# Insulin Resistance trials: 300 new since Nov 2024

Updated November 9, 2026.

300 clinical studies in Insulin Resistance were first posted on ClinicalTrials.gov from November 14, 2024 to November 9, 2026; 27 have an industry sponsor and 166 are recruiting or about to. The newest, NCT07926152, was posted on November 9, 2026: Exercise and Protein to Reduce Muscle Loss During GLP-1-Based Treatment in Type 2 Diabetes (German Diabetes Center).

## The full list

New Insulin Resistance clinical trials: 300 rows for $15, first posted on ClinicalTrials.gov from November 12, 2024 to November 9, 2026. Columns: NCT ID, Title, Sponsor, Sponsor class, Phase, Status, Conditions, Condition groups (MeSH), Interventions, Start date, First posted, Enrollment, Enrollment type, Location countries, Central contact, Contact phone, Contact email, Last update posted, Read on, Source. The new rows each week by email, about 13 rows a month: $19 a month. Pay by card with no account. Prices exclude VAT. CSV and Excel files with the columns this page does not show (central contact, contact phone, contact email, sponsor class, condition groups (MeSH), interventions and 5 more), which open on your screen as soon as the payment clears and come by email. The rows on this page are a sample.

Buy: https://specstream.ai/data/clinical-trials/condition/insulin-resistance

SpecStream is the live web data engine for teams and agents. It reads every new study on ClinicalTrials.gov each morning, and this page is that reading. Ask for the conditions, phases or countries you follow and each new trial arrives in your sheet, CRM, Slack or agent with the sponsor, the sites and the listed contact.

- New trials: 300
- Industry sponsored: 27
- Recruiting or not yet: 166
- Latest posted: November 9, 2026

## Newest trials

The newest 100 of 300, each linked to its record. The full list holds every one with the sponsor class, interventions, start date and the central contact as the record prints it.

