# Heart Defects, Congenital trials: 162 new since Nov 2024

Updated November 9, 2026.

162 clinical studies in Heart Defects, Congenital were first posted on ClinicalTrials.gov from November 13, 2024 to November 9, 2026; 8 have an industry sponsor and 118 are recruiting or about to. The newest, NCT07923942, was posted on November 9, 2026: Cerebral Monitoring and Postoperative Delirium in Pediatric Cardiac Surgery (Universitas Indonesia).

## The full list

New Heart Defects, Congenital clinical trials: 162 rows for $8.10, first posted on ClinicalTrials.gov from November 12, 2024 to November 9, 2026. Columns: NCT ID, Title, Sponsor, Sponsor class, Phase, Status, Conditions, Condition groups (MeSH), Interventions, Start date, First posted, Enrollment, Enrollment type, Location countries, Central contact, Contact phone, Contact email, Last update posted, Read on, Source. The new rows each week by email, about 9 rows a month: $19 a month. Pay by card with no account. Prices exclude VAT. CSV and Excel files with the columns this page does not show (central contact, contact phone, contact email, sponsor class, condition groups (MeSH), interventions and 5 more), which open on your screen as soon as the payment clears and come by email. The rows on this page are a sample.

Buy: https://specstream.ai/data/clinical-trials/condition/heart-defects-congenital

SpecStream is the live web data engine for teams and agents. It reads every new study on ClinicalTrials.gov each morning, and this page is that reading. Ask for the conditions, phases or countries you follow and each new trial arrives in your sheet, CRM, Slack or agent with the sponsor, the sites and the listed contact.

- New trials: 162
- Industry sponsored: 8
- Recruiting or not yet: 118
- Latest posted: November 9, 2026

## Newest trials

The newest 100 of 162, each linked to its record. The full list holds every one with the sponsor class, interventions, start date and the central contact as the record prints it.

