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Data / Drug companies / alpha-1 Adrenergic Agonist

alpha-1 Adrenergic Agonist drugs: 174 drugs from 245 companies in the FDA NDC directory

alpha-1 Adrenergic Agonist is an FDA established pharmacologic class. The FDA National Drug Code Directory lists 1,584 products in this class from 245 companies, covering 174 drugs by generic name. The main marketing category is over the counter monograph drugs, and the newest product started marketing on October 6, 2026.

SpecStream is the live web data engine for teams and agents. It reads the National Drug Code Directory that FDA publishes, and this page is that reading. Ask for the companies that make a drug, a class or a dosage form, with their headquarters, website and size added from the web, and new listings and discontinued products arrive in your sheet, CRM, Slack or agent as FDA posts them.

  • 245Companies
  • 1,584Products
  • 174Drugs by generic name

Drugs in the alpha-1 Adrenergic Agonist class

Ranked by number of companies that list the drug.

DrugProducts hereCompanies listing it
Lidocaine1216
Acetaminophen1214
Phenylephrine hydrochloride16977
Acetaminophen, dextromethorphan hbr, phenylephrine hcl7945
Mineral oil134
Dextromethorphan hbr, guaifenesin, phenylephrine hcl4328
Mineral oil, petrolatum, phenylephrine hcl3028
Acetaminophen, guaifenesin, and phenylephrine hydrochloride5422
Cocoa butter, phenylephrine hcl2121
Phenylephrine hcl2320
Acetaminophen, guaifenesin, phenylephrine hcl2917
Aspirin, chlorpheniramine maleate, phenylephrine bitartrate2416
Acetaminophen, phenylephrine hcl2015
Acetaminophen and phenylephrine hydrochloride2213
Glycerin, phenylephrine hcl, pramoxine hcl, white petrolatum1313
Acetaminophen, chlorpheniramine maleate, phenylephrine hcl118
Acetaminophen, diphenhydramine hcl, phenylephrine hcl137
Lidocaine, phenylephrine hydrochloride97
Brompheniramine maleate, phenylephrine hcl87
Chlorpheniramine maleate, phenylephrine hcl77
Guaifenesin/phenylephrine77
Acetaminophen, phenylephrine hydrochloride116
Acetaminohpen, dextromethorphan hbr, phenylephrine hcl76
Diphenhydramine hcl, phenylephrine hcl46
Mineral oil, petrolatum, phenylephrine hci85
Acetaminophen dextromethorphan hbr phenylephrine hcl75
Acetaminophen and phenylephrine hcl65
Acetaminophen, diphenhydramine, phenylephrine55
Glycerin, lidocaine, petrolatum, phenylephrine hcl55
Guaifenesin, phenylephrine hcl54
5% lidocaine14
Acetaminophen, dextromethorphan, phenylephrine43
Dextromethorphan hbr guaifenesin phenylephrine hcl43
Lidocaine, phenylephrine hcl43
Phenylephrine hcl, witch hazel43
Acetaminophen, guaifenesin, phenylephrine hydrochloride33
Mineral oil, petrolatum, phenylephrine hydrochloride33
Glycerin, petrolatum, phenylephrine hcl, pramoxine hcl23
Pain relief13
Glycerol, phenylephine, pramoxine, petrolatum42
Cocoa butter, phenylephrine hydrochloride32
Phenylephrine hcl and chlorpheniramine maleate32
Acetaminophen, dextromethorphan hbr, phenylephrine hcl ,22
Acetaminophen, diphenhydramine hci, phenylephrine hci22
Acetaminophen, diphenhydramine hcl and phenylephrine hcl22
Acetaminophen, guaifenesin and phenylephrine hcl22
Aspirin, chlorpheniramine maleate, phylephrine bitartrate22
Childrens stuffy nose and cold22
Chlorpheniramine maleate and phenylephrine hcl22
Dextromethorphan hbr, guaifenesin, and phenylephrine hcl22
Dextromethorphan hbr, guaifenesin, phenylephrine22
Dextromethorphan hbr, guaifenesin, phenylephrine hci22
Dextromethorphan hbr, phenylephrine hcl22
Giltuss d22
Guaifenesin and phenylephrine hcl22
Hemorrhoidal22
Hemorrhoidal suppositories22
Ibuprofen, phenylephrine hydrochloride22
Lidocaine 5%, phenylephrine hydrochloride 0.25%22
Lidocaine, phenylephrine22
Phenylephrine and ketorolac22
Phenylephrine hci22
Phenylephrine, witch hazel22
Acetaminophen, guaifenesin, phenylephrine41
Lidocaine 4% phenylephrine hcl 0.25% hemorrhoid41
Hemorrhoidal rectal suppositories31
Acetaminophen and phenylephrine21
Acetaminophen and phenyleprine hcl21
Acetaminophen-phenylephrine hcl-guaifenesin21
Dextromethorphan, guaifenesin, and phenylephrine21
Guaifenesin, phenylephrine hcl,dextromethorphan hydrobromide21
Hemorrhoidal cream21
Lidocaine 4% phenylephrine hcl 0.25% hemorrhoid master21
Acetaminophen , diphenhydramine hcl,phenylephrine hcl11
Acetaminophen guaifenesein phenylephrine hcl11
Acetaminophen phenylephrine hcl chlorpheniramine maleate11
Acetaminophen, chlorpherinamine maleate, phenylephrine hci11
Acetaminophen, dextromethorphan hbr and phenylephrine hcl11
Acetaminophen, dextromethorphan hbr, phenylephrine hci11
Acetaminophen, dextromethorphan, phenylephrine hcl11
Acetaminophen, dextromethrophan hbr, phenylephrine hcl11
Acetaminophen, diphenhydramine hcl phenylephrine hcl11
Acetaminophen, diphenhydramine hcl, phenylephrine hci11
Acetaminophen, guaifenesin, phenylephrine hydrocloride11
Acetaminophen, phenylephrine hcl, guaifenesin11
Acetaminophen, phenylephrine, chlorpheniramine11
Acetaminophen, phenylephrine, dextromethorphan11
Acetaminophine dextromethorphan hbr phenylphrine hcl11
Acetaminphen11
Acteaminophen, guaifenesin, phenylephrine hcl11
Alka-seltzer plus severe cough mucus and congestion11
Brompheniramine maleate and phenylephrine hcl11
Brompheniramine maleate and phenylephrine hydrochloride11
Brompheniramine maleate, dextromethorphan, phenylephrine hcl11
Calamine, petrolatum and phenylephrine hydrochloride11
Childrens giltuss d11
Chlorpheniramine maleate and phenylephrine hydrochloride11
Chlorpheniramine maleate, ibuprofen, phenylephrine hcl11
Chlorpheniramine maleate, phenylephrine11
Chlorpheniramine maleate, phenylephrine hydrochloride11