| First posted | NCT ID | Title | Sponsor | Phase | Status | Conditions | Enrollment | Countries | Source |
| --- | --- | --- | --- | --- | --- | --- | --- | --- | --- |
| November 9, 2026 | NCT07926152 | Exercise and Protein to Reduce Muscle Loss During GLP-1-Based Treatment in Type 2 Diabetes | German Diabetes Center | Not applicable | Not yet recruiting | Type 2 Diabetes (T2DM), Obesity & Overweight, Sarcopenia | 94 | Germany | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07926152) |
| November 9, 2026 | NCT07925801 | Relacorilant in Patients With Poorly Controlled Type 2 Diabetes and Autonomous Cortisol Secretion | The University of Texas Health Science Center at San Antonio | Phase 1/2 | Not yet recruiting | Type 2 Diabetes, Hypercortisolism | 34 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07925801) |
| November 6, 2026 | NCT07921940 | Effect of Probiotics on Insulin Sensitivity in Overweight and Obese Pregnancy | Medical University of Vienna | Not applicable | Active not recruiting | Obesity & Overweight, Gestational Diabetes Mellitus (GDM), Insulin Resistance, Maternal Obesity Complicating Pregnancy | 40 | Austria | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07921940) |
| November 4, 2026 | NCT07917364 | Asprosin and miRNA Expression in Young Women With Metabolic Syndrome | University of Applied Sciences in Nowy Targ | Observational | Recruiting | Metabolic Syndrome, Insulin Resistance, Obesity, Abdominal, Dyslipidemias | 110 | Poland | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07917364) |
| November 3, 2026 | NCT07913685 | The Effect of Liraglutide on Body Weight, Body Composition, Ectopic Lipid Accumulation and Insulin Sensitivity in Subjects With Overweight... | Medical University of Bialystok | Phase 4 | Completed | Obesity & Overweight | 83 | Poland | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07913685) |
| October 20, 2026 | NCT07884058 | IGOB131 As A GLP-1 Modulator For Metabolic Disorders In Adults With Obesity | University of Yaounde 1 | Phase 2 | Not yet recruiting | Obesity & Overweight | 80 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07884058) |
| October 15, 2026 | NCT07874945 | Peripheral Vascular Effects of Insulin in Obesity | University of Missouri-Columbia | Early phase 1 | Not yet recruiting | Obesity (BMI\>30), Insulin Resistance | 64 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07874945) |
| October 8, 2026 | NCT07865923 | Clinical Trial for the Study of Stress and Exercise Impact on Glucose Levels and Additional Physiological Signals. Stress, Insulin and... | National Council of Scientific and Technical Research, Argentina | Not applicable | Completed | Type 1 Diabetes (T1D) | 5 | Argentina | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07865923) |
| October 8, 2026 | NCT07865351 | Whole-Food Magnesium for Mental and Cardiometabolic Health | George Mason University | Not applicable | Not yet recruiting | Elevated Blood Glucose | 45 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07865351) |
| October 7, 2026 | NCT07862712 | Assessing Trauma-related Links Between Affective and Metabolic Systems | VA Office of Research and Development | Phase 4 | Not yet recruiting | Posttraumatic Stress Disorder, Metabolic Syndrome, Insulin Resistance | 70 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07862712) |
| October 6, 2026 | NCT07861191 | RESET-INSPIRE Study: Insulin Sensitivity & Population Intervention With Real-time Evaluation Using CGM | National University Health System, Singapore | Observational | Recruiting | Diabete Mellitus, MASLD | 270 | Singapore | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07861191) |
| October 2, 2026 | NCT07854782 | Trial to Evaluate ALN-CIDEB in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) | Regeneron Pharmaceuticals | Phase 3 | Recruiting | Metabolic Dysfunction-Associated Steatotic Liver Disease, MASLD | 1,500 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07854782) |
| October 2, 2026 | NCT07854002 | Multimodal Risk Factor Graph Mapping, Metabolic Subtyping, and Digital Intelligent Chronic Disease Management for Prediabetes: An... | Nanjing Medical University | Observational | Not yet recruiting | Prediabetes, Prediabetes (Insulin Resistance, Impaired Glucose Tolerance), Impaired Fasting Glucose, Impaired Glucose... | 30,000 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07854002) |
| October 2, 2026 | NCT07853898 | Effects of Pistachios on Postprandial Metabolic Responses in Adults With Overweight or Obesity | St. Louis University | Not applicable | Recruiting | Obesity / Overweight | 28 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07853898) |
| September 29, 2026 | NCT07847684 | Effects of Hourly Stair-Climbing Exercise Snacks on Metabolic and Vascular Health in Adults With Prediabetes | St. Louis University | Not applicable | Recruiting | Prediabetes | 20 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07847684) |
| September 28, 2026 | NCT07844785 | Metabolic and Hormonal Parameters in Women With Polyendocrine Metabolic Ovarian Syndrome | Istinye University | Observational | Not yet recruiting | Polycystic Ovary Syndrome, Polycystic Ovary Syndrome (PCOS) Women, Fetuin-A, Serum Biomarkers, Insulin Resistance | 80 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07844785) |
| September 25, 2026 | NCT07843082 | Exercise and Tissue-Specific Insulin Sensitivity in South Asian and Nordic Women With Previous Gestational Diabetes | Oslo University Hospital | Not applicable | Completed | Diabetes, Obesity & Overweight | 43 | Norway | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07843082) |
| September 23, 2026 | NCT07836088 | A Clinical Study on Using Multimodal Ultrasound to Assess Muscle Mass in Metabolic Diseases | Zhangzhou Municipal Hospital | Observational | Recruiting | Metabolic Syndrome, Obesity, Sarcopenia, Type 2 Diabetes | 320 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07836088) |
| September 22, 2026 | NCT07833397 | Moringa Leaf Powder for Prediabetes | Maranatha Christian University | Not applicable | Completed | Prediabetes, Prediabetes (Insulin Resistance, Impaired Glucose Tolerance) | 114 | Indonesia | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07833397) |
| September 21, 2026 | NCT07832071 | Phenolic Dependent And Independent Effects Of Whole Grain Sorghum On Immunometabolism | University of Nebraska Lincoln | Not applicable | Not yet recruiting | Dietary Intervention, Gut Microbiota, Insulin Sensitivity/Resistance, Obesity & Overweight | 30 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07832071) |