| First posted | NCT ID | Title | Sponsor | Phase | Status | Conditions | Enrollment | Countries | Source |
| --- | --- | --- | --- | --- | --- | --- | --- | --- | --- |
| November 9, 2026 | NCT07923942 | Cerebral Monitoring and Postoperative Delirium in Pediatric Cardiac Surgery | Universitas Indonesia | Observational | Completed | Congenital Heart Disease, Pediatric Open Heart Surgery, Delirium - Postoperative, Transcranial Doppler Ultrasound, Near... | 42 | Indonesia | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07923942) |
| October 28, 2026 | NCT07901998 | Optimization of Two-Indicator Screening Protocol for Neonatal Congenital Heart Disease at High Altitude | Children's Hospital of Fudan University | Observational | Not yet recruiting | Neonatal Congenital Heart Disease | 6,300 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07901998) |
| October 27, 2026 | NCT07898384 | Optimizing Care Transitions in CHD | The Hospital for Sick Children | Not applicable | Not yet recruiting | Congenital Heart Disease (CHD), Mentorship, Transition of Care, Peer Support, Peer Support and Chronic Disease... | 110 | Canada | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07898384) |
| October 20, 2026 | NCT07884318 | Long-term Safety Study Following to JRM-001 Treatment in Pediatric Patients With Congenital Heart Disease | Metcela Inc. | Observational | Recruiting | Single Ventricle, Hypoplastic Left Heart Syndrome (HLHS) | 40 | Japan | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07884318) |
| October 8, 2026 | NCT07866924 | Echocardiographic Assessment of Valvular Dysfunction in Children With CHD | Assiut University | Observational | Not yet recruiting | Congenital Heart Disease, Valvular Heart Disease | 100 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07866924) |
| October 8, 2026 | NCT07866911 | RVOT Stenting Versus Surgical RV-PA Conduit in Cyanotic Adults | Assiut University | Observational | Not yet recruiting | Cyanotic Congenital Heart Disease, Right Ventricular Outflow Tract Obstruction | 30 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07866911) |
| October 8, 2026 | NCT07866573 | UltraTrac for Cardiac Output Monitoring in Congenital Heart Disease | University of Minnesota | Not applicable | Not yet recruiting | Congenital Heart Disease, Cardiac Output, Hemodynamic Monitoring, Pediatric Heart Disease | 70 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07866573) |
| October 7, 2026 | NCT07864129 | Volution of Pulmonary Artery Dimensions in Tetralogy of Fallot | University Hospital, Strasbourg, France | Observational | Recruiting | Tetralogy of Fallot (TOF), Congenital Heart Defects | 400 | France | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07864129) |
| October 2, 2026 | NCT07854171 | The Effect of Telerehabilitation Exercises in Children With Congenital Heart Disease | Izmir Democracy University | Not applicable | Not yet recruiting | Congenital Heart Disease, Telerehabilitation, Functional Inspiratory Muscle Training | 32 | Turkey (Türkiye) | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07854171) |
| October 2, 2026 | NCT07854145 | Starry-Sky Projection and Maternal Voice for Sleep After Pediatric Cardiac Surgery | Shanghai Jiao Tong University School of Medicine | Not applicable | Not yet recruiting | Congenital Heart Disease (CHD), Postoperative Sleep | 172 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07854145) |
| September 28, 2026 | NCT07844213 | Early Postoperative Triple Targeted Therapy in Patients With CHD-PAH in the "Grey Zone" | China National Center for Cardiovascular Diseases | Not applicable | Completed | Congenital Heart Disease, Pulmonary Hypertension | 30 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07844213) |
| September 24, 2026 | NCT07839273 | Morphine Versus Fentanyl for Myocardial Protection in Acyanotic Children Undergoing Congenital Open-Heart Surgery | Baskent University | Phase 4 | Completed | Heart Defects, Congenital, Myocardial Reperfusion Injury | 66 | Turkey (Türkiye) | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07839273) |
| September 23, 2026 | NCT07837024 | TORCH-LATAM-003: Regional Advanced-Therapy Pathways for Congenital Heart Disease | CardioVision International Tech, S.A.S. de C.V. | Not applicable | Not yet recruiting | Congenital Heart Disease, Advanced Heart Failure, Respiratory Failure, Heart Transplantation, Lung Transplantation... | 360 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07837024) |
| September 22, 2026 | NCT07832851 | Fetal Cardiac Anomalies at Anomaly Scan: Detection and Pregnancy Outcomes - Assiut 2026 | Assiut University | Observational | Not yet recruiting | Congenital Heart Defect, Heart Defects, Congenital | 200 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07832851) |
| September 21, 2026 | NCT07830251 | AI-Assisted Versus Independent Heart Sound Screening for Congenital Heart Disease in Children | Kun Sun | Not applicable | Not yet recruiting | Congenital Heart Disease (CHD), Artifical Intelligence, Screening, Cardiac Auscultation, Primary Care Physician | 10,000 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07830251) |
| September 15, 2026 | NCT07820163 | Perinatal Cardiology: Bridging Obstetric and Neonatal Care in CHD | Assiut University | Observational | Not yet recruiting | Congenital Heart Disease, Fetal Heart Disorder, Neonatal Disease, Fetal Disease | 115 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07820163) |
| September 10, 2026 | NCT07812818 | MAGiC - Congenital Heart DIsease | Stereotaxis | Observational | Not yet recruiting | Supraventricular Tachycardia (SVT), Congenital Heart Disease (CHD) | 40 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07812818) |
| September 2, 2026 | NCT07799272 | TORCH-LATAM: A Regional Pathway to Improve Transplant Evaluation for Congenital Heart Disease | CardioVision International Tech, S.A.S. de C.V. | Not applicable | Not yet recruiting | Congenital Heart Disease | 600 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07799272) |
| September 2, 2026 | NCT07799259 | Autologous Thymus Transplant in Children With Congenital Heart Disease: A Pilot Study | Children's Hospital Medical Center, Cincinnati | Not applicable | Not yet recruiting | Congenital Heart Disease (CHD) | 10 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07799259) |
| August 27, 2026 | NCT07791069 | International Multicenter Outcomes of Transcatheter Pulmonary Flow Restrictors in Congenital and Acquired Heart Disease | Fondation Hôpital Saint-Joseph | Observational | Enrolling by invitation | Congenital Heart Disease | 150 | France, Germany, Serbia, United Arab Emirates, United Kingdom | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07791069) |
