# Gastroesophageal Reflux trials: 143 new since Nov 2024

Updated November 6, 2026.

143 clinical studies in Gastroesophageal Reflux were first posted on ClinicalTrials.gov from November 12, 2024 to November 6, 2026; 32 have an industry sponsor and 87 are recruiting or about to. The newest, NCT07920679, was posted on November 6, 2026: Efficacy and Safety of K-CAB(Tegoprazan) 25 mg as Maintenance Therapy Following the Treatment of GERD (HK inno.N Corporation).

## The full list

New Gastroesophageal Reflux clinical trials: 143 rows for $7.15, first posted on ClinicalTrials.gov from November 12, 2024 to November 9, 2026. Columns: NCT ID, Title, Sponsor, Sponsor class, Phase, Status, Conditions, Condition groups (MeSH), Interventions, Start date, First posted, Enrollment, Enrollment type, Location countries, Central contact, Contact phone, Contact email, Last update posted, Read on, Source. The new rows each week by email, about 8 rows a month: $19 a month. Pay by card with no account. Prices exclude VAT. CSV and Excel files with the columns this page does not show (central contact, contact phone, contact email, sponsor class, condition groups (MeSH), interventions and 5 more), which open on your screen as soon as the payment clears and come by email. The rows on this page are a sample.

Buy: https://specstream.ai/data/clinical-trials/condition/gastroesophageal-reflux

SpecStream is the live web data engine for teams and agents. It reads every new study on ClinicalTrials.gov each morning, and this page is that reading. Ask for the conditions, phases or countries you follow and each new trial arrives in your sheet, CRM, Slack or agent with the sponsor, the sites and the listed contact.

- New trials: 143
- Industry sponsored: 32
- Recruiting or not yet: 87
- Latest posted: November 6, 2026

## Newest trials

The newest 100 of 143, each linked to its record. The full list holds every one with the sponsor class, interventions, start date and the central contact as the record prints it.

