# New Early phase 1 clinical trials: 1,227

Updated November 9, 2026.

1,227 clinical studies in early phase 1 were first posted on ClinicalTrials.gov from November 12, 2024 to November 9, 2026; 182 have an industry sponsor and 924 are recruiting or about to. The newest, NCT07925411, was posted on November 9, 2026: Bilateral PENG Block for Total Vaginal Hysterectomy (University of Illinois Chicago).

## The full list

New Early phase 1 clinical trials: 1,227 rows for $61.35, first posted on ClinicalTrials.gov from November 12, 2024 to November 9, 2026. Columns: NCT ID, Title, Sponsor, Sponsor class, Phase, Status, Conditions, Condition groups (MeSH), Interventions, Start date, First posted, Enrollment, Enrollment type, Location countries, Central contact, Contact phone, Contact email, Last update posted, Read on, Source. The new rows each week by email, about 39 rows a month: $19 a month. Pay by card with no account. Prices exclude VAT. CSV and Excel files with the columns this page does not show (central contact, contact phone, contact email, sponsor class, condition groups (MeSH), interventions and 5 more), which open on your screen as soon as the payment clears and come by email. The rows on this page are a sample.

Buy: https://specstream.ai/data/clinical-trials/phase/early-phase-1

SpecStream is the live web data engine for teams and agents. It reads every new study on ClinicalTrials.gov each morning, and this page is that reading. Ask for the conditions, phases or countries you follow and each new trial arrives in your sheet, CRM, Slack or agent with the sponsor, the sites and the listed contact.

- New trials: 1,227
- Industry sponsored: 182
- Recruiting or not yet: 924
- Latest posted: November 9, 2026

## Newest trials

The newest 100 of 1,227, each linked to its record. The full list holds every one with the sponsor class, interventions, start date and the central contact as the record prints it.

