Data / Drug companies / alpha-Adrenergic Agonist
alpha-Adrenergic Agonist drugs: 91 drugs from 211 companies in the FDA NDC directory
alpha-Adrenergic Agonist is an FDA established pharmacologic class. The FDA National Drug Code Directory lists 926 products in this class from 211 companies, covering 91 drugs by generic name. The main marketing category is generic drugs (ANDA), and the newest product started marketing on October 26, 2026.
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- 211Companies
- 926Products
- 91Drugs by generic name
Drugs in the alpha-Adrenergic Agonist class
Ranked by number of companies that list the drug.
| Drug | Products here | Companies listing it |
|---|---|---|
| Lidocaine hydrochloride | 1 | 134 |
| Midodrine hydrochloride | 109 | 34 |
| Epinephrine | 107 | 32 |
| Pseudoephedrine hcl | 42 | 29 |
| Ephedrine sulfate | 41 | 26 |
| Pseudoephedrine hydrochloride | 39 | 23 |
| Cetirizine hydrochloride, pseudoephedrine hydrochloride | 20 | 18 |
| Fexofenadine hydrochloride and pseudoephedrine hydrochloride | 24 | 16 |
| Brimonidine tartrate | 28 | 15 |
| Guaifenesin and pseudoephedrine hydrochloride | 23 | 15 |
| Loratadine, pseudoephedrine sulfate | 21 | 15 |
| Loratadine and pseudoephedrine sulfate | 19 | 15 |
| Guaifenesin and pseudoephedrine hcl | 23 | 14 |
| Brimonidine tartrate and timolol maleate | 20 | 14 |
| Cetirizine hydrochloride and pseudoephedrine hydrochloride | 11 | 10 |
| Lidocaine hydrochloride and epinephrine bitartrate | 12 | 8 |
| Guaifenesin, pseudoephedrine hydrochloride | 8 | 8 |
| Fexofenadine hcl and pseudoephedrine hci | 9 | 7 |
| Loratadine and pseudoephedrine | 8 | 7 |
| Lidocaine hci | 1 | 7 |
| Lidocaine hydrochloride and epinephrine | 23 | 6 |
| Ibuprofen and pseudoephedrine hydrochloride | 7 | 6 |
| Bupivacaine hydrochloride and epinephrine bitartrate | 15 | 5 |
| Articaine hydrochloride and epinephrine | 14 | 5 |
| Articaine hydrochloride and epinephrine bitartrate | 10 | 5 |
| Lidocaine hydrochloride,epinephrine bitartrate | 10 | 5 |
| Ibuprofen and pseudoephedrine hcl | 5 | 5 |
| Fexofenadine hydrochloride, pseudoephedrine hydrochloride | 4 | 4 |
| Naproxen sodium, pseudoephedrine hcl | 4 | 4 |
| Naproxen sodium and pseudoephedrine hydrochloride | 4 | 3 |
| Naproxen sodium, pseudoephedrine hydrochloride | 3 | 3 |
| Pseudoephedrine hcl, triprolidine hcl | 3 | 3 |
| Dexbrompheniramine maleate, pseudoephedrine hcl | 3 | 2 |
| Lidocaine hcl and epinephrine | 3 | 2 |
| Adrenalinum | 2 | 2 |
| Brimonidine | 2 | 2 |
| Brimonidine tartrate ophthalmic solution, 0.15% | 2 | 2 |
| Chlorpheniramine maleate, pseudoephedrine hcl | 2 | 2 |
| Ephedrine hydrochloride | 2 | 2 |
| Prilocaine hcl and epinephrine | 2 | 2 |
| Bupivacaine hydrochloride and epinephrine | 10 | 1 |
| Epinephrine in sodium chloride | 5 | 1 |
| Auvi-q | 3 | 1 |
| Brimonidine tartrate ophthalmic solution | 3 | 1 |
| Dexbrompheniramine maleate, pseudoephedrine hydrochloride | 3 | 1 |
| Dextromethorphan, guiafenesin, pseudoephedrine hcl | 3 | 1 |
| Lidocaine hci and epinephrine | 3 | 1 |
| Articaine hydrochloride, epinephrine bitartrate | 2 | 1 |
| Chlorpheniramine maleate / pseudoephedrine hcl | 2 | 1 |
| Dextromethorphan hbr,guaifenesin,pseudoephedrine hcl | 2 | 1 |
| Epinephrine 0.15 pediatrics | 2 | 1 |
| Epinephrine 0.3 adults | 2 | 1 |
| Epinephrine hydrochloride, lidocaine hydrochloride | 2 | 1 |
| Epinephrine inhalation | 2 | 1 |
| Lidocaine hydrochloride, epinephrine hydrochloride | 2 | 1 |
