# New Heart Failure clinical trials: 750 posted since Nov 2024

Updated November 9, 2026.

750 clinical studies in Heart Failure were first posted on ClinicalTrials.gov from November 12, 2024 to November 9, 2026; 136 have an industry sponsor and 533 are recruiting or about to. The newest, NCT07926958, was posted on November 9, 2026: Natriuresis With Acetazolamide or SGLT2 Inhibitors Added to Intravenous Loop Diuretics in Decompensated Heart... (Universidade do Porto).

## The full list

New Heart Failure clinical trials: 750 rows for $37.50, first posted on ClinicalTrials.gov from November 12, 2024 to November 9, 2026. Columns: NCT ID, Title, Sponsor, Sponsor class, Phase, Status, Conditions, Condition groups (MeSH), Interventions, Start date, First posted, Enrollment, Enrollment type, Location countries, Central contact, Contact phone, Contact email, Last update posted, Read on, Source. The new rows each week by email, about 30 rows a month: $19 a month. Pay by card with no account. Prices exclude VAT. CSV and Excel files with the columns this page does not show (central contact, contact phone, contact email, sponsor class, condition groups (MeSH), interventions and 5 more), which open on your screen as soon as the payment clears and come by email. The rows on this page are a sample.

Buy: https://specstream.ai/data/clinical-trials/condition/heart-failure

SpecStream is the live web data engine for teams and agents. It reads every new study on ClinicalTrials.gov each morning, and this page is that reading. Ask for the conditions, phases or countries you follow and each new trial arrives in your sheet, CRM, Slack or agent with the sponsor, the sites and the listed contact.

- New trials: 750
- Industry sponsored: 136
- Recruiting or not yet: 533
- Latest posted: November 9, 2026

## Newest trials

The newest 100 of 750, each linked to its record. The full list holds every one with the sponsor class, interventions, start date and the central contact as the record prints it.