| September 21, 2026 | NCT07830121 | Very-Low-Carbohydrate Diet for Prediabetes and Obesity | Universiti Teknologi Mara | Not applicable | Completed | Prediabetes, Obesity / Overweight, VERY LOW CARBOHYDRATE DIET | 33 | Malaysia | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07830121) |
| September 15, 2026 | NCT07821086 | Effects of Estrogen Therapy on Lipid Metabolism and Insulin Sensitivity in Hypogonadal Women | Khyber Medical University Peshawar | Not applicable | Active not recruiting | Female Hypogonadism | 30 | Pakistan | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07821086) |
| September 8, 2026 | NCT07806656 | Acupuncture for Insulin Resistance in Women With Polycystic Ovary Syndrome | Peking University Third Hospital | Not applicable | Not yet recruiting | Polycystic Ovary Syndrome | 204 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07806656) |
| September 8, 2026 | NCT07806448 | Impact of Asprosin and Neuregulin 4 on Metabolic Parameters, Anthropometric Indices and Body Composition After Laparoscopic Sleeve... | General Committee of Teaching Hospitals and Institutes, Egypt | Observational | Completed | Bariatric Sleeve Gastrectomy | 160 | Egypt | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07806448) |
| September 3, 2026 | NCT07802275 | Postprandial Glucose Kinetics After Carbohydrate Restriction | Azienda Ospedaliero, Universitaria Pisana | Not applicable | Completed | Prediabetes, Obesity & Overweight, Diet Interventions, Carbohydrate Metabolism | 29 | Italy | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07802275) |
| September 3, 2026 | NCT07802262 | Prenatal Exercise and Glucose Regulation | University of Central Arkansas | Not applicable | Recruiting | Gestational Diabetes Mellitus, Gestational Diabetes Mellitus in Pregnancy, Insulin Resistance | 23 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07802262) |
| August 31, 2026 | NCT07793838 | Metformin Effects on Metabolic, Vitamin B12, Iron, Erythropoietin, and Hematological Parameters in Women With PCOS | Jerash Private University | Phase 4 | Completed | Polycystic Ovary Syndrome (PCOS) Women | 400 | Jordan | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07793838) |
| August 31, 2026 | NCT07793747 | Serum Asprosin, Metabolic Syndrome, and Cardiometabolic Risk in Rheumatoid Arthritis | Assiut University | Observational | Not yet recruiting | Rheumatoid Arthritis, Metabolic Syndrome, Cardiovascular Diseases | 75 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07793747) |
| August 27, 2026 | NCT07791394 | Does Estrogen Blunt the Effects of Exercise Training on Glycemic Control | University of Waterloo | Not applicable | Not yet recruiting | To Determine Whether Estrogen Influences the Effects of Training on Glycemic Control and Insulin Sensitivity | 24 | Canada | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07791394) |
| August 25, 2026 | NCT07785518 | Prevalenza Della Insulino Resistenza e Correlate Malattie Cardiovascolari Nella città di Napoli | Comune di Napoli | Observational | Completed | Insulin Resistance Syndrome, Cardio Vascular Disease, Prevalence | 123,752 | Italy | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07785518) |
| August 21, 2026 | NCT07780513 | Genetics of Skeletal Muscle Insulin Resistance | The University of Texas Health Science Center at San Antonio | Not applicable | Recruiting | Insulin Stimulated | 100 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07780513) |
| August 21, 2026 | NCT07779850 | Myo-Inositol for Ovarian Stimulation and ICSI Outcomes in Women With PCOS | Kafrelsheikh University | Not applicable | Completed | Polycystic Ovary Syndrome | 88 | Egypt | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07779850) |
| August 21, 2026 | NCT07778524 | Alpelisib Challenge Test (ACT) | Columbia University | Phase 1 | Recruiting | Insulin Resistance, Type 2 Diabetes, Obesity & Overweight, Healthy Adult Participants | 15 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07778524) |
| August 20, 2026 | NCT07775326 | Dietary Macronutrients and Metabolic Markers | The Jerzy Kukuczka Academy of Physical Education in Katowice | Not applicable | Completed | Ketogenic Diet, Thyroid Function, Insulin Resistance, Obesity Overweight | 120 | Poland | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07775326) |
| August 19, 2026 | NCT07774208 | FABP4 Response After Roux-en-Y Gastric Bypass | Istanbul University | Observational | Completed | Obesity (BMI\>30), Obesity (BMI \> 35), Insulin Resistance, Bariatric Surgery, Bariatric Surgery (Gastric Bypass) | 28 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07774208) |
| August 18, 2026 | NCT07770711 | Inositol and Metformin Administration in Mediterranean Diet and Low-Carbohydrate Diets in Women With PCOS | Dicle University | Not applicable | Recruiting | PCOS (Polycystic Ovary Syndrome), Insulin Resistance, Obesity (BMI\>30) | 90 | Turkey (Türkiye) | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07770711) |
| August 18, 2026 | NCT07770282 | Efficacy and Safety of Semaglutide Versus Placebo on Cardiometabolic Profile in Patients With Schizophrenia With Metabolic Syndrome | All India Institute of Medical Sciences, Bhubaneswar | Phase 3 | Not yet recruiting | Schizophrenia Disorder, Metabolic Syndrome, Antipsychotic-induced Weight Gain, Cardiovascular Risk, Insulin Resistance | 600 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07770282) |
| August 17, 2026 | NCT07768657 | Improvement in Hepatic Function Through Sumac (Rhus Coriaria L.) Supplement Along With a Calorie-restricted Diet for the Management of... | University of Lahore | Not applicable | Completed | Liver Biomarkers, Lipid Profile, Glucose, Insulin | 102 | Pakistan | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07768657) |
| August 13, 2026 | NCT07763626 | Gdue Plus a Hypocaloric Mediterranean Diet in Adults With MASLD | University of Genova | Not applicable | Completed | Metabolic Dysfunction-Associated Steatotic Liver Disease, Metabolic Syndrome | 112 | Italy | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07763626) |
| August 12, 2026 | NCT07759674 | Relationship Between Metformin Treatment, Anemia, and Erythropoietin Levels in Women With Polycystic Ovary Syndrome in Jordan | Jerash Private University | Phase 4 | Completed | Polycystic Ovary Syndrome (PCOS) Women, Insulin Resistance Syndrome | 25 | Jordan | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07759674) |
