# Cognitive Dysfunction trials: 755 new since Nov 2024

Updated November 5, 2026.

755 clinical studies in Cognitive Dysfunction were first posted on ClinicalTrials.gov from November 12, 2024 to November 5, 2026; 69 have an industry sponsor and 493 are recruiting or about to. The newest, NCT07918638, was posted on November 5, 2026: Prospective Research on Identification of Dementia in Early Stages (P.R.I.D.E) (Don Mottola Medical Center).

## The full list

New Cognitive Dysfunction clinical trials: 755 rows for $37.75, first posted on ClinicalTrials.gov from November 12, 2024 to November 9, 2026. Columns: NCT ID, Title, Sponsor, Sponsor class, Phase, Status, Conditions, Condition groups (MeSH), Interventions, Start date, First posted, Enrollment, Enrollment type, Location countries, Central contact, Contact phone, Contact email, Last update posted, Read on, Source. The new rows each week by email, about 32 rows a month: $19 a month. Pay by card with no account. Prices exclude VAT. CSV and Excel files with the columns this page does not show (central contact, contact phone, contact email, sponsor class, condition groups (MeSH), interventions and 5 more), which open on your screen as soon as the payment clears and come by email. The rows on this page are a sample.

Buy: https://specstream.ai/data/clinical-trials/condition/cognitive-dysfunction

SpecStream is the live web data engine for teams and agents. It reads every new study on ClinicalTrials.gov each morning, and this page is that reading. Ask for the conditions, phases or countries you follow and each new trial arrives in your sheet, CRM, Slack or agent with the sponsor, the sites and the listed contact.

- New trials: 755
- Industry sponsored: 69
- Recruiting or not yet: 493
- Latest posted: November 5, 2026

## Newest trials

The newest 100 of 755, each linked to its record. The full list holds every one with the sponsor class, interventions, start date and the central contact as the record prints it.