| First posted | NCT ID | Title | Sponsor | Phase | Status | Conditions | Enrollment | Countries | Source |
| --- | --- | --- | --- | --- | --- | --- | --- | --- | --- |
| November 9, 2026 | NCT07926958 | Natriuresis With Acetazolamide or SGLT2 Inhibitors Added to Intravenous Loop Diuretics in Decompensated Heart Failure | Universidade do Porto | Phase 4 | Active not recruiting | Heart Failure, Acute Decompensated Heart Failure (ADHF) | 68 | Portugal | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07926958) |
| November 6, 2026 | NCT07922863 | MUTTON-HF Pilot Expansion | University of Pennsylvania | Phase 3 | Not yet recruiting | Heart Failure | 100 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07922863) |
| November 6, 2026 | NCT07921758 | The Role of Multidimensional Prognostic Index (MPI) in the Assessment of Elderly Patients underGoING Cardiac REHABilitation | Istituti Clinici Scientifici Maugeri SpA | Observational | Completed | Heart Failure, Acute Coronary Syndromes (ACS), Cardiac Surgery | 202 | Italy | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07921758) |
| November 4, 2026 | NCT07917052 | King's Theory-Based Multicomponent Interventions in Heart Failure Patient Rehabilitation | Saglik Bilimleri Universitesi | Not applicable | Not yet recruiting | Heart Failure, Cardiac Rehabilitation | 40 | Turkey (Türkiye) | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07917052) |
| November 3, 2026 | NCT07913204 | Evaluating a Digital Aid to Improve ICD Decisions | Stanford University | Not applicable | Recruiting | Shared Decision-making | 600 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07913204) |
| November 3, 2026 | NCT07912086 | 31P-MRS Myocardial Energetic Phenotyping and Prognosis Across the Cardiac Disease Spectrum | Chinese Academy of Medical Sciences, Fuwai Hospital | Observational | Recruiting | Cardiomyopathies, Heart Failure | 1,000 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07912086) |
| November 2, 2026 | NCT07910968 | SWitching to Appropriate Prescription in Cardiovascular-Kidney-Metabolic Syndrome | Kaiser Permanente | Not applicable | Not yet recruiting | Cardiovascular-kidney-metabolic Syndrome, Diabete Type 2, Chronic Kidney Disease, Heart Failure | 1,200 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07910968) |
| November 2, 2026 | NCT07910812 | Impact of a Tailored Digital Intervention on Sedentary Behaviour and Physical Health in Long-term Cardiac Rehabilitation Patients | University of Lisbon | Not applicable | Recruiting | Cardiovascular Diseases (CVD), Coronary Disease, Heart Failure, Cardiac Rehabilitation, Sedentary Behaviour | 64 | Portugal | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07910812) |
| November 2, 2026 | NCT07910084 | Notification Of High-Risk Veterans for Access to Heart Failure Prevention | Palo Alto Veterans Institute for Research | Not applicable | Not yet recruiting | Heart Failure | 250 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07910084) |
| October 30, 2026 | NCT07907640 | Real-world Effectiveness and Safety of Savagen (Sacubitril/Valsartan) in Malaysian HFrEF Patients | Sunway University | Observational | Not yet recruiting | Heart Failure With Reduced Ejection Fraction (HFrEF), Heart Failure | 80 | Malaysia | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07907640) |
| October 30, 2026 | NCT07906353 | Routine Magnesium Testing and Supplementation in Acute Heart Failure (MAG-HF) | University of Alberta | Not applicable | Not yet recruiting | Acute Heart Failure (AHF) | 260 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07906353) |
| October 29, 2026 | NCT07905443 | Bedside Ultrasound in the Emergency Department for Predicting Acute Heart Failure Outcomes | Sakarya University | Observational | Completed | Acute Heart Failure (AHF), Heart Failure | 128 | Turkey (Türkiye) | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07905443) |
| October 28, 2026 | NCT07902453 | Virtual Human Twins as Tools for Personalized Clinical Care in Heart Failure With Preserved Ejection Fraction: a Pilot Study | Assistance Publique - Hôpitaux de Paris | Not applicable | Not yet recruiting | Heart Failure | 60 | France | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07902453) |
| October 28, 2026 | NCT07901270 | Metabolic Changes in Heart Failure Patients Treated With Vericiguat | University of Salerno | Observational | Not yet recruiting | Heart Failure, Worsening Heart Failure, Heart Failure With Reduced Ejection Fraction | 30 | Italy | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07901270) |
| October 27, 2026 | NCT07896863 | Mobile Clinic-Supported, Village Doctor-Led Screening and Integrated Care for Atrial Fibrillation and Heart Failure Comorbidity in Rural... | Jiangsu Taizhou People's Hospital | Not applicable | Not yet recruiting | Atrial Fibrillation (AF), Heart Failure | 1,200 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07896863) |
| October 23, 2026 | NCT07891390 | Pilot Study to Determine the Optimal Protocol for Preoperative Transcutaneous Vagal Neurostimulation | Centre Hospitalier Universitaire de Saint Etienne | Not applicable | Not yet recruiting | Atrial Fibrillation (AF), Cerebral Vascular Accident (CVA), Heart Failure, Myocardial Infarction (MI) | 64 | France | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07891390) |
| October 22, 2026 | NCT07889076 | The Development and Optimization of a Cardiac Magnetic Resonance Imaging Protocol in a 3 Tesla Scanner | Wang . Jiun-Jie | Observational | Completed | Cardiac Failure | 120 | Taiwan | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07889076) |
| October 21, 2026 | NCT07886580 | Psychometric Evaluation of the Traditional Chinese Multidimensional Fatigue Inventory in Patients With Heart Failure | Kaohsiung Medical University | Observational | Not yet recruiting | Heart Failure, Fatigue Severity Scale | 400 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07886580) |
| October 21, 2026 | NCT07886489 | Donor Derived Cell Free DNA (Dd-cfDNA) as a Biomarker for Allograft Rejection in Heart Transplant Recipients | University of Aarhus | Observational | Enrolling by invitation | Heart Transplantation | 100 | Denmark, Norway | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07886489) |
| October 21, 2026 | NCT07885514 | Exercise, Mediterranean Diet and Inflammation in Heart Failure | Hospital Severo Ochoa | Not applicable | Not yet recruiting | Heart Failure, Heart Failure Preserved Ejection Fraction, Heart Failure, Diastolic (HFpEF), Chronic Inflammation | 214 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07885514) |