| August 10, 2026 | NCT07756294 | Restoring Vascular and Insulin Function To Augment Anti-Amyloid Therapy in Alzheimer's Disease | Wake Forest University Health Sciences | Phase 2 | Not yet recruiting | Alzheimer Disease | 30 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07756294) |
| August 7, 2026 | NCT07753018 | Effects of Curcumin-Piperine Supplementation in Fibromyalgia | Ain Shams University | Phase 2 | Not yet recruiting | Fibromyalgia (FM) | 80 | Egypt | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07753018) |
| August 3, 2026 | NCT07743073 | The Effects of Ceylon Cinnamon (Cinnamomum Verum) Supplementation on Blood Glucose, Lipid Profile Levels, Body Mass Index, and Pain... | JAWAD AHMAD ABU-SHENNAR | Not applicable | Recruiting | Painful Diabetic Peripheral Neuropathy | 164 | Jordan | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07743073) |
| July 30, 2026 | NCT07736079 | Evaluation of Serum Preptin Levels in Patients With Polycystic Ovary Syndrome | GÜLDEN ANATACA | Observational | Not yet recruiting | Polycystic Ovary Syndrome (PCOS), Insulin Resistance | 60 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07736079) |
| July 29, 2026 | NCT07734870 | Tirzepatide for Treatment of CCCA | Johns Hopkins University | Phase 2 | Recruiting | Central Centrifugal Cicatricial Alopecia (CCCA) | 20 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07734870) |
| July 29, 2026 | NCT07734558 | Evaluation of Neuregulin-4 (NRG4) Levels in Obese and Non-Obese Patients With Type 2 Diabetes Mellitus | GÜLDEN ANATACA | Observational | Not yet recruiting | Type 2 Diabetes Mellitus (T2DM), Obesity Type 2 Diabetes Mellitus, Insulin Resistance | 125 | Turkey (Türkiye) | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07734558) |
| July 27, 2026 | NCT07729280 | Impact of Preoperative Oral Carbohydrate Loading on Insulin Resistance in Pediatric Cardiac Surgery Patients | Rifdhani Fakhrudin Nur | Not applicable | Not yet recruiting | Cardiac Surgery, Insulin Resistance, Pediatric Cardiac Surgery | 44 | Indonesia | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07729280) |
| July 27, 2026 | NCT07728162 | Cold Spray for Insulin-Injection Pain in the Emergency Department | Abant Izzet Baysal University | Not applicable | Completed | Pain, Diabetes Mellitus | 100 | Turkey (Türkiye) | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07728162) |
| July 24, 2026 | NCT07724522 | Prebiotic Inulin for Late-Reproductive Individuals | George Washington University | Not applicable | Recruiting | Obesity & Overweight, Perimenopausal Women, Prebiotics, Inulin, Muscle, Skeletal, Cardiovascular Diseases (CVD)... | 27 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07724522) |
| July 23, 2026 | NCT07723391 | Effect of Preoperative Carbohydrate Loading on Serum Lactate Levels in Patients Undergoing Donor Hepatectomy | Shifa International Hospital | Not applicable | Completed | Donor Hepatectomy, Serum Lactate, Preoperative Carbohydrate Loading | 70 | Pakistan | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07723391) |
| July 22, 2026 | NCT07719296 | HIIT, Cardiorespiratory Fitness, and Metabolic Health in Healthy Young Adults | High Institute of Sports and Physical Education of Kef | Not applicable | Completed | Metabolic Health, Cardio Respiratory Fitness | 29 | Tunisia | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07719296) |
| July 17, 2026 | NCT07712068 | Effects of Exercise Sequence and Meal Sequence on Weight Management Among Children and Adolescents With Overweight or Obesity: The STEP... | Peking University | Not applicable | Not yet recruiting | Obesity & Overweight, Insulin Resistance, Inflamation | 480 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07712068) |
| July 17, 2026 | NCT07711587 | Diaplex and Glycemic Control | Standard Process Inc. | Not applicable | Not yet recruiting | Insulin Sensitivity, Healthy Adult | 40 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07711587) |
| July 14, 2026 | NCT07703371 | Kodo Millet Porridge and Its Effects on Gut Health and Metabolic Syndrome | JSS MEDICAL COLLEGE, JSS ACADEMY OF HIGHER EDUCATION AND RESEARCH | Not applicable | Recruiting | Obesity & Overweight, Metabolic Syndrome, Gut Dysbiosis, Insulin Resistance, Dyslipidemia | 50 | India | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07703371) |
| July 14, 2026 | NCT07702695 | A Mediterranean Diet-Based Culinary Intervention in Adults With Metabolic Syndrome | Fundacion Clinic per a la Recerca Biomédica | Not applicable | Not yet recruiting | Metabolic Syndrome | 120 | Spain | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07702695) |
| July 14, 2026 | NCT07702669 | Modified Huanglian Wendan Decoction for Metabolic Syndrome | First Affiliated Hospital of Heilongjiang Chinese Medicine University | Not applicable | Completed | Metabolic Syndrome | 180 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07702669) |
| July 14, 2026 | NCT07701005 | Non-Invasive Hepatic and Metabolic Index Changes After Incretin Therapy in Overweight/Obesity | Goztepe Prof Dr Suleyman Yalcın City Hospital | Observational | Completed | Steatosis of Liver, Metabolic Liver Injury, Obesity, Overweight, Insulin Resistance | 154 | Turkey (Türkiye) | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07701005) |
| July 10, 2026 | NCT07696247 | Effect of Agave Inulin Supplementation on Metabolic Profile and Intestinal Abundance of Bifidobacterium and Lactobacillaceae in Adults With... | Universidad Autonoma de Queretaro | Not applicable | Active not recruiting | Type 2 Diabetes, Gut Microbiota, Insulin Resistance, Metabolic Syndrome, Prebiotic | 43 | Mexico | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07696247) |
| July 8, 2026 | NCT07690163 | DIabetes GLycemic Assessment in Newly Confirmed Episodes | Nazarii Kobyliak | Not applicable | Recruiting | Type 2 Diabetes (T2DM), Obesity Type 2 Diabetes Mellitus, Obesity & Overweight, Insulin Resistance | 80 | Ukraine | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07690163) |
| July 6, 2026 | NCT07686029 | Use of Maltodextrins in the ERAS Preoperative Fasting Protocol in Pediatric Surgery | Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo di Alessandria | Not applicable | Recruiting | Preoperative Care, Anxiety, Pediatric Surgery | 200 | Italy | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07686029) |