| First posted | NCT ID | Title | Sponsor | Phase | Status | Conditions | Enrollment | Countries | Source |
| --- | --- | --- | --- | --- | --- | --- | --- | --- | --- |
| November 5, 2026 | NCT07918638 | Prospective Research on Identification of Dementia in Early Stages (P.R.I.D.E) | Don Mottola Medical Center | Observational | Not yet recruiting | Mild Cognitive Impairment, Memory Disorders, Dementia | 1,000 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07918638) |
| November 4, 2026 | NCT07917182 | Chinese University-Alzheimer's Disease With Vascular and Other Co-pathology: Towards Actionable Neuro-Cognitive-Omic Evaluations... | Chinese University of Hong Kong | Observational | Not yet recruiting | Alzheimer s Disease, Mild Cognitive Impairment (MCI) | 1,600 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07917182) |
| November 4, 2026 | NCT07915583 | The Effects of Fine Motor Training With Augmented Reality on the Memory of Older Adults With Amnestic Mild Cognitive Impairment | National Cheng-Kung University Hospital | Not applicable | Completed | Healthy Elderly, Mild Cognitive Impairment (MCI) | 28 | Taiwan | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07915583) |
| November 3, 2026 | NCT07914218 | Rural Veteran and Care Partner Walking Program | Creighton University | Not applicable | Recruiting | Mild Cognitive Impairment (MCI) | 12 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07914218) |
| November 3, 2026 | NCT07913243 | Small Monetary Incentives for Digital Cognitive Training Adherence in Community-Dwelling Older Adults | Xuanwu Hospital, Beijing | Not applicable | Not yet recruiting | Cognitive Decline, Dementia Prevention | 110 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07913243) |
| November 3, 2026 | NCT07912775 | Transcranial Direct Current Stimulation for Chemotherapy-Related Chronic Pain in Cancer Survivors | Instituto de investigación e innovación biomédica de Cádiz | Not applicable | Not yet recruiting | Chronic Pain, Neuropathic Pain, Cancer Survivors, Anxiety, Depression, Cognitive Dysfunction, Chemotherapy-Related... | 60 | Spain | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07912775) |
| November 3, 2026 | NCT07912736 | BioMIND Biospecimen Repository | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | Observational | Enrolling by invitation | Alzheimer's Disease (AD), Cognitive Impairment | 1,000 | Canada | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07912736) |
| November 3, 2026 | NCT07912710 | China HEalthy Aging and Dementia Study (HEAD) | Fudan University | Observational | Recruiting | Alzheimer Disease (AD), Mild Cognitive Impairment (MCI), Dementia, Vascular Dementia (VaD), Cognitive Decline, Familial... | 20,000 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07912710) |
| November 2, 2026 | NCT07910994 | A Prospective Study of Cognitive Changes in Retired and Late-Career Professional Soccer Players | University Hospital, Strasbourg, France | Observational | Not yet recruiting | Cognitive Impairment, Chronic Traumatic Encephalopathy (CTE) | 75 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07910994) |
| October 27, 2026 | NCT07897916 | Detecting and Predicting Post-stroke Cognitive Impairment Using the Oxford Cognitive Screen | University of Copenhagen | Observational | Not yet recruiting | Stroke, Ischemic Stroke, Hemorrhagic Stroke, Intracerebral, Cognitive Dysfunction, Post-Stroke Cognitive Impairment... | 180 | Denmark | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07897916) |
| October 27, 2026 | NCT07897474 | EEG Markers From Polysomnography and Cognitive Performance in Obstructive Sleep Apnea | University of Split, School of Medicine | Observational | Not yet recruiting | Obstructive Sleep Apnea, Cognitive Impairment | 100 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07897474) |
| October 26, 2026 | NCT07894107 | Development and Validation of Risk Prediction Models for Stroke and Cognitive Impairment in Moyamoya Disease and Moyamoya Syndrome | Beijing Tiantan Hospital | Observational | Recruiting | Moyamoya Disease, Moyamoya Syndrome | 3,000 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07894107) |
| October 23, 2026 | NCT07891429 | Fuzhou Aging Brain Health Initiative | Fujian Medical University Union Hospital | Observational | Recruiting | Dementia, Alzheimer Dementia (AD), Mild Cognitive Impairment (MCI), Subjective Cognitive Decline (SCD) | 3,000 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07891429) |
| October 21, 2026 | NCT07887776 | Physical Performance and Cognitive Functions in Patients With Chronic Stroke | Kutahya Health Sciences University | Observational | Completed | Stroke | 66 | Turkey (Türkiye) | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07887776) |
| October 21, 2026 | NCT07887737 | Deep Brain Stimulation Guided by Brain Mapping to Treat Cognitive Impairment | University of Texas Southwestern Medical Center | Not applicable | Not yet recruiting | Mild Cognitive Impairment (MCI), Mild Cognitive Impairment (MCI) Amnestic, Mild Cognitive Impairment (MCI) Due to... | 6 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07887737) |
| October 21, 2026 | NCT07885085 | Postsurgical Pain and Opioid Use in Older Adults: Effects of Mild Cognitive Impairment | Miklos Kertai | Observational | Not yet recruiting | Mild Cognitive Impairment (MCI), Opioid Use, Cognitive Dysfunction, Postoperative Pain | 552 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07885085) |
| October 20, 2026 | NCT07883746 | Remote Digital Assessments for Cognitive Disorders | Centre for Addiction and Mental Health | Observational | Not yet recruiting | Mild Cognitive Impairment (MCI), Alzheimer Disease (AD) | 60 | Canada | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07883746) |
| October 20, 2026 | NCT07883720 | EXercise-induced PhysioLogical Adaptations In Neurological Disorders | Brigham and Women's Hospital | Not applicable | Recruiting | Epilepsy, Functional Neurological Disorder, Mild Cognitive Impairment, Dementia, Parkinson Disease, Concussion, Brain... | 240 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07883720) |
| October 20, 2026 | NCT07883148 | TPSAlz - Transcranial Pulse Stimulation in Alzheimer's Disease | IRCCS San Raffaele Roma | Not applicable | Completed | Alzheimer Disease, Mild Cognitive Impairment | 52 | Italy | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07883148) |