Companies with the most products in this class

CompanyProductsMain dosage formsMain marketing categoryNewest product started
Walgreen Company78liquid; solutionOver the counter monograph drugsMarch 24, 2026
Bayer HealthCare LLC.42tablet, effervescent; capsule, liquid filledOver the counter monograph drugsJune 1, 2026
Dolgencorp, Inc. (dollar General & Rexall)36liquid; tablet, film coatedOver the counter monograph drugsJune 30, 2023
Lil' Drug Store Products, Inc.36tablet, film coated; tablet, coatedOver the counter monograph drugsJuly 3, 2025
Reckitt Benckiser LLC32solution; tablet, film coatedOver the counter monograph drugsJune 1, 2020
CVS Woonsocket Prescription Center, Incorporated31solution; liquidOver the counter monograph drugsJuly 14, 2026
Chain Drug Marketing Association, Inc.30tablet, coated; liquidOver the counter monograph drugsJune 5, 2026
Topco Associates LLC30tablet, coated; solutionOver the counter monograph drugsDecember 8, 2022
Wal-Mart Stores Inc28liquid; tablet, film coatedOver the counter monograph drugsJuly 16, 2020
CVS Pharmacy26solution; liquidOver the counter monograph drugsMarch 11, 2022
H E B26tablet, coated; capsule, liquid filledOver the counter monograph drugsApril 30, 2023
Safeway26liquid; solutionOver the counter monograph drugsSeptember 30, 2026
Amazon.com Services LLC23solution; sprayOver the counter monograph drugsOctober 2, 2026
Opmx LLC22syrup; capsule, liquid filledOver the counter monograph drugsJune 25, 2026
Rite Aid Corporation22tablet, film coated; solutionOver the counter monograph drugsJuly 9, 2024
United Natural Foods, Inc. DBA Unfi22tablet, film coated; liquidOver the counter monograph drugsJanuary 27, 2023
Cardinal Health 110, LLC. DBA Leader21tablet, film coated; solutionOver the counter monograph drugsDecember 1, 2025
Kroger Company21tablet, film coated; liquidOver the counter monograph drugsJune 1, 2026
HyVee Inc20tablet, coated; solutionOver the counter monograph drugsAugust 20, 2026
Valu Merchandisers Company20tablet, coated; liquidOver the counter monograph drugsJanuary 1, 2025
Chain Drug Marketing Association19tablet, coated; liquidOver the counter monograph drugsAugust 3, 2022
Kenvue Brands LLC19tablet, film coated; solutionOver the counter monograph drugsJune 17, 2019
WinCo Foods, LLC19liquid; tablet, film coatedOver the counter monograph drugsJune 22, 2026
Discount Drug Mart18tablet, coated; liquidOver the counter monograph drugsAugust 3, 2022
Gil Pharmaceutical Corp18tablet; solutionOver the counter monograph drugsOctober 1, 2026
Haleon US Holdings LLC18powder, for solution; syrupOver the counter monograph drugsMay 1, 2023
Kramer Novis18syrup; solutionOver the counter monograph drugsOctober 6, 2026
Family Dollar (family Wellness)17capsule, liquid filled; liquidOver the counter monograph drugsNovember 26, 2024
Pharmadel LLC17liquid; tablet, effervescentOver the counter monograph drugsJuly 1, 2026
The Procter & Gamble Manufacturing Company17liquid; solutionOver the counter monograph drugsJuly 6, 2023
Unifirst First Aid Corporation17tablet, film coated; tabletOver the counter monograph drugsSeptember 26, 2022
Shield Pharmaceuticals Corp15capsule, liquid filled; tablet, coatedOver the counter monograph drugsSeptember 11, 2026
Target Corporation15liquid; capsule, liquid filledOver the counter monograph drugsApril 1, 2025
Haleon US Holdings LLC14suppository; tablet, coatedOver the counter monograph drugsApril 30, 2025
Meijer, Inc.14tablet, film coated; capsule, liquid filledOver the counter monograph drugsJuly 31, 2025