| First posted | NCT ID | Title | Sponsor | Phase | Status | Conditions | Enrollment | Countries | Source |
| --- | --- | --- | --- | --- | --- | --- | --- | --- | --- |
| November 6, 2026 | NCT07920679 | Efficacy and Safety of K-CAB(Tegoprazan) 25 mg as Maintenance Therapy Following the Treatment of GERD | HK inno.N Corporation | Observational | Recruiting | Maintenance Therapy Following Treatment for Gastroesophageal Reflux Disease(GERD) | 12,868 | South Korea | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07920679) |
| November 5, 2026 | NCT07919522 | The Prospective Observational Study Evaluating the Clinical Profile and Correlation of Subjective and Objective Parameters of GERD in a... | Asian Institute of Gastroenterology, India | Observational | Completed | GERD | 50 | India | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07919522) |
| November 2, 2026 | NCT07910656 | PDO Thread Embedding Plus Binh Vi Tablets for Gastroesophageal Reflux Disease | University of Medicine and Pharmacy at Ho Chi Minh City | Not applicable | Completed | Gastroesophageal Reflux Disease (GERD) | 86 | Vietnam | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07910656) |
| October 29, 2026 | NCT07902895 | Intrathoracic Sleeve Migration (Sliding Hiatal Hernia) One Year or More After Laparoscopic Sleeve Gastrectomy | Kasr El Aini Hospital | Observational | Completed | Hiatal Hernia, Gastroesophageal Reflux Disease, Obesity, Postoperative Complications | 61 | Egypt | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07902895) |
| October 26, 2026 | NCT07893457 | Effects of Tirzepatide on Esophagogastric Junction Mechanics, Reflux Burden, and Gastric Physiology in Adults With Obesity | Mayo Clinic | Phase 4 | Not yet recruiting | Obese Adults | 30 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07893457) |
| October 23, 2026 | NCT07891455 | Sedation Depth and EGJ Endoscopic Grading: A Randomized Controlled Trial | Mohamed Abd El-Raouf Tawfik | Not applicable | Completed | Gerd, Esophagogastric Junction, American Foregut Society Classification | 192 | Egypt | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07891455) |
| October 9, 2026 | NCT07868562 | Gastroesophageal Reflux and Respiratory Function in Patients Undergoing Abdominoplasty | Universidade Federal de Pernambuco | Observational | Not yet recruiting | Abdominoplasty, Diaphragm, Respiratory Mechanics, Gastroesophageal Reflux Disease | 30 | Brazil | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07868562) |
| October 2, 2026 | NCT07854613 | De Novo Gastroesophageal Reflux Disease After Sleeve Gastrectomy With and Without Omentopexy | China-Japan Friendship Hospital | Not applicable | Not yet recruiting | Omentopexy, Sleeve Gastrectomy, Gastroesophageal Reflux Disease | 140 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07854613) |
| October 1, 2026 | NCT07852676 | Effect of Bioflor on Gut Microbiota in Proton-Pump Inhibitor Users | Seoul National University Hospital | Phase 4 | Completed | Dysbiosis, Gastroesophageal Reflux Disease (GERD) | 80 | South Korea | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07852676) |
| October 1, 2026 | NCT07850960 | Effect of Omeprazole on Gut Microbiota in Adults With Obesity and GERD | Federal State Budgetary Scientific Institution | Phase 4 | Not yet recruiting | Obesity & Overweight, Gastroesophageal Reflux Disease | 26 | Russia | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07850960) |
| September 25, 2026 | NCT07842354 | Antireflux Mucosal Ablation vs Fundoplication for Refractory GERD | Minia University | Observational | Completed | Antireflux Mucosal Ablation, Laparoscopic Fundoplication Procedure, Refractory GERD, Endoscopic Therapy | 200 | Egypt | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07842354) |
| September 17, 2026 | NCT07826455 | A Study to Evaluate Tegoprazan as a Diagnostic Tool for GERD | HK inno.N Corporation | Phase 4 | Not yet recruiting | GERD (Gastroesophageal Reflux Disease) | 100 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07826455) |
| September 10, 2026 | NCT07814027 | POEM Versus Laparoscopic Heller Myotomy With Dor Fundoplication for Esophageal Achalasia | Minia University | Not applicable | Recruiting | Esophageal Achalasia, Esophageal Motility Disorders, Gastroesophageal Reflux | 220 | Egypt | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07814027) |
| September 9, 2026 | NCT07809620 | Preoperative Predictors of Symptom Improvement After Laparoscopic Fundoplication | Minia University | Observational | Recruiting | Gastroesophageal Reflux Disease, Hiatal Hernia, Esophagitis, Peptic, Barrett Esophagus | 470 | Egypt | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07809620) |
| September 1, 2026 | NCT07797959 | Thread-Embedding Acupuncture as an Adjunct to Proton Pump Inhibitor Therapy for Gastroesophageal Reflux Disease | University of Science Ho Chi Minh City | Not applicable | Recruiting | GERD, Gastroesophageal Reflux Disease | 50 | Vietnam | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07797959) |
| August 31, 2026 | NCT07795645 | Validating a Medical AI Fine-Tuning Platform for Major Diseases | Beijing Friendship Hospital | Observational | Recruiting | Chronic Gastritis, Gastric Cancer (GC), Coronary Artery Disease, Stroke, Gastro Esophageal Reflux | 96,000 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07795645) |
| August 17, 2026 | NCT07768202 | AJYR+GV vs RYGB for GERD | Victor Dib Institute | Not applicable | Active not recruiting | Obesity, Morbid, Gastroesophageal Reflux (GERD) | 60 | Brazil | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07768202) |
| August 11, 2026 | NCT07757776 | A Prospective, Multicenter, Single-Arm Study to Support the Clinical Evidence Base for MRace as a Treatment Option for FMR Patients With... | Polares Medical SA | Not applicable | Not yet recruiting | Mitral Valve (MV) Regurgitation | 20 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07757776) |
| August 11, 2026 | NCT07757698 | A Prospective, Multicenter, Single-Arm Study to Support the Clinical Evidence Base for MRace as a Treatment Option for FMR Patients With... | Polares Medical SA | Not applicable | Not yet recruiting | Mitral Valve (MV) Regurgitation | 15 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07757698) |