| October 20, 2026 | NCT07882901 | Effects of Tadalafil on Cognition and Cerebral Hemodynamics in Elderly Patients With Mild Cognitive Impairment | Los Angeles Brain Science Project | Phase 2 | Not yet recruiting | Mild Cognitive Impairment (MCI) | 44 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07882901) |
| October 20, 2026 | NCT07882875 | Clinical Significance of Internal Carotid Artery Dolichoarteriopathy | Kuban State Medical University | Observational | Not yet recruiting | Internal Carotid Artery Dolichoarteriopathy, Carotid Artery Tortuosity | 560 | Russia | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07882875) |
| October 19, 2026 | NCT07881029 | Cognitive Impairment and Return to Work in Long COVID | Hopitaux de Saint-Maurice | Observational | Completed | Long COVID | 55 | France | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07881029) |
| October 16, 2026 | NCT07877376 | Impact of Cognitive Impairment on Chronic Pain in Breast Cancer | Nadine ATTAL | Observational | Recruiting | Breast Cancer | 182 | France | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07877376) |
| October 15, 2026 | NCT07876570 | A Prospective Cohort Study of Multimodal Biomarkers and Progression From Mild Cognitive Impairment to Dementia | Xuanwu Hospital, Beijing | Observational | Recruiting | Mild Cognitive Impairment (MCI) | 600 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07876570) |
| October 15, 2026 | NCT07876271 | PICS-p Longitudinal Cohort Study | Children's Hospital of Fudan University | Observational | Not yet recruiting | Physical Functional Impairment, Cognitive Impairment, Psychological Distress, Impaired Social Functioning | 200 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07876271) |
| October 15, 2026 | NCT07874685 | Mindfulness-Integrated Neuropsychotherapy for Traumatic Brain Injury: A Mixed-Methods Evaluation of Cognitive and Psychosocial Recovery | University of Madras | Not applicable | Completed | Traumatic Brain Injury (TBI) Patients, Cognitive Impairment, Depression Disorder, Fatigue Severity Scale, Quality of... | 68 | India | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07874685) |
| October 14, 2026 | NCT07873463 | Flutemetamol F 18 Injection Formulation Comparison | GE Healthcare | Phase 2 | Recruiting | Cognitive Dysfunction | 20 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07873463) |
| October 13, 2026 | NCT07872189 | Dyadic Cognitive Intervention for Older Adults With Cognitive Impairment and Their Spouses | Gansu University of Chinese Medicine | Not applicable | Not yet recruiting | Cognitive Impairment | 136 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07872189) |
| October 13, 2026 | NCT07871487 | Tau Pathology in the Brain After Hip or Knee Replacement Surgery | Uppsala University Hospital | Observational | Recruiting | Postoperative Cognitive Dysfunction, Alzheimer Disease, Tauopathies, Neuroinflammation, Arthroplasty, Replacement, Hip... | 30 | Sweden | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07871487) |
| October 13, 2026 | NCT07870291 | Effectiveness of a Multimodal Cognitive Rehabilitation Protocol Combined With Mechanical Periodontal Therapy in Diabetic Patients With... | Emad Eldin Mohamed | Not applicable | Active not recruiting | Diabete Mellitus | 105 | Egypt | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07870291) |
| October 13, 2026 | NCT07869745 | Auditory-Cognitive Optimization Care Program for Older Adults With Hearing Loss and Cognitive Impairment | Taipei Medical University | Not applicable | Not yet recruiting | Hearing Loss, Cognitive Impairment | 76 | Taiwan | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07869745) |
| October 8, 2026 | NCT07866768 | CMN LIFU for Enhanced Amyloid Reduction (CLEART Study) | University of California, San Francisco | Not applicable | Recruiting | Alzheimer's Disease (AD), Mild Cognitive Impairment (MCI), Mild Cognitive Impairment (MCI) Due to Alzheimer's Disease | 28 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07866768) |
| October 8, 2026 | NCT07865260 | PhiCube for Bilateral Upper Limb Neuromotor and Cognitive Rehabilitation in Adults | Istituto di Sistemi e Tecnologie Industriali Intelligenti per il Manifatturiero Avanzato | Not applicable | Not yet recruiting | Stroke, Parkinson Disease, Amyotrophic Lateral Sclerosis, Spinal Cord Injuries, Mild Cognitive Impairment, Upper... | 80 | Italy | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07865260) |
| October 7, 2026 | NCT07863518 | Transcranial Direct Current Stimulation Combined With Tai Chi for Dual-Task Mobility and Cognitive Function in Older Adults With Cognitive... | Shanghai University of Sport | Not applicable | Completed | Mild Cognitive Impairment (MCI), Self-Reported Memory Concerns | 61 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07863518) |
| October 5, 2026 | NCT07859540 | Negotiation Training for Family Caregivers of People With Alzheimer's Disease | Northwestern University | Not applicable | Not yet recruiting | Alzheimer's Disease (AD), Dementia, Cognitive Impairment | 200 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07859540) |
| October 2, 2026 | NCT07856381 | Understanding Lifespan Trajectories of Social Cognition, Brain Microstructure and Iron Dysregulation in Schizophrenia | Medical University Innsbruck | Observational | Recruiting | Healthy Control Subjects, Schizophrenia Diagnosis | 180 | Austria | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07856381) |
| October 2, 2026 | NCT07856043 | \[11C\]PS13 PET Imaging of Neuroinflammation in Heart Failure With Reduced Ejection Fraction | Stony Brook University | Phase 1 | Not yet recruiting | Heart Failure With Reduced Ejection Fraction, Cognitive Impairment, Mild, Neuroinflammation, Vascular Contributions to... | 18 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07856043) |
| October 2, 2026 | NCT07854444 | Beta-1 Band Functional Connectivity Mediates the Effects of Acute Exercise on Cognitive Flexibility in Older Adults With Cognitive... | Shanghai University of Sport | Not applicable | Not yet recruiting | Cognitive Impairment, Cognitive Flexibility, Brain Functional Connectivity | 60 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07854444) |
| October 1, 2026 | NCT07852650 | Digital STEADI Efficacy | Friendi.fi Corporation | Phase 1/2 | Recruiting | Fall, Mild Cognitive Impairment (MCI), Aging | 300 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07852650) |