| October 21, 2026 | NCT07885488 | Screening Elderly Adults in Rural Communities for Heart Failure Using an NT-proBNP-Guided Strategy in China (SEARCH-HF) | Jiangsu Taizhou People's Hospital | Not applicable | Recruiting | Heart Failure | 2,532 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07885488) |
| October 20, 2026 | NCT07883369 | Development and Evaluation of a Disease-oriented Scenario Game to Promote ACP Among Older Adults and Family Caregivers | Taipei Veterans General Hospital, Taiwan | Not applicable | Not yet recruiting | Heart Failure, Older Adults (65 Years and Older), Family Caregivers, Life Support Treatment, Tabletop Game | 164 | Taiwan | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07883369) |
| October 20, 2026 | NCT07883317 | A First-in-Human Study to Evaluate the Safety and Efficacy of Left Ventricular Assist Device Combined With Exosome Therapy for Patients... | Yining Yang | Early phase 1 | Not yet recruiting | Heart Failure | 24 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07883317) |
| October 19, 2026 | NCT07880730 | Right Heart Injury Monitoring on ECMO | Papworth Hospital NHS Foundation Trust | Observational | Not yet recruiting | Acute Respiratory Distress Syndrome (ARDS), Acute Respiratory Failure (ARF), Right Heart Failure, Unspecified | 30 | United Kingdom | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07880730) |
| October 19, 2026 | NCT07880158 | Sequential Digital Intervention to Increase Influenza Vaccination in Patients With Heart Failure | Heart Health Research Center | Not applicable | Not yet recruiting | Heart Failure, Influenza Vaccination | 588 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07880158) |
| October 16, 2026 | NCT07878325 | Effects of a Specialized Diabetes and Heart Clinic and Detection of Unrecognized Heart Failure in People With Type 2 Diabetes and... | Odense University Hospital | Not applicable | Recruiting | Cardiovascular Disease, Cardiometabolic Diseases, Diabetes Type 2, Diabetes and Heart Failure, Heart Failure With... | 375 | Denmark | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07878325) |
| October 16, 2026 | NCT07877805 | Merlin Expanded ECG NSR | Abbott Medical Devices | Observational | Not yet recruiting | Heart Failure, Bradycardia | 50 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07877805) |
| October 14, 2026 | NCT07874386 | Wearable Tissue Oximetry During Arm Cuff Occlusion, Walking, and Standing Tests in Outpatients With Chronic Heart Failure | NIRSense Inc. | Observational | Completed | Heart Failure, Chronic Heart Failure | 50 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07874386) |
| October 13, 2026 | NCT07870395 | Voice-based Outcome Identification and Clinical Evaluation in Heart Failure | Noah Labs | Observational | Recruiting | Heart Failure, Chronic Heart Failure, Chronic Heart Disease | 450 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07870395) |
| October 13, 2026 | NCT07870369 | Cardiovascular Risk in Patients With Primary Hyperparathyroidism | Medical University of Sofia | Observational | Completed | Heart Failure, Atrial Fibrillation (AF), Arrhythmia, Coronary Artery Disease, Hypertension (HTN) | 77 | Bulgaria | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07870369) |
| October 8, 2026 | NCT07866859 | Common Femoral Vein-to-Artery Diameter Ratio for Detection of Elevated LVEDP | Burapha University | Observational | Recruiting | Acute Coronary Syndrome, Chronic Coronary Syndrome, Heart Failure | 105 | Thailand | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07866859) |
| October 8, 2026 | NCT07864558 | PrEcision Pacing in HFpEF: the PEP-HFpEF Trial | Tufts Medical Center | Not applicable | Recruiting | Heart Failure and Preserved Ejection Fraction, Heart Failure New York Heart Association Class III, Heart Failure New... | 36 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07864558) |
| October 7, 2026 | NCT07864363 | Rhythmic Auditory Stimulation in Heart Failure Patients | Necmettin Erbakan University | Not applicable | Active not recruiting | Heart Failure, Functional Capacity | 40 | Turkey (Türkiye) | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07864363) |
| October 7, 2026 | NCT07862933 | AI-Based Conversational Social Support for Older Adults With Heart Failure | Chang Gung University of Science and Technology | Not applicable | Recruiting | Heart Failure | 174 | Taiwan | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07862933) |
| October 7, 2026 | NCT07862738 | Inspiratory Muscle Training in Hospitalized Patients With Heart Failure Awaiting Advanced Therapies | NYU Langone Health | Not applicable | Not yet recruiting | Heart Failure, Heart Failure New York Heart Association Class III, Heart Failure New York Heart Association Class IV | 30 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07862738) |
| October 6, 2026 | NCT07861035 | A Phase I Study of Allogeneic Myocardium-Derived Mesenchymal Stem Cells (HB1011) in Patients With Ischemic Cardiomyopathy | HieraBio Inc. | Phase 1 | Recruiting | Ischemic Cardiomyopathy | 12 | South Korea | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07861035) |
| October 5, 2026 | NCT07858799 | Early Feasibility Study of the Edwards APTURE Transcatheter Shunt System | Edwards Lifesciences | Not applicable | Recruiting | Heart Failure | 15 | Germany | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07858799) |
| October 5, 2026 | NCT07858318 | Accelerated (Intensive) Cardiac Training for Heart Failure Patients | Washington University School of Medicine | Not applicable | Not yet recruiting | Cardiac Rehabilitation, Heart Failure | 20 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07858318) |
| October 5, 2026 | NCT07857772 | This Will be a Randomized Comparison of the Proteomic Effects of Vicadrostat/Empagliflozin Versus Empagliflozin and Versus... | Baim Institute for Clinical Research | Phase 2 | Not yet recruiting | Heart Failure With Preserved Ejection Fraction (HFPEF) | 200 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07857772) |
| October 2, 2026 | NCT07856472 | AI-Powered Electrocardiography for Diagnosis and Prognostic Prediction in Cardiovascular Disease (AI-CVD): Multicenter Retrospective Study | Inha University Hospital | Observational | Recruiting | Cardiovascular Diseases, Coronary Artery Disease, Heart Failure, Atrial Fibrillation (AF), Ventricular Hypertrophy | 10,000 | South Korea | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07856472) |