| Acetaminophen, dextromethorphan hbr, pseudoephedrine hcl | 1 | 1 |
| Acetaminophen, pseudoephedrine | 1 | 1 |
| Adrenalin (epinephrine) | 1 | 1 |
| Adrenalin(r) | 1 | 1 |
| Apraclonidine | 1 | 1 |
| Apraclonidine hydrochloride | 1 | 1 |
| Apraclonidine hydrochloride ophthalmic solution | 1 | 1 |
| Brimonidine tartrate, timolol maleate | 1 | 1 |
| Brinzolamide/brimonidine tartrate | 1 | 1 |
| Brompheniramine maleate and pseudoephedrine hydrochloride | 1 | 1 |
| Brompheniramine maleate, pseudoephedrine hydrochloride, | 1 | 1 |
| Brompheniramine, pseudoephedrine, dextromethorphan | 1 | 1 |
| Bupivacaine hci and epinephrine | 1 | 1 |
| Carbachol and brimonidine tartrate | 1 | 1 |
| Chlorpheniramine maleate, ibuprofen, pseudoephedrine hcl | 1 | 1 |
| Desloratadine and pseudoephedrine sulfate | 1 | 1 |
| Dextromethorphan hbr, guaifenesin and pseudoephedrine hcl | 1 | 1 |
| Dextromethorphan hbr, pseufoephedrine hcl, triprolidine hcl | 1 | 1 |
| Epinephrine hydrochloride | 1 | 1 |
| Epineprine | 1 | 1 |
| Guaifenesin 600 mg and pseudoephedrine hcl 60 mg | 1 | 1 |
| Guaifenesin, pseudoephedrine hcl | 1 | 1 |
| Ibuprofen, pseudoephedrine hydrochloride | 1 | 1 |
| Lidocaine hci and epinephrine with epinephrine | 1 | 1 |
| Lidocaine hydrochloride and epinephrine hydrochloride | 1 | 1 |
| Lidocaine, epinephrine | 1 | 1 |
| Loratadine pseudoephedrine sulfate | 1 | 1 |
| Naproxen sodium, pseudeoephedrine hydrochloride | 1 | 1 |
| Numbing spray | 1 | 1 |
| Pseudoephedrine hcl, pyrilamine maleate | 1 | 1 |
| Sensorcaine(r) (bupivacaine hci and epinephrine) | 1 | 1 |
| Tattoo cream | 1 | 1 |
| Tattoo numbing spray | 1 | 1 |
| Xylocaine | 1 | 1 |
| Xylocaine(r) -mpf (lidocaine hci and epinephrine) | 1 | 1 |
| Xylocaine-mpf with epi | 1 | 1 |
Companies with the most products in this class
| Company | Products | Main dosage forms | Main marketing category | Newest product started |
|---|---|---|---|---|
| HF Acquisition Co LLC, DBA HealthFirst | 29 | injection, solution; injection | New drug applications (NDA) | June 8, 2026 |
| Walgreen Company | 28 | tablet, extended release; tablet, film coated, extended release | Generic drugs (ANDA) | August 27, 2026 |
| Deseret Biologicals, Inc. | 27 | liquid | Unapproved homeopathic products | March 20, 2026 |
| Hospira, Inc. | 22 | injection, solution | Generic drugs (ANDA) | October 28, 2024 |
| Newton Laboratories, Inc. | 19 | liquid; pellet | Unapproved homeopathic products | July 3, 2023 |
| Major Pharmaceuticals | 18 | tablet; tablet, film coated | Over the counter monograph drugs | September 15, 2026 |
| Medical Purchasing Solutions, LLC | 18 | injection; injection, solution | New drug applications (NDA) | August 9, 2024 |
| A-S Medication Solutions | 17 | tablet, film coated; injection | New drug applications (NDA) | January 30, 2023 |
| Sportpharm LLC | 17 | injection, solution; injection | Generic drugs (ANDA) | March 5, 2025 |
| Fresenius Kabi USA, LLC | 16 | injection, solution; injection, solution, concentrate | New drug applications (NDA) | March 13, 2025 |
| Henry Schein, Inc. | 16 | injection, solution; injection | New drug applications (NDA) | February 17, 2025 |
| Cardinal Health 110, LLC. DBA Leader | 14 | tablet, film coated, extended release; tablet, multilayer, extended release | Generic drugs (ANDA) | August 3, 2026 |
| Kroger Company | 14 | tablet, film coated, extended release; tablet, extended release | Generic drugs (ANDA) | January 16, 2026 |