| October 1, 2026 | NCT07852052 | Sleep Architecture, Cognitive Function, and Quality of Life During Early Recovery From Substance Use Disorder | Assiut University | Observational | Not yet recruiting | Substance-Related Disorders, Substance Use Disorder, Sleep Wake Disorders, Cognitive Dysfunction | 34 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07852052) |
| September 29, 2026 | NCT07846566 | Choose Myself (Before) Losing Myself | The Cleveland Clinic | Not applicable | Recruiting | Dementia (Diagnosis), Mild Cognitive Impairment, Alzheimer's Disease Dementia, Alzheimer's Disease | 25 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07846566) |
| September 28, 2026 | NCT07844850 | Biomarkers as Prognostic Factors of Silent, Cerebral Infarctions in Patients Undergoing High-thromboembolic-risk Transcatheter Interventions | Aristotle University Of Thessaloniki | Observational | Recruiting | Silent Cerebral Infarct, Biomarkers / Blood, Cardiac Ablation, Cognitive Impairment | 100 | Greece | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07844850) |
| September 25, 2026 | NCT07842679 | Cognitive Impairment in Older Adults With Hematologic Malignancies | Assiut University | Observational | Not yet recruiting | Cognitive Impairment, Hematologic Malignancies, Chemotherapy Effect | 120 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07842679) |
| September 25, 2026 | NCT07842029 | Evaluation of Blood-Based Biomarkers and Remote Cognitive Assessment for Dementia Triage (SANDBOX) | Prima Mente | Observational | Recruiting | Dementia, Cognitive Impairment | 1,000 | United Kingdom | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07842029) |
| September 24, 2026 | NCT07839286 | Jigsawdio Multisensory Platform for People With Mild Cognitive Impairment, Alzheimer's Disease, or Related Dementias | Callahan-Young LLC DBA Jigsawdio | Not applicable | Not yet recruiting | Alzheimer Disease, Dementia, Mild Cognitive Impairment | 80 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07839286) |
| September 24, 2026 | NCT07838909 | Intraoperative Ketamine Versus Lidocaine Infusion on Postoperative Cognitive Dysfunction in Patients Undergoing Hip Surgery | Tanta University | Not applicable | Completed | Ketamine, Cognitive, Dysfunction, Hip Surgeries | 120 | Egypt | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07838909) |
| September 23, 2026 | NCT07837258 | Serum Sulfate and Brain Function in Diabetic Encephalopathy | Dongzhimen Hospital, Beijing | Observational | Not yet recruiting | Diabetes Mellitus, Type 2, Cognitive Dysfunction, Cognitive Disorder, Brain Diseases, Metabolic | 220 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07837258) |
| September 23, 2026 | NCT07836114 | Virtual Outreach and Individualized Coaching Extension | Emory University | Not applicable | Not yet recruiting | Chronic Disease, Mild Cognitive Impairment | 50 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07836114) |
| September 23, 2026 | NCT07835568 | Thrive at Home: A Virtual Reality Social Intervention for Older Adults | University of California, Santa Barbara | Not applicable | Not yet recruiting | Mental Health (Depression), Mental Health and General Well-being, Loneliness, Well Being, Caregiver Burden, Caregiver... | 250 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07835568) |
| September 22, 2026 | NCT07835399 | Efficacy and Safety of Photobiomodulation Therapy in Patients With Mild Cognitive Impairment and Mild Alzheimer's Disease | Jun Xu | Not applicable | Recruiting | Mild Cognitive Impairment (MCI), Mild Alzheimer Disease, Dementia | 20 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07835399) |
| September 22, 2026 | NCT07834528 | Brain Heath Service for Prevention of AD | Chinese University of Hong Kong | Not applicable | Enrolling by invitation | Alzheimer, Cognitive Unimpaired, Mild Cognitive Impairment | 4,000 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07834528) |
| September 22, 2026 | NCT07833644 | The Effect of Telerehabilitation Based Physical Activity Training Associated With Single and Dual Task Training on Physical and Cognitive... | Pamukkale University | Not applicable | Active not recruiting | Primer Sjogren's Syndrome | 36 | Turkey (Türkiye) | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07833644) |
| September 22, 2026 | NCT07833267 | Cognition and Affective Research in China | Xuanwu Hospital, Beijing | Observational | Not yet recruiting | Neurodegenerative Disease, Dementia, Alzheimer's Disease, Parkinson's Disease, Mood Disorders, Depression, Anxiety... | 3,000 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07833267) |
| September 21, 2026 | NCT07831850 | Nurse-Led Active Music Program in Older Adults With Cognitive Impairment | Universidad de Almeria | Not applicable | Completed | Cognitive Impairment | 11 | Spain | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07831850) |
| September 21, 2026 | NCT07829380 | The Cardiovascular-Cognitive Health Initiative | National Heart Centre Singapore | Not applicable | Recruiting | Cognitive Impairment | 5,000 | Singapore | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07829380) |
| September 18, 2026 | NCT07827963 | VisMemoPD Protocol: an Observational Pilot Study on Spatial and Topographical Memory in Patients With Parkinson's Disease and Parkinsonism | IRCCS San Raffaele Roma | Observational | Not yet recruiting | Parkinson's Disease, Parkinsonism, Multiple System Atrophy, Progressive Supranuclear Palsy, Mild Cognitive Impairment | 80 | Italy | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07827963) |
| September 17, 2026 | NCT07825909 | Virtual Reality-Assisted Reminiscence Therapy in Older Adults With Cognitive Impairment | Istituto Universitario Salesiano Venezia-Mestre (IUS) | Not applicable | Completed | Cognitive Impairment | 60 | Italy | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07825909) |
| September 17, 2026 | NCT07825636 | Sensorimotor Function in COPD | Alanya Alaaddin Keykubat University | Observational | Completed | Chronic Obstructive Pulmonary Disease (COPD) | 95 | Turkey (Türkiye) | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07825636) |
| September 17, 2026 | NCT07824128 | Adaptango Performance PRocess for Older Adults Community reHabilitation | Emory University | Not applicable | Not yet recruiting | Parkinson Disease, Mild Cognitive Impairment, Old Age; Dementia | 120 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07824128) |