| August 11, 2026 | NCT07757607 | A Prospective, Multicenter, Single-Arm Study to Support the Clinical Evidence Base for MRace as a Treatment Option for FMR Patients With... | Polares Medical SA | Not applicable | Not yet recruiting | Mitral Valve (MV) Regurgitation | 20 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07757607) |
| August 10, 2026 | NCT07754721 | Comprehensive Management Strategies for Gastroesophageal Reflux Disease: A Study of Multidimensional Interventions and Health Impacts | Hualien Tzu Chi General Hospital | Not applicable | Recruiting | Disorders of Gut-brain Interaction, Lifestyle and Dietary Interventions, Gastroesophageal Reflux Disease | 220 | Taiwan | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07754721) |
| August 7, 2026 | NCT07752407 | A Study to Evaluate the Efficacy and Safety of Vonoprazan 10 mg Compared to Placebo for Relief of Episodic Heartburn in Participants With... | Phathom Pharmaceuticals, Inc. | Phase 3 | Recruiting | Symptomatic Non-erosive Gastroesophageal Reflux Disease | 500 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07752407) |
| August 6, 2026 | NCT07750379 | Assessing the Role of Proton Pump Inhibitors in Reducing Aspiration Incidence in Pediatric Laryngomalacia Cases | Minia University | Not applicable | Recruiting | Laryngomalacia | 60 | Egypt | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07750379) |
| August 6, 2026 | NCT07749989 | A Retrospective Analysis of Patients With Gastroesophageal Reflux Disease Based on a Prospective Clinical Dataset | Beijing Friendship Hospital | Observational | Recruiting | Gastroesophageal Reflux Disease | 5,000 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07749989) |
| August 6, 2026 | NCT07749352 | One-year Clinical Outcomes of Endoscopic Cardia Banding Plication for Refractory Gastroesophageal Reflux Disease After Laparoscopic Sleeve... | China-Japan Friendship Hospital | Not applicable | Completed | Gastroesophageal Reflux Disease (GERD) | 47 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07749352) |
| August 4, 2026 | NCT07744815 | Mobile Application for Gastroesophageal Reflux Disease | Fooyin University | Not applicable | Completed | Gastroesophageal Reflux Esophagitis | 90 | Taiwan | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07744815) |
| July 27, 2026 | NCT07728682 | Transit Bipartition After Sleeve Gastrectomy | Hospital das Clínicas de Ribeirão Preto | Not applicable | Not yet recruiting | Obesity & Overweight, Gastroesophageal Reflux (GERD), Weight Recurrence, Bariatric Surgery | 40 | Brazil | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07728682) |
| July 24, 2026 | NCT07726173 | Transventricular Off-pump Mitral Valve Repair | Johns Hopkins University | Not applicable | Recruiting | Mitral Valve (MV) Regurgitation | 175 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07726173) |
| July 23, 2026 | NCT07722663 | Endoscopic Classification of Fundoplication Integrity Predicts Pathologic Reflux | IRCCS Policlinico S. Donato | Observational | Completed | Gastro Esophageal Reflux | 153 | Italy | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07722663) |
| July 22, 2026 | NCT07718828 | Laparoscopic Nissen Versus Toupet Fundoplication for Hiatal Hernia. | Sofia Med Hospital | Not applicable | Recruiting | Hiatal Hernia, Paraesophageal, Hiatal Hernia Large, Hiatal Hernia With Gastroesophageal Reflux Disease | 200 | Bulgaria | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07718828) |
| July 21, 2026 | NCT07716592 | PROPER-GERD: A Prospective Crossover Study to Evaluate Probe Placement Optimization for Reflux Testing in Women and Lower-BMI Patients | University of Chicago | Not applicable | Not yet recruiting | GERD | 80 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07716592) |
| July 17, 2026 | NCT07712614 | A Comparison of Cosmos Rx Medication Adherence Platform vs. Pharmacy Fill Adherence Measures | Cosmos Rx, Inc | Not applicable | Not yet recruiting | GERD (Gastroesophageal Reflux Disease) | 50 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07712614) |
| July 17, 2026 | NCT07711912 | POLAR-STUDY: Polish AntiReflux Study | University of Warmia and Mazury in Olsztyn | Observational | Enrolling by invitation | Reflux Disease, Gastro-Esophageal | 200 | Poland | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07711912) |
| July 16, 2026 | NCT07707011 | Potassium Competitive Acid Blocker (PCAB) Test-Guided vs Physiologic Test-Guided Treatment in Patients With Typical Reflux Symptoms | Mahidol University | Not applicable | Enrolling by invitation | GERD, Acid Reflux, Treatment | 120 | Thailand | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07707011) |
| July 15, 2026 | NCT07705425 | EPX-HTG for Structural Heart Procedures | EchoPixel, Inc. | Not applicable | Not yet recruiting | Atrial Fibrillation (AF), Mitral Valve (MV) Regurgitation | 20 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07705425) |
| July 14, 2026 | NCT07700342 | QUality of Sleep Improvement With Evening Topical Therapy for Non-Erosive Gastroesophageal Reflux Disease (The QUIET Trial) | Cellmedis | Not applicable | Recruiting | Nocturnal Symptoms of GERD, Sleep Disorders in GERD, GERD (Gastroesophageal Reflux Disease), Non-Erosive... | 50 | Poland | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07700342) |
| July 1, 2026 | NCT07678177 | An Observational Study to Evaluate the Efficacy and Safety of K-CAB Tab./K-CAB ODT(Tegoprazan) in GERD Patients | HK inno.N Corporation | Observational | Recruiting | GERD (Gastroesophageal Reflux Disease) | 5,384 | South Korea | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07678177) |
| June 25, 2026 | NCT07667894 | Mindfulness Intervention for Emotional Distress (MIED) in Patients With GERD | Xinghua Liu | Not applicable | Recruiting | Gastroesophageal Reflux Disease, Emotional Distress | 500 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07667894) |
| June 22, 2026 | NCT07659080 | Antireflux Surgery Without Preoperative Esophageal Manometry | McMaster University | Not applicable | Not yet recruiting | GERD, Hiatal Hernia, Heartburn, Paraesophageal Hernia, Gastroesophageal Reflux | 96 | Canada, United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07659080) |
| June 12, 2026 | NCT07643779 | Symptom Severity, Posture, Pain, and Physical Activity in Gastroesophageal Reflux Disease | Karabuk University | Observational | Recruiting | Gastroesophageal Reflux Disease (GERD), Symptom, Musculoskeletal Pain, Physical Activity | 51 | Turkey (Türkiye) | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07643779) |