| October 2, 2026 | NCT07856043 | \[11C\]PS13 PET Imaging of Neuroinflammation in Heart Failure With Reduced Ejection Fraction | Stony Brook University | Phase 1 | Not yet recruiting | Heart Failure With Reduced Ejection Fraction, Cognitive Impairment, Mild, Neuroinflammation, Vascular Contributions to... | 18 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07856043) |
| October 2, 2026 | NCT07855471 | Heart Failure Telemonitoring Across French Overseas Departments and Mainland France | Satelia | Observational | Completed | Heart Failure | 32,380 | France | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07855471) |
| October 1, 2026 | NCT07852221 | Patient Selection and Long-Term Outcomes of Pace & Ablate Strategy in Atrial Fibrillation | Insel Gruppe AG, University Hospital Bern | Observational | Recruiting | Atrial Fibrillation (AF), Cardiomyopathy, Secondary, Pacing-Induced Cardiomyopathy, Heart Failure | 2,600 | Poland, Switzerland, United Kingdom | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07852221) |
| September 30, 2026 | NCT07850726 | Deep Learning-Based Automated Pressure-Strain Loop Analysis | Norwegian University of Science and Technology | Not applicable | Not yet recruiting | Heart Failure | 25 | Norway | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07850726) |
| September 30, 2026 | NCT07849361 | Feasibility Study on the Implementation of a Program to Facilitate the Return Home of Patients With Heart Failure Following... | Sant'Innovation | Not applicable | Not yet recruiting | Heart Failure | 100 | France | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07849361) |
| September 29, 2026 | NCT07847983 | Heart Failure in Women: Epidemiological and Prognostic Insights | Carolina Ortiz Cortes | Observational | Recruiting | Heart Failure | 430 | Spain | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07847983) |
| September 29, 2026 | NCT07847112 | Soluble TREM-1 in Diabetes-Associated Cardiovascular Complications | Assiut University | Observational | Not yet recruiting | Type 2 Diabetes Mellitus, Cardiovascular Diseases, Coronary Artery Disease, Heart Failure, Arrhythmias, Arrhythmias... | 85 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07847112) |
| September 28, 2026 | NCT07845448 | A Cluster-Randomized Controlled Trial | Second Affiliated Hospital of Nanchang University | Not applicable | Not yet recruiting | Hypertension, Stroke, Cardiovascular, Coronary Heart Disease, Ischemic Heart Disease, Dyslipidaemia, Diabete Mellitus... | 14,400 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07845448) |
| September 28, 2026 | NCT07844434 | AI-Based Cardiac Analysis Using 12-Lead and 1-Lead ECG | Inha University Hospital | Observational | Recruiting | Heart Failure, Atrial Fibrillation (AF), Electrocardiogram | 300 | South Korea | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07844434) |
| September 25, 2026 | NCT07842874 | A Comparison of Left Bundle Branch Optimized Cardiac Resynchronization Therapy vs Left Bundle Branch Area Pacing Alone | PD Dr. Guram Imnadze | Not applicable | Not yet recruiting | Heart Failure, Left Bundle Branch Area Pacing, Cardiac Resynchronization Therapy, Conduction System Pacing | 124 | Germany | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07842874) |
| September 25, 2026 | NCT07841665 | AI-Based Personalized Self-Management for Patients With Heart Failure | Alexandria University | Not applicable | Not yet recruiting | Heart Failure | 150 | Egypt | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07841665) |
| September 23, 2026 | NCT07836764 | Validation of 1 Minute Sit-to Stand Test for Assessment of Breathlessness at Exertion in Individuals With Chronic Lung Disease | Jacob Sandberg | Observational | Not yet recruiting | COPD (Chronic Obstructive Pulmonary Disease), Asthma (Diagnosis), Interstitial Lung Disease (ILD) | 120 | Sweden | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07836764) |
| September 23, 2026 | NCT07835490 | Telemonitoring of HFrEF Patients | Medical University of Lodz | Not applicable | Active not recruiting | Heart Failure, Heart Failure With Reduced Ejection Fraction (HFrEF) | 60 | Poland | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07835490) |
| September 22, 2026 | NCT07833384 | The Effect of Providing Genetic Risk Information on Lifestyle Behaviors in African Americans | Pennington Biomedical Research Center | Early phase 1 | Completed | Diabetes, Hypercholesterolaemia, Hypertension, Obesity Type 2 Diabetes Mellitus, Obesity & Overweight, Heart Failure... | 60 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07833384) |
| September 21, 2026 | NCT07831538 | Digital Outreach for Heart Failure Adherence | Kaiser Permanente | Not applicable | Not yet recruiting | CHF - Congestive Heart Failure | 13,714 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07831538) |
| September 17, 2026 | NCT07824687 | Effect of Mindful Breathing in Patient With Heart Failure: | Ankara Medipol University | Not applicable | Completed | Heart Failure, Nursing Care, Symptom Management, Mindful Breathing Meditation | 64 | Turkey (Türkiye) | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07824687) |
| September 16, 2026 | NCT07821801 | Short-Term Outcomes of HFrEF Patients on Guideline-Directed Medical Therapy | Assiut University | Observational | Not yet recruiting | Heart Failure, Heart Failure, Systolic | 250 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07821801) |
| September 14, 2026 | NCT07818941 | 10 Degree C Static Storage in Heart Transplantation | John Trahanas | Not applicable | Not yet recruiting | Transplant, Failure, Heart, Heart Transplant, Heart Failure | 25 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07818941) |
| September 14, 2026 | NCT07817589 | Yoga Based Cardiac Rehabilitation in Heart Failure Failure | Centre for Chronic Disease Control, India | Not applicable | Recruiting | Heart Failure With Reduced Ejection Fraction, Heart Failure NYHA Class II, Heart Failure NYHA Class III | 3,500 | India | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07817589) |
| September 14, 2026 | NCT07817576 | Serial Biomarker Testing and Cardiovascular Risk Stratification (ACHILLES) | University Hospital Freiburg | Observational | Active not recruiting | Heart Failure, ASCVD, CKD | 110,000 | Germany | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07817576) |
| September 14, 2026 | NCT07817186 | Clinical Trial of a MEK Inhibitor for RASopathy-Associated Severe Infantile Hypertrophic Cardiomyopathy: Baby MERIT | Carelon Research | Phase 3 | Not yet recruiting | HCM, Noonan Syndrome and Other Rasopathy, Heart Failure (Pediatric) | 25 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07817186) |
| September 11, 2026 | NCT07816458 | Alert-HF: Early Detection and Intervention on Atrial Fibrillation in Heart Failure Patients | Medisch Spectrum Twente | Phase 4 | Not yet recruiting | Heart Failure | 258 | Netherlands | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07816458) |
| September 11, 2026 | NCT07815470 | Dancing as an Alternative to the Traditional Exercising in Older Adults With Cardiac Diseases | University College, London | Not applicable | Active not recruiting | Heart Failure and Preserved Ejection Fraction | 120 | Azerbaijan | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07815470) |
| September 11, 2026 | NCT07814612 | Clinical Efficacy and Safety of Left Bundle Branch Area Pacing Using Quantitative Guidance of Multimodal Data in the Treatment of Heart... | Second Affiliated Hospital of Nanchang University | Not applicable | Recruiting | Heart Failure, Left Bundle Branch Block, Non-ischemic Cardiomyopathy | 100 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07814612) |
| September 10, 2026 | NCT07814118 | Multimodal Physiologic State Intelligence Study | Truway Health, Inc. | Observational | Enrolling by invitation | Heart Failure, Cardiomyopathies, Pulmonary Hypertension, Myocarditis; Acute or Subacute, Myocarditis Due to Drug... | 25,000 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07814118) |
| September 9, 2026 | NCT07809516 | Pedal Pump Clinical Trial on Edema V2 | Hillcrest | Not applicable | Recruiting | Lower Extremity Edema, Lower Extremity Edema Chronic, CHF - Congestive Heart Failure, CHF Exacerbation, Chronic Venous... | 30 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07809516) |
| September 4, 2026 | NCT07805811 | Testing Heart Failure Resilience Intervention for Caregivers (HEROIC) in Advanced Heart Failure | Johns Hopkins University | Phase 2 | Not yet recruiting | Heart Failure, Caregiver | 500 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07805811) |
| September 4, 2026 | NCT07805213 | KV-PREDICT Diagnostic Device in Patients With Heart Failure | KardioVis S.r.l. | Not applicable | Not yet recruiting | Heart Failure | 120 | Italy | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07805213) |
| September 3, 2026 | NCT07801144 | Bioimpedance-Guided Diuretics and Cardiac Progression in Asymptomatic Heart Failure | Kayseri Training and Research Hospital | Observational | Completed | Heart Failure | 80 | Turkey (Türkiye) | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07801144) |
| September 1, 2026 | NCT07798856 | Effects of a Multidisciplinary Integrated Care Model on Care Outcomes in Patients With Heart Failure With Preserved Ejection Fraction | Chimei Medical Center | Not applicable | Not yet recruiting | Heart Failure With Preserved Ejection Fraction (HFpEF), Heart Failure | 200 | Taiwan | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07798856) |
| September 1, 2026 | NCT07798713 | Quality of Life After Transcatheter Aortic Valve Implantation | Aalborg University Hospital | Observational | Active not recruiting | Aortic Stenosis, Heart Failure, Angina Pectoris, TAVI(Transcatheter Aortic Valve Implantation) | 200 | Denmark | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07798713) |
| September 1, 2026 | NCT07798219 | Pilot Study of Endoscopic Sleeve Gastroplasty for Obese Patients With Heart Failure and Preserved Ejection Fraction | Cedars-Sinai Medical Center | Not applicable | Not yet recruiting | Obesity (BMI\>30), Heart Failure With Preserved Ejection Fraction (HFPEF) | 20 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07798219) |
| August 31, 2026 | NCT07795814 | A Study of EDG-15400 in Adults With Heart Failure With Preserved Ejection Fraction (EQUINOX-HFpEF) | Edgewise Therapeutics, Inc. | Phase 2 | Recruiting | Heart Failure With Preserved Ejection Fraction | 90 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07795814) |
| August 31, 2026 | NCT07795632 | Sound Heart Spiritual Combined With Dhikr for Patients With Heart Failure | Risqi Wahyu Susanti | Not applicable | Not yet recruiting | Heart Failure | 60 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07795632) |
| August 31, 2026 | NCT07794930 | Integrating Values Based Communication in Heart Failure Management | Abigail Latimer | Not applicable | Not yet recruiting | Heart Failure | 200 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07794930) |
| August 31, 2026 | NCT07793968 | Point of Care NT-proBNP Testing for Suspected New Heart Failure Acute Care | University of Stirling | Not applicable | Active not recruiting | Heart Failure | 252 | United Kingdom | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07793968) |
| August 25, 2026 | NCT07784712 | Right Ventricular Septal Biopsy to Detect Cardiac Amyloidosis | Geisinger Clinic | Observational | Not yet recruiting | ATTR-CM (Transthyretin Amyloid Cardiomyopathy), Heart Failure | 70 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07784712) |
| August 24, 2026 | NCT07781826 | Influence of Neurohormonal Blockade on Natriuresis in Heart Failure Patients | Wroclaw Medical University | Early phase 1 | Completed | Heart Failure | 80 | Poland | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07781826) |
| August 24, 2026 | NCT07781462 | Intravenous Infusion of Low Dose Ketamine Versus Dexmedetomedine for Delirium Treatment in Acute Heart Failure | Alexandria University | Phase 4 | Not yet recruiting | Delirium in Intensive Care Unit, Acute Heart Failure (AHF) | 150 | Egypt | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07781462) |
| August 20, 2026 | NCT07775976 | Cor360: Clinician-Facing Broad-Spectrum Cardiac Phenotyping and Risk Assessment Using COR® Wearable ECG to Inform Outcomes-Oriented Care... | Peerbridge Health, Inc | Observational | Enrolling by invitation | Cardiovascular Diseases, Cardiovascular Diseases Risk, Cardiac Conduction System Disease, Bundle/Fascicular... | 1,000 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07775976) |
| August 18, 2026 | NCT07771231 | Kosmos PLAX EF Pivotal Study | EchoNous Inc. | Observational | Active not recruiting | Heart, Heart Failure, Ejection Fraction, Left Ventricular Ejection Fraction, Left Ventricular Ejection Fraction Less... | 416 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07771231) |
| August 18, 2026 | NCT07770230 | RADIATE-HF - Efficacy and Safety of Cardiac Radiation in Advanced Heart Failure | Rennes University Hospital | Not applicable | Not yet recruiting | Heart Failure | 20 | France | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07770230) |
| August 14, 2026 | NCT07766135 | Liver and Coagulation Disorders in Cardiac Transthyretin Amyloidosis | University of Messina | Observational | Recruiting | Transthyretin (TTR) Amyloid Cardiomyopathy, Cardiac Amyloidosis, Cardiomyopathies, Wild-Type Transthyretin Cardiac... | 70 | Italy | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07766135) |
| August 14, 2026 | NCT07766109 | Discontinuation or Continuation of SGLT-2 Inhibitors Before Cardiac Surgery | University Hospital, Toulouse | Phase 4 | Not yet recruiting | Heart Failure, Cardiac Surgery | 434 | France | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07766109) |
| August 13, 2026 | NCT07763353 | Effects of Slow-paced Breathing on Heart Rate Variability in Patients With Heart Failure | Chung Shan Medical University | Not applicable | Not yet recruiting | Heart Failure | 27 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07763353) |
| August 13, 2026 | NCT07762560 | Routine Microaxial Heart Pump Support and Protocolized Pulmonary Artery Catheter Monitoring Versus Standard Care in Heart Attack-Related... | Leipzig Heart Science gGmbH | Not applicable | Recruiting | Cardiogenic Shock, Acute Myocardial Infarction (AMI), Heart Failure, Acute | 780 | Germany | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07762560) |
| August 12, 2026 | NCT07761117 | A Study to Investigate CV Outcomes With Elecoglipron Compared With Placebo in Adult Participants With HFpEF or HFmrEF | AstraZeneca | Phase 3 | Recruiting | Heart Failure With Preserved Ejection Fraction (HFpEF), Heart Failure With Mildly Reduced Ejection Fraction (HFmrEF) | 6,950 | Argentina, Australia, Austria, Brazil, Bulgaria, Canada, China, Czechia... | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07761117) |
| August 12, 2026 | NCT07760363 | Pedal Pump Clinical Trial on Edema V1 | David McVay | Not applicable | Recruiting | Lower Extremity Edema, Congestive Heart Failure(CHF), Chronic Venous Insufficiency (CVI), Kidney Disease | 60 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07760363) |
| August 12, 2026 | NCT07759700 | Bundle Branch Pacing to Preserve Ejection Fraction in Atrial Fibrillation Trial | Poitiers University Hospital | Not applicable | Recruiting | Permanent Atrial Fibrillation, Preserved Ejection Fraction | 642 | France | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07759700) |
| August 10, 2026 | NCT07756398 | Importance of Point-of-Care Ultrasound for Early Detection of Valvular and Cardiac Diseases (IMPROVE) | University of Texas Southwestern Medical Center | Not applicable | Not yet recruiting | Valvular Heart Disease Patients, Aortic Stenosis, Mitral Regurgitation, Left Ventricular Diastolic Dysfunction | 1,088 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07756398) |
| August 7, 2026 | NCT07753681 | Domestication and Implementation of the PEN-Plus Clinical Model in the Zambian Health System | Centre for Infectious Disease Research in Zambia | Observational | Recruiting | Cardiac Diseases, Sickle Cell Disease, Hypertension, Diabetes Mellitus, Heart Failure, Congenital Heart Disease... | 2,084 | Zambia | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07753681) |
| August 7, 2026 | NCT07753135 | Association of Heart Failure Aggravation and Device-based Sensor Parameters | Samsung Medical Center | Observational | Active not recruiting | Heart Failure, Cardiomyopathy | 500 | South Korea | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07753135) |
| August 7, 2026 | NCT07752706 | Breathing Exercises for Dyspnea and Anxiety in Heart Failure | Istanbul University - Cerrahpasa | Not applicable | Active not recruiting | Heart Failure, Breathing Exercises, Dyspnea, Anxiety | 112 | Turkey (Türkiye) | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07752706) |
| August 6, 2026 | NCT07750873 | A Trial of CRD-4730 in HFrEF | Cardurion Pharmaceuticals, Inc. | Phase 2 | Recruiting | Heart Failure With Reduced Ejection Fraction (HFrEF) | 525 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07750873) |
| August 6, 2026 | NCT07750262 | Mobile Health Intervention to Increase Activity in Heart Failure Study | University of Michigan | Not applicable | Recruiting | Heart Failure | 50 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07750262) |
| August 6, 2026 | NCT07749183 | A Photoplethysmography-Based Machine Learning Algorithm for Early Atrial Fibrillation Detection: A Prospective Validation Study | Seerlinq s. r. o. | Observational | Recruiting | Atrial Fibrillation (AF), Heart Failure | 200 | Slovakia | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07749183) |
| August 3, 2026 | NCT07743125 | Patient-Executed, Clinician-Confirmed Diuretic Titration in Pulmonary Artery Pressure-Guided Heart Failure (SURPASS-HF) | Medical College of Wisconsin | Not applicable | Completed | Heart Failure | 21 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07743125) |
| August 3, 2026 | NCT07741305 | Comparison of Three-dimensional and Two-dimensional Left Ventricle Strain With Speckle-tracking Echocardiography in Heart Failure With... | Istituti Clinici Scientifici Maugeri SpA | Observational | Recruiting | Heart Failure | 419 | Italy | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07741305) |
| July 31, 2026 | NCT07740044 | Medical Large Language Model-Assisted Diagnosis and Treatment in Primary Care Chronic Disease Management | Jiangsu Taizhou People's Hospital | Not applicable | Not yet recruiting | Coronary Artery Disease, Atrial Fibrillation (AF), Heart Failure, Stroke | 20 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07740044) |
| July 30, 2026 | NCT07737964 | ACetazolamide in Patients With Heart Failure, to Decrease Weight and relIEVE Symptoms. | University Hospital, Montpellier | Phase 3 | Not yet recruiting | Heart Failure | 366 | France | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07737964) |

## Sponsors posting most

| Sponsor | New trials | Latest |
| --- | --- | --- |
| Yonsei University | 8 | July 23, 2026 |
| Novo Nordisk A/S | 7 | June 18, 2026 |
| Jiangsu Taizhou People's Hospital | 6 | October 27, 2026 |
| National Taiwan University Hospital | 6 | June 18, 2026 |
| Brigham and Women's Hospital | 6 | March 25, 2026 |
| IRCCS Azienda Ospedaliero-Universitaria di Bologna | 5 | June 9, 2026 |
| University Medical Center Groningen | 5 | May 22, 2026 |
| Shanghai Zhongshan Hospital | 5 | April 15, 2026 |
| Yale University | 5 | February 10, 2026 |
| Stanford University | 4 | November 3, 2026 |
| University of Alberta | 4 | October 30, 2026 |
| Assistance Publique - Hôpitaux de Paris | 4 | October 28, 2026 |
| Abbott Medical Devices | 4 | October 16, 2026 |
| Washington University School of Medicine | 4 | October 5, 2026 |
| Satelia | 4 | October 2, 2026 |
| Assiut University | 4 | September 29, 2026 |
| AstraZeneca | 4 | August 12, 2026 |
| Mayo Clinic | 4 | July 28, 2026 |
| Riphah International University | 4 | June 23, 2026 |
| The Cleveland Clinic | 4 | June 16, 2026 |

## By phase

| Phase | New trials | Latest |
| --- | --- | --- |
| [Not applicable](https://specstream.ai/data/clinical-trials/phase/not-applicable) | 335 | November 4, 2026 |
| [Observational](https://specstream.ai/data/clinical-trials/phase/observational) | 284 | November 6, 2026 |
| [Phase 4](https://specstream.ai/data/clinical-trials/phase/phase-4) | 33 | November 9, 2026 |
| [Phase 2](https://specstream.ai/data/clinical-trials/phase/phase-2) | 32 | October 5, 2026 |
| [Phase 3](https://specstream.ai/data/clinical-trials/phase/phase-3) | 30 | November 6, 2026 |
| [Phase 1](https://specstream.ai/data/clinical-trials/phase/phase-1) | 21 | October 6, 2026 |
| [Early phase 1](https://specstream.ai/data/clinical-trials/phase/early-phase-1) | 7 | October 20, 2026 |
| [Phase 1/2](https://specstream.ai/data/clinical-trials/phase/phase-1-2) | 6 | June 24, 2026 |
| [Phase 2/3](https://specstream.ai/data/clinical-trials/phase/phase-2-3) | 2 | March 24, 2026 |

## By country

| Country | New trials | Latest |
| --- | --- | --- |
| [United States](https://specstream.ai/data/clinical-trials/country/united-states) | 172 | November 3, 2026 |
| [China](https://specstream.ai/data/clinical-trials/country/china) | 79 | November 3, 2026 |
| [Italy](https://specstream.ai/data/clinical-trials/country/italy) | 58 | November 6, 2026 |
| [France](https://specstream.ai/data/clinical-trials/country/france) | 58 | October 28, 2026 |
| [Germany](https://specstream.ai/data/clinical-trials/country/germany) | 53 | October 5, 2026 |
| [Spain](https://specstream.ai/data/clinical-trials/country/spain) | 51 | September 29, 2026 |
| [United Kingdom](https://specstream.ai/data/clinical-trials/country/united-kingdom) | 43 | October 19, 2026 |
| [Turkey (Türkiye)](https://specstream.ai/data/clinical-trials/country/turkey-t-rkiye) | 39 | November 4, 2026 |
| [South Korea](https://specstream.ai/data/clinical-trials/country/south-korea) | 33 | October 6, 2026 |
| [Netherlands](https://specstream.ai/data/clinical-trials/country/netherlands) | 29 | September 11, 2026 |
| [Poland](https://specstream.ai/data/clinical-trials/country/poland) | 28 | October 1, 2026 |
| [Sweden](https://specstream.ai/data/clinical-trials/country/sweden) | 25 | September 23, 2026 |
| [Brazil](https://specstream.ai/data/clinical-trials/country/brazil) | 24 | August 12, 2026 |
| [Canada](https://specstream.ai/data/clinical-trials/country/canada) | 24 | August 12, 2026 |
| [Taiwan](https://specstream.ai/data/clinical-trials/country/taiwan) | 23 | October 22, 2026 |
| [Denmark](https://specstream.ai/data/clinical-trials/country/denmark) | 19 | October 21, 2026 |
| [Czechia](https://specstream.ai/data/clinical-trials/country/czechia) | 17 | August 12, 2026 |
| [Portugal](https://specstream.ai/data/clinical-trials/country/portugal) | 15 | November 9, 2026 |
| [Switzerland](https://specstream.ai/data/clinical-trials/country/switzerland) | 13 | October 1, 2026 |
| [Bulgaria](https://specstream.ai/data/clinical-trials/country/bulgaria) | 12 | October 13, 2026 |
| [Egypt](https://specstream.ai/data/clinical-trials/country/egypt) | 12 | September 25, 2026 |
| [Austria](https://specstream.ai/data/clinical-trials/country/austria) | 12 | August 12, 2026 |
| [Hungary](https://specstream.ai/data/clinical-trials/country/hungary) | 11 | August 12, 2026 |
| [Japan](https://specstream.ai/data/clinical-trials/country/japan) | 11 | August 12, 2026 |
| [Belgium](https://specstream.ai/data/clinical-trials/country/belgium) | 11 | April 29, 2026 |

## Where the register publishes

- [ClinicalTrials.gov](https://clinicaltrials.gov/)
- [ClinicalTrials.gov API](https://clinicaltrials.gov/data-api/api)

Source: [ClinicalTrials.gov API v2 (U.S. National Library of Medicine)](https://clinicaltrials.gov/data-api/api). U.S. government data; ClinicalTrials.gov terms of use. Studies are as their sponsors registered them on ClinicalTrials.gov, read through its API. Condition groups are the MeSH terms ClinicalTrials.gov assigns to each study's conditions; a study with several is in several groups. Sponsor class is the register's class of the lead sponsor. The central contact is in the full list only as the record prints it.

Free to reuse with credit to SpecStream under [CC BY 4.0](https://creativecommons.org/licenses/by/4.0/).