| July 6, 2026 | NCT07685080 | "Effectiveness of Supervised and Unsupervised mHealth-based Exercise Interventions on Clinical Outcomes in Adults With Type 2 Diabetes and... | Escuela Universitaria de Osuna | Not applicable | Not yet recruiting | Diabetes Mellitus, Type 2, Obesity, Insulin Resistance, Sedentary Behaviors, mHealth, Physical Exercise, Primary Care... | 126 | Spain | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07685080) |
| July 6, 2026 | NCT07682857 | Effects of an Arabinoxylan-enriched Rusk on Postprandial Glucose, Insulin, Glucagon-like Peptide-1 and Appetite Responses | University of Turin, Italy | Not applicable | Completed | Healthy Adult Participants | 10 | Italy | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07682857) |
| July 2, 2026 | NCT07682077 | Diabetes, Insulin, Gut, Enteric Supplementation Trial | University of New Brunswick | Not applicable | Recruiting | Gestational Diabetes Mellitus (GDM), Blood Glucose, Insulin Resistance, Diabetes, Gut Microbiome, Gut Metabolites | 60 | Canada | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07682077) |
| July 1, 2026 | NCT07678736 | The Muscle Monitor: Early Skeletal Muscle Indicators of Insulin Resistance and Cardiometabolic Risk | University Ghent | Observational | Recruiting | Insulin Resistance, Insulin Resistance and Type 2 Diabetes, Cardiometabolic Risk Factors, Physical Activity, Muscle... | 250 | Belgium | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07678736) |
| June 30, 2026 | NCT07675499 | Exercise and Intranasal Insulin in Type 2 Diabetes | Rutgers, The State University of New Jersey | Phase 2/3 | Recruiting | Type 2 Diabetes, Insulin Sensitivity/Resistance, Cognition, Brain Blood Flow | 60 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07675499) |
| June 26, 2026 | NCT07670871 | Exocrine-Endocrine Pancreatic Crosstalk: Precision Pathways to Reframe Diabetes Pathophysiology | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | Observational | Not yet recruiting | Type 2 Diabetes Mellitus (T2DM), Chronic Pancreatitis, Prediabetes, Pancreatic Neoplasms | 440 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07670871) |
| June 26, 2026 | NCT07670572 | Think-Find-Solve Activities for Insulin Self-Management in Type 1 Diabetes | Marmara University | Not applicable | Recruiting | Type 1 Diabetes, Children, Activity, Insulin, Self Management, Parent | 40 | Turkey (Türkiye) | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07670572) |
| June 24, 2026 | NCT07664501 | The Simplified Total-body Resistance Exercise for Muscular Hypertrophy for Diabetic Population (D-STORM) | Universiti Teknologi Mara | Not applicable | Not yet recruiting | Type 2 Diabetes Mellitus (T2DM), Sarcopenia, Insulin Resistance | 56 | Malaysia | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07664501) |
| June 22, 2026 | NCT07659444 | Metformin Withdrawal In Metabolic Syndrome | University of Castilla-La Mancha | Not applicable | Active not recruiting | Metabolic Syndrome (MetS), Glucose Intolerance | 21 | Spain | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07659444) |
| June 17, 2026 | NCT07654062 | Mazdutide for Adults With Prediabetes: A Randomized, Double-Blind, Placebo-Controlled Trial (DREAM-PRE) | Shandong Provincial Hospital | Phase 4 | Not yet recruiting | Prediabetes, Impaired Fasting Glucose, Impaired Glucose Tolerance (Prediabetes) | 150 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07654062) |
| June 17, 2026 | NCT07653464 | Interplay of Central and Peripheral Vascular Effects of Insulin in Obesity | University of Missouri-Columbia | Early phase 1 | Not yet recruiting | Obesity (BMI\>30), Insulin Resistance | 64 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07653464) |
| June 16, 2026 | NCT07651254 | Effects of a 12-week Supervised Exercise Program Post Bariatric Surgery on Body Composition, Muscle Strength, and Insulin Resistance | Laval University | Not applicable | Completed | Bariatric Surgery, Exercise, Body Composition Changes | 61 | Canada | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07651254) |
| June 10, 2026 | NCT07638059 | The Influence of Obesity and Insulin Sensitivity on Reward Processing and Decision Making | Virginia Polytechnic Institute and State University | Not applicable | Not yet recruiting | Adiposity, Insulin Sensitivity/Resistance, Decision-Making, Reward Learning | 50 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07638059) |
| June 8, 2026 | NCT07633704 | Protective Effect of Exercise on Acute High-fat Overfeeding | George Washington University | Not applicable | Completed | Insulin Sensitivity/Resistance | 50 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07633704) |
| June 4, 2026 | NCT07626658 | Food-i-Sense Analytics: Integrating AI Into Continuous Glucose Monitoring Data Analysis for Precision Nutrition. | IMDEA Food | Observational | Recruiting | Prediabetes (Insulin Resistance, Impaired Glucose Tolerance), Artificial Intelligence Mobile Application | 471 | Spain | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07626658) |
| June 3, 2026 | NCT07624500 | Food and Metabolism Study | Clinical Nutrition Research Center, Illinois Institute of Technology | Not applicable | Recruiting | Prediabetes, Insulin Resistance, Triglycerides, Lipids Metabolism | 82 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07624500) |
| June 1, 2026 | NCT07618663 | Personalized Meal Timing and Walking Based on Glucose Patterns in Adults With Prediabetes | Shifa International Hospital | Not applicable | Completed | Prediabetes, Prediabetes (Insulin Resistance, Impaired Glucose Tolerance), Prediabetes or Diabetes | 105 | Pakistan | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07618663) |
| June 1, 2026 | NCT07618117 | Improving Sleep Health and Circadian Timing to Support Cardiometabolic Health in Adolescents | University of Colorado, Denver | Not applicable | Recruiting | Overweight Adolescents, Sleep, Insulin Sensitivity | 60 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07618117) |
| June 1, 2026 | NCT07616570 | Serum Adipokines and Metabolic Parameters With Hormone Replacement in Newly Diagnosed Hypothyroidism | Başakşehir Çam & Sakura City Hospital | Observational | Completed | Hypothyroidism, Primary Hypothyroidism, Metabolic Syndrome | 88 | Turkey (Türkiye) | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07616570) |