| Par Health USA, LLC | 13 | injection; injection, solution | New drug applications (NDA) | May 19, 2025 |
| NaturalCare | 12 | liquid; tablet | Unapproved homeopathic products | May 14, 2026 |
| Strategic Sourcing Services LLC | 12 | tablet, film coated, extended release; tablet, extended release | Generic drugs (ANDA) | February 11, 2026 |
| Aurohealth LLC | 11 | tablet, extended release; tablet, film coated, extended release | Generic drugs (ANDA) | December 29, 2025 |
| CVS Woonsocket Prescription Center, Incorporated | 11 | tablet, film coated, extended release; tablet, extended release | Generic drugs (ANDA) | January 20, 2026 |
| Gland Pharma Limited | 11 | injection; solution/ drops | Generic drugs (ANDA) | October 26, 2026 |
| L. Perrigo Company | 11 | tablet, film coated, extended release; tablet, multilayer, extended release | Generic drugs (ANDA) | October 3, 2025 |
| Nutritional Specialties, Inc. | 10 | liquid; spray | Unapproved homeopathic products | February 23, 2026 |
| Professional Complementary Health Formulas | 10 | liquid | Unapproved homeopathic products | August 15, 1984 |
| Rite Aid Corporation | 10 | tablet, extended release; tablet, film coated, extended release | Generic drugs (ANDA) | July 20, 2023 |
| Septodont, Inc. | 10 | injection, solution | Generic drugs (ANDA) | March 19, 2026 |
| Somerset Therapeutics, LLC | 10 | solution/ drops; injection | Generic drugs (ANDA) | November 7, 2024 |
| CVS Pharmacy | 9 | tablet, extended release; tablet, film coated, extended release | Generic drugs (ANDA) | December 28, 2022 |
| Carolinas Weight Loss Institute | 9 | spray | Unapproved homeopathic products | January 29, 2026 |
| Novocol Pharmaceutical of Canada, Inc. | 9 | injection, solution | Authorized generics (NDA) | March 18, 2019 |
| Ohm Laboratories Inc. | 9 | tablet, extended release; tablet, film coated, extended release | Generic drugs (ANDA) | April 1, 2021 |
| Remedyrepack Inc. | 9 | injection; syrup | Generic drugs (ANDA) | February 11, 2026 |
| Amerisource Bergen | 8 | tablet, film coated, extended release; tablet, extended release | Generic drugs (ANDA) | October 1, 2024 |
| Bryant Ranch Prepack | 8 | tablet; syrup | Generic drugs (ANDA) | October 15, 2020 |
| Bryant Ranch Prepack | 8 | tablet; syrup | Generic drugs (ANDA) | January 1, 2023 |
| H E B | 8 | tablet, film coated, extended release; tablet, extended release | Generic drugs (ANDA) | May 27, 2025 |
| Kenvue Brands LLC | 8 | tablet, film coated; tablet, film coated, extended release | Over the counter monograph drugs | June 10, 2026 |
| NorthStar RxLLC | 8 | tablet; injection | Generic drugs (ANDA) | June 15, 2026 |
| Publix Super Markets Inc | 8 | tablet, film coated, extended release; tablet, sugar coated | Generic drugs (ANDA) | April 2, 2026 |
| Lifestar Pharma LLC | 7 | tablet; solution/ drops | Generic drugs (ANDA) | June 1, 2026 |
| Meijer Distribution Inc | 7 | tablet, film coated, extended release; tablet, film coated | Generic drugs (ANDA) | April 7, 2020 |
| Actipharma, LLC | 6 | solution; tablet | Over the counter monograph drugs | July 17, 2025 |
| Alembic Pharmaceuticals Inc. | 6 | solution/ drops; tablet | Generic drugs (ANDA) | August 25, 2023 |
| Alembic Pharmaceuticals Limited | 6 | tablet; solution/ drops | Generic drugs (ANDA) | August 25, 2023 |
| Apotex Corp. | 6 | tablet; solution/ drops | Generic drugs (ANDA) | September 2, 2023 |