| June 10, 2026 | NCT07638423 | Endoscopic Injection of Autologous Fat-Derived Cells (SVF) for Adults With Refractory Gastroesophageal Reflux Disease (GERD). (The... | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | Not applicable | Not yet recruiting | GERD (Gastroesophageal Reflux Disease) | 15 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07638423) |
| June 9, 2026 | NCT07634614 | Pre- and Post-Therapy Evaluation of Air-Associated Symptoms in Patients With Gastro-esophageal Reflux Disease (GERD): Assessing the Role of... | Prof Urs Zingg | Observational | Enrolling by invitation | GERD | 100 | Switzerland | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07634614) |
| June 3, 2026 | NCT07624383 | New Topical tReatment Options for Symptomatic patiEnts With Nonerosive gastroesophageaL Reflux dIsease (The RELIEF Trial) | Cellmedis | Not applicable | Recruiting | GERD (Gastroesophageal Reflux Disease), NERD, Heartburn, Regurgitation, Gastric | 50 | Poland | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07624383) |
| June 2, 2026 | NCT07620899 | Biological Optimization Versus Standard Care in Post-POEM Achalasia Patients (BIO-POEM) | Asian Institute of Gastroenterology, India | Not applicable | Active not recruiting | Achalasia Cardia, GERD (Gastroesophageal Reflux Disease) | 166 | India | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07620899) |
| May 26, 2026 | NCT07607067 | Pilot Study of Salivary Bile Acids and Pepsin as Predictive Biomarkers of Reflux Disease After Sleeve Gastrectomy | Hospital de Mataró | Observational | Not yet recruiting | Reflux Disease, Gastro-Esophageal, Sleeve Gastrectomy, Saliva Collection, Reflux Esophagitis (RE), Barrett Esophagus | 60 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07607067) |
| May 20, 2026 | NCT07600008 | Development of a Preparation for Supportive Supplementation of Probiotics in Patients With Reflux | University Hospital Olomouc | Early phase 1 | Recruiting | Reflux Disease, Microbiome, Probiotics Supplement | 50 | Czechia | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07600008) |
| May 7, 2026 | NCT07573852 | ECG and CXR for Predicting Cardiovascular Diseases | Shanghai Zhongshan Hospital | Observational | Completed | Valvular Heart Diseases, Valvular Heart Disease Stenosis and Regurgitation, Regurgitation, Aortic Valve, Regurgitation... | 116,380 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07573852) |
| May 7, 2026 | NCT07573280 | Effects of Clinical Pilates Exercises on Symptoms, Posture, Balance and Quality of Life in GERD | Istinye University | Not applicable | Completed | Pilates Exercise, Gastro Esophageal Reflux | 33 | Turkey (Türkiye) | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07573280) |
| May 4, 2026 | NCT07563790 | A Pre-market, Two-stages Interventional Clinical Investigation to Evaluate the Safety and the Performance of Fibroin Syrup in Reducing the... | Rose Pharma SA | Not applicable | Completed | GERD (Heartburn, Regurgitation, and Dyspepsia), Gastroesophageal Reflux (GERD) | 47 | Italy | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07563790) |
| May 4, 2026 | NCT07563491 | Comparison of Esomeprazole Versus Vonoprazan in Gastroesophageal Reflux Disease | Muhammad Aamir Latif | Not applicable | Completed | Gastro Esophageal Reflux | 824 | Pakistan | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07563491) |
| May 1, 2026 | NCT07560787 | Impact of Crural Repair and Gastropexy During Laparoscopic Sleeve Gastrectomy | Van Training and Research Hospital | Not applicable | Completed | Obesity, Morbid, Gastroesophageal Reflux Disease | 50 | Turkey (Türkiye) | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07560787) |
| April 29, 2026 | NCT07556289 | Transoral Incisional Fundoplication (TIF) for Patients Suffering From Gastroesophageal Reflux Disease in an Asian Population | Chinese University of Hong Kong | Phase 2 | Recruiting | Fundoplication, GERD | 20 | Hong Kong | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07556289) |
| April 22, 2026 | NCT07544433 | Diaphragmatic Training on GERD | Changhua Christian Hospital | Not applicable | Recruiting | GERD, Diaphragmatic Training | 42 | Taiwan | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07544433) |
| April 17, 2026 | NCT07537244 | Impact of GEA Simultaneous to VSG on Post-operative GERD | Clinica Gastrobese | Not applicable | Active not recruiting | Obesity, Reflux, Gastroesophageal | 60 | Brazil | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07537244) |
| April 2, 2026 | NCT07506746 | PRospective Registry of Esophageal Motility | IRCCS San Raffaele | Observational | Recruiting | Esophageal Diseases, Achalasia, Eosinophilic Esophagitis, Motility Disorder, GERD | 10,000 | Italy | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07506746) |
| April 1, 2026 | NCT07506356 | Investigation of Gastric Emptying by Gastric Ultrasonography in Diabetic Patients Treated With GLP-1 Receptors | University Hospital, Geneva | Observational | Recruiting | Diabete Type 2, Regurgitation, Pulmonary Aspiration During Anaesthetic Induction | 38 | Switzerland | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07506356) |
| March 19, 2026 | NCT07482969 | Prevalence of Symptomatic Gastroesophageal Reflux Disease in Czech Children (Czech GERDKids) | University Hospital, Motol | Observational | Recruiting | Gastro Esophageal Reflux | 1,000 | Czechia | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07482969) |
| March 4, 2026 | NCT07449728 | The Influence of Laser Crossectomy With Different Wavelengths on Varicose Vein Progression | Pirogov Russian National Research Medical University | Not applicable | Recruiting | Varicose Veins, Chronic Venous Insufficiency | 400 | Russia | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07449728) |
| February 27, 2026 | NCT07437768 | Vonoprazan Test for PPI Refractory GERD | Fu Jen Catholic University Hospital | Not applicable | Enrolling by invitation | Refractory GERD, NERD, PCAB | 100 | Taiwan | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07437768) |
| February 19, 2026 | NCT07421011 | Pharmacokinetics, Bioequivalence, and Safety Study of Trimedat® 76,95 mg Orally Disintegrating Tablets and Trimedat® 100 mg Tablets in... | Valenta Pharm JSC | Phase 1 | Recruiting | Irritable Bowel Syndrome, Gallstone Disease, GERD, Biliary Dyskinesia, Postcholecystectomy Syndrome | 36 | Russia | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07421011) |