| May 27, 2026 | NCT07609004 | Influence of Tea Consumption on Human Glycemic Response | National University of Singapore | Not applicable | Active not recruiting | Glycaemic Response | 20 | Singapore | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07609004) |
| May 26, 2026 | NCT07606872 | Validation of the Snouda Metabolic Score for Phenotyping and Guiding Reversal in Type 2 Diabetes | Salah Snouda | Not applicable | Enrolling by invitation | Type 2 Diabetes Mellitus (T2DM), Insulin Resistance, Metabolic Syndrome | 150 | United Kingdom | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07606872) |
| May 22, 2026 | NCT07603739 | Eating Almonds Before a Meal to Control Blood Sugar | Pennington Biomedical Research Center | Not applicable | Recruiting | Glucose Control, Prediabetes (Insulin Resistance, Impaired Glucose Tolerance), Precision Medicine, Nutrition | 25 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07603739) |
| May 22, 2026 | NCT07603505 | Effect of NAE on Polycystic Ovarian Syndrome (PCOS) | Jinnah Sindh Medical University | Phase 1 | Completed | Polycystic Ovarian Syndrome (PCOS), Infertility, Metabolic Disorders | 116 | Pakistan | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07603505) |
| May 22, 2026 | NCT07603284 | Continuous Glucose Monitoring By DExcom iN PEople Followed for Type 2 DIabeTes on Insulin Therapy in the Kingdom of Saudi Arabia | DexCom, Inc. | Phase 4 | Active not recruiting | Type 2 Diabetes on Insulin | 200 | Saudi Arabia | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07603284) |
| May 20, 2026 | NCT07599982 | Safety Evaluation of MODI, an Insulin Titration Algorithm, in Adults With Diabetes | DreaMed Diabetes | Not applicable | Recruiting | Type 1 Diabetes (T1D), Type 2 Diabetes (T2D) | 102 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07599982) |
| May 20, 2026 | NCT07599072 | PREdiabetes GLycemic Impact and Data Evaluation | Nazarii Kobyliak | Not applicable | Recruiting | Pre Diabetic, Obesity & Overweight, Insulin Resistance | 80 | Ukraine | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07599072) |
| May 15, 2026 | NCT07589374 | Cf-PWV and TyG Index Study | Hospital de Base | Observational | Not yet recruiting | Hypertension, Insulin Resistance Syndrome, Arterial Stiffness, Cardiovascular Risk, Blood Pressure Variability | 800 | Brazil | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07589374) |
| May 14, 2026 | NCT07586969 | Modulation of Hyperandrogenic Anovulation Through Fenugreek Seeds | University of Lahore | Not applicable | Completed | Poly Cystic Ovary Syndrome | 70 | Pakistan | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07586969) |
| May 13, 2026 | NCT07583043 | Effect of Diet Supplementation With Amaranth Protein on Mexican Children With Overweight and Obesity | Instituto Potosino De Investigacion Cientifica Y Tecnologica AC | Not applicable | Completed | Overweight and Obesity | 56 | Mexico | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07583043) |
| May 12, 2026 | NCT07582471 | Insulin Versus Oral Hypoglycemic Agents in Gestational Diabetes Mellitus | Dr Mudassar Saeed Pansota | Not applicable | Completed | Gestational Diabetes Mellitus (GDM) | 60 | Pakistan | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07582471) |
| May 8, 2026 | NCT07575438 | Effects of Different Fish Oil Types on Type 2 Diabetes Risk Factors in High-Risk Adults | May Faraj, PDt, PhD | Phase 2 | Recruiting | Type 2 Diabetes, Prediabetes (Insulin Resistance, Impaired Glucose Tolerance), Prediabetes / Type 2 Diabetes, Obesity &... | 84 | Canada | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07575438) |
| May 7, 2026 | NCT07573917 | Improving Insulin Sensitivity in Patients With Type 2 Diabetes Via Repeated Cold-induced Shivering Thermogenesis | Université de Sherbrooke | Not applicable | Recruiting | Type 2 Diabetes | 15 | Canada | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07573917) |
| May 5, 2026 | NCT07566884 | Safety and Tolerance of a Novel Three-Strain Probiotic in Healthy Adults | Pendulum Therapeutics | Not applicable | Active not recruiting | Healthy Adults | 30 | Ireland | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07566884) |
| May 4, 2026 | NCT07565727 | Cardiometabolic Disease and Substrate Metabolism | University of Tennessee Graduate School of Medicine | Observational | Recruiting | Preeclampsia, Gestational Diabetes Mellitus (GDM), Preeclampsia (PE), Preeclampsia (PE) Risk, Gestational Diabetes... | 50 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07565727) |
| April 28, 2026 | NCT07553325 | Risk-informed Shared-decision Making Engagement Strategy for Patients With Prediabetes | Johns Hopkins University | Not applicable | Recruiting | Prediabetes, Prediabetes (Insulin Resistance, Impaired Glucose Tolerance) | 120 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07553325) |
| April 27, 2026 | NCT07551960 | Pilot Validation of the STELA Preventive Medicine Platform to Reduce Modifiable Health Risk Factors in Adults (CPM-STELA) | Nemocnice AGEL Trinec-Podlesi a.s. | Not applicable | Enrolling by invitation | Cardiovascular Risk Factors, Insulin Resistance, Obesity, Dyslipidemias, Metabolic Syndrome | 100 | Czechia | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07551960) |
| April 27, 2026 | NCT07551947 | Insulin Resistance as a Predictor of Pulsed Field Ablation Success in Atrial Fibrillation (HOMA-PULSE) | Nemocnice AGEL Trinec-Podlesi a.s. | Observational | Enrolling by invitation | Atrial Fibrillation, Insulin Resistance, Catheter Ablation, Artificial Intelligence | 120 | Czechia | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07551947) |
| April 22, 2026 | NCT07546409 | Effects of Exogenous Ketones on Cognitive Function in Older Adults With Prediabetes? | University of Alabama at Birmingham | Not applicable | Recruiting | Prediabetes, Healthy (Controls) | 20 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07546409) |
| April 22, 2026 | NCT07545538 | Carbohydrate Loading in Lowering Perioperative Insulin Resistance in Pediatric Surgery | Gadjah Mada University | Not applicable | Enrolling by invitation | Insulin Resistance | 50 | Indonesia | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07545538) |
| April 21, 2026 | NCT07540949 | Rutazyme Lemon Fermented Product Capsules for Metabolic Function in Adults With Obesity | National Taiwan Sport University | Not applicable | Recruiting | Obesity, Metabolic Syndrome | 40 | Taiwan | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07540949) |