| First posted | NCT ID | Title | Sponsor | Phase | Status | Conditions | Enrollment | Countries | Source |
| --- | --- | --- | --- | --- | --- | --- | --- | --- | --- |
| November 9, 2026 | NCT07925411 | Bilateral PENG Block for Total Vaginal Hysterectomy | University of Illinois Chicago | Early phase 1 | Not yet recruiting | Pericapsular Nerve Group Block (PENG Block), Total Vaginal Hysterectomy | 30 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07925411) |
| November 6, 2026 | NCT07923786 | Clinical Study of 68Ga-labeled Novel EPHA2 Cyclic Peptides PET/CT for Imaging of Solid Tumors | The First Affiliated Hospital of Soochow University | Early phase 1 | Active not recruiting | Solid Tumor Malignancies | 12 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07923786) |
| November 5, 2026 | NCT07917923 | A Clinical Study to Evaluate the Safety and Efficacy of GT802 Injection in the Treatment of Refractory Generalized Myasthenia Gravis | Daishi Tian | Early phase 1 | Not yet recruiting | Generalized Myasthenia Gravis (gMG) | 12 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07917923) |
| November 3, 2026 | NCT07911670 | Exploratory Clinical Trial of UX-DA003 Injection for the Treatment of Patients With Parkinson's Disease | The First Affiliated Hospital of Anhui Medical University | Early phase 1 | Recruiting | PARKINSON DISEASE (Disorder) | 12 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07911670) |
| November 2, 2026 | NCT07910838 | Single-dose Effects of Ayahuasca Compared to Esketamine on Experimentally Induced Pain | University of Sao Paulo | Early phase 1 | Completed | Healthy Adult Participants | 20 | Brazil | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07910838) |
| November 2, 2026 | NCT07910097 | Flurpiridaz F-18 PET/CT Imaging for Detecting Parathyroid Adenomas | University of Pennsylvania | Early phase 1 | Recruiting | Hyperparathyroidism | 20 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07910097) |
| November 2, 2026 | NCT07908329 | Intradermal Influenza Vaccination | Yale University | Early phase 1 | Recruiting | Vaccine Reaction | 139 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07908329) |
| November 2, 2026 | NCT07908251 | a Novel siRNA Eyedrops for DED Treatment | Eye & ENT Hospital of Fudan University | Early phase 1 | Not yet recruiting | Dry Eye | 30 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07908251) |
| October 30, 2026 | NCT07908147 | Biomarker-guided RAdiation-deferring Treatment in Younger GBM Patients - Pilot Study | Olivia Newton-John Cancer Research Institute | Early phase 1 | Not yet recruiting | IDH Wildtype Glioblastoma, Glioblastoma (GBM) | 12 | Australia | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07908147) |
| October 30, 2026 | NCT07906652 | Clinical Evaluation of the Safety and Efficacy of "Buyan Huan Wu Tang" Combined With Atorvastatin in the Treatment of Atypical Pneumonia | The First Affiliated Hospital with Nanjing Medical University | Early phase 1 | Enrolling by invitation | Moyamoya Disease | 300 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07906652) |
| October 29, 2026 | NCT07905144 | A Clinical Study Evaluating the Safety and Preliminary Effectiveness of Induced Pluripotent Stem Cell-derived Platelets in Patients With... | Ruijin Hospital | Early phase 1 | Not yet recruiting | Thrombocytopenia | 9 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07905144) |
| October 29, 2026 | NCT07903961 | Phosphate & Kidney Stones | University of Chicago | Early phase 1 | Not yet recruiting | Kidney Stones, Calcium Oxalate Kidney Stones, Hypophosphatemia | 5 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07903961) |
| October 29, 2026 | NCT07903870 | Efficacy of the pA1c®HI Postbiotic in Metabolic Regulation in Healthy Individuals With Hyperglycemia | Genbioma Aplicaciones SL | Early phase 1 | Not yet recruiting | Hyperglycemias, Prediabetes | 100 | Spain | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07903870) |
| October 29, 2026 | NCT07903376 | SPX-01 Gene Therapy in Pediatric Patients With Spinal Muscular Atrophy Type 1 (RISE) | Exir Gene Pharmed | Early phase 1 | Not yet recruiting | Spinal Muscular Atrophy (SMA) | 1 | Iran | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07903376) |
| October 28, 2026 | NCT07902141 | A Web-based Intervention Program for Postpartum Depression | Babes-Bolyai University | Early phase 1 | Recruiting | Postpartum Depression (PPD), Web-based Intervention | 30 | Romania | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07902141) |
| October 27, 2026 | NCT07897292 | The Efficacy of Exosomes Combined With Synthetic Bone Graft for the Treatment of Periodontal Intra-bony Defects | Khoshoe Al-mokhtar Mohammed | Early phase 1 | Not yet recruiting | Intra-Bony Defects in Periodontitis Patients | 30 | Egypt | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07897292) |
| October 27, 2026 | NCT07896902 | Xenon MRI to Evaluate Changes to Lung Function Following Bronchoscopic Treatment of Air Trapping in Emphysema | Apreo Health, Inc. | Early phase 1 | Recruiting | Air Trapping, Emphysema, Hyperinflation | 15 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07896902) |
| October 26, 2026 | NCT07894640 | Clinical Safety and Efficacy Evaluation of the Blood-cooling and Stasis-removing Formula as an Adjunct to Atorvastatin in the Treatment of... | The First Affiliated Hospital with Nanjing Medical University | Early phase 1 | Enrolling by invitation | Moyamoya Disease | 60 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07894640) |
| October 26, 2026 | NCT07894289 | Examining the Role of Sensitivity to Uncertain Threat and Alcohol Response in Risk for Alcohol Use Disorder Following Sexual Assault in... | Ohio State University | Early phase 1 | Not yet recruiting | Sexual Assault, Alcohol Intoxication | 220 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07894289) |
| October 26, 2026 | NCT07894276 | Pain Sensitivity, Alcohol-Induced Analgesia, and Heavy Drinking in Individuals With Opioid Use Disorder | Ohio State University | Early phase 1 | Not yet recruiting | Opioid Use Disorder, Alcohol Intoxication, Pain | 90 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07894276) |
