patch; gelOver the counter monograph drugsOctober 8, 2026
Shengnan (Guangzhou) Cosmetics Co., LTD17creamOver the counter monograph drugsApril 13, 2026
Planet (Anhui) Pharmaceutical Co., Ltd.16patch; tapeOver the counter monograph drugsJuly 1, 2026
Trifecta Pharmaceuticals USA LLC16cream; sprayOver the counter monograph drugsApril 27, 2026
A-S Medication Solutions15injection, solution; patchGeneric drugs (ANDA)January 1, 2025
NorthStar RxLLC15injection, solutionGeneric drugs (ANDA)February 1, 2025
Yyba Corp15cream; patchOver the counter monograph drugsNovember 2, 2026
Direct_Rx14ointment; patchGeneric drugs (ANDA)September 28, 2026
Guangzhou Zhupuyou E-commerce Co., Ltd14patch; gelOver the counter monograph drugsNovember 19, 2025
Sambria Pharmaceuticals, LLC14cream; liquidOver the counter monograph drugsJuly 10, 2025
Unifirst First Aid Corporation14cream; sprayOver the counter monograph drugsApril 1, 2023
Henan Enokon Medical Instrument Co., Ltd.13patch; sprayOver the counter monograph drugsSeptember 1, 2026
ProPharma Distribution13injection, solution; injectionGeneric drugs (ANDA)May 1, 2024
Septodont, Inc.13injection, solution; ointmentGeneric drugs (ANDA)March 19, 2026
Anthea Pharma Private Limited12injection, solutionGeneric drugs (ANDA)April 22, 2026
CVS Pharmacy12gel; sprayOver the counter monograph drugsJanuary 1, 2022
Lifestar Pharma LLC12injection, solutionGeneric drugs (ANDA)November 29, 2023
Oncora Pharma, LLC12gel; sprayOther unapproved drugsOctober 22, 2026
Meijer, Inc.11patch; liquidOver the counter monograph drugsFebruary 28, 2025
Novocol Pharmaceutical of Canada, Inc.11injection, solutionAuthorized generics (NDA)March 18, 2019
ProStat First Aid11gel; creamOver the counter monograph drugsJanuary 13, 2026
Prodigy Media Inc11cream; sprayOver the counter monograph drugsMay 1, 2026
Proficient Rx LP11ointment; patchGeneric drugs (ANDA)September 1, 2022
Remedyrepack Inc.11ointment; patchGeneric drugs (ANDA)October 14, 2025
Clarion Brands, LLC10liquid; sprayOver the counter monograph drugsApril 20, 2026
Guangzhou Jingliang Cosmetics Co., Ltd.10creamOver the counter monograph drugsSeptember 17, 2026
Walmart Inc.10patch; creamOver the counter monograph drugsApril 1, 2026
Cardinal Health 110, LLC. DBA Leader9patch; creamOver the counter monograph drugsAugust 21, 2025
Meitheal Pharmaceuticals Inc.9injection, solutionGeneric drugs (ANDA)July 30, 2024
Somerset Therapeutics, LLC9injection; injection, solutionGeneric drugs (ANDA)November 27, 2023
Telebrands Corp9cream; patchOver the counter monograph drugsNovember 21, 2024
100 Karma Inc8cream; patchOver the counter monograph drugsFebruary 25, 2026
Bryant Ranch Prepack8patch; ointmentGeneric drugs (ANDA)December 5, 2022
Cardinal Health 107, LLC8injection, solution; patchGeneric drugs (ANDA)April 1, 2019
Clinical Resolution Laboratory, Inc.8cream; sprayOver the counter monograph drugsMay 14, 2025
Dentsply Pharmaceutical8injection, solution; gelGeneric drugs (ANDA)December 4, 2017
Ebanel Laboratories, Inc8cream; liquidOver the counter monograph drugsJune 6, 2025
InterMed Laboratories Private Limited8patchOver the counter monograph drugsNovember 6, 2025
Meijer Distribution Inc8patch; creamOver the counter monograph drugsApril 20, 2020
Onesource Specialty Pharma Limited8injection, solutionGeneric drugs (ANDA)January 29, 2026
Sola Pharmaceuticals, LLC8patch; injection, solutionOver the counter monograph drugsDecember 1, 2024
Transfer Technology8patchOver the counter monograph drugsAugust 13, 2026
WellSpring Pharmaceutical Corporation8liquid; sprayOver the counter monograph drugsNovember 15, 2024
Xellia Pharmaceuticals USA LLC8injection, solutionGeneric drugs (ANDA)August 1, 2023
Acme United Corporation7cream; gelOver the counter monograph drugsOctober 1, 2026