| August 25, 2026 | NCT07785141 | Spectroscopic Assessment of Myocardial Oxygenation Changes in Pediatric Heart Surgery | Spectrocor | Observational | Recruiting | Myocardial Ischemia, Heart Defects, Congenital, Reperfusion Injury, Myocardial | 30 | Finland | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07785141) |
| August 18, 2026 | NCT07771491 | Localized Evidence of Cytokine Adsorption Therapy During Pediatric Cardiac Surgery: A Single Center Randomized Controlled Trial (LEAT) | Norfaniza Zabidi | Not applicable | Not yet recruiting | Congenital Heart Disease, Open Heart Surgery, Cardiopulmonary Bypass, Endocarditis Acute and Subacute, Cyanotic Heart... | 120 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07771491) |
| August 18, 2026 | NCT07771023 | Effects of Exercise in Patients With Repaired Coarctation of the Aorta | University Medical Centre Ljubljana | Not applicable | Enrolling by invitation | Coarctation of the Aorta, Coarctation of Aorta | 45 | Slovenia | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07771023) |
| August 14, 2026 | NCT07764510 | Heart2Heart for Teens With CHD | Kristen Fox | Not applicable | Enrolling by invitation | Congenital Heart Disease, Health Behavior | 90 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07764510) |
| August 7, 2026 | NCT07753681 | Domestication and Implementation of the PEN-Plus Clinical Model in the Zambian Health System | Centre for Infectious Disease Research in Zambia | Observational | Recruiting | Cardiac Diseases, Sickle Cell Disease, Hypertension, Diabetes Mellitus, Heart Failure, Congenital Heart Disease... | 2,084 | Zambia | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07753681) |
| August 3, 2026 | NCT07742046 | Feasibility of Non-invasive Hemodynamic Assessment by 5D Flow in Congenital Heart Disease | Tobias Rutz | Not applicable | Enrolling by invitation | Pulmonary Hypertension, Right Ventricular Outflow Tract Dysfunction, Fontan Circulation | 130 | Switzerland | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07742046) |
| August 3, 2026 | NCT07741097 | Prediction Model of Spontaneous Closure of Congenital Perimembranous Ventricular Septal Defects | Xinhua Hospital, Shanghai Jiao Tong University School of Medicine | Observational | Withdrawn | Ventricular Septal Defects | 0 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07741097) |
| August 3, 2026 | NCT07740915 | Comparison of Erector Spinae Plane Block and Modified Pectoral Fascial Plane Block for Postoperative Analgesia in Pediatric Cardiac Surgery | Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital | Not applicable | Completed | Congenital Heart Disease, Postoperative Pain After Cardiac Surgery Via Median Sternotomy, Anesthesia | 50 | Turkey (Türkiye) | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07740915) |
| July 28, 2026 | NCT07732244 | Evaluating a Wireless NIRS Device in the Neonatal Intensive Care Unit | McGill University Health Centre/Research Institute of the McGill University Health Centre | Not applicable | Recruiting | Hypoxic-Ischemic Encephalopathy, Congenital Heart Disease, Stroke Hemorrhagic, Aneurysm Cerebral | 20 | Canada | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07732244) |
| July 21, 2026 | NCT07716488 | Screening for Disorders of Lipid Metabolism and Familial Hyperlipidemia in Children and Adolescents With Increased Cardiovascular Risk Due... | Alexandra Miriam Kiess | Not applicable | Recruiting | Lipid Metabolism Disorders, Lipid Metabolism, Inborn Errors, Congenital Heart Disease, Inflammatory Bowel Disease... | 600 | Germany | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07716488) |
| July 15, 2026 | NCT07706140 | Observational Data Collection for Blood Hemoglobin Algorithm Validation in Pediatrics | Boston Children's Hospital | Observational | Not yet recruiting | Hemoglobin, Cerebral Oxygenation, Congenital Heart Disease | 100 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07706140) |
| July 14, 2026 | NCT07700459 | Exercise Prehabilitation in Congenital Heart Disease | Liverpool Heart and Chest Hospital NHS Foundation Trust | Not applicable | Recruiting | Congenital Heart Disease, Cardiac Surgery | 32 | United Kingdom | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07700459) |
| July 13, 2026 | NCT07697755 | Interoceptive Intervention for Congenital Heart Disease | University of Glasgow | Not applicable | Not yet recruiting | Interoception, Congenital Heart Disease | 32 | United Kingdom | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07697755) |
| July 9, 2026 | NCT07692958 | Executive Function Intervention for Children With Complex Congenital Heart Disease | Bea Latal | Not applicable | Recruiting | Heart Defect, Congenital, Executive Dysfunction | 160 | Switzerland | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07692958) |
| July 7, 2026 | NCT07686341 | PRecision Integrated Saturation Monitor | Le Bonheur Children's Hospital | Observational | Recruiting | CHD - Congenital Heart Disease, Single Ventricle Heart Disease | 100 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07686341) |
| June 23, 2026 | NCT07663799 | Wearable Assessment of Thoracic, Cardiac Health and Exercise Performance Trial Prospective | The University of Hong Kong | Observational | Not yet recruiting | Congenital Heart Disease, Pulmonary Hypertension, Heart Failure, Coronary Heart Disease (CHD), Apple Watch | 20 | Hong Kong | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07663799) |
| June 23, 2026 | NCT07662343 | Early Warning of Structural Complications in Perimembranous VSD | Xinhua Hospital, Shanghai Jiao Tong University School of Medicine | Observational | Active not recruiting | Congenital Heart Disease (CHD), Ventricular Septal Defects (VSD) | 11,683 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07662343) |
| June 11, 2026 | NCT07643168 | The Effect of Therapeutic Play on Preoperative Anxiety in Hospitalized Children With Congenital Heart Disease | First Affiliated Hospital of Kunming Medical University | Not applicable | Not yet recruiting | Congenital Heart Disease (CHD) | 204 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07643168) |
| May 29, 2026 | NCT07613398 | An International Multicenter, Multivendor Evaluation of the Free-Running Framework for Cardiac Function | Matthias Stuber | Observational | Not yet recruiting | Congenital Heart Diseases, Cardiac Diseases | 300 | Australia, Colombia, Germany, Italy, Japan, Netherlands, Singapore, South... | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07613398) |