| October 26, 2026 | NCT07893912 | Acute Effects of a Single Dose of Ayahuasca on Cerebral Metabolism in Healthy Volunteers: a PET Study | University of Sao Paulo | Early phase 1 | Enrolling by invitation | Healthy Adult Participants | 15 | Brazil | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07893912) |
| October 26, 2026 | NCT07893769 | Effects of Different Doses of Ayahuasca on Personality in Healthy Volunteers | University of Sao Paulo | Early phase 1 | Completed | Healthy Adult Participants | 28 | Brazil | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07893769) |
| October 23, 2026 | NCT07892300 | Implantable Microdevices for in Situ Evaluation of Drug Responses in Lung Cancer | Oliver Jonas | Early phase 1 | Not yet recruiting | Lung Cancer, Mesothelioma, Suspected Lung Cancer, Suspected Mesothelioma | 20 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07892300) |
| October 23, 2026 | NCT07891364 | GBP-213 in Patients With Autosomal Dominant Polycystic Kidney Disease | RenJi Hospital | Early phase 1 | Not yet recruiting | Autosomal Dominant Polycystic Kidney | 24 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07891364) |
| October 22, 2026 | NCT07888595 | Systemic and Topical Geroprotective Rejuvenation Assessed by START/REST Aging Clocks | Frontiers in Bioscience Research Institute and Aging | Early phase 1 | Enrolling by invitation | Aging | 48 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07888595) |
| October 21, 2026 | NCT07886606 | Cannabidiol in Opioid Use Disorder and Chronic Pain With Buprenorphine | Yale University | Early phase 1 | Recruiting | Chronic Pain, Opioid Use Disorder | 34 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07886606) |
| October 21, 2026 | NCT07886567 | reALIGNing Circadian Rhythm and Promoting Sleep in the Intensive Care Unit | University of Alberta | Early phase 1 | Not yet recruiting | Sleep, Circadian Dysregulation, ICU, Delirium in Intensive Care Unit | 50 | Canada | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07886567) |
| October 21, 2026 | NCT07886320 | Adapalene Gel for Acute Radiation-Induced Skin Injury | Yunnan Cancer Hospital | Early phase 1 | Recruiting | Radiation Dermatitis | 50 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07886320) |
| October 21, 2026 | NCT07886138 | RET-Targeted Molecular Imaging Probes in Prostate Cancer | Xiangya Hospital of Central South University | Early phase 1 | Active not recruiting | Prostate Adenocarcinoma With Focal Neuroendocrine Differentiation, Prostate Cancer | 50 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07886138) |
| October 21, 2026 | NCT07885813 | NRI: Robot-Assisted Longitudinal Physical and Cognitive Exercise Interventions for Older Veterans | Oregon State University | Early phase 1 | Active not recruiting | Active Control (Robot on Screen), Adaptive Assistive Robot | 12 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07885813) |
| October 20, 2026 | NCT07884448 | PliaFX Flo Subtalar Fusion Study | St. Paul's Hospital, Canada | Early phase 1 | Not yet recruiting | Subtalar Arthrodesis | 50 | Canada | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07884448) |
| October 20, 2026 | NCT07884344 | Window of Opportunity Study of Lixumistat in Patients With Newly Diagnosed Glioblastoma | Macarena De La Fuente, MD | Early phase 1 | Recruiting | Glioblastoma | 10 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07884344) |
| October 20, 2026 | NCT07883642 | Traditional Chinese Medicine Treatment for Capecitabine-Related Hand-Foot Syndrome | Emeishan Hospital of Traditional Chinese Medicine | Early phase 1 | Not yet recruiting | Palmar and Plantar Erythema, Numbness of the Four Limbs, Pain in the Distal Extremities, Peeling of the Soles and Palms | 7 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07883642) |
| October 20, 2026 | NCT07883317 | A First-in-Human Study to Evaluate the Safety and Efficacy of Left Ventricular Assist Device Combined With Exosome Therapy for Patients... | Yining Yang | Early phase 1 | Not yet recruiting | Heart Failure | 24 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07883317) |
| October 19, 2026 | NCT07879547 | Safety and Diagnostic Efficacy of 177Lu-AF03 in Patients With Solid Tumors | Yong He | Early phase 1 | Not yet recruiting | Malignant Solid Tumors, Neoplasms | 8 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07879547) |
| October 16, 2026 | NCT07878572 | Extension Study of the PUMCH-E101 Clinical Trial：Safety and Efficacy Study of PUMCH-E101 Injection in the Contralateral Eye | Peking Union Medical College Hospital | Early phase 1 | Enrolling by invitation | Inherited Retinal Diseases | 8 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07878572) |
| October 16, 2026 | NCT07878026 | Oral Aeromonas sp. MTB Phage Therapy for Pouchitis in Patients With Ulcerative Colitis (UC) | Jinling Hospital, China | Early phase 1 | Not yet recruiting | Pouchitis, UC - Ulcerative Colitis | 12 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07878026) |
| October 15, 2026 | NCT07875946 | 68Ga- and 18F-CAIX PET Imaging Study | Peking University First Hospital | Early phase 1 | Not yet recruiting | Renal Cell Carcinoma, Clear Cell Renal Cell Carcinoma, Renal Tumor | 100 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07875946) |
| October 15, 2026 | NCT07875868 | Radial Extracorporeal Shock Wave Therapy as an Adjunct to Botulinum Toxin Type A for Post-Stroke Lower Limb Spasticity (SOLUTION) | Parc de Salut Mar | Early phase 1 | Completed | Stroke, Spasticity as Sequela of Stroke, Lower Limb Spasticity, Upper Motor Neuron Syndrome | 20 | Spain | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07875868) |
| October 15, 2026 | NCT07875322 | Silymarin Versus N-Acetylcysteine as Protective Effect Against Anti-tuberculosis Drugs Induced Liver Injury. | Assiut University | Early phase 1 | Not yet recruiting | Drug-Induced Acute Liver Injury, Tuberculosis (TB) | 102 | Egypt | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07875322) |
| October 15, 2026 | NCT07874945 | Peripheral Vascular Effects of Insulin in Obesity | University of Missouri-Columbia | Early phase 1 | Not yet recruiting | Obesity (BMI\>30), Insulin Resistance | 64 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07874945) |