| Bpi Labs LLC | 6 | injection; injection, solution, concentrate | New drug applications (NDA) | March 21, 2024 |
| Llorens Pharmaceutical International Division, Inc. | 6 | liquid; solution/ drops | Over the counter monograph drugs | December 1, 2024 |
| Natural Creations, Inc | 6 | liquid | Unapproved homeopathic products | February 11, 2020 |
| ProPharma Distribution | 6 | injection; injection, solution | New drug applications (NDA) | January 30, 2023 |
| Rugby Laboratories | 6 | tablet, extended release; tablet, film coated, extended release | Generic drugs (ANDA) | October 12, 2026 |
| Topco Associates LLC | 6 | tablet, film coated, extended release; tablet, extended release | Generic drugs (ANDA) | August 16, 2023 |
| Asclemed USA, Inc. | 5 | injection | Authorized generics (NDA) | November 27, 2018 |
| BioActive Nutritional, Inc. | 5 | liquid | Unapproved homeopathic products | April 30, 2020 |
| CVS Pharmacy | 5 | tablet, film coated, extended release; tablet, film coated | Generic drugs (ANDA) | November 19, 2014 |
| Cardinal Health 107, LLC | 5 | tablet; injection, solution | Generic drugs (ANDA) | April 5, 2010 |
| Dentsply Pharmaceutical | 5 | injection, solution | Generic drugs (ANDA) | December 4, 2017 |
| Glenmark Pharmaceuticals Inc., USA | 5 | injection; injection, solution, concentrate | Generic drugs (ANDA) | September 22, 2026 |
| Padagis Israel Pharmaceuticals Ltd | 5 | tablet, film coated, extended release; gel | Generic drugs (ANDA) | January 1, 2023 |
| Poly Pharmaceuticals, Inc. | 5 | tablet; liquid | Over the counter monograph drugs | October 15, 2025 |
| Safeway | 5 | tablet, film coated, extended release; tablet, film coated | Generic drugs (ANDA) | September 1, 2023 |
| Sina Health Inc | 5 | injection | Authorized generics (NDA) | December 15, 2016 |
| Wal-Mart Stores Inc | 5 | tablet, extended release; tablet, film coated, extended release | Generic drugs (ANDA) | July 24, 2020 |
| Walmart Inc. | 5 | tablet, film coated, extended release; tablet, multilayer, extended release | Generic drugs (ANDA) | August 6, 2026 |
| Apex Energetics Inc. | 4 | solution/ drops | Unapproved homeopathic products | July 15, 1997 |
| Benco Dental | 4 | injection, solution | Generic drugs (ANDA) | April 4, 2016 |
| Bryant Ranch Prepack | 4 | tablet | Generic drugs (ANDA) | August 10, 2020 |
| Caplin Steriles Limited | 4 | solution; injection | Generic drugs (ANDA) | March 10, 2025 |
| Costco Wholesale Company | 4 | tablet, film coated, extended release; tablet, extended release | Generic drugs (ANDA) | October 3, 2025 |
| Dr. Reddy's Laboratories Limited | 4 | tablet, extended release | Generic drugs (ANDA) | December 29, 2017 |
| Energique, Inc. | 4 | liquid | Unapproved homeopathic products | January 28, 2025 |
| Guna Spa | 4 | solution/ drops; pellet | Unapproved homeopathic products | September 24, 2020 |
| Haleon US Holdings LLC | 4 | tablet, coated; capsule, liquid filled | New drug applications (NDA) | January 1, 2018 |
| Proficient Rx LP | 4 | syrup; tablet, extended release | Generic drugs (ANDA) | September 21, 2016 |
| Proficient Rx LP | 4 | tablet; tablet, film coated | Generic drugs (ANDA) | October 15, 2020 |
| Strategic Sourcing Services LLC | 4 | tablet, film coated, extended release; tablet, sugar coated | Generic drugs (ANDA) | November 15, 2017 |
| Viatris Specialty LLC | 4 | injection | New drug applications (NDA) | December 15, 2016 |
| Xiromed, LLC | 4 | tablet; injection | Generic drugs (ANDA) | April 21, 2022 |