Genomma Lab USA13syrup; liquidOver the counter monograph drugsJuly 7, 2025
L. Perrigo Company13solution; suppositoryOver the counter monograph drugsJuly 5, 2023
Meijer Distribution Inc13solution; tablet, effervescentOver the counter monograph drugsJune 6, 2024
Strategic Sourcing Services LLC13solution; tablet, film coatedOver the counter monograph drugsJune 11, 2025
Topco Associates LLC13capsule, liquid filled; solutionOver the counter monograph drugsDecember 11, 2025
Walmart Inc.13solution; capsule, liquid filledOver the counter monograph drugsSeptember 10, 2025
Amerisource Bergen12tablet, coated; tabletOver the counter monograph drugsOctober 15, 2024
CVS Pharmacy12tablet, film coated; solutionOver the counter monograph drugsJuly 20, 2015
Kroger Company12liquid; capsule, liquid filledOver the counter monograph drugsApril 30, 2026
Retail Business Services, LLC12tablet, coated; capsule, liquid filledOver the counter monograph drugsJanuary 20, 2023
Army and Air Force Exchange Service11tablet, film coated; tabletOver the counter monograph drugsJanuary 1, 2025
Harris Teeter11tablet, coatedOver the counter monograph drugsAugust 5, 2022
Humanwell PuraCap Pharmaceutical (Wuhan), Ltd.11capsule, liquid filledOver the counter monograph drugsAugust 1, 2020
Perrigo Direct, Inc11tablet, coated; creamOver the counter monograph drugsMay 1, 2025
The Procter & Gamble Manufacturing Company10capsule, liquid filled; solutionOver the counter monograph drugsApril 22, 2019
American Sales Company9solution; tablet, coatedOver the counter monograph drugsNovember 30, 2016
Jiangxi Yudexi Pharmaceutical Co., LTD9cream; ointmentOver the counter monograph drugsMarch 17, 2026
Marc Glassman, Inc.9tablet, coatedOver the counter monograph drugsOctober 5, 2022
Menper Distributors, Inc.9liquid; tabletOver the counter monograph drugsNovember 1, 2024
Publix Super Markets Inc9tablet, coated; solutionOver the counter monograph drugsFebruary 3, 2025
Reckitt Benckiser LLC9capsule, liquid filled; tablet, coatedOver the counter monograph drugsMay 1, 2023
Allegiant Health8tablet; tablet, coatedOver the counter monograph drugsNovember 12, 2021
AptaPharma Inc.8liquid; capsule, liquid filledOver the counter monograph drugsJanuary 1, 2026
Dextrum Laboratories, Inc8solution; liquidOver the counter monograph drugsApril 11, 2024
Edwards Pharmaceuticals, Inc.8liquid; tablet, coatedOver the counter monograph drugsOctober 27, 2014
Fortune Pharmacal Company Limited8tabletOver the counter monograph drugsJuly 1, 2025
Trifecta Pharmaceuticals USA LLC8ointment; creamOver the counter monograph drugsApril 10, 2026
L.N.K. International, Inc.7tablet, film coated; solutionOver the counter monograph drugsFebruary 16, 2022
Laboratorio Magnachem International SRL7syrup; tablet, coatedOver the counter monograph drugsApril 21, 2025
Lifestar Pharma LLC7solution/ drops; injectionGeneric drugs (ANDA)August 26, 2025
Medical Purchasing Solutions, LLC7injectionGeneric drugs (ANDA)March 28, 2023
Neilmed Pharmaceuticals Inc.7suppository; creamOver the counter monograph drugsFebruary 4, 2026
Poly Pharmaceuticals, Inc.7tablet; syrupOver the counter monograph drugsJune 8, 2023
Raritan Pharmaceuticals Inc7powder, for solution; liquidOver the counter monograph drugsJune 1, 2026
Somerset Therapeutics, LLC7injection; solutionGeneric drugs (ANDA)March 4, 2025
Sportpharm LLC7tablet, film coated; ointmentOver the counter monograph drugsMarch 10, 2026
Caplin Steriles Limited6injection; solution/ dropsGeneric drugs (ANDA)April 28, 2026