| February 9, 2026 | NCT07395219 | European TIF2.0 Registry | Cleveland Clinic London | Observational | Enrolling by invitation | Gastro -Oesophagal Reflux, Laryngo-pharyngeal Reflux | 500 | Austria, Italy, Serbia, Switzerland, Turkey (Türkiye), United Arab Emirates... | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07395219) |
| February 2, 2026 | NCT07380932 | Catheter Ablation for AF in Patients With Severe Mitral Regurgitation After Successful Transcatheter Mitral-Valve Repair | Atrial Fibrillation Network | Not applicable | Not yet recruiting | Atrial Fibrillation (AF), Mitral Valve (MV) Regurgitation | 956 | Germany | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07380932) |
| January 30, 2026 | NCT07379645 | A Clinical Trial of PepZinGI® for Acute Heartburn Relief and Sleep Outcomes | NutriScience Innovations, LLC | Not applicable | Completed | Heartburn | 50 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07379645) |
| January 23, 2026 | NCT07364838 | Study to Evaluate the Effect of Food on the Pharmacokinetics and Pharmacodynamics Characteristics in Healthy Adult Volunteers | Daewon Pharmaceutical Co., Ltd. | Phase 1 | Completed | GERD (Gastroesophageal Reflux Disease) | 24 | South Korea | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07364838) |
| January 15, 2026 | NCT07344935 | Evaluation of the Effectiveness of the Ezisurg Stapling (Ezi Endo Lite) During Laparoscopic Nissen Sleeve Gastrectomy | Ezisurg Medical Co. Ltd. | Not applicable | Completed | Gastroesophageal Reflux Disease (GERD) | 167 | France | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07344935) |
| January 13, 2026 | NCT07338448 | Electrical Acupoint Stimulation on Gastric Reflux During I-gel Ventilation | Air Force Military Medical University, China | Not applicable | Not yet recruiting | Anesthesia | 116 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07338448) |
| January 8, 2026 | NCT07326904 | Study Comparing Fexuprazan and Esomeprazole in Patients With Gastroesophageal Reflux Disease | Universitas Indonesia | Phase 3 | Completed | Gastro Oesophageal Reflux Disease | 145 | Indonesia | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07326904) |
| January 2, 2026 | NCT07313774 | A Study Comparing the Effect and Safety of Linaprazan Glurate to Lansoprazole in Maintenance of Healing in Participants With Healed Erosive... | Cinclus Pharma Holding AB | Phase 3 | Withdrawn | GERD (Gastroesophageal Reflux Disease) | 0 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07313774) |
| December 30, 2025 | NCT07310927 | Alginate vs Sucralfate for GERD Symptomatic Relief | CMH Lahore Medical College and Institute of Dentistry | Phase 2/3 | Completed | GERD | 140 | Pakistan | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07310927) |
| December 29, 2025 | NCT07308041 | A Study to Investigate the Effect of Linaprazan Glurate on the Pharmacokinetics of Amoxicillin | Cinclus Pharma Holding AB | Phase 1 | Completed | Drug Interaction, GERD (Gastroesophageal Reflux Disease), Safety, and Tolerability | 12 | Sweden | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07308041) |
| December 18, 2025 | NCT07291700 | Study on Hydrotalcite for Relief of Acid Symptoms Due to Acid Rebound After Stopping Long-Term PPI Therapy | Bayer | Observational | Recruiting | Gastroesophageal Reflux | 167 | Germany | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07291700) |
| December 8, 2025 | NCT07268820 | Heartburn, Gastroesophageal Reflux Disease | Incheon St.Mary's Hospital | Phase 4 | Recruiting | GERD | 160 | South Korea | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07268820) |
| December 5, 2025 | NCT07267117 | Cohort Observing Mechanisms, Progression and Sequelae of Valvular Heart Disease | Second Affiliated Hospital, Zhejiang University, School of Medicine | Observational | Recruiting | Heart Valve Disease, Mitral Valve (MV) Regurgitation, Mitral Valve Disease, Mitral Valve Stenosis, Aortic Valve... | 10,000 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07267117) |
| November 26, 2025 | NCT07252180 | Comparing Two Different Methods of Ablation of Inlet Patches (APC vs RFA) | Assaf-Harofeh Medical Center | Not applicable | Active not recruiting | GERD (Gastroesophageal Reflux Disease), Throat Disorders | 72 | Israel | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07252180) |
| November 26, 2025 | NCT07252115 | TLSA Versus TBSA Surgical Approach for Hiatal Hernia With Gastroesophageal Reflux Disease | Beijing Friendship Hospital | Not applicable | Recruiting | Hernia, Hiatal, GERD (Gastroesophageal Reflux Disease) | 143 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07252115) |
| November 26, 2025 | NCT07251660 | Comparison of Early Postoperative Outcomes Between Minimally Invasive Valve Surgery Via Right Thoracotomy and Conventional Valve Surgery... | Chaudhry Pervaiz Elahi Institute of Cardiology | Not applicable | Not yet recruiting | Heart Valve Diseases or Prosthesis, Aortic Valve Stenosis, Aortic Valve Insufficiency, Valvular Heart Disease Stenosis... | 32 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07251660) |
| November 26, 2025 | NCT07251010 | Phrenoesophageal Ligament Reconstruction With Mesh | Clinical Trial Aseer | Not applicable | Recruiting | Hiatus Hernia, Gastreoesophageal Reflux Disease | 60 | Saudi Arabia | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07251010) |
| November 21, 2025 | NCT07243197 | DragonFly M2 Pivotal Study | Hangzhou Valgen Medtech Co., Ltd | Not applicable | Not yet recruiting | Mitral Valve (MV) Regurgitation | 53 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07243197) |
| November 12, 2025 | NCT07227506 | Utility of Mucosal Impedance Device in Chronic Esophageal Disorders: | Medical College of Wisconsin | Observational | Recruiting | Gerd, Eosinophilic Esophagitis | 50 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07227506) |
| September 30, 2025 | NCT07199582 | Association Between Obesity and Gastroesophageal Reflux Disease | Assiut University | Observational | Not yet recruiting | Gastro Esophageal Reflux, Obesity (Disorder) | 200 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07199582) |