| May 18, 2026 | NCT07593118 | Exergame-Based Physical Activity Promotion for Children and Adolescents With Congenital Heart Disease | The Children's Hospital of Zhejiang University School of Medicine | Not applicable | Not yet recruiting | Congenital Heart Disease, Physical Inactivity | 13 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07593118) |
| May 13, 2026 | NCT07585175 | Transition and Transfer of Congenital Heart Disease Care From Pediatrics to Adulthood | Ottawa Heart Institute Research Corporation | Observational | Recruiting | Congenital Heart Disease (CHD) | 200 | Canada | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07585175) |
| May 13, 2026 | NCT07583680 | A Clinical Study Used to Estimate Central Venous Pressure Non-invasively Using Occlusion Pressure | Le Bonheur Children's Hospital | Observational | Not yet recruiting | Pediatric Congestive Heart Failure, Congestive Heart Failure | 30 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07583680) |
| May 13, 2026 | NCT07582861 | Prenatally-initiated Psychological Intervention for Mothers of Infants With Congenital Heart Disease (CHD) | Carelon Research | Not applicable | Recruiting | Congenital Heart Disease (CHD) | 210 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07582861) |
| May 13, 2026 | NCT07582848 | BOND: Direct Breastfeeding to Enhance Maternal and Infant Health in Congenital Heart Disease | Carelon Research | Not applicable | Recruiting | Congenital Heart Disease (CHD) | 266 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07582848) |
| May 8, 2026 | NCT07575451 | Empowering Families in Pediatric Cardiovascular Surgery: A RAM-Based Approach | Cukurova University | Not applicable | Not yet recruiting | Congenital Heart Disease, Postoperative Care, Child Development, Roy Adaptation Model-based Nursing Empowerment Program | 80 | Turkey (Türkiye) | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07575451) |
| May 8, 2026 | NCT07574931 | Outcome of Ablation of Tachyarrhythmias in Patients With Congenital Heart Diseases | Fayoum University | Observational | Completed | Congenital Heart Disease, Arrhythmia, Ablation of Arrhythmias | 40 | Egypt | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07574931) |
| May 8, 2026 | NCT07574463 | Adaptive Digital Exercise Rehabilitation for Children After CHD Surgery | The Children's Hospital of Zhejiang University School of Medicine | Not applicable | Not yet recruiting | Congenital Heart Disease (CHD), Congenital Heart Disease in Children | 130 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07574463) |
| May 4, 2026 | NCT07564882 | The Effect of Music and Musical Mobile Interventions on Pain and Physiological Parameters | Baskent University | Not applicable | Recruiting | Congenital Heart Disease (CHD), Chest Tube Removal | 54 | Turkey (Türkiye) | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07564882) |
| April 30, 2026 | NCT07559253 | Implementation of an Accessible Healthcare Model (ACHD STRONG): Comparing Nurse and Physician Lead Healthcare Transition Education in a... | University of Wisconsin, Madison | Not applicable | Recruiting | Congenital Heart Disease | 450 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07559253) |
| April 29, 2026 | NCT07556185 | MedlyPeds Feasibility Study | The Hospital for Sick Children | Not applicable | Recruiting | Pediatric Heart Failure, Congenital Heart Disease (CHD), Acquired Heart Disease, Pulmonary Hypertension, Post Cardiac... | 30 | Canada | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07556185) |
| April 27, 2026 | NCT07552688 | "Effects of High-Calorie Diets VS High-Calorie Formulas on Weight Gain in Children With Congenital Heart Disease " | Aryan Najmadin Nasradin | Not applicable | Not yet recruiting | Weight Gain, Body Mass Index, Pediatric Nutrition, Congenital Heart Disease, Undernutrition | 75 | Iraq | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07552688) |
| April 22, 2026 | NCT07546227 | HIIT Versus Moderate Continuous Training in ACHD | University of Alberta | Not applicable | Completed | Adult Congenital Heart Disease | 47 | Canada | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07546227) |
| April 17, 2026 | NCT07535203 | Fontan Outcomes in Oligemia vs Plethora in Univentricular CHD | Sisca Natalia Siagian | Observational | Recruiting | Congenital Heart Disease (CHD), Univentricular Heart | 52 | Indonesia | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07535203) |
| April 13, 2026 | NCT07524998 | A Chinese Multicenter Study on Surgical Techniques and Outcomes Across the Lifespan in Congenital Heart Disease | China National Center for Cardiovascular Diseases | Observational | Recruiting | Congenital Heart Disease, Complex Congenital Heart Disease, Surgery (Cardiac), Perioperative Care, Quality Control... | 3,000 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07524998) |
| April 13, 2026 | NCT07521488 | LLM-Based Intelligent Health Management Assistant in Life-Cycle Health Management of Cardiac Surgery Patients | Beijing Anzhen Hospital | Not applicable | Not yet recruiting | Coronary Artery Bypass Grafting, Heart Valve Disease, Aortic Aneurysm, Aortic Dissection, Congenital Heart Disease... | 500 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07521488) |
| April 9, 2026 | NCT07520149 | Chest X-Rays for Early Detection of Congenital Heart Disease in Newborns | Assiut University | Observational | Not yet recruiting | Congenital Heart Disease, Chest X-ray for Clinical Evaluation, Neonates | 60 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07520149) |
| March 31, 2026 | NCT07503158 | Prospective Evaluation of Cardiac Point-of-Care Ultrasound (POCUS) Performed by PEM Fellows and Artificial Intelligence on Children With... | Nicklaus Children's Hospital f/k/a Miami Children's Hospital | Observational | Not yet recruiting | Cardiac Anomalies | 200 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07503158) |
| March 30, 2026 | NCT07499154 | Perioperative Lidocaine for Lung Protection in Infants Undergoing Cardiac Surgery | The Children's Hospital of Zhejiang University School of Medicine | Phase 4 | Not yet recruiting | Congenital Heart Disease, Postoperative Pulmonary Complications, Acute Lung Injury | 320 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07499154) |
| March 27, 2026 | NCT07498803 | Sota-ES - Sotatercept in Patients With Congenital Heart Disease and Eisenmenger´s Syndrome | Philipps University Marburg | Phase 2 | Not yet recruiting | Congenital Heart Disease (CHD), Eisenmenger Syndrome, PAH | 40 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07498803) |