## Sponsors posting most

| Sponsor | New trials | Latest |
| --- | --- | --- |
| University of Missouri-Columbia | 4 | October 15, 2026 |
| Cairo University | 4 | February 25, 2026 |
| University of Colorado, Denver | 3 | June 1, 2026 |
| Chinese Medical Association | 3 | February 4, 2026 |
| University of Aarhus | 3 | January 22, 2026 |
| University of Virginia | 3 | January 20, 2026 |
| University of Jordan | 3 | April 4, 2025 |
| Jagiellonian University | 3 | January 27, 2025 |
| Gan & Lee Pharmaceuticals. | 3 | January 10, 2025 |
| The University of Texas Health Science Center at San Antonio | 2 | November 9, 2026 |
| St. Louis University | 2 | October 2, 2026 |
| Universiti Teknologi Mara | 2 | September 21, 2026 |
| Jerash Private University | 2 | August 31, 2026 |
| Columbia University | 2 | August 21, 2026 |
| Istanbul University | 2 | August 19, 2026 |
| University of Lahore | 2 | August 17, 2026 |
| Ain Shams University | 2 | August 7, 2026 |
| GÜLDEN ANATACA | 2 | July 30, 2026 |
| Johns Hopkins University | 2 | July 29, 2026 |
| Rifdhani Fakhrudin Nur | 2 | July 27, 2026 |