| September 17, 2025 | NCT07179250 | Effect of Breathing Training on Symptoms of Gastroesophageal Reflux Disease | Changhua Christian Hospital | Not applicable | Not yet recruiting | Incentive Spirometer, Diaphragmatic Breathing, Gastroesophageal Reflux Disease (GERD), Breath Exercise | 51 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07179250) |
| September 17, 2025 | NCT07178821 | Sling-Fiber Preservation POEM vs. Conventional POEM for Reducing Post-POEM GERD | University of California, Irvine | Not applicable | Not yet recruiting | Achalasia, Esophageal, GERD (Gastroesophageal Reflux Disease) | 120 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07178821) |
| September 16, 2025 | NCT07176221 | Endoscopic Cardial Constriction Ligation (ECCL) for Refractory GERD Using a Disposable Endoscope | Ying Zhu | Not applicable | Not yet recruiting | Gastroesophageal Reflux Disease (GERD) | 46 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07176221) |
| September 16, 2025 | NCT07174882 | Evaluation of the Clinical Course of NERD and Assessment of the Esophageal Mucosa Resistance | I.M. Sechenov First Moscow State Medical University | Observational | Active not recruiting | Non-Erosive Gastro-Esophageal Reflux Disease, Gastroesophageal Reflux Disease (GERD) | 60 | Russia | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07174882) |
| September 5, 2025 | NCT07158008 | Comparison of Nissen-Sleeve and Gastric Bypass for GERD in Obese Patients | Jagiellonian University | Not applicable | Recruiting | Gastro Esophageal Reflux, Severe Obesity, Bariatric Surgery | 560 | Poland | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07158008) |
| August 29, 2025 | NCT07148583 | BioAmicus Complete for Functional Gastrointestinal Symptoms in Infants Aged 0 to 24 Months | Haiphong University of Medicine and Pharmacy | Not applicable | Recruiting | Infantile Colic, Gastroesophageal Reflux (GER), Functional Constipation, Functional Diarrhea, Dysbiosis | 110 | Vietnam | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07148583) |
| August 29, 2025 | NCT07148492 | Antireflux Suture In One Anastomsis Gastric Bypass | Khyber Teaching Hospital | Not applicable | Recruiting | Reflux Disease, Gastro-Esophageal, Vomiting, Postoperative | 316 | Pakistan | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07148492) |
| August 20, 2025 | NCT07131397 | The Effect of Inspiratory Muscle Training in People With Gastroesophageal Reflux Disease | University of West Attica | Not applicable | Recruiting | Gastro Esophageal Reflux | 30 | Greece | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07131397) |
| August 17, 2025 | NCT07127276 | Evaluating Medication Adherence of Patients With Gastroesophageal Reflux Disease With Support of Smartphone Application GERDCare | Institute of Gastroenterology and Hepatology, Vietnam | Not applicable | Not yet recruiting | GERD (Gastroesophageal Reflux Disease) | 380 | Vietnam | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07127276) |
| August 15, 2025 | NCT07125638 | Long-term Follow-up After OAGB | Azienda Sanitaria Locale Napoli 2 Nord | Observational | Completed | Obesity, Morbid, Obesity, Abdominal, Ona Anastomosis Gastric Bypass, GERD, Bile Reflux Gastritis | 2,368 | Italy | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07125638) |
| August 15, 2025 | NCT07125521 | Evaluating Medication Adherence of Patients With Gastroesophageal Reflux Disease With Support of the Smartphone Application GERDCare | Institute of Gastroenterology and Hepatology, Vietnam | Not applicable | Recruiting | GERD (Gastroesophageal Reflux Disease) | 380 | Vietnam | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07125521) |
| August 14, 2025 | NCT07121803 | The Influence of Specialized Food Products Based on Ice-Cream on Esophageal Motility | Federal State Budgetary Scientific Institution | Not applicable | Recruiting | Ineffective Esophageal Motility, GERD (Gastroesophageal Reflux Disease) | 30 | Russia | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07121803) |
| August 13, 2025 | NCT07121062 | Validation Of A Parent Administered Symptom Score For Unsettled Infants (Every Baby is UnIQue) | University Hospital Southampton NHS Foundation Trust | Observational | Not yet recruiting | Colic, Infantile, Milk Allergy, Cow's, Gastro Oesophageal Reflux Disease, Atopic Dermatitis (Eczema), Constipation... | 350 | United Kingdom | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07121062) |
| August 7, 2025 | NCT07108751 | Association Between Gastroesophageal Reflux Disease (GERD) Severity and Dental Caries | Tanta University | Observational | Completed | Gastroesophageal Reflux Disease, Severity, Dental Caries | 200 | Egypt | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07108751) |
| August 6, 2025 | NCT07107672 | Mass Balance Study of \[14C\]X842 in Healthy Adult Male Subjects | Jiangsu Sinorda Biomedicine Co., Ltd | Phase 1 | Completed | Gastroesophageal Reflux Disease | 6 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07107672) |
| August 3, 2025 | NCT07102329 | BURDEN OF ESOPHAGEAL CANCER IN EOSINOPHILIC ESOPHAGITIS (ESCAPE STUDY) | IRCCS San Raffaele | Observational | Completed | Eosinophilic Esophagitis (EoE) | 100,000 | Italy | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07102329) |
| August 1, 2025 | NCT07099417 | Screening of Valvular Heart Disease Using Single-channel Electrocardiogram | I.M. Sechenov First Moscow State Medical University | Observational | Recruiting | Valvular Heart Disease Stenosis and Regurgitation, Valvular Heart Disease | 1,200 | Russia | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07099417) |
| July 30, 2025 | NCT07093359 | LINX vs Fundoplication | University of Oxford | Phase 3 | Recruiting | Gastro-oesophageal Reflux Disease | 460 | United Kingdom | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07093359) |
| July 17, 2025 | NCT07070908 | Modifications to Gastric Sleeve: Implications for GRED and Quality of Life | Hospital San Juan de Dios Tenerife | Not applicable | Active not recruiting | Obese Patients (BMI ≥ 30 kg/m²), Obese Patients, Obese Patients With Bariatric Surgery, Obese With Comorbidities | 120 | Spain | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07070908) |
| July 17, 2025 | NCT07069673 | Abbott Cephea Mitral Valve Disease Registry | Abbott Medical Devices | Observational | Recruiting | Mitral Regurgitation, Mitral Stenosis, Mitral Valve Disease, Mitral Valve (MV) Regurgitation, Mitral Annulus... | 1,000 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07069673) |