| March 20, 2026 | NCT07486167 | Influence of Lung Volume Optimization Maneuver on Cardiac Output and Lung Compliance in Ventilated Children With Congenital Heart Disease... | Charite University, Berlin, Germany | Phase 1/2 | Not yet recruiting | Congenital Heart Disease, Cardiopulmonary Bypass, Mechanical Ventilation, Peep Titration in Lung Protective... | 80 | Germany | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07486167) |
| March 19, 2026 | NCT07482943 | The Effect of Dapagliflozin on Exercise and Cardiac Functional Status of Patients After Fontan Procedure | The University of Hong Kong | Phase 4 | Recruiting | Fontan, Heart Failure, Dapagliflozin, Cardiovascular Diseases, Sodium-GLucose coTransporter-2 Inhibitors | 30 | Hong Kong | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07482943) |
| March 19, 2026 | NCT07481565 | Speech Therapy Online Approach for Children With Congenital Heart Desease in Pre and Post Surgical Period | Instituto de Cardiologia do Rio Grande do Sul | Not applicable | Completed | Deglutition Disorders in Children, Congenital Heart Disease | 20 | Brazil | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07481565) |
| March 18, 2026 | NCT07479654 | AI-Enabled Frailty Risk Prediction in Adult Congenital Heart Disease | Mackay Memorial Hospital | Not applicable | Not yet recruiting | Adult Congenital Heart Disease, Symptom Clusters, Frailty, Risk Prediction Model, Artificial Intelligence-Based Voice... | 410 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07479654) |
| March 17, 2026 | NCT07477197 | Heart Institute Biobank & Registry for Adult Congenital Heart Disease and Related Disorders | Children's Hospital Medical Center, Cincinnati | Observational | Recruiting | Adult Congenital Heart Disease, Pulmonary Hypertension, Connective Tissue Disease, Other Cardiovascular Conditions | 5,000 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07477197) |
| March 12, 2026 | NCT07466745 | Autus Valve Continued Access Study (CAS) | Edwards Lifesciences | Not applicable | Active not recruiting | Congenital Heart Disease | 4 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07466745) |
| February 27, 2026 | NCT07437261 | Neuropsychomotor Development From Ages 6 to 18 in Children With Early Surgically Treated Congenital Heart Disease | University Hospital, Toulouse | Observational | Completed | Congenital Cardiomyopathy | 155 | France | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07437261) |
| February 20, 2026 | NCT07425132 | Non-Invasive Electrocardiographic Imaging for Personalized Arrhythmia Care in Congenital Heart Disease | Fundacion para la Innovacion en Biomedicina (FIBMED) | Observational | Recruiting | Congenital Heart Disease | 15 | Spain | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07425132) |
| February 20, 2026 | NCT07424976 | Early Detection of Brain Injury After Congenital Heart Surgery in Infants | University Medical Centre Ljubljana | Observational | Enrolling by invitation | Congenital Heart Disease (CHD), Hypoxic Encephalopathy | 30 | Slovenia | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07424976) |
| February 19, 2026 | NCT07420660 | Muscle Function in Patients With Single-chamber Heart | Karolinska Institutet | Observational | Completed | Fontan Circulation | 34 | Sweden | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07420660) |
| February 17, 2026 | NCT07414251 | Evaluation of Preoperative Preparation in Children Undergoing Cardiac Surgery or Catheterization | Charite University, Berlin, Germany | Observational | Completed | Congenital Heart Disease in Children | 200 | Germany | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07414251) |
| February 12, 2026 | NCT07405333 | Effect of Coughing Exercises Versus Incentive Spirometry on Respiratory Function and Recovery in Children After Cardiac Surgery. | University of Baghdad | Not applicable | Recruiting | Congenital Heart Disease (CHD), Postoperative Respiratory Dysfunction, Postoperative Recovery After Cardiac Surgery | 99 | Iraq | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07405333) |
| February 4, 2026 | NCT07385209 | Design and Application of a Home Care WeChat Mini-Program for Children After Congenital Heart Disease Surgery | ruijie YangLan | Not applicable | Not yet recruiting | Congenital Heart Disease | 210 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07385209) |
| January 29, 2026 | NCT07376785 | Can Smartphones Listen to Your Heart? A Performance Study on Detecting Inborn Heart Diseases in Your Heart Sounds | The University of Hong Kong | Observational | Enrolling by invitation | Congenital Heart Disease (CHD) | 220 | Hong Kong | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07376785) |
| January 29, 2026 | NCT07375602 | A Multimodal AI Prediction Model for Complications After Transcatheter Closure of Perimembranous VSD in Children | Xinhua Hospital, Shanghai Jiao Tong University School of Medicine | Observational | Recruiting | Congenital Heart Disease (CHD), Ventricular Septal Defects (VSD), Cardiac Catheterization, Postoperative Complications | 5,249 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07375602) |
| January 28, 2026 | NCT07373873 | Growth in Infants With Congenital Heart Disease at AUCH | Assiut University | Observational | Not yet recruiting | Congenital Heart Disease (CHD) | 72 | Egypt | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07373873) |
| January 26, 2026 | NCT07365670 | Comparison of the Best Method for Measuring Anti-Xa Activity in Children Receiving Unfractionated Heparin in Cardiac Intensive Care... | Centre Hospitalier Universitaire de la Réunion | Not applicable | Not yet recruiting | Congenital Heart Disease, Unfractionated Heparin, Anti Xa Activity | 22 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07365670) |
| January 23, 2026 | NCT07361523 | Using Near-Infrared Spectroscopy Devices to Assess Myocardial and Visceral Perfusion During Complex Congenital Cardiac Surgery | Boston Children's Hospital | Observational | Not yet recruiting | Congenital Heart Disease | 50 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07361523) |
| January 21, 2026 | NCT07354880 | Effect of Tirzepatide on Cardiovascular and Metabolic Parameters in Obese Adult Patients With Congenital Heart Disease | University Medical Centre Ljubljana | Phase 4 | Not yet recruiting | Obesity & Overweight, Adult Congenital Heart Disease | 30 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07354880) |
| January 8, 2026 | NCT07326384 | Assessment of Psychiatric Problems in Pre- and Post-Intervention in Patients With CHD | Assiut University | Observational | Not yet recruiting | Congenital Heart Disease | 60 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07326384) |