| Advagen Pharma Ltd | 3 | tablet | Generic drugs (ANDA) | August 19, 2019 |
| Allergan, Inc. | 3 | solution/ drops | New drug applications (NDA) | November 14, 2007 |
| American Health Packaging | 3 | tablet | Generic drugs (ANDA) | June 6, 2019 |
| Aurobindo Pharma Limited | 3 | tablet | Generic drugs (ANDA) | August 10, 2020 |
| AvKARE | 3 | tablet | Generic drugs (ANDA) | May 5, 2017 |
| AvPAK | 3 | tablet | Generic drugs (ANDA) | August 26, 2019 |
| Bausch & Lomb Incorporated | 3 | solution/ drops | New drug applications (NDA) | January 1, 2025 |
| Baxter Healthcare Corporation | 3 | injection, solution | New drug applications (NDA) | October 19, 2026 |
| Bayer HealthCare LLC. | 3 | tablet, extended release | New drug applications (NDA) | December 12, 2022 |
| First Nation Group, LLC | 3 | tablet | Generic drugs (ANDA) | August 13, 2025 |
| Fresenius Kabi USA, LLC | 3 | injection | Generic drugs (ANDA) | July 7, 2025 |
| Golden State Medical Supply, Inc. | 3 | tablet | Generic drugs (ANDA) | October 1, 2020 |
| Heritage Pharmaceuticals Inc. D/B/A Avet Pharmaceuticals Inc. | 3 | tablet | Generic drugs (ANDA) | March 25, 2026 |
| Kaleo, Inc | 3 | injection, solution | New drug applications (NDA) | November 17, 2017 |
| Meijer, Inc. | 3 | tablet, multilayer, extended release; tablet, extended release | Generic drugs (ANDA) | January 7, 2025 |
| Mylan Pharmaceuticals Inc. | 3 | tablet | Generic drugs (ANDA) | September 11, 2003 |
| NCS HealthCare of Ky, LLC DBA Vangard Labs | 3 | tablet | Generic drugs (ANDA) | August 10, 2020 |
| NDC, Inc. | 3 | injection, solution | Authorized generics (NDA) | December 4, 2015 |
| Nexus Pharmaceuticals LLC | 3 | injection | New drug applications (NDA) | March 1, 2023 |
| Novugen Pharma (USA) LLC | 3 | tablet | Generic drugs (ANDA) | October 18, 2023 |
| PD-Rx Pharmaceuticals, Inc. | 3 | tablet | Generic drugs (ANDA) | August 19, 2019 |
| Par Health USA, LLC | 3 | tablet | Generic drugs (ANDA) | October 29, 2018 |
| Rising Pharma Holdings, Inc. | 3 | tablet | Generic drugs (ANDA) | April 1, 2019 |
| Safco Dental Supply Co. | 3 | injection; injection, solution | Authorized generics (NDA) | June 1, 2016 |
| Sandoz Inc | 3 | solution/ drops; injection | Generic drugs (ANDA) | March 4, 2024 |
Dosage forms
| Dosage form | Products | Share |
|---|---|---|
| Tablet | 134 | 14.5% |
| Injection, solution | 132 | 14.3% |
| Injection | 120 | 13% |
| Tablet, film coated, extended release | 109 | 11.8% |
| Liquid | 107 | 11.6% |
| Tablet, extended release | 81 | 8.7% |
| Solution/ drops | 56 | 6% |
| Tablet, film coated | 50 | 5.4% |
| Spray | 26 | 2.8% |
| Tablet, multilayer, extended release | 21 | 2.3% |
| Syrup | 20 | 2.2% |
| Solution | 18 | 1.9% |
Updated November 6, 2026. Read from US Food and Drug Administration, National Drug Code Directory (openFDA). CC0 1.0 public domain dedication (openFDA). Counts are products in the FDA National Drug Code Directory on November 6, 2026: 138,262 products in commercial distribution, meaning without a marketing end date in the past. A company is a labeler code; one company can hold several codes, and the directory carries no address. Inclusion in the directory is not FDA approval, and the marketing category says under which kind of application or rule a product is sold. This page uses openFDA data and is not endorsed or certified by FDA. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.