## Sponsors posting most

| Sponsor | New trials | Latest |
| --- | --- | --- |
| Asian Institute of Gastroenterology, India | 5 | November 5, 2026 |
| Minia University | 4 | September 25, 2026 |
| Beijing Friendship Hospital | 4 | August 31, 2026 |
| HK inno.N Corporation | 3 | November 6, 2026 |
| Polares Medical SA | 3 | August 11, 2026 |
| Hualien Tzu Chi General Hospital | 3 | August 10, 2026 |
| Cinclus Pharma Holding AB | 3 | January 2, 2026 |
| Universidade Federal de Pernambuco | 2 | October 9, 2026 |
| China-Japan Friendship Hospital | 2 | October 2, 2026 |
| Federal State Budgetary Scientific Institution | 2 | October 1, 2026 |
| Cellmedis | 2 | July 14, 2026 |
| Karabuk University | 2 | June 12, 2026 |
| Changhua Christian Hospital | 2 | April 22, 2026 |
| IRCCS San Raffaele | 2 | April 2, 2026 |
| Medical College of Wisconsin | 2 | November 12, 2025 |
| University of California, Irvine | 2 | September 17, 2025 |
| I.M. Sechenov First Moscow State Medical University | 2 | September 16, 2025 |
| Haiphong University of Medicine and Pharmacy | 2 | August 29, 2025 |
| Institute of Gastroenterology and Hepatology, Vietnam | 2 | August 17, 2025 |
| Implantica CE Reflux Ltd. | 2 | June 4, 2025 |