| January 8, 2026 | NCT07326228 | Effect of Exercises on Ventilatory Function in Adult With TOF | Cairo University | Not applicable | Not yet recruiting | Tetralogy of Fallot (TOF), Adults With Repaired Tetralogy of Fallot | 60 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07326228) |
| January 7, 2026 | NCT07323979 | The Effects of Different Prone Positioning Angles on Cardiopulmonary Function in Children After Congenital Heart Disease Surgery: A... | Guangdong Provincial People's Hospital | Not applicable | Completed | CHD, Heart Defects, Congenital, Hypoxia, Respiratory Insufficiency, Postoperative Complications | 102 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07323979) |
| January 6, 2026 | NCT07319858 | The Effect of Using Multifunctional Baby Carrier With Heart Surgery | Istanbul University - Cerrahpasa | Not applicable | Not yet recruiting | Congenital Heart Surgery | 52 | Turkey (Türkiye) | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07319858) |
| December 23, 2025 | NCT07300358 | Study on the Safety and Effectiveness of a Biodegradable Patent Foramen Ovale Occluder System | Shanghai Lingsi Medical Technology Co., Ltd. | Not applicable | Not yet recruiting | Cardiovascular Diseases, Cardiovascular Abnormality, Heart Defects, Congenital, Heart Septal Defects, Heart Septal... | 258 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07300358) |
| December 23, 2025 | NCT07299721 | Brain Ultrafast Ultrasound Imaging | University Hospital, Bordeaux | Observational | Not yet recruiting | CHD - Congenital Heart Disease | 300 | France | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07299721) |
| November 28, 2025 | NCT07255144 | Ultrafast Ultrasound Imaging in Pediatric Cardiology | University Hospital, Bordeaux | Observational | Recruiting | CHD - Congenital Heart Disease | 300 | France | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07255144) |
| November 25, 2025 | NCT07249138 | Impact of Congenital Heart Disease on the Prognosis of Childhood Hematological Neoplasms: A Multicenter Cohort Study | Children's Hospital of Fudan University | Observational | Completed | Congenital Heart Disease (CHD), Hematologic Malignancy | 800 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07249138) |
| November 25, 2025 | NCT07247604 | Congenital Heart Diseases and Developmental Assessment in Cholestatic Infants Under Two Years | Assiut University | Observational | Not yet recruiting | Cholestasis, Congenital Heart Disease | 106 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07247604) |
| October 2, 2025 | NCT07204509 | Chromosomal Abnormalities in Patients With Congenital Heart Disease at Assiut University Children's Hospital | Assiut University | Observational | Not yet recruiting | Congenital Heart Disease (CHD), Chromosomal Abnormalities | 138 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07204509) |
| September 26, 2025 | NCT07193719 | Influence of Personalized Lung Volume Optimization Maneuver on Lung Function and Cardiac Performance in Children | Charite University, Berlin, Germany | Phase 1/2 | Recruiting | Congenital Heart Disease, Cardiopulmonary Bypass, Cardiac Surgery, Mechanical Ventilation, Positive End-expiratory... | 80 | Germany | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07193719) |
| August 27, 2025 | NCT07144501 | Prevalence of Liver Dysfunction in Pediatric Patients With Congenital Heart Disease at Assiut. | Assiut University | Not applicable | Not yet recruiting | Congenital Heart Disease, Liver Dysfunction | 40 | Egypt | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07144501) |
| August 20, 2025 | NCT07132593 | A Retrospective, Observational, and Descriptive Study of Pediatric Cardiac Fibroma | China National Center for Cardiovascular Diseases | Observational | Completed | Cardiac Tumor | 17 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07132593) |
| August 12, 2025 | NCT07118124 | Pediatric Adhesion and New Dermal Approach Study | iRhythm Technologies, Inc. | Not applicable | Completed | Syncope, Pediatric, Congenital Athymia, Congenital Heart Disease, Arrhythmia, Arrhythmia in Children | 36 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07118124) |
| August 11, 2025 | NCT07115589 | Home-based Cardiovascular Rehabilitation in Young Patients With Congenital Heart Disease: the "Muscle Your Heart" Program | University Hospital, Bordeaux | Not applicable | Not yet recruiting | CHD - Congenital Heart Disease | 21 | France | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07115589) |
| August 11, 2025 | NCT07115108 | Effectiveness of High-Energy Density Enteral Nutrition for Enhancing Physical Growth and Cognitive Brain Development in Infants With... | Children's Hospital of Fudan University | Not applicable | Recruiting | Congenital Heart Disease, Enteral Nutrition, Pediatrics | 160 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07115108) |
| August 11, 2025 | NCT07114718 | Starlight Cardiovascular Lifeline Ductus Arteriosus Stent IDE Study | Starlight Cardiovascular Inc | Not applicable | Recruiting | Congenital Heart Disease, Congenital Heart Disease (CHD) | 45 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07114718) |
| August 8, 2025 | NCT07112794 | Calprotectin and Gut Disease Study | Great Ormond Street Hospital for Children NHS Foundation Trust | Observational | Not yet recruiting | Congenital Heart Disease | 300 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07112794) |
| July 31, 2025 | NCT07095829 | Prognostic Model of Postnatal Circulation in Pulmonary Atresia-critical Stenosis With Intact Ventricular Septum | Hospital Universitario 12 de Octubre | Observational | Recruiting | Pulmonary Atresia With Intact Ventricular Septum, Congenital Heart Disease, Fetal Cardiac Disorder | 150 | Spain, Sweden | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07095829) |
| July 30, 2025 | NCT07092644 | Preeclampsia and Fetal Heart Malformations: Looking to Maternal Heart | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | Not applicable | Recruiting | Congenital Heart Disease | 108 | Italy | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07092644) |
| July 28, 2025 | NCT07089264 | Physical Rehabilitation in Patients With Complex Congenital Heart Disease | Hospital do Coracao | Not applicable | Active not recruiting | Congenital Heart Disease (CHD) | 20 | Brazil | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07089264) |
| July 23, 2025 | NCT07081711 | Longitudinal Validation of CIRC Technologies | The Cleveland Clinic | Observational | Recruiting | Cardiovascular Diseases, Heart Failure, Ischemic Heart Disease, Non-ischemic Cardiomyopathy, Valvular Heart Disease... | 1,000 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07081711) |