| October 14, 2026 | NCT07873970 | 25BT056: Basket Study of Viral Cytotoxic T Lymphocytes | Children's Hospital of Philadelphia | Early phase 1 | Not yet recruiting | EBV Viremia, CMV Viremia, BK Viremia, Adenovirus, Post-transplant Lymphoproliferative Disorder, Viremia... | 35 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07873970) |
| October 14, 2026 | NCT07873671 | A Trial of RLX-2508-102 in Healthy Volunteers | Atridia Pty Ltd. | Early phase 1 | Not yet recruiting | Influenza | 101 | Australia | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07873671) |
| October 13, 2026 | NCT07871643 | Cardiocentric Inotropic Optimization in Spinal Cord Injury | University of British Columbia | Early phase 1 | Not yet recruiting | SCI - Spinal Cord Injury | 8 | Canada | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07871643) |
| October 13, 2026 | NCT07869823 | Cemiplimab and Quad Shot Radiation for Cutaneous Squamous Cell Carcinoma in the Head and Neck | Vanderbilt-Ingram Cancer Center | Early phase 1 | Recruiting | Cutaneous Squamous Cell Carcinoma | 25 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07869823) |
| October 8, 2026 | NCT07866508 | Comparison of Analgesic Efficacy of Intrathecal Bupivacaine Versus Bupivacaine Plus Dexmedetomidine in Patients Undergoing Orthopedic... | Sheikh Khalifa Bin Zayed Al Nahyan Combined Military Hospital Muzaffarabad | Early phase 1 | Active not recruiting | Postoperative Pain, Pain, Orthopaedic Surgery, Anesthesia, Spinal | 80 | Pakistan | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07866508) |
| October 8, 2026 | NCT07865871 | Role of Inhaled Polymyxin as an Adjunct to Intravenous Therapy in Multidrug Resistant Ventilator-associated Pneumonia in Stroke Patients | Ain Shams University | Early phase 1 | Not yet recruiting | Ventilator Associated Pneumonia ( VAP) | 78 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07865871) |
| October 8, 2026 | NCT07865832 | A Study of CA9-Targeted CAR Macrophage Therapy in Advanced Clear Cell Renal Cell Carcinoma | Liangyou Gu | Early phase 1 | Not yet recruiting | Clear Cell Renal Cell Carcinoma | 6 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07865832) |
| October 7, 2026 | NCT07862010 | Study of GI001 in Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma and B-Cell Acute Lymphoblastic Leukemia | Hematology department of the 920th hospital | Early phase 1 | Recruiting | B-Cell Non-Hodgkin Lymphoma, B-Cell Acute Lymphoblastic Leukemia | 18 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07862010) |
| October 6, 2026 | NCT07861464 | BPPV Recurrence After CRM With & Without Supplementation | University of Jordan | Early phase 1 | Completed | Benign Paroxismal Positional Vertigo | 404 | Jordan | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07861464) |
| September 29, 2026 | NCT07845825 | Aprepitant for the Treatment of CLIFAHDD | The University of Texas Health Science Center at San Antonio | Early phase 1 | Recruiting | CLIFAHDD, Congenital Contractures of the Limbs and Face, Hypotonia, and Developmental Delay, NALCN Channelopathy... | 5 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07845825) |
| September 25, 2026 | NCT07843030 | Effect and Mechanism of Jiajian Guishen Optimized Formula on Premature Ovarian Insufficiency: Insights Into m6A Modification and Oxidative... | Shi Yun | Early phase 1 | Not yet recruiting | Premature Ovarian Insufficiency | 45 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07843030) |
| September 25, 2026 | NCT07841548 | Guishen Yijing Granules for Diminished Ovarian Reserve With Kidney Deficiency Syndrome: A Randomized Controlled Trial | Shi Yun | Early phase 1 | Not yet recruiting | Diminished Ovarian Reserve (DOR) | 120 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07841548) |
| September 24, 2026 | NCT07837830 | Early Intervention With Inhaled Treprostinil Among Patients With Exercise-Induced Pulmonary Hypertension (EPIH) | Valley Health System | Early phase 1 | Recruiting | Pulmonary Hypertension | 32 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07837830) |
| September 23, 2026 | NCT07837284 | Medication vs. Meditation for Chronic Knee Osteoarthritis | Florida State University | Early phase 1 | Not yet recruiting | Knee Osteoarthristis | 30 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07837284) |
| September 23, 2026 | NCT07836725 | Radiographic Changes in the Maxillary Sinus Following Closed Sinus Augmentation With Leukocyte Platelet Rich Fibrin | The University of Texas Health Science Center at San Antonio | Early phase 1 | Not yet recruiting | Partially Edentulous Maxilla | 25 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07836725) |
| September 22, 2026 | NCT07835308 | Bayesian Optimization of DBS for Gait | University of Minnesota | Early phase 1 | Recruiting | Parkinson Disease (PD) | 15 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07835308) |
| September 22, 2026 | NCT07833384 | The Effect of Providing Genetic Risk Information on Lifestyle Behaviors in African Americans | Pennington Biomedical Research Center | Early phase 1 | Completed | Diabetes, Hypercholesterolaemia, Hypertension, Obesity Type 2 Diabetes Mellitus, Obesity & Overweight, Heart Failure... | 60 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07833384) |
| September 22, 2026 | NCT07832578 | Comparison of Aspirin Alone Versus Low-Dose Rivaroxaban Plus Aspirin in Chronic Limb-Threatening Ischemia | King Edward Medical University | Early phase 1 | Recruiting | Limb Ischemia | 78 | Pakistan | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07832578) |
| September 21, 2026 | NCT07830771 | Fibroblast Activating Protein (FAP) PET/CT in Adults With Tuberculosis | University of Pennsylvania | Early phase 1 | Recruiting | Tuberculosis, Pulmonary | 10 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07830771) |
| September 21, 2026 | NCT07830238 | SNC116 Therapy for Relapsed/Refractory B-cell Acute Lymphoblastic Leukemia | Shanghai Simnova Biotechnology Co.,Ltd. | Early phase 1 | Not yet recruiting | B-cell Acute Lymphoblastic Leukemia | 28 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07830238) |