Gland Pharma Limited6injection; solution/ dropsGeneric drugs (ANDA)September 17, 2025
Guardian Drug Company6liquidOver the counter monograph drugsDecember 1, 2012
Hikma Pharmaceuticals USA Inc.6injection; injectable, liposomalNew drug applications (NDA)March 9, 2023
P & L Development, LLC6liquidOver the counter monograph drugsApril 30, 2021
Sandoz Inc6injectionGeneric drugs (ANDA)February 17, 2021
Softgel Healthcare Pvt Ltd6capsule, liquid filledOver the counter monograph drugsJune 19, 2025
Cabinet Health P.B.C.5tablet; capsule, liquid filledOver the counter monograph drugsOctober 5, 2026
Chain Drug Consortium, LLC5ointment; suppositoryOver the counter monograph drugsAugust 16, 2019
Demoulas Super Markets, Inc5liquid; solutionOver the counter monograph drugsJanuary 1, 2026
JHK Inc DBA American Safety & First Aid5tablet; capsule, coatedOver the counter monograph drugsJune 26, 2024
Llorens Pharmaceutical International Division, Inc.5liquid; solution/ dropsOver the counter monograph drugsAugust 1, 2019
Navajo Manufacturing Company Inc.5tablet, coated; tablet, effervescentOver the counter monograph drugsMarch 24, 2025
Target Corporation5suspension; liquidOver the counter monograph drugsAugust 3, 2026
Actipharma, LLC4solution; liquidOver the counter monograph drugsFebruary 12, 2026
BF Ascher and Co Inc4sprayOver the counter monograph drugsJune 1, 2026
Derma Care Research Labs, LLC4cream; ointmentOver the counter monograph drugsMay 12, 2023
Grocery Outlet, Inc.4liquid; capsuleOver the counter monograph drugsMarch 25, 2026
Haleon US Holdings LLC4liquid; solutionOver the counter monograph drugsJuly 1, 2015
Major Pharmaceuticals4solution; liquidOver the counter monograph drugsJuly 31, 2019
Pioneer Life Sciences, LLC4tablet; capsule, liquid filledOver the counter monograph drugsFebruary 16, 2026
Rugby Laboratories4tablet; ointmentOver the counter monograph drugsSeptember 9, 2020
Salado Sales, Inc.4tablet, film coated; liquidOver the counter monograph drugsDecember 23, 2025
Sato Pharmaceutical Co., Ltd.4tablet; capsuleOver the counter monograph drugsNovember 24, 2004
Selder, S.A. de C.V.4tablet; capsule, liquid filledOver the counter monograph drugsJune 27, 2022
A-S Medication Solutions3tablet, film coated; tabletOver the counter monograph drugsApril 5, 2023
Aaa Pharmaceutical, Inc.3tablet, coatedOver the counter monograph drugsAugust 1, 2020
Acme United Corporation3tablet, film coatedOver the counter monograph drugsJanuary 19, 2023
Advanced Generic Corporation3liquidOver the counter monograph drugsDecember 1, 2024

Dosage forms

Dosage formProductsShare
Liquid22614.3%
Solution20112.7%
Tablet, film coated19812.5%
Tablet, coated17811.2%
Capsule, liquid filled17511%
Tablet1076.8%
Injection825.2%
Cream664.2%
Ointment623.9%
Tablet, effervescent523.3%
Syrup483%
Spray392.5%

Updated November 6, 2026. Read from US Food and Drug Administration, National Drug Code Directory (openFDA). CC0 1.0 public domain dedication (openFDA). Counts are products in the FDA National Drug Code Directory on November 6, 2026: 138,262 products in commercial distribution, meaning without a marketing end date in the past. A company is a labeler code; one company can hold several codes, and the directory carries no address. Inclusion in the directory is not FDA approval, and the marketing category says under which kind of application or rule a product is sold. This page uses openFDA data and is not endorsed or certified by FDA. Free to reuse with credit to SpecStream under CC BY 4.0. Spot a wrong value? Write to [email protected] with the link to this page.