# Bipolar Disorder trials: 165 new since Nov 2024

Updated November 6, 2026.

165 clinical studies in Bipolar Disorder were first posted on ClinicalTrials.gov from November 13, 2024 to November 6, 2026; 18 have an industry sponsor and 121 are recruiting or about to. The newest, NCT07921966, was posted on November 6, 2026: Pharmacokinetics and Relative Bioavailability of Intranasal vs Intramuscular Olanzapine in Healthy Adult... (Neurelis, Inc.).

## The full list

New Bipolar Disorder clinical trials: 165 rows for $8.25, first posted on ClinicalTrials.gov from November 12, 2024 to November 9, 2026. Columns: NCT ID, Title, Sponsor, Sponsor class, Phase, Status, Conditions, Condition groups (MeSH), Interventions, Start date, First posted, Enrollment, Enrollment