| September 18, 2026 | NCT07828678 | PET/CT Imaging of GRPR Expression in Various Tumors | Jewish General Hospital | Early phase 1 | Not yet recruiting | Malignancies Multiple | 60 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07828678) |
| September 17, 2026 | NCT07826936 | Nerve Block for Severe Abdominal Pain in the Emergency Department | University of California, Irvine | Early phase 1 | Recruiting | Erector Spinae Plane Block | 30 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07826936) |
| September 17, 2026 | NCT07825818 | Imaging Mitochondrial Complex-I in Alcohol Use Disorder | Rajesh Narendran | Early phase 1 | Recruiting | Alcohol Use Disorder (AUD), Healthy Controls Group - Age and Sex-matched | 100 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07825818) |
| September 17, 2026 | NCT07825155 | Ultrasound-Guided Injection of Carpal Tunnel Syndrome Using Hyaluronic Acid vs Corticosteroid vs Glucose 5% | Tanta University | Early phase 1 | Recruiting | Carpal Tunnel Syndrome (CTS) | 60 | Egypt | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07825155) |
| September 16, 2026 | NCT07823868 | Frankincense Versus Sodium Hypochlorite for Root Canal Disinfection | Oman Dental College | Early phase 1 | Not yet recruiting | Pulp Necrosis, Root Canal Infection, Apical Periodontitis | 30 | Oman | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07823868) |
| September 16, 2026 | NCT07821866 | Comparing the Effectiveness of Hyalone and Calcium Hydroxide in Reducing Post-operative Pain and Promoting Periapical Healing. | Future University in Egypt | Early phase 1 | Active not recruiting | Pain Management | 24 | Egypt | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07821866) |
| September 16, 2026 | NCT07821697 | Translational Recording and Characterization of Epilepsy Signals Using Subgaleal EEG During Standard-of-care SEEG Monitoring | Adraxe Corp. | Early phase 1 | Not yet recruiting | Epilepsy (Treatment Refractory) | 15 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07821697) |
| September 15, 2026 | NCT07821177 | Bladder Preservation or Cystectomy for MIBC | Dana-Farber Cancer Institute | Early phase 1 | Active not recruiting | Muscle-Invasive Bladder Carcinoma, Bladder Cancer, Urothelial Carcinoma | 20 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07821177) |
| September 15, 2026 | NCT07820722 | Assessing Heart and Brain Metabolism in Type II Diabetes Mellitus Patients Using Carbon-13 MRI | Sunnybrook Health Sciences Centre | Early phase 1 | Not yet recruiting | Diabete Type 2 | 32 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07820722) |
| September 14, 2026 | NCT07817537 | Evaluating the Effectiveness of Intramuscular Versus Intravenous Tranexamic Acid for Minimizing Blood Loss After Total Hip Arthroplasty: A... | Alexandria University | Early phase 1 | Recruiting | Blood Loss After a Total Hip Replacement | 128 | Egypt | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07817537) |
| September 11, 2026 | NCT07814391 | Reconstructive Treatment of Peri-implantitis With Electrolytic Decontamination Versus Titanium Brushes | George Eastman Dental Hospital, Italy | Early phase 1 | Not yet recruiting | Peri-Implantitis and Peri-implant Mucositis | 38 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07814391) |
| September 10, 2026 | NCT07813533 | A Pilot Study to Examine the Efficacy and Tolerability of Sirolimus on Epidermal Nevi Lesions in Patients 6 Years Old and Above. | Northwestern University | Early phase 1 | Not yet recruiting | Epidermal Nevi | 14 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07813533) |
| September 10, 2026 | NCT07813091 | Controlled Oxygen Desaturation Study of the Neonatal Wireless Transmission System | Kathryn Beardsall | Early phase 1 | Not yet recruiting | Testing Accuracy, Device Performance | 24 | United Kingdom | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07813091) |
| September 10, 2026 | NCT07812636 | Tirzepatide and Levonorgestrel IUD Therapy for EIN and Early-Stage Endometrial Cancer | Milton S. Hershey Medical Center | Early phase 1 | Not yet recruiting | Grade 1 Endometrial Endometrioid Carcinoma, Endometrial Intraepithelial Neoplasia, Metabolic Comorbidities | 15 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07812636) |
| September 10, 2026 | NCT07812259 | Clinical Tolerance of an Intraparotid Injection of Bupivacaine, Combined With Dexamethasone, After Parotidectomy for Benign Tumor | Centre Hospitalier Universitaire de Nīmes | Early phase 1 | Recruiting | Parotid Neoplasm, Bupivacaine, Dexamethasone | 10 | France | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07812259) |
| September 8, 2026 | NCT07808177 | Clinical Evaluation of 177Lu-FAP-VG11 Injection in Patients With Fibroblast Activation Protein -Positive Advanced Solid Tumours | Shandong Cancer Hospital and Institute | Early phase 1 | Recruiting | Fibroblast Activation Protein (FAP)-Positive Advanced Solid Tumours | 7 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07808177) |
| September 8, 2026 | NCT07806136 | Biomarker-Guided Mycophenolate Mofetil Elimination in Low-Risk Older Adult Kidney Transplant Recipients | Virginia Commonwealth University | Early phase 1 | Not yet recruiting | Kidney Transplant Recipient | 20 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07806136) |
| September 8, 2026 | NCT07806045 | Nebulized UC-EVs for Recurrent or Refractory IMIDs With Lung Involvement | Qiubai Li | Early phase 1 | Not yet recruiting | IgG4 Related Disease, Systemic Sclerosis (SSc) | 18 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07806045) |
| September 4, 2026 | NCT07804459 | Individualized fMRI-guided TMS for Depression | University of Pennsylvania | Early phase 1 | Not yet recruiting | Depression, Major Depressive Disorder (MDD), Depression - Major Depressive Disorder, Persistent Depressive Disorder... | 60 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07804459) |
| September 4, 2026 | NCT07803978 | Prospective Randomized Controlled Study: Amimaitosai Injection Combined With Corticosteroids for Gastrointestinal aGVHD | Chinese PLA General Hospital | Early phase 1 | Enrolling by invitation | Acute Gastrointestinal Graft-versus-host Disease | 60 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07803978) |