## By phase

| Phase | New trials | Latest |
| --- | --- | --- |
| [Not applicable](https://specstream.ai/data/clinical-trials/phase/not-applicable) | 76 | November 2, 2026 |
| [Observational](https://specstream.ai/data/clinical-trials/phase/observational) | 44 | November 6, 2026 |
| [Phase 4](https://specstream.ai/data/clinical-trials/phase/phase-4) | 8 | October 26, 2026 |
| [Phase 3](https://specstream.ai/data/clinical-trials/phase/phase-3) | 6 | August 7, 2026 |
| [Phase 1](https://specstream.ai/data/clinical-trials/phase/phase-1) | 5 | February 19, 2026 |
| [Phase 2](https://specstream.ai/data/clinical-trials/phase/phase-2) | 2 | April 29, 2026 |
| [Early phase 1](https://specstream.ai/data/clinical-trials/phase/early-phase-1) | 1 | May 20, 2026 |
| [Phase 2/3](https://specstream.ai/data/clinical-trials/phase/phase-2-3) | 1 | December 30, 2025 |

## By country

| Country | New trials | Latest |
| --- | --- | --- |
| [United States](https://specstream.ai/data/clinical-trials/country/united-states) | 18 | October 26, 2026 |
| [China](https://specstream.ai/data/clinical-trials/country/china) | 15 | October 2, 2026 |
| [South Korea](https://specstream.ai/data/clinical-trials/country/south-korea) | 10 | November 6, 2026 |
| [Egypt](https://specstream.ai/data/clinical-trials/country/egypt) | 10 | October 29, 2026 |
| [Italy](https://specstream.ai/data/clinical-trials/country/italy) | 10 | July 23, 2026 |
| [Vietnam](https://specstream.ai/data/clinical-trials/country/vietnam) | 6 | November 2, 2026 |
| [Brazil](https://specstream.ai/data/clinical-trials/country/brazil) | 6 | October 9, 2026 |
| [Russia](https://specstream.ai/data/clinical-trials/country/russia) | 6 | October 1, 2026 |
| [Taiwan](https://specstream.ai/data/clinical-trials/country/taiwan) | 6 | August 10, 2026 |
| [Turkey (Türkiye)](https://specstream.ai/data/clinical-trials/country/turkey-t-rkiye) | 6 | June 12, 2026 |
| [India](https://specstream.ai/data/clinical-trials/country/india) | 5 | November 5, 2026 |
| [Poland](https://specstream.ai/data/clinical-trials/country/poland) | 5 | July 17, 2026 |
| [Germany](https://specstream.ai/data/clinical-trials/country/germany) | 5 | February 2, 2026 |
| [Switzerland](https://specstream.ai/data/clinical-trials/country/switzerland) | 4 | June 9, 2026 |
| [United Kingdom](https://specstream.ai/data/clinical-trials/country/united-kingdom) | 4 | February 9, 2026 |
| [Czechia](https://specstream.ai/data/clinical-trials/country/czechia) | 3 | May 20, 2026 |
| [Pakistan](https://specstream.ai/data/clinical-trials/country/pakistan) | 3 | May 4, 2026 |
| [Bulgaria](https://specstream.ai/data/clinical-trials/country/bulgaria) | 2 | July 22, 2026 |
| [Thailand](https://specstream.ai/data/clinical-trials/country/thailand) | 2 | July 16, 2026 |
| [Austria](https://specstream.ai/data/clinical-trials/country/austria) | 2 | February 9, 2026 |
| [Serbia](https://specstream.ai/data/clinical-trials/country/serbia) | 2 | February 9, 2026 |
| [Spain](https://specstream.ai/data/clinical-trials/country/spain) | 2 | July 17, 2025 |
| [Canada](https://specstream.ai/data/clinical-trials/country/canada) | 1 | June 22, 2026 |
| [Hong Kong](https://specstream.ai/data/clinical-trials/country/hong-kong) | 1 | April 29, 2026 |
| [United Arab Emirates](https://specstream.ai/data/clinical-trials/country/united-arab-emirates) | 1 | February 9, 2026 |

## Where the register publishes

- [ClinicalTrials.gov](https://clinicaltrials.gov/)
- [ClinicalTrials.gov API](https://clinicaltrials.gov/data-api/api)

Source: [ClinicalTrials.gov API v2 (U.S. National Library of Medicine)](https://clinicaltrials.gov/data-api/api). U.S. government data; ClinicalTrials.gov terms of use. Studies are as their sponsors registered them on ClinicalTrials.gov, read through its API. Condition groups are the MeSH terms ClinicalTrials.gov assigns to each study's conditions; a study with several is in several groups. Sponsor class is the register's class of the lead sponsor. The central contact is in the full list only as the record prints it.

Free to reuse with credit to SpecStream under [CC BY 4.0](https://creativecommons.org/licenses/by/4.0/).