## By phase

| Phase | New trials | Latest |
| --- | --- | --- |
| [Not applicable](https://specstream.ai/data/clinical-trials/phase/not-applicable) | 183 | November 9, 2026 |
| [Observational](https://specstream.ai/data/clinical-trials/phase/observational) | 60 | November 4, 2026 |
| [Phase 2](https://specstream.ai/data/clinical-trials/phase/phase-2) | 13 | October 20, 2026 |
| [Phase 4](https://specstream.ai/data/clinical-trials/phase/phase-4) | 12 | November 3, 2026 |
| [Phase 3](https://specstream.ai/data/clinical-trials/phase/phase-3) | 11 | October 2, 2026 |
| [Phase 1](https://specstream.ai/data/clinical-trials/phase/phase-1) | 10 | August 21, 2026 |
| [Early phase 1](https://specstream.ai/data/clinical-trials/phase/early-phase-1) | 5 | October 15, 2026 |
| [Phase 1/2](https://specstream.ai/data/clinical-trials/phase/phase-1-2) | 4 | November 9, 2026 |
| [Phase 2/3](https://specstream.ai/data/clinical-trials/phase/phase-2-3) | 2 | June 30, 2026 |

## By country

| Country | New trials | Latest |
| --- | --- | --- |
| [United States](https://specstream.ai/data/clinical-trials/country/united-states) | 68 | November 9, 2026 |
| [China](https://specstream.ai/data/clinical-trials/country/china) | 21 | September 23, 2026 |
| [Turkey (Türkiye)](https://specstream.ai/data/clinical-trials/country/turkey-t-rkiye) | 17 | August 18, 2026 |
| [Canada](https://specstream.ai/data/clinical-trials/country/canada) | 15 | August 27, 2026 |
| [Spain](https://specstream.ai/data/clinical-trials/country/spain) | 14 | July 14, 2026 |
| [Egypt](https://specstream.ai/data/clinical-trials/country/egypt) | 11 | September 8, 2026 |
| [Pakistan](https://specstream.ai/data/clinical-trials/country/pakistan) | 10 | September 15, 2026 |
| [Denmark](https://specstream.ai/data/clinical-trials/country/denmark) | 10 | January 29, 2026 |
| [Indonesia](https://specstream.ai/data/clinical-trials/country/indonesia) | 9 | September 22, 2026 |
| [Italy](https://specstream.ai/data/clinical-trials/country/italy) | 9 | September 3, 2026 |
| [Poland](https://specstream.ai/data/clinical-trials/country/poland) | 7 | November 4, 2026 |
| [Mexico](https://specstream.ai/data/clinical-trials/country/mexico) | 7 | July 10, 2026 |
| [Germany](https://specstream.ai/data/clinical-trials/country/germany) | 6 | November 9, 2026 |
| [Jordan](https://specstream.ai/data/clinical-trials/country/jordan) | 6 | August 31, 2026 |
| [Taiwan](https://specstream.ai/data/clinical-trials/country/taiwan) | 6 | April 21, 2026 |
| [United Kingdom](https://specstream.ai/data/clinical-trials/country/united-kingdom) | 5 | May 26, 2026 |
| [Brazil](https://specstream.ai/data/clinical-trials/country/brazil) | 5 | May 15, 2026 |
| [France](https://specstream.ai/data/clinical-trials/country/france) | 5 | March 19, 2026 |
| [Singapore](https://specstream.ai/data/clinical-trials/country/singapore) | 4 | October 6, 2026 |
| [Chile](https://specstream.ai/data/clinical-trials/country/chile) | 4 | December 17, 2025 |
| [Austria](https://specstream.ai/data/clinical-trials/country/austria) | 3 | November 6, 2026 |
| [Czechia](https://specstream.ai/data/clinical-trials/country/czechia) | 3 | April 27, 2026 |
| [Switzerland](https://specstream.ai/data/clinical-trials/country/switzerland) | 3 | June 4, 2025 |
| [Malaysia](https://specstream.ai/data/clinical-trials/country/malaysia) | 2 | September 21, 2026 |
| [Tunisia](https://specstream.ai/data/clinical-trials/country/tunisia) | 2 | July 22, 2026 |

## Where the register publishes

- [ClinicalTrials.gov](https://clinicaltrials.gov/)
- [ClinicalTrials.gov API](https://clinicaltrials.gov/data-api/api)

Source: [ClinicalTrials.gov API v2 (U.S. National Library of Medicine)](https://clinicaltrials.gov/data-api/api). U.S. government data; ClinicalTrials.gov terms of use. Studies are as their sponsors registered them on ClinicalTrials.gov, read through its API. Condition groups are the MeSH terms ClinicalTrials.gov assigns to each study's conditions; a study with several is in several groups. Sponsor class is the register's class of the lead sponsor. The central contact is in the full list only as the record prints it.

Free to reuse with credit to SpecStream under [CC BY 4.0](https://creativecommons.org/licenses/by/4.0/).