| September 3, 2026 | NCT07802756 | Dose-Escalation/Expansion Study of iMagic in Relapsed/Refractory Hematologic Malignancies | Suzhou Immunofoco Biotechnology Co., Ltd | Early phase 1 | Not yet recruiting | Relapsed/Refractory Hematologic Malignancies | 30 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07802756) |
| September 3, 2026 | NCT07801976 | Positron Emission Tomography (PET) Imaging of Reactive Oxygen and Nitrogen Species: Human Observation of Retention and Safety of... | St. Jude Children's Research Hospital | Early phase 1 | Not yet recruiting | Healthy Volunteer | 10 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07801976) |
| September 2, 2026 | NCT07800910 | Dexmedetomidine Trial for Effects on Rhythms, Sleep Architecture, and Biomarker Dynamics in Older Adults | Massachusetts General Hospital | Early phase 1 | Not yet recruiting | Sleep, Circadian Rhythm | 12 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07800910) |
| September 2, 2026 | NCT07800481 | PET Imaging of Natriuretic Peptide Receptor C (NPR-C) in Carotid Atherosclerosis With 64Cu-NODAGA-CANF (Volunteer - Dosimetry Study) | Washington University School of Medicine | Early phase 1 | Recruiting | Healthy Adult, Healthy | 8 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07800481) |
| September 1, 2026 | NCT07798778 | Clinical Evaluation of SRT-017 in Patients With PSMA-Positive Metastatic Castration-Resistant Prostate Cancer | Affiliated Hospital of Jiangnan University | Early phase 1 | Recruiting | Metastatic Castration-Resistant Prostate Cancer | 18 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07798778) |
| September 1, 2026 | NCT07797829 | Buccal Mucosal Graft Ureteroplasty for Treatment of Proximal Ureteric Strictures, A Clinical Case Series. | Mohamed Salah Abdul Mawgoud | Early phase 1 | Not yet recruiting | Ureter Stricture | 25 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07797829) |
| August 31, 2026 | NCT07794956 | LpD3.5 Intervention Study in Older Adults- LISA-I Trial | University of South Florida | Early phase 1 | Recruiting | Mild Cognitive Impairment (MCI), Cognition, Brain Aging, Microbiome Dysbiosis, Leaky Gut Syndrome, Gut Inflammation... | 15 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07794956) |
| August 28, 2026 | NCT07793500 | YSCH-01 Via Nebulization in Pulmonary Metastasis of Advanced Solid Tumors and Non-small Cell Lung Cancer (NSCLC) | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | Early phase 1 | Recruiting | NSCLC, Advanced Solid Tumor | 36 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07793500) |
| August 27, 2026 | NCT07790939 | 89Zr-DFO-Mirvetuximab PET/CT Imaging for Companion Diagnosis and Response Evaluation in Ovarian Cancer | Peking University Cancer Hospital & Institute | Early phase 1 | Not yet recruiting | Epithelial Ovarian Cancer, Ovarian Cancer | 20 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07790939) |
| August 26, 2026 | NCT07787923 | Safety, Tolerability, and Preliminary Efficacy of Intra-Articular Injection of Mesenchymal Stem Cell-Derived Exosomes for the Treatment of... | Beijing Jishuitan Hospital | Early phase 1 | Not yet recruiting | Non Traumatic Osteonecrosis of the Femoral Head (Hip) | 15 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07787923) |
| August 25, 2026 | NCT07785908 | Individualized (fMRI-guided) TMS Intervention for Post-Traumatic Stress Disorder (PTSD) | University of Pennsylvania | Early phase 1 | Not yet recruiting | PTSD, Post Traumatic Stress Disorder (PTSD) | 60 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07785908) |
| August 25, 2026 | NCT07785102 | Single Day of Ultra-accelerated TMS With a Single Dose of NRX-101 | Mclean Hospital | Early phase 1 | Recruiting | Major Depression | 30 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07785102) |
| August 25, 2026 | NCT07784985 | A Study of NST-628 in Recurrent Grade 4 Glioma | Nader Sanai | Early phase 1 | Not yet recruiting | Glioma, Recurrent High Grade, Grade 4 Malignant Glioma | 12 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07784985) |
| August 24, 2026 | NCT07781852 | Evaluation of the Distribution of 64Cu/68Ga Labeled CM500 in Healthy Volunteers and Patients With Cancer | Lumina Pharmaceuticals Inc | Early phase 1 | Not yet recruiting | Bladder Cancer, Glioma, Glioblastoma (GBM), Breast Cancer, Colorectal Cancer, Esophageal Cancer, Gastric Cancer (GC)... | 40 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07781852) |
| August 24, 2026 | NCT07781826 | Influence of Neurohormonal Blockade on Natriuresis in Heart Failure Patients | Wroclaw Medical University | Early phase 1 | Completed | Heart Failure | 80 | Poland | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07781826) |
| August 21, 2026 | NCT07778979 | Multiparametric Metabolic and Hypoxic PET/MRI Imaging Substudy in Gliomas | University of Alabama at Birmingham | Early phase 1 | Not yet recruiting | Glioma | 20 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07778979) |
| August 21, 2026 | NCT07778602 | Safety and Feasibility of First-line Avutometinib and Defactinib in Patients With Newly Diagnosed High-grade Gliomas | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | Early phase 1 | Not yet recruiting | MGMT-unmethylated Glioblastoma (GBM), IDH Wildtype Glioblastoma | 22 | Puerto Rico, United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07778602) |
| August 21, 2026 | NCT07778472 | Topical Tripelennamine 1% Cream Versus Diphenhydramine 1% Cream for the Relief of Histamine-Induced Itching: A Proof Concept Study in... | Palm Beach Atlantic University | Early phase 1 | Completed | Healthy | 37 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07778472) |
| August 19, 2026 | NCT07774650 | A Study of the Pharmacokinetics, Biodistribution and Dosimetry of Granzyme-B Targeted \[Cu-64\]-Labeled PET Radiotracers in Adult Healthy... | Ratio Therapeutics, Inc. | Early phase 1 | Recruiting | Healthy Volunteer | 12 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07774650) |