## Sponsors posting most

| Sponsor | New trials | Latest |
| --- | --- | --- |
| Assiut University | 12 | October 8, 2026 |
| IRCCS Azienda Ospedaliero-Universitaria di Bologna | 6 | January 20, 2025 |
| University Hospital, Bordeaux | 5 | December 23, 2025 |
| Children's Hospital of Fudan University | 4 | October 28, 2026 |
| China National Center for Cardiovascular Diseases | 4 | September 28, 2026 |
| Xinhua Hospital, Shanghai Jiao Tong University School of Medicine | 4 | August 3, 2026 |
| Boston Children's Hospital | 4 | July 15, 2026 |
| Baskent University | 3 | September 24, 2026 |
| Kun Sun | 3 | September 21, 2026 |
| University Medical Centre Ljubljana | 3 | August 18, 2026 |
| The University of Hong Kong | 3 | June 23, 2026 |
| The Children's Hospital of Zhejiang University School of Medicine | 3 | May 18, 2026 |
| Beijing Anzhen Hospital | 3 | April 13, 2026 |
| Charite University, Berlin, Germany | 3 | March 20, 2026 |
| Cairo University | 3 | January 8, 2026 |
| Nantes University Hospital | 3 | June 13, 2025 |
| Yan Fuxia | 3 | March 17, 2025 |
| Universitas Indonesia | 2 | November 9, 2026 |
| The Hospital for Sick Children | 2 | October 27, 2026 |
| CardioVision International Tech, S.A.S. de C.V. | 2 | September 23, 2026 |

## By phase

| Phase | New trials | Latest |
| --- | --- | --- |
| [Not applicable](https://specstream.ai/data/clinical-trials/phase/not-applicable) | 77 | October 27, 2026 |
| [Observational](https://specstream.ai/data/clinical-trials/phase/observational) | 74 | November 9, 2026 |
| [Phase 4](https://specstream.ai/data/clinical-trials/phase/phase-4) | 4 | September 24, 2026 |
| [Phase 1/2](https://specstream.ai/data/clinical-trials/phase/phase-1-2) | 4 | March 20, 2026 |
| [Phase 3](https://specstream.ai/data/clinical-trials/phase/phase-3) | 2 | May 2, 2025 |
| [Phase 2](https://specstream.ai/data/clinical-trials/phase/phase-2) | 1 | March 27, 2026 |

## By country

| Country | New trials | Latest |
| --- | --- | --- |
| [China](https://specstream.ai/data/clinical-trials/country/china) | 28 | October 2, 2026 |
| [United States](https://specstream.ai/data/clinical-trials/country/united-states) | 24 | October 8, 2026 |
| [France](https://specstream.ai/data/clinical-trials/country/france) | 14 | October 7, 2026 |
| [Italy](https://specstream.ai/data/clinical-trials/country/italy) | 10 | May 29, 2026 |
| [Germany](https://specstream.ai/data/clinical-trials/country/germany) | 9 | August 27, 2026 |
| [Turkey (Türkiye)](https://specstream.ai/data/clinical-trials/country/turkey-t-rkiye) | 8 | October 2, 2026 |
| [Canada](https://specstream.ai/data/clinical-trials/country/canada) | 6 | October 27, 2026 |
| [United Kingdom](https://specstream.ai/data/clinical-trials/country/united-kingdom) | 6 | August 27, 2026 |
| [Egypt](https://specstream.ai/data/clinical-trials/country/egypt) | 6 | May 8, 2026 |
| [Indonesia](https://specstream.ai/data/clinical-trials/country/indonesia) | 4 | November 9, 2026 |
| [Hong Kong](https://specstream.ai/data/clinical-trials/country/hong-kong) | 4 | June 23, 2026 |
| [Netherlands](https://specstream.ai/data/clinical-trials/country/netherlands) | 4 | May 29, 2026 |
| [Switzerland](https://specstream.ai/data/clinical-trials/country/switzerland) | 3 | August 3, 2026 |
| [Sweden](https://specstream.ai/data/clinical-trials/country/sweden) | 3 | February 19, 2026 |
| [Japan](https://specstream.ai/data/clinical-trials/country/japan) | 2 | October 20, 2026 |
| [United Arab Emirates](https://specstream.ai/data/clinical-trials/country/united-arab-emirates) | 2 | August 27, 2026 |
| [Slovenia](https://specstream.ai/data/clinical-trials/country/slovenia) | 2 | August 18, 2026 |
| [Iraq](https://specstream.ai/data/clinical-trials/country/iraq) | 2 | April 27, 2026 |
| [Brazil](https://specstream.ai/data/clinical-trials/country/brazil) | 2 | March 19, 2026 |
| [Spain](https://specstream.ai/data/clinical-trials/country/spain) | 2 | February 20, 2026 |
| [South Korea](https://specstream.ai/data/clinical-trials/country/south-korea) | 2 | April 4, 2025 |
| [Taiwan](https://specstream.ai/data/clinical-trials/country/taiwan) | 2 | March 12, 2025 |
| [Pakistan](https://specstream.ai/data/clinical-trials/country/pakistan) | 2 | February 12, 2025 |
| [Serbia](https://specstream.ai/data/clinical-trials/country/serbia) | 1 | August 27, 2026 |
| [Finland](https://specstream.ai/data/clinical-trials/country/finland) | 1 | August 25, 2026 |

## Where the register publishes

- [ClinicalTrials.gov](https://clinicaltrials.gov/)
- [ClinicalTrials.gov API](https://clinicaltrials.gov/data-api/api)

Source: [ClinicalTrials.gov API v2 (U.S. National Library of Medicine)](https://clinicaltrials.gov/data-api/api). U.S. government data; ClinicalTrials.gov terms of use. Studies are as their sponsors registered them on ClinicalTrials.gov, read through its API. Condition groups are the MeSH terms ClinicalTrials.gov assigns to each study's conditions; a study with several is in several groups. Sponsor class is the register's class of the lead sponsor. The central contact is in the full list only as the record prints it.

Free to reuse with credit to SpecStream under [CC BY 4.0](https://creativecommons.org/licenses/by/4.0/).