Asclemed USA Inc.7patch; ointmentOther unapproved drugsMay 5, 2026
Blue Heron Pharmaceuticals, LLC7patchOver the counter monograph drugsNovember 4, 2026
Bryant Ranch Prepack7solution; ointmentGeneric drugs (ANDA)November 1, 2024
Camber Pharmaceuticals, Inc.7injection, solutionGeneric drugs (ANDA)March 27, 2024
EveryMarket Inc7creamOver the counter monograph drugsJuly 29, 2026
Guangdong Aimu Biological Technology Co., Ltd7cream; gelOver the counter monograph drugsJuly 31, 2026
Kenvue Brands LLC7cream; patchOver the counter monograph drugsJune 16, 2025
Natural Essentials, Inc.7patch; creamOver the counter monograph drugsApril 23, 2021
Phoenix RX LLC7ointment; patchGeneric drugs (ANDA)October 3, 2023
Quest Products, Inc.7gel; sprayOver the counter monograph drugsFebruary 23, 2024
Rite Aid Corporation7patch; liquidOver the counter monograph drugsAugust 1, 2024
V2 Pharma, LLC7cream; patchOver the counter monograph drugsOctober 28, 2026
Amerisource Bergen6patch; aerosol, sprayOver the counter monograph drugsAugust 1, 2025
Baxter Healthcare Corporation6injection; injection, solutionGeneric drugs (ANDA)January 1, 2024
Brookfield Pharmaceuticals, LLC.6solution; injectionGeneric drugs (ANDA)November 27, 2025
Caplin Steriles Limited6injectionGeneric drugs (ANDA)June 24, 2025
Clinic Pharma6gel; patchOther unapproved drugsMarch 11, 2026
Glenmark Pharmaceuticals Inc., USA6injection, solution; ointmentGeneric drugs (ANDA)October 8, 2025
International Medication Systems, Limited6jelly; solutionGeneric drugs (ANDA)June 19, 2012
Little Pharma, Inc.6cream; patchOver the counter monograph drugsOctober 9, 2026
NuCare Pharmaceuticals,Inc.6cream; solutionGeneric drugs (ANDA)June 15, 2023
Rapid Aid Viet Nam Company Limited6patchOver the counter monograph drugsMarch 10, 2026
Safeway6patch; gelOver the counter monograph drugsOctober 1, 2025
Scalp Tech Inc6spray; gelOver the counter monograph drugsAugust 7, 2026
Shinpharma Inc6creamOver the counter monograph drugsFebruary 27, 2025
Skins Sexual Health Limited6solutionOver the counter monograph drugsOctober 3, 2022
Trifluent Pharma, LLC6patch; creamGeneric drugs (ANDA)January 9, 2026
Unit Dose, Ltd.6ointment; sprayOver the counter monograph drugsJanuary 22, 2016
Water-Jel Technologies6gel; sprayOver the counter monograph drugsOctober 28, 2019
B. Braun Medical Inc.5injection; injection, solutionGeneric drugs (ANDA)September 8, 2021
Benco Dental5injection, solutionGeneric drugs (ANDA)April 4, 2016
Bryant Ranch Prepack5patch; creamGeneric drugs (ANDA)December 20, 2022
Esba Laboratories Inc.5gel; creamOver the counter monograph drugsSeptember 3, 2019
Ferndale Laboratories, Inc.5cream; clothOver the counter monograph drugsApril 1, 2016
Guangzhou Haishi Biological Technology Co., Ltd.5creamOver the counter monograph drugsOctober 21, 2025

Dosage forms

Dosage formProductsShare
Cream48823.5%
Injection, solution47723%
Patch42920.7%
Gel1858.9%
Spray1165.6%
Liquid1004.8%
Ointment994.8%
Solution623%
Injection442.1%
Aerosol, spray170.8%
Jelly150.7%
Lotion120.6%

Updated November 6, 2026. Read from US Food and Drug Administration, National Drug Code Directory (openFDA). CC0 1.0 public domain dedication (openFDA). Counts are products in the FDA National Drug Code Directory on November 6, 2026: 138,262 products in commercial distribution, meaning without a marketing end date in the past. A company is a labeler code; one company can hold several codes, and the directory carries no address. Inclusion in the directory is not FDA approval, and the marketing category says under which kind of application or rule a product is sold. This page uses openFDA data and is not endorsed or certified by FDA. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.