# New Dental Caries clinical trials: 223 posted since Nov 2024

Updated November 9, 2026.

223 clinical studies in Dental Caries were first posted on ClinicalTrials.gov from November 12, 2024 to November 9, 2026; 17 have an industry sponsor and 112 are recruiting or about to. The newest, NCT07926828, was posted on November 9, 2026: Silver Diamine Fluoride for Caries in Primary Teeth in Routine Clinical Practice (Consorci Sanitari de l'Alt Penedès i Garraf).

## The full list

New Dental Caries clinical trials: 223 rows for $11.15, first posted on ClinicalTrials.gov from November 12, 2024 to November 9, 2026. Columns: NCT ID, Title, Sponsor, Sponsor class, Phase, Status, Conditions, Condition groups (MeSH), Interventions, Start date, First posted, Enrollment, Enrollment type, Location countries, Central contact, Contact phone, Contact email, Last update posted, Read on, Source. The new rows each week by email, about 13 rows a month: $19 a month. Pay by card with no account. Prices exclude VAT. CSV and Excel files with the columns this page does not show (central contact, contact phone, contact email, sponsor class, condition groups (MeSH), interventions and 5 more), which open on your screen as soon as the payment clears and come by email. The rows on this page are a sample.

Buy: https://specstream.ai/data/clinical-trials/condition/dental-caries

SpecStream is the live web data engine for teams and agents. It reads every new study on ClinicalTrials.gov each morning, and this page is that reading. Ask for the conditions, phases or countries you follow and each new trial arrives in your sheet, CRM, Slack or agent with the sponsor, the sites and the listed contact.

- New trials: 223
- Industry sponsored: 17
- Recruiting or not yet: 112
- Latest posted: November 9, 2026

## Newest trials

The newest 100 of 223, each linked to its record. The full list holds every one with the sponsor class, interventions, start date and the central contact as the record prints it.

| First posted | NCT ID | Title | Sponsor | Phase | Status | Conditions | Enrollment | Countries | Source |
| --- | --- | --- | --- | --- | --- | --- | --- | --- | --- |
| November 9, 2026 | NCT07926828 | Silver Diamine Fluoride for Caries in Primary Teeth in Routine Clinical Practice | Consorci Sanitari de l'Alt Penedès i Garraf | Observational | Recruiting | Dental Caries | 101 | Spain | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07926828) |
| November 9, 2026 | NCT07926646 | Risk of Caries and Enamel Abnormalities in Patients With Cleft Palate | Cliniques universitaires Saint-Luc- Université Catholique de Louvain | Not applicable | Not yet recruiting | Dental Caries | 400 | Belgium | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07926646) |
| November 4, 2026 | NCT07916467 | Safety of Intraosseous Anaesthesia in Children With Haemophilia | Ankara Yildirim Beyazıt University | Not applicable | Not yet recruiting | Haemophilia A, Haemophilia B, Dental Caries | 20 | Turkey (Türkiye) | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07916467) |
| October 29, 2026 | NCT07903155 | Clinical and Radiographic Evaluation of Silver Diamine Fluoride Versus Light-Cured Silver Diamine Fluoride in Carious Primary Molars | Cairo University | Not applicable | Not yet recruiting | Dental Caries | 40 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07903155) |
| October 28, 2026 | NCT07902323 | Effect of Xylitol- Versus Erythritol-Sweetened Mints on Plaque ATP-Bioluminescence Readings | Loma Linda University | Not applicable | Not yet recruiting | Dental Caries, Dental Plaque | 80 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07902323) |
| October 26, 2026 | NCT07893756 | Evaluation of Silver Diamine Fluoride, Sodium Fluoride With Casein Phosphopeptide-Amorphous Calcium Phosphate(MI Varnish) and Dycal to... | University of Jazan | Phase 2 | Completed | Early Childhood Caries (ECC), Color Stability of Restoration, Caries Arrested, Caries,Dental | 90 | Saudi Arabia | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07893756) |
| October 21, 2026 | NCT07886255 | Color Stability of Darkly Discolored Arrested Caries Lesions Following Bleaching Treatment | Selcuk University | Observational | Completed | Dental Caries, Tooth Discoloration | 27 | Turkey (Türkiye) | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07886255) |
| October 20, 2026 | NCT07882914 | Dental Anxiety in Children Attending Emergency Versus Routine Dental Care | Marmara University | Observational | Completed | Dental Anxiety, Dental Fear | 47 | Turkey (Türkiye) | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07882914) |
| October 20, 2026 | NCT07882745 | This Feasibility Study Will Evaluate the Study Protocols for Treatment and Follow-up Controls of Primary Molars With Caries in Children... | Marie Norman | Not applicable | Not yet recruiting | Dental Caries, Early Childhood Caries (ECC) | 100 | Sweden | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07882745) |
| October 20, 2026 | NCT07882693 | The Effect of Bitewing Radiography on Outcomes and Costs of Treating Caries in Permanent Teeth | Jukka Leinonen | Not applicable | Not yet recruiting | Dental Caries, Teeth Loss, Necrosis of Pulp, Irreversible Pulpitis | 250 | Finland | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07882693) |
| October 19, 2026 | NCT07881380 | Oral Health Knowledge and Caries Experience in Adults | University of Las Palmas de Gran Canaria | Observational | Completed | Dental Caries | 80 | Spain | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07881380) |
| October 19, 2026 | NCT07880808 | Prevalence of Caries and Periodontal Disease and Their Correlation in a Dental School in Egypt | Cairo University | Observational | Completed | Periodontal Diseases, Dental Caries | 369 | Egypt | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07880808) |
| October 15, 2026 | NCT07876934 | Effect of Hemostatic Agents on TheraCal PT Pulpotomy Success in Primary Molars | Reem Mohamed Gaber | Not applicable | Not yet recruiting | Reversible Pulpitis, Dental Caries, Primary Molar Pulpotomy, Dental Pulp Exposure | 75 | Egypt | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07876934) |
| October 9, 2026 | NCT07869407 | Comparison of Intraoperative Pain Perception During Caries Excavation Using Smart Burs and Carisolv to Conventional Diamond Burs | Rehman Medical Institute - RMI | Not applicable | Recruiting | Pain During Caries Excavation | 66 | Pakistan | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07869407) |
| October 9, 2026 | NCT07868016 | Clinical Evaluation of Different Bulk-Fill Restorative Materials in Primary Molars | Burak Carıkcıoglu | Not applicable | Not yet recruiting | Decayed Primary Molars, Decayed Tooth, Dentin Caries | 70 | Turkey (Türkiye) | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07868016) |
| October 8, 2026 | NCT07866755 | Non-Restorative Versus Conventional Caries Treatment in Primary Teeth: A Randomized Controlled Trial | Lenka Likar Ostrc, DMD | Not applicable | Active not recruiting | Dental Caries, Primary Teeth | 96 | Slovenia | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07866755) |
| October 7, 2026 | NCT07864181 | TheraCal PT vs. Formocresol in Primary Molar Pulpotomies | Hama University | Phase 1/2 | Completed | Reversible Pulpitis | 50 | Syria | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07864181) |
| October 7, 2026 | NCT07863947 | Dental Caries and Related Factors in 6-Year-Old Schoolchildren in Chile: National Evidence for Assessment and Decision-Making (6yOH-Chile) | Universidad de los Andes, Chile | Observational | Completed | Dental Caries; Oral Health; Malocclusion | 2,484 | Chile | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07863947) |
| October 6, 2026 | NCT07861321 | A Study to Evaluate the Cariostatic Efficacy of Nano Silver Fluoride (NSF) vs. Silver Diamine Fluoride (SDF) in Children | A.T. Still University of Health Sciences | Not applicable | Recruiting | Dental Caries | 72 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07861321) |
| October 5, 2026 | NCT07859553 | Powered vs Manual Toothbrush Use: Its Effect on Caries Risk in Pre-Adolescents | University of Michigan | Not applicable | Recruiting | Caries Risk, Caries, Dental | 30 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07859553) |
| September 29, 2026 | NCT07846098 | Comparison of Intraosseous Anesthesia and Inferior Alveolar Nerve Block for Primary Mandibular Molars | Cumhuriyet University | Not applicable | Active not recruiting | Pain, Dental Caries | 30 | Turkey (Türkiye) | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07846098) |
| September 21, 2026 | NCT07831720 | Er:YAG Laser for Dental Cavity Preparation | Ho Chi Minh City Odonto-Stomatology Hospital | Not applicable | Not yet recruiting | Dental Caries | 20 | Vietnam | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07831720) |
| September 18, 2026 | NCT07828171 | Evaluation of Efficacy of Antibacterial Activity of Licorice, Clove, and Chlorohexidine Mouthwashes on Salivary Streptococcus Mutans in a... | British University In Egypt | Not applicable | Active not recruiting | Dental Caries, Streptococcal Infections, Mouthwashes | 54 | Egypt | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07828171) |
| September 14, 2026 | NCT07818226 | Effects of GLP-1 Receptor Agonists on Saliva and Oral Health | Kırıkkale University | Observational | Not yet recruiting | Type 2 Diabetes, Obesity & Overweight, Xerostomia, Dental Caries | 50 | Turkey (Türkiye) | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07818226) |
| September 10, 2026 | NCT07813065 | Repair Versus Replacement of Failed Restorations in Primary Teeth | University of Sao Paulo | Not applicable | Not yet recruiting | Dental Caries, Restoration Defects, Primary Teeth | 382 | Brazil | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07813065) |
| September 8, 2026 | NCT07808203 | A Comprehensive Oral Health Intervention Program for Preschool and Primary School Children in Suzhou | Soochow University | Not applicable | Not yet recruiting | Children, Dental Caries | 2,040 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07808203) |
| September 8, 2026 | NCT07807397 | Oral Hygiene Assistance Training Program | Colgate Palmolive | Phase 4 | Not yet recruiting | Elderly, Periodontal Disease, Gingivitis, Caries,Dental | 500 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07807397) |
| September 8, 2026 | NCT07806578 | Clinical Performance of Injectable and Conventional Resin Composites in Posterior Class I Restorations | Yuzuncu Yil University | Not applicable | Completed | Dental Caries | 38 | Turkey (Türkiye) | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07806578) |
| September 4, 2026 | NCT07803757 | Clinical Performance of High Viscous Glass Ionomer Cervical Restorations With Silver-Modified Atraumatic Restorative Technique (SMART)... | Cairo University | Not applicable | Not yet recruiting | Dental Caries, Cervical Caries | 30 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07803757) |
| August 26, 2026 | NCT07788274 | Zirconomer-P Versus RMGI for Proximal Restorations in Primary Molars | Cairo University | Not applicable | Not yet recruiting | Dental Caries | 50 | Egypt | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07788274) |
| August 26, 2026 | NCT07786805 | Bite Force Recovery Following Pediatric Full Crown Restorations | Tanta University | Not applicable | Not yet recruiting | Bite Force, Stainless-steel Crown, Masseter Muscle | 30 | Egypt | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07786805) |
| August 24, 2026 | NCT07781254 | Immersive Virtual Reality for Pain and Dental Anxiety During Pediatric Restorative Treatment | University of Gaziantep | Not applicable | Completed | Dental Anxiety in Children, Dental Pain, Virtual Reality, Distraction, Dental Caries | 70 | Turkey (Türkiye) | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07781254) |
| August 19, 2026 | NCT07774806 | Total Pulpotomy With Two Repair Cements in Hypomineralized Teeth | Meire Coelho Ferreira | Not applicable | Active not recruiting | Molar-Incisor Hypomineralization (MIH) | 120 | Brazil | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07774806) |
| August 19, 2026 | NCT07773805 | Clinical and Radiographic Success of Calcium Hydroxide-Iodoform Paste Versus Modified Triple Antibiotic Paste for Necrotic Primary Molars... | Cairo University | Not applicable | Not yet recruiting | Dental Pulp Necrosis, Periapical Diseases, Dental Caries, Primary Teeth | 50 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07773805) |
| August 18, 2026 | NCT07769697 | Comparative Clinical and Radiographic Evaluation of Different Pulpotomy Materials in Primary Molars | Inonu University | Not applicable | Completed | Dental Caries, Pulp Exposure, Dental, Primary Teeth, Primary Molar Pulpotomy | 140 | Turkey (Türkiye) | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07769697) |
| August 14, 2026 | NCT07765654 | WhatsApp Messages to Improve Mothers' Oral Health Knowledge and Children's Toothbrushing | King Abdulaziz University | Not applicable | Not yet recruiting | Oral Health, Dental Caries, Health Behavior, Oral Hygiene, Early Childhood Caries (ECC) | 106 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07765654) |
| August 13, 2026 | NCT07763470 | Polishing vs Hydrogen Peroxide: Effect on DIAGNOdent Readings in Stained Fissures | Özlem Erçin Sultanzade | Not applicable | Completed | Dental Caries, Occlusal Caries | 25 | Turkey (Türkiye) | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07763470) |
| August 13, 2026 | NCT07762651 | Clinical Evaluation of Dentin Replacement Materials in Posterior Composite Restorations | Tanta University | Not applicable | Enrolling by invitation | Dental Caries, Composite Resins, Composite Restoration | 30 | Egypt | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07762651) |
| August 6, 2026 | NCT07751016 | A Clinical Study of KH001 for Pulp Preservation and Safety in Deep Dentin Caries | Seoul National University Dental Hospital | Phase 2 | Not yet recruiting | Dental Caries | 36 | South Korea | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07751016) |
| August 4, 2026 | NCT07745803 | Discovery and Validation of Biomarkers for Periodontitis, Dental Caries and Oral Squamous Cell Carcinoma | Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University | Observational | Not yet recruiting | Oral Squamous Cell Carcinoma (OSCC), Periodontal Disease, Dental Caries | 4,000 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07745803) |
| August 3, 2026 | NCT07741409 | Povidone Iodine for Caries Prevention | Jeffrey A. Banas | Phase 3 | Not yet recruiting | Dental Caries | 174 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07741409) |
| July 24, 2026 | NCT07725757 | Caries of First Permanent Molars and Association With Dietary and Oral Habits Among a Group of Egyptian Children | October University for Modern Sciences and Arts | Observational | Not yet recruiting | Dental Caries | 272 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07725757) |
| July 24, 2026 | NCT07725133 | Clinical Evaluation of the Retention of Fissure Sealants Applied Following Guided Biofilm Therapy and Conventional Polishing | Marmara University | Not applicable | Not yet recruiting | Pit and Fissure Sealant Retention, Dental Caries | 80 | Turkey (Türkiye) | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07725133) |
| July 22, 2026 | NCT07720999 | Effect of Different Heating Protocols of Resin Composites on Pulp Condition (Randomized Controlled Trial) | Ain Shams University | Not applicable | Completed | Pulpal Inflammation, Dental Caries, Postoperative Pain | 30 | Egypt | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07720999) |
| July 22, 2026 | NCT07718412 | Children's Comfort With Isolite and Rubber Dam During Dental Treatment | Cumhuriyet University | Not applicable | Completed | Dental Caries | 66 | Turkey (Türkiye) | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07718412) |
| July 21, 2026 | NCT07716254 | Validation of a Digital Caries Risk Assessment Questionnaire Against the CAMBRA Protocol in an Egyptian Adult Population | October University for Modern Sciences and Arts | Observational | Recruiting | Dental Caries, Caries Risk | 384 | Egypt | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07716254) |
| July 16, 2026 | NCT07709247 | Salivary Cytokines, MMP-8 and Dental Caries in Osteoporosis Patients | Afyonkarahisar Health Sciences University | Observational | Completed | Osteoporosis, Dental Caries, Biomarkers, Matrix Metalloproteinase 8 | 30 | Turkey (Türkiye) | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07709247) |
| July 16, 2026 | NCT07708883 | Comparing Two Brands of Silver Diamine Fluoride for Stopping Cavities in Children | National Research Centre, Egypt | Not applicable | Active not recruiting | Dental Caries | 134 | Egypt | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07708883) |
| July 14, 2026 | NCT07703176 | Clinical and Radiographic Assessment of First Permanent Molars With Cention-N | Minia University | Not applicable | Recruiting | Dental Caries | 100 | Egypt | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07703176) |
| July 9, 2026 | NCT07691905 | Zirconia and Bioflx Crowns for Primary Anterior Teeth | Hue University of Medicine and Pharmacy | Not applicable | Active not recruiting | Dental Caries, Tooth Hypomineralization | 120 | Vietnam | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07691905) |
| July 8, 2026 | NCT07689838 | In-Vivo Diagnostic Accuracy and Repeatability of Root ZX3 for Working-Length Determination in Single-Rooted Teeth: Agreement With CBCT and... | Riyadh Elm University | Not applicable | Completed | Apical Periodontitis, Pulp Disease, Dental, Device Reliability, Device Performance | 41 | Saudi Arabia | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07689838) |
| July 7, 2026 | NCT07688343 | Clinical Performance of Different Ion-Releasing Restorative Systems in Class II Cavities | Mansoura University | Not applicable | Active not recruiting | Dental Caries | 40 | Egypt | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07688343) |
| July 6, 2026 | NCT07683910 | Sequential PVP-I and FV | Advantage Silver Dental Arrest, LLC | Observational | Not yet recruiting | Dental Caries | 393 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07683910) |
| June 30, 2026 | NCT07674888 | Breaking the Cycle: Real-Time Family Oral Microbial Transmission Patterns as Intervention Targets | University of Alberta | Not applicable | Not yet recruiting | Dental Caries, Periodontitis, Oral Microbiome, Bacterial Transmission | 225 | Canada | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07674888) |
| June 29, 2026 | NCT07673952 | Effect on Placement Tecnique of Bulkfill Composite | Hacettepe University | Not applicable | Active not recruiting | Dental Caries, Dental Restoration Failure | 50 | Turkey (Türkiye) | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07673952) |
| June 26, 2026 | NCT07671651 | Effect of Ozone Therapy on Remineralization of Initial Caries Lesions in Children | Neslihan Atmaca | Not applicable | Recruiting | Dental Caries, Early Caries Lesion | 80 | Turkey (Türkiye) | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07671651) |
| June 25, 2026 | NCT07667283 | Evaluating Methods of Dental Health Instructions on the Oral Health Indices of 12-18-year-old Patients With Fixed Orthodontics | Tehran University of Medical Sciences | Not applicable | Completed | Dental Caries, Bleeding on Probing, Gingival Index, Plaque Index | 72 | Iran | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07667283) |
| June 15, 2026 | NCT07648979 | 3D-Printed Resin Crowns vs Stainless Steel Crowns in Pulpotomized Primary Molars. | Cairo University | Not applicable | Not yet recruiting | Dental Caries | 26 | Egypt | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07648979) |
| June 15, 2026 | NCT07648485 | Clinical Performance of CAD/CAM Hard Hybrid Ceramic Inlays Versus Resin Composite Inlays in Vital Molars With Extensive Occluso-Proximal... | Cairo University | Not applicable | Not yet recruiting | Dental Caries, Cavity, Dental, Proximal Dental Caries | 50 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07648485) |
| June 15, 2026 | NCT07648212 | Artificial Intelligence (AI) for Proximal Caries Detection and Its Impact on Treatment Threshold | University of Michigan | Not applicable | Recruiting | Caries,Dental | 60 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07648212) |
| June 10, 2026 | NCT07640074 | Clinical Performance of Novel Coconut Based Restorative Material. | Pakistan Institute of Medical Sciences | Not applicable | Enrolling by invitation | Carious Lesion, Restoration | 60 | Pakistan | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07640074) |
| June 8, 2026 | NCT07633717 | 3-D Printed Resin Composite Versus Milled Resin Composite and Hybrid Ceramic Onlays: 2-Year Clinical Performance, Microtensile Bond... | Mansoura University | Not applicable | Active not recruiting | Dental Caries | 36 | Egypt | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07633717) |
| May 28, 2026 | NCT07612540 | Retention and Caries Prevention of Giomer Sealant With or Without Diode Laser Pre-treatment: A Randomized Controlled Trial | Cairo University | Not applicable | Not yet recruiting | Dental Caries | 111 | Egypt | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07612540) |
| May 28, 2026 | NCT07611981 | Dental Caries and Oral Hygiene Status in Children With Specific Learning Disabilities | Alanya Alaaddin Keykubat University | Observational | Recruiting | Specific Learning Disabilities, Dental Caries, Oral Hygiene | 70 | Turkey (Türkiye) | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07611981) |
| May 28, 2026 | NCT07611734 | Luting Cements for Prefabricated Zirconia Crown Retention in Primary Anterior Teeth in Children | Murad Alrashidi | Not applicable | Active not recruiting | Dental Caries, Tooth Injuries, Primary Tooth Restoration | 120 | Saudi Arabia | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07611734) |
| May 27, 2026 | NCT07609797 | The Effects of Sodium Fluoride and Chlorhexidine Use on Salivary IL-6 and Matrix Metalloproteinase Levels in Children With Active Caries | Gül Keskin | Not applicable | Recruiting | Dental Caries, Dental Caries in Children | 80 | Turkey (Türkiye) | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07609797) |
| May 27, 2026 | NCT07608471 | QLF and Digital Imaging for Caries Activity Assessment After Orthodontic Treatment | Universidad El Bosque, Bogotá | Observational | Not yet recruiting | Dental Caries, White Spot Lesions, Caries Lesion Activity, Post-Orthodontic Enamel Demineralization | 30 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07608471) |
| May 12, 2026 | NCT07579403 | Fluoride vs Probiotic Toothpaste for Caries Prevention | The Affiliated Hospital of Qingdao University | Phase 4 | Completed | Dental Caries, Child Behavior | 508 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07579403) |
| May 8, 2026 | NCT07574814 | Effect of Self-assembly Peptide With or Without Laser on Remineralization of Initial Carious | Delta University for Science and Technology | Not applicable | Completed | Carious Lesion, Caries; Initial | 30 | Egypt | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07574814) |
| May 1, 2026 | NCT07561216 | Injectable Bioactive Composites vs RMGI for Proximal Cavities in Primary Molars | Cairo University | Not applicable | Not yet recruiting | Dental Caries | 50 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07561216) |
| May 1, 2026 | NCT07560514 | Assessment of Digital Technologies for Detection of Dental Caries | University Hospital, Martin | Not applicable | Recruiting | Dental Caries | 100 | Slovakia | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07560514) |
| April 29, 2026 | NCT07555223 | Intraoral Scan and CBCT-Aided Diagnosis of Dental Plaque and Caries | University Ghent | Observational | Recruiting | Dental Plaque, Dental Caries | 50 | Belgium | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07555223) |
| April 27, 2026 | NCT07552129 | Injectable Bioactive Composite vs Hall Technique for Proximal Cavities in Primary Molars | Cairo University | Not applicable | Not yet recruiting | Dental Caries | 50 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07552129) |
| April 23, 2026 | NCT07548008 | Ferric Sulfate and Sodium Hypochlorite Pulpotomies in Vital Primary Teeth | Marmara University | Observational | Active not recruiting | Dental Caries, Pulpotomies Primary Teeth | 56 | Turkey (Türkiye) | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07548008) |
| April 23, 2026 | NCT07547904 | Clinical Performance of Bioactive Bulk-Fill in Class II Restorations | Bezmialem Vakif University | Not applicable | Recruiting | Dental Caries | 34 | Turkey (Türkiye) | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07547904) |
| April 22, 2026 | NCT07544849 | A Randomized Split-Mouth Clinical Trial Comparing Resin Infiltration and Microabrasion for Early Caries Lesions | Can Tho University of Medicine and Pharmacy | Not applicable | Completed | Dental Caries, Early Caries Lesions, White Spot Lesions\[Initial Caries\]on Smooth Surface of Tooth | 30 | Vietnam | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07544849) |
| April 20, 2026 | NCT07538232 | Oral Microecology in Children With Autism | The Dental Hospital of Zhejiang University School of Medicine | Observational | Completed | Autism, Caries,Dental | 380 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07538232) |
| April 20, 2026 | NCT07538089 | Caries Removal Methods and Microbiome Changes | Nuh Naci Yazgan University | Not applicable | Active not recruiting | Caries, Dental | 48 | Turkey (Türkiye) | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07538089) |
| April 15, 2026 | NCT07532291 | Detection of Non-cavitated Occlusal Caries Lesions by Visual Inspection, LF, QLF and NILT | Neslihan Atmaca | Observational | Completed | Dental Caries, Non-cavitated Occlusal Caries | 51 | Turkey (Türkiye) | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07532291) |
| April 15, 2026 | NCT07530835 | Occlusal Changes After Modified Hall Technique in Molars Affected by Molar-Incisor Hypomineralization | Ankara Yildirim Beyazıt University | Not applicable | Not yet recruiting | Dental Caries, Dental Occlusion, Pediatric Dentistry | 46 | Turkey (Türkiye) | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07530835) |
| April 13, 2026 | NCT07523776 | Vertical Dimension Changes After Bioflx vs Stainless Steel Crowns in Primary Molars | Cairo University | Not applicable | Not yet recruiting | Early Childhood Caries, Dental Caries, Pulp-Treated Primary Molars | 18 | Egypt | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07523776) |
| April 9, 2026 | NCT07519382 | Comparing the Clinical Success of Two Different CAD/CAM Full Cuspal Coverage Onlays | Semmelweis University | Not applicable | Enrolling by invitation | Tooth Decay | 164 | Hungary | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07519382) |
| April 2, 2026 | NCT07507136 | Novel Dental Cements (ALBO-MPCA) in Patients With Caries | Albos d.o.o. Beograd | Not applicable | Completed | Dental Caries | 20 | Bosnia and Herzegovina | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07507136) |
| March 31, 2026 | NCT07504393 | Clinical Performance of Four Restorative Materials in Primary Molars | Al-Azhar University | Not applicable | Not yet recruiting | Dental Caries, Primary Molars | 92 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07504393) |
| March 25, 2026 | NCT07493278 | Er,Cr:YSGG Laser Versus Conventional Preparation for Minimally Invasive Caries Removal | Medical University of Sofia | Not applicable | Completed | Dental Caries | 32 | Bulgaria | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07493278) |
| March 17, 2026 | NCT07476417 | Oral Health, Dento-facial Condition and OHRQoL in Subjects With Mowat-Wilson Syndrome: an Epidemiologic Study. | University of Milan | Observational | Not yet recruiting | Mowat-Wilson Syndrome, Dental Caries, Periodontal Diseases, Sleep Related Breathing Disorder, Tooth Diseases... | 25 | Italy | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07476417) |
| March 13, 2026 | NCT07471360 | Clinical Performance and Immediate Child and Parental Satis-faction With BioFlx Crowns in Primary Molars: A Prospective, Single-Arm... | King Abdulaziz University | Not applicable | Completed | Dental Caries | 28 | Saudi Arabia | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07471360) |
| March 11, 2026 | NCT07465211 | Comparative Evaluation of Clinical Success of BIOFLX Crowns and SSC in Primary Molars | satish vishwanathaiah | Not applicable | Completed | Dental Caries, Restored Decayed Teeth and Post-operative Sensitivity | 36 | India | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07465211) |
| March 3, 2026 | NCT07447583 | Traditional vs. Minimally Invasive Decay Treatments in Primary Molars: An 18-month Split-mouth Randomized Study | TC Erciyes University | Not applicable | Completed | Dental Caries | 60 | Turkey (Türkiye) | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07447583) |
| February 24, 2026 | NCT07431463 | Effects of Different Remineralization Agents on the Progression of Non-Cavitated Approximal Carious Lesions in Primary Teeth: A Randomized... | Izmir Katip Celebi University | Not applicable | Active not recruiting | Dental Caries | 90 | Turkey (Türkiye) | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07431463) |
| February 23, 2026 | NCT07427095 | The Relationship Between Ultra-Processed Food Consumption and Oral Health | Recep Tayyip Erdogan University Training and Research Hospital | Observational | Not yet recruiting | Ultra-processed Food | 200 | Turkey (Türkiye) | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07427095) |
| February 23, 2026 | NCT07427004 | Sleep Problems, Salivary Biomarkers, Dental Caries and Periodontal Status in School-Aged Children | Bezmialem Vakif University | Observational | Completed | Dental Caries, Sleep Problems, Periodontal Status | 73 | Turkey (Türkiye) | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07427004) |
| February 19, 2026 | NCT07421206 | DETERMINATION OF THE EFFECTS OF STAINLESS STEEL CROWNS CEMENTED WITH RESIN CEMENTS ON INTERLEUKIN-10, 12, 18 LEVELS IN GINGIVAL CREVICULAR... | Afyonkarahisar Health Sciences University | Not applicable | Not yet recruiting | Dental Caries, Gingival Inflammation, Periodontal Response to Dental Restorative Materials | 45 | Turkey (Türkiye) | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07421206) |
| February 19, 2026 | NCT07419763 | Intra Oral Appliance (IOA) Model Evaluating the Efficacy of Sensitive Toothpaste | Church & Dwight Company, Inc. | Not applicable | Completed | Dental Caries | 30 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07419763) |
| February 19, 2026 | NCT07419685 | Intraoral Appliance (IOA) Model Evaluating the Efficacy of a Whitening Toothpaste | Church & Dwight Company, Inc. | Not applicable | Completed | Dental Caries | 31 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07419685) |
| February 19, 2026 | NCT07419672 | Intra Oral Application (IOA) Testing Study of a Stannous Toothpaste | Church & Dwight Company, Inc. | Not applicable | Completed | Dental Caries | 31 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07419672) |
| February 17, 2026 | NCT07414030 | Salivary Antimicrobial Peptides and Severe Early Childhood Caries in Turkish Children | Bezmialem Vakif University | Observational | Completed | Severe Early Childhood Caries, Dental Caries | 50 | Turkey (Türkiye) | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07414030) |
| February 13, 2026 | NCT07409610 | Miswak (Salvadora Persica) Versus a Toothbrush in Plaque Removal | King Abdulaziz University | Not applicable | Completed | Dental Caries, Dental Plaque Accumulation | 82 | Saudi Arabia | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07409610) |
| February 12, 2026 | NCT07405437 | General Dentists' Knowledge, Attitudes and Clinical Usage of SDF | University of Edinburgh | Observational | Completed | Decay, Dental | 34 | United Kingdom | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07405437) |
| February 11, 2026 | NCT07404007 | Detection of Proximal Caries in Bitewing Radiography Using Artificial Intelligence | Cairo University | Observational | Completed | Proximal Caries, Tooth Caries | 2,000 | Egypt | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07404007) |

## Sponsors posting most

| Sponsor | New trials | Latest |
| --- | --- | --- |
| Cairo University | 29 | October 29, 2026 |
| Mansoura University | 5 | July 7, 2026 |
| Bezmialem Vakif University | 5 | April 23, 2026 |
| Marmara University | 4 | October 20, 2026 |
| King Abdulaziz University | 4 | August 14, 2026 |
| Hacettepe University | 4 | June 29, 2026 |
| Ankara Yildirim Beyazıt University | 3 | November 4, 2026 |
| University of Jazan | 3 | October 26, 2026 |
| Cumhuriyet University | 3 | September 29, 2026 |
| Colgate Palmolive | 3 | September 8, 2026 |
| Tanta University | 3 | August 26, 2026 |
| Ain Shams University | 3 | July 22, 2026 |
| Al-Azhar University | 3 | March 31, 2026 |
| Church & Dwight Company, Inc. | 3 | February 19, 2026 |
| Ege University | 3 | February 6, 2026 |
| Çanakkale Onsekiz Mart University | 3 | November 25, 2025 |
| Future University in Egypt | 3 | March 28, 2025 |
| Loma Linda University | 2 | October 28, 2026 |
| University of Michigan | 2 | October 5, 2026 |
| October University for Modern Sciences and Arts | 2 | July 24, 2026 |

## By phase

| Phase | New trials | Latest |
| --- | --- | --- |
| [Not applicable](https://specstream.ai/data/clinical-trials/phase/not-applicable) | 153 | November 9, 2026 |
| [Observational](https://specstream.ai/data/clinical-trials/phase/observational) | 50 | November 9, 2026 |
| [Phase 4](https://specstream.ai/data/clinical-trials/phase/phase-4) | 5 | September 8, 2026 |
| [Phase 3](https://specstream.ai/data/clinical-trials/phase/phase-3) | 5 | August 3, 2026 |
| [Phase 2](https://specstream.ai/data/clinical-trials/phase/phase-2) | 4 | October 26, 2026 |
| [Early phase 1](https://specstream.ai/data/clinical-trials/phase/early-phase-1) | 4 | December 24, 2025 |
| [Phase 1/2](https://specstream.ai/data/clinical-trials/phase/phase-1-2) | 1 | October 7, 2026 |
| [Phase 2/3](https://specstream.ai/data/clinical-trials/phase/phase-2-3) | 1 | September 23, 2025 |

## By country

| Country | New trials | Latest |
| --- | --- | --- |
| [Turkey (Türkiye)](https://specstream.ai/data/clinical-trials/country/turkey-t-rkiye) | 52 | November 4, 2026 |
| [Egypt](https://specstream.ai/data/clinical-trials/country/egypt) | 48 | October 19, 2026 |
| [United States](https://specstream.ai/data/clinical-trials/country/united-states) | 21 | October 6, 2026 |
| [Saudi Arabia](https://specstream.ai/data/clinical-trials/country/saudi-arabia) | 9 | October 26, 2026 |
| [Pakistan](https://specstream.ai/data/clinical-trials/country/pakistan) | 5 | October 9, 2026 |
| [Brazil](https://specstream.ai/data/clinical-trials/country/brazil) | 5 | September 10, 2026 |
| [Sweden](https://specstream.ai/data/clinical-trials/country/sweden) | 4 | October 20, 2026 |
| [Vietnam](https://specstream.ai/data/clinical-trials/country/vietnam) | 4 | September 21, 2026 |
| [China](https://specstream.ai/data/clinical-trials/country/china) | 4 | August 4, 2026 |
| [Belgium](https://specstream.ai/data/clinical-trials/country/belgium) | 3 | November 9, 2026 |
| [Malaysia](https://specstream.ai/data/clinical-trials/country/malaysia) | 3 | February 11, 2026 |
| [Switzerland](https://specstream.ai/data/clinical-trials/country/switzerland) | 3 | December 2, 2025 |
| [France](https://specstream.ai/data/clinical-trials/country/france) | 3 | October 3, 2025 |
| [Spain](https://specstream.ai/data/clinical-trials/country/spain) | 2 | November 9, 2026 |
| [Syria](https://specstream.ai/data/clinical-trials/country/syria) | 2 | October 7, 2026 |
| [Chile](https://specstream.ai/data/clinical-trials/country/chile) | 2 | October 7, 2026 |
| [Canada](https://specstream.ai/data/clinical-trials/country/canada) | 2 | June 30, 2026 |
| [Thailand](https://specstream.ai/data/clinical-trials/country/thailand) | 2 | December 24, 2025 |
| Albania | 2 | November 24, 2025 |
| [Jordan](https://specstream.ai/data/clinical-trials/country/jordan) | 2 | August 26, 2025 |
| [Finland](https://specstream.ai/data/clinical-trials/country/finland) | 1 | October 20, 2026 |
| [Slovenia](https://specstream.ai/data/clinical-trials/country/slovenia) | 1 | October 8, 2026 |
| [South Korea](https://specstream.ai/data/clinical-trials/country/south-korea) | 1 | August 6, 2026 |
| [Iran](https://specstream.ai/data/clinical-trials/country/iran) | 1 | June 25, 2026 |
| [Slovakia](https://specstream.ai/data/clinical-trials/country/slovakia) | 1 | May 1, 2026 |

## Where the register publishes

- [ClinicalTrials.gov](https://clinicaltrials.gov/)
- [ClinicalTrials.gov API](https://clinicaltrials.gov/data-api/api)

Source: [ClinicalTrials.gov API v2 (U.S. National Library of Medicine)](https://clinicaltrials.gov/data-api/api). U.S. government data; ClinicalTrials.gov terms of use. Studies are as their sponsors registered them on ClinicalTrials.gov, read through its API. Condition groups are the MeSH terms ClinicalTrials.gov assigns to each study's conditions; a study with several is in several groups. Sponsor class is the register's class of the lead sponsor. The central contact is in the full list only as the record prints it.

Free to reuse with credit to SpecStream under [CC BY 4.0](https://creativecommons.org/licenses/by/4.0/).