## Sponsors posting most

| Sponsor | New trials | Latest |
| --- | --- | --- |
| Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 25 | August 6, 2026 |
| Institute of Hematology & Blood Diseases Hospital, China | 16 | July 8, 2026 |
| Zhejiang University | 15 | March 23, 2026 |
| Peking Union Medical College Hospital | 14 | October 16, 2026 |
| Ruijin Hospital | 12 | October 29, 2026 |
| Cancer Institute and Hospital, Chinese Academy of Medical Sciences | 12 | August 28, 2026 |
| Chinese PLA General Hospital | 11 | September 4, 2026 |
| The First Affiliated Hospital with Nanjing Medical University | 10 | October 30, 2026 |
| Massachusetts General Hospital | 10 | September 2, 2026 |
| Washington University School of Medicine | 9 | September 2, 2026 |
| Grit Biotechnology | 9 | June 30, 2026 |
| Cairo University | 9 | May 22, 2026 |
| Shanghai Zhongshan Hospital | 9 | April 30, 2026 |
| Shanghai Changzheng Hospital | 9 | April 13, 2026 |
| Assiut University | 8 | October 15, 2026 |
| Beijing Tiantan Hospital | 8 | June 18, 2026 |
| Mayo Clinic | 8 | March 10, 2026 |
| Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine | 8 | February 27, 2026 |
| University of Pennsylvania | 7 | November 2, 2026 |
| Northwestern University | 7 | September 10, 2026 |

## Conditions

| Condition group | New trials | Latest |
| --- | --- | --- |
| [Recurrence](https://specstream.ai/data/clinical-trials/condition/recurrence) | 30 | August 19, 2026 |
| [Neoplasms](https://specstream.ai/data/clinical-trials/condition/neoplasms) | 25 | October 19, 2026 |
| [Lupus Erythematosus, Systemic](https://specstream.ai/data/clinical-trials/condition/lupus-erythematosus-systemic) | 25 | August 5, 2026 |
| [Multiple Myeloma](https://specstream.ai/data/clinical-trials/condition/multiple-myeloma) | 25 | July 27, 2026 |
| [Autoimmune Diseases](https://specstream.ai/data/clinical-trials/condition/autoimmune-diseases) | 25 | July 13, 2026 |
| [Glioblastoma](https://specstream.ai/data/clinical-trials/condition/glioblastoma) | 19 | October 30, 2026 |
| [Scleroderma, Systemic](https://specstream.ai/data/clinical-trials/condition/scleroderma-systemic) | 19 | September 8, 2026 |
| [Obesity](https://specstream.ai/data/clinical-trials/condition/obesity) | 17 | October 15, 2026 |
| [Prostatic Neoplasms](https://specstream.ai/data/clinical-trials/condition/prostatic-neoplasms) | 15 | October 21, 2026 |
| [Colorectal Neoplasms](https://specstream.ai/data/clinical-trials/condition/colorectal-neoplasms) | 15 | August 24, 2026 |
| [Leukemia, Myeloid, Acute](https://specstream.ai/data/clinical-trials/condition/leukemia-myeloid-acute) | 15 | August 18, 2026 |
| [Parkinson Disease](https://specstream.ai/data/clinical-trials/condition/parkinson-disease) | 14 | November 3, 2026 |
| [Pancreatic Neoplasms](https://specstream.ai/data/clinical-trials/condition/pancreatic-neoplasms) | 14 | August 24, 2026 |
| [Pain](https://specstream.ai/data/clinical-trials/condition/pain) | 13 | October 26, 2026 |
| [Breast Neoplasms](https://specstream.ai/data/clinical-trials/condition/breast-neoplasms) | 13 | August 24, 2026 |
| Lymphoma, B-Cell | 12 | October 7, 2026 |
| Glomerulonephritis, IGA | 12 | August 6, 2026 |
| Myositis | 12 | May 19, 2026 |
| [Diabetes Mellitus](https://specstream.ai/data/clinical-trials/condition/diabetes-mellitus) | 11 | September 22, 2026 |
| [Inflammation](https://specstream.ai/data/clinical-trials/condition/inflammation) | 11 | August 31, 2026 |
| [Glioma](https://specstream.ai/data/clinical-trials/condition/glioma) | 11 | August 25, 2026 |
| Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis | 11 | May 19, 2026 |
| [Carcinoma, Non-Small-Cell Lung](https://specstream.ai/data/clinical-trials/condition/carcinoma-non-small-cell-lung) | 10 | October 23, 2026 |
| Burkitt Lymphoma | 10 | October 7, 2026 |
| [Overweight](https://specstream.ai/data/clinical-trials/condition/overweight) | 10 | September 22, 2026 |

## By country

| Country | New trials | Latest |
| --- | --- | --- |
| [China](https://specstream.ai/data/clinical-trials/country/china) | 433 | November 6, 2026 |
| [United States](https://specstream.ai/data/clinical-trials/country/united-states) | 342 | November 2, 2026 |
| [Egypt](https://specstream.ai/data/clinical-trials/country/egypt) | 46 | October 27, 2026 |
| [Pakistan](https://specstream.ai/data/clinical-trials/country/pakistan) | 27 | October 8, 2026 |
| [Canada](https://specstream.ai/data/clinical-trials/country/canada) | 25 | October 21, 2026 |
| [Australia](https://specstream.ai/data/clinical-trials/country/australia) | 20 | October 30, 2026 |
| [Brazil](https://specstream.ai/data/clinical-trials/country/brazil) | 11 | November 2, 2026 |
| [United Kingdom](https://specstream.ai/data/clinical-trials/country/united-kingdom) | 10 | September 10, 2026 |
| [Spain](https://specstream.ai/data/clinical-trials/country/spain) | 8 | October 29, 2026 |
| [Indonesia](https://specstream.ai/data/clinical-trials/country/indonesia) | 7 | July 23, 2026 |
| [Thailand](https://specstream.ai/data/clinical-trials/country/thailand) | 7 | March 9, 2026 |
| [Greece](https://specstream.ai/data/clinical-trials/country/greece) | 7 | February 13, 2026 |
| [Italy](https://specstream.ai/data/clinical-trials/country/italy) | 6 | May 11, 2026 |
| [Israel](https://specstream.ai/data/clinical-trials/country/israel) | 5 | July 30, 2026 |
| [Denmark](https://specstream.ai/data/clinical-trials/country/denmark) | 5 | May 26, 2026 |
| [Austria](https://specstream.ai/data/clinical-trials/country/austria) | 5 | April 6, 2026 |
| [France](https://specstream.ai/data/clinical-trials/country/france) | 4 | September 10, 2026 |
| [Poland](https://specstream.ai/data/clinical-trials/country/poland) | 4 | August 24, 2026 |
| [South Africa](https://specstream.ai/data/clinical-trials/country/south-africa) | 4 | August 3, 2026 |
| [Germany](https://specstream.ai/data/clinical-trials/country/germany) | 4 | July 23, 2026 |
| [Turkey (Türkiye)](https://specstream.ai/data/clinical-trials/country/turkey-t-rkiye) | 4 | July 17, 2026 |
| [Hong Kong](https://specstream.ai/data/clinical-trials/country/hong-kong) | 4 | January 29, 2026 |
| [Netherlands](https://specstream.ai/data/clinical-trials/country/netherlands) | 4 | December 19, 2025 |
| [Jordan](https://specstream.ai/data/clinical-trials/country/jordan) | 3 | October 6, 2026 |
| [New Zealand](https://specstream.ai/data/clinical-trials/country/new-zealand) | 3 | June 26, 2026 |

## Where the register publishes

- [ClinicalTrials.gov](https://clinicaltrials.gov/)
- [ClinicalTrials.gov API](https://clinicaltrials.gov/data-api/api)

Source: [ClinicalTrials.gov API v2 (U.S. National Library of Medicine)](https://clinicaltrials.gov/data-api/api). U.S. government data; ClinicalTrials.gov terms of use. Studies are as their sponsors registered them on ClinicalTrials.gov, read through its API. Condition groups are the MeSH terms ClinicalTrials.gov assigns to each study's conditions; a study with several is in several groups. Sponsor class is the register's class of the lead sponsor. The central contact is in the full list only as the record prints it.

Free to reuse with credit to SpecStream under [CC BY 4.0](https://creativecommons.org/licenses/by/4.0/).