| September 16, 2026 | NCT07822867 | Effects of an Exercise Snacking Intervention on Cognitive Function in Patients With Mild Cognitive Impairment: A Nationwide Multicenter... | Peking University | Not applicable | Not yet recruiting | Mild Cognitive Impairment | 240 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07822867) |
| September 14, 2026 | NCT07818369 | Synbiotic LA-5 and Agave Inulin for Mild Cognitive Impairment | Anahuac University | Not applicable | Recruiting | Cognitive Impairment | 20 | Mexico | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07818369) |
| September 10, 2026 | NCT07812480 | Multimodal Biomarkers in Individual With Cognitive Impairment and Dementia | Assiut University | Observational | Not yet recruiting | Dementia Disorders, Mild Cognitive Impairment (MCI) | 75 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07812480) |
| September 9, 2026 | NCT07808619 | Longevity Metrics AI/ML Development Study | Longevity Metrics, Inc. | Observational | Recruiting | Aging, Mortality, Cardiovascular Disease Prevention, Metabolic Syndrome, Cognitive Dysfunction, Frailty... | 1,000,000 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07808619) |
| September 8, 2026 | NCT07806877 | Efficacy and Safety of Individualized Sequential Accelerated Theta Burst Stimulation in Improving Cognitive Function in Schizophrenia | Central South University | Not applicable | Not yet recruiting | Schizophrenia / Schizoaffective Disorder, TMS, Cognitive, PET / MR | 60 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07806877) |
| September 4, 2026 | NCT07804498 | CITADEL: Effectiveness of CITicoline in Preventing Cognitive Decline After DELirium | University of Milano Bicocca | Phase 2 | Recruiting | Cognitive Decline, Delirium | 122 | Italy | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07804498) |
| September 3, 2026 | NCT07803419 | Endovascular Treatment for Symptomatic Non-acute Carotid Occlusion | Dapeng Mo | Not applicable | Not yet recruiting | Non-acute Carotid Artery Occlusion, Cognitive Impairment | 180 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07803419) |
| September 3, 2026 | NCT07803055 | Longitudinal Profiling of Plasma-Derived Glial Extracellular Vesicles in Alzheimer's Disease | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | Not applicable | Recruiting | Subjective Cognitive Decline (SCD), Mild Cognitive Impairment (MCI) Due to Alzheimer's Disease, Alzheimer's Disease... | 48 | Italy | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07803055) |
| September 3, 2026 | NCT07802392 | Immersive Nature-Based Wellbeing Program in Older Adults With Cognitive Impairment | Consorci Sanitari de Terrassa | Not applicable | Recruiting | Cognitive Dysfunction | 230 | Spain | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07802392) |
| September 2, 2026 | NCT07799584 | Temporal Interference Stimulation Combined With Tai Chi for Mild Cognitive Impairment | Shanghai University of Sport | Not applicable | Recruiting | Mild Cognitive Impairment (MCI) | 120 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07799584) |
| September 2, 2026 | NCT07799402 | Microbiome in Aging of Gut and Brain | University of South Florida | Observational | Recruiting | Mild Cognitive Impairment, Alzheimer Disease (AD), Dementia | 700 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07799402) |
| August 31, 2026 | NCT07794956 | LpD3.5 Intervention Study in Older Adults- LISA-I Trial | University of South Florida | Early phase 1 | Recruiting | Mild Cognitive Impairment (MCI), Cognition, Brain Aging, Microbiome Dysbiosis, Leaky Gut Syndrome, Gut Inflammation... | 15 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07794956) |
| August 28, 2026 | NCT07793682 | Early Neuropsychological Rehabilitation and Family Psychoeducation After Ischemic Stroke | Althaia Xarxa Assistencial Universitària de Manresa | Not applicable | Active not recruiting | Ischemic Stroke, Cognitive Impairment, Quality of Life, Caregiver Burden | 81 | Spain | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07793682) |
| August 26, 2026 | NCT07788755 | NEURO-COGS: Neurometabolic Mechanisms of Cognitive Training in Schizophrenia | University of Minnesota | Not applicable | Not yet recruiting | Schizophrenia, Schizoaffective Disorder, Cognitive Impairment, Visual Impairment | 168 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07788755) |
| August 26, 2026 | NCT07788209 | Scaffolding in AI-Empowered Cognitive Training Improves Outcomes in Cognitive Impairment | Xuanwu Hospital, Beijing | Observational | Active not recruiting | Cognitive Impairment | 516 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07788209) |
| August 25, 2026 | NCT07786116 | The Role of METhanogens in the PROgression Of Parkinson's Disease and Related Neurological Conditions | University of Cambridge | Not applicable | Recruiting | PARKINSON DISEASE (Disorder), Parkinson, Parkinson Disease, Parkinson s Disease, REM Behavior Disorder, REM Sleep... | 215 | United Kingdom | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07786116) |
| August 25, 2026 | NCT07785648 | Mindfulness-Based Cognitive Therapy Vs. the Health Enhancement Program for Chronic Pain and Early Cognitive Decline; The Feeling of Being... | Massachusetts General Hospital | Not applicable | Not yet recruiting | Chronic Pain, Mild Cognitive Impairment | 60 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07785648) |
| August 25, 2026 | NCT07784946 | A Behavioural Sleep Intervention for People With Mild Cognitive Impairment and Mild Dementia | The Hong Kong Polytechnic University | Not applicable | Recruiting | Mild Cognitive Impairment, Dementia, Sleep | 60 | Hong Kong | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07784946) |
| August 21, 2026 | NCT07780162 | Wearable Sensor for Early Detection and Monitoring of Cognitive Decline | BioSensics | Observational | Not yet recruiting | Mild Cognitive Impairment (MCI), Older Adults With Cognitive Decline, Older Adults | 100 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07780162) |
| August 20, 2026 | NCT07775079 | Comparative Effects of Integrated Versus Sequential Approaches to Dual-Task Training in Elderly With Mild to Moderate Cognitive Impairment | Shifa Tameer-e-Millat University | Not applicable | Recruiting | Mild Cognitive Impairment (MCI), Moderate Cognitive Impairment | 96 | Pakistan | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07775079) |
| August 19, 2026 | NCT07773493 | A Mobile Informatics Solution to Assist Caregivers in Care Coordination and Monitoring Social Engagement | University of Minnesota | Not applicable | Not yet recruiting | Memory Disorders, Mild Cognitive Impairment, Dementia, Social Isolation, Caregiver Burden | 200 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07773493) |
| August 19, 2026 | NCT07772947 | Effects of Hyperbaric Oxygen Combined With Aerobic Exercise on Working Memory Among Stroke Patients | Sixth Hospital of Wuhan, Affiliated Hospital of Jianghan University | Not applicable | Completed | Stroke, Cognitive Impairment | 50 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07772947) |
| August 18, 2026 | NCT07771036 | Hippocampal Temporal Interference Stimulation for Memory and Dual-Task Postural Control in Older Adults With Mild Cognitive Impairment | Shanghai University of Sport | Not applicable | Recruiting | Mild Cognitive Impairment (MCI) | 21 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07771036) |
| August 17, 2026 | NCT07767214 | Efficacy of Vitamin D in Post-Stroke Cognitive Impairment | Suzhou Municipal Hospital of Anhui Province | Not applicable | Active not recruiting | Post-Stroke Cognitive Impairment (PSCI) | 300 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07767214) |
| August 14, 2026 | NCT07764679 | A Clinical Study Evaluating the Diagnostic Performance and Safety of PET for the Deposition of Aβ Plaques in the Brain of Participants With... | HTA Co., Ltd. | Phase 3 | Recruiting | Mild Cognitive Impairment (MCI), Alzheimer's Disease (AD) | 400 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07764679) |
| August 13, 2026 | NCT07764250 | Comparative Evaluation of Immediate vs Progressive Standing Dual Task Training in Elderly With Mild and Moderate Cognitive Impairment | Shifa Tameer-e-Millat University | Not applicable | Recruiting | Cognitive Impairment, Cognitive Impairment, Mild, Moderate Cognitive Impairment | 96 | Pakistan | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07764250) |
| August 13, 2026 | NCT07762235 | High-Amplitude Functional Exercises in Older Adults With Mild Cognitive Impairment | Istinye University | Not applicable | Not yet recruiting | Mild Cognitive Impairment (MCI), Exercises | 36 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07762235) |
| August 12, 2026 | NCT07760545 | Reliability In Neurocognitive Telemedicine Screening (RING) | University of British Columbia | Observational | Recruiting | Cognitive Impairment, Preoperative Cognitive Impairment, Perioperative Neurocognitive Disorders, Neurocognitive... | 300 | Canada | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07760545) |
| August 12, 2026 | NCT07760415 | EEG Changes and Cognitive Profiles in Sepsis Patients With Different Inflammatory Phenotypes | Xiangya Hospital of Central South University | Observational | Not yet recruiting | Sepsis, Sepsis Associated Encephalopathy, Sepsis and Septic Shock, Sepsis at Intensive Care Unit | 78 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07760415) |
| August 11, 2026 | NCT07758751 | Multisensory 40-Hz Stimulation for Alzheimer's Disease | Beijing Tiantan Hospital | Not applicable | Not yet recruiting | Alzheimer Disease | 60 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07758751) |
| August 11, 2026 | NCT07758660 | Alzheimer's Disease Research Center (ADRC) PET Component Study | Patrick Lao | Phase 2 | Enrolling by invitation | Alzheimer Disease, Mild Cognitive Impairment (MCI), Dementia | 120 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07758660) |
| August 11, 2026 | NCT07757555 | Guanfacine and Cromolyn Sodium for POTS: The DBPOTS Trial | Johns Hopkins University | Early phase 1 | Not yet recruiting | Postural Orthostatic Tachycardia Syndrome (POTS), Dysautonomia, Orthostatic Intolerance, Autonomic Nervous System... | 25 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07757555) |
| August 11, 2026 | NCT07757542 | Safety Assessment of H2 Inhalation in Patients With Mild Cognitive Impairment | University of Ostrava | Phase 2 | Recruiting | Mild Cognitive Impairment (MCI) | 34 | Czechia | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07757542) |
| August 10, 2026 | NCT07756294 | Restoring Vascular and Insulin Function To Augment Anti-Amyloid Therapy in Alzheimer's Disease | Wake Forest University Health Sciences | Phase 2 | Not yet recruiting | Alzheimer Disease | 30 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07756294) |
| August 10, 2026 | NCT07755631 | The BASIC-S Feasibility Study for Vascular Risk Reduction | Andrew Appleton | Not applicable | Not yet recruiting | Hypertension (HTN), Vascular Diseases, Stroke, Dementia, Cardiovascular Risk Factor, Cognitive Decline | 120 | Canada | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07755631) |
| August 10, 2026 | NCT07754994 | Medication Self-Management Technology for Older Adults | University of Illinois at Urbana-Champaign | Not applicable | Not yet recruiting | Mild Cognitive Impairment (MCI) | 40 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07754994) |
| August 7, 2026 | NCT07753382 | Effects of Adaptive Difficulty Computerized Cognitive Training on Cognitive Function Improvement in Older Adults With Mild Cognitive... | China Medical University, China | Not applicable | Not yet recruiting | Cognitive Dysfunction, Cognitive Disorder, Cognitive Training | 36 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07753382) |
| August 7, 2026 | NCT07752316 | Gamma tACS to Improve Cognitive Function in Mild Cognitive Impairment | The National Brain Mapping Laboratory (NBML) | Not applicable | Completed | Mild Cognitive Impairment (MCI) | 30 | Iran | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07752316) |
| August 6, 2026 | NCT07750223 | Cognitive Effects of Hesperidin in Overweight/Obese Older Adults | Min Hou | Not applicable | Recruiting | Cognitive Dysfunction, Overweight and Obesity | 105 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07750223) |
| August 5, 2026 | NCT07747675 | Cognitive Intervention for Cognitive Impairment | Instituto Mexicano del Seguro Social | Not applicable | Not yet recruiting | Cognitive Intervention, Mild Cognitive Impairment, Elderly Adults, Diabetes Mellitus | 102 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07747675) |
| August 4, 2026 | NCT07743658 | Explainable AI in Medical Education: CerViD-MultiModal Framework Trial | University of Liberia | Not applicable | Completed | Medical Education | 120 | Liberia | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07743658) |

## Sponsors posting most

| Sponsor | New trials | Latest |
| --- | --- | --- |
| Riphah International University | 11 | July 28, 2026 |
| Xuanwu Hospital, Beijing | 9 | November 3, 2026 |
| The Hong Kong Polytechnic University | 9 | August 25, 2026 |
| Shanghai University of Sport | 7 | October 7, 2026 |
| Massachusetts General Hospital | 7 | August 25, 2026 |
| Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 6 | September 3, 2026 |
| Johns Hopkins University | 6 | August 11, 2026 |
| Fondazione Don Carlo Gnocchi ETS | 6 | July 28, 2026 |
| Chinese University of Hong Kong | 5 | November 4, 2026 |
| Beijing Tiantan Hospital | 5 | October 26, 2026 |
| University of California, San Francisco | 5 | October 8, 2026 |
| IRCCS San Raffaele | 5 | July 21, 2026 |
| IRCCS Centro Neurolesi Bonino Pulejo | 5 | May 5, 2026 |
| Assiut University | 4 | October 1, 2026 |
| Aristotle University Of Thessaloniki | 4 | September 28, 2026 |
| Emory University | 4 | September 23, 2026 |
| Central South University | 4 | September 8, 2026 |
| Medical University of South Carolina | 4 | August 3, 2026 |
| Icahn School of Medicine at Mount Sinai | 4 | May 20, 2026 |
| VA Office of Research and Development | 4 | April 2, 2026 |

## By phase

| Phase | New trials | Latest |
| --- | --- | --- |
| [Not applicable](https://specstream.ai/data/clinical-trials/phase/not-applicable) | 473 | November 4, 2026 |
| [Observational](https://specstream.ai/data/clinical-trials/phase/observational) | 192 | November 5, 2026 |
| [Phase 2](https://specstream.ai/data/clinical-trials/phase/phase-2) | 39 | October 20, 2026 |
| [Phase 3](https://specstream.ai/data/clinical-trials/phase/phase-3) | 14 | August 14, 2026 |
| [Phase 1](https://specstream.ai/data/clinical-trials/phase/phase-1) | 12 | October 2, 2026 |
| [Phase 4](https://specstream.ai/data/clinical-trials/phase/phase-4) | 11 | July 17, 2026 |
| [Phase 1/2](https://specstream.ai/data/clinical-trials/phase/phase-1-2) | 8 | October 1, 2026 |
| [Early phase 1](https://specstream.ai/data/clinical-trials/phase/early-phase-1) | 5 | August 31, 2026 |
| [Phase 2/3](https://specstream.ai/data/clinical-trials/phase/phase-2-3) | 1 | December 16, 2025 |

## By country

| Country | New trials | Latest |
| --- | --- | --- |
| [United States](https://specstream.ai/data/clinical-trials/country/united-states) | 181 | November 3, 2026 |
| [China](https://specstream.ai/data/clinical-trials/country/china) | 104 | November 4, 2026 |
| [Italy](https://specstream.ai/data/clinical-trials/country/italy) | 61 | October 20, 2026 |
| [Turkey (Türkiye)](https://specstream.ai/data/clinical-trials/country/turkey-t-rkiye) | 37 | October 21, 2026 |
| [Spain](https://specstream.ai/data/clinical-trials/country/spain) | 36 | November 3, 2026 |
| [Canada](https://specstream.ai/data/clinical-trials/country/canada) | 31 | November 3, 2026 |
| [Taiwan](https://specstream.ai/data/clinical-trials/country/taiwan) | 25 | November 4, 2026 |
| [France](https://specstream.ai/data/clinical-trials/country/france) | 25 | October 19, 2026 |
| [United Kingdom](https://specstream.ai/data/clinical-trials/country/united-kingdom) | 19 | September 25, 2026 |
| [Pakistan](https://specstream.ai/data/clinical-trials/country/pakistan) | 19 | August 20, 2026 |
| [Hong Kong](https://specstream.ai/data/clinical-trials/country/hong-kong) | 18 | August 25, 2026 |
| [Germany](https://specstream.ai/data/clinical-trials/country/germany) | 17 | April 1, 2026 |
| [South Korea](https://specstream.ai/data/clinical-trials/country/south-korea) | 16 | May 15, 2026 |
| [Poland](https://specstream.ai/data/clinical-trials/country/poland) | 14 | May 20, 2026 |
| [Greece](https://specstream.ai/data/clinical-trials/country/greece) | 13 | September 28, 2026 |
| [Czechia](https://specstream.ai/data/clinical-trials/country/czechia) | 12 | August 11, 2026 |
| [Portugal](https://specstream.ai/data/clinical-trials/country/portugal) | 12 | July 29, 2026 |
| [Denmark](https://specstream.ai/data/clinical-trials/country/denmark) | 11 | October 27, 2026 |
| [Brazil](https://specstream.ai/data/clinical-trials/country/brazil) | 11 | July 28, 2026 |
| [Switzerland](https://specstream.ai/data/clinical-trials/country/switzerland) | 10 | July 22, 2026 |
| [Netherlands](https://specstream.ai/data/clinical-trials/country/netherlands) | 10 | February 19, 2026 |
| [Singapore](https://specstream.ai/data/clinical-trials/country/singapore) | 9 | September 21, 2026 |
| [Egypt](https://specstream.ai/data/clinical-trials/country/egypt) | 7 | October 13, 2026 |
| [Australia](https://specstream.ai/data/clinical-trials/country/australia) | 7 | May 20, 2026 |
| [Argentina](https://specstream.ai/data/clinical-trials/country/argentina) | 7 | September 17, 2025 |

## Where the register publishes

- [ClinicalTrials.gov](https://clinicaltrials.gov/)
- [ClinicalTrials.gov API](https://clinicaltrials.gov/data-api/api)

Source: [ClinicalTrials.gov API v2 (U.S. National Library of Medicine)](https://clinicaltrials.gov/data-api/api). U.S. government data; ClinicalTrials.gov terms of use. Studies are as their sponsors registered them on ClinicalTrials.gov, read through its API. Condition groups are the MeSH terms ClinicalTrials.gov assigns to each study's conditions; a study with several is in several groups. Sponsor class is the register's class of the lead sponsor. The central contact is in the full list only as the record prints it.

Free to reuse with credit to SpecStream under [CC BY 4.0](https://creativecommons.org/licenses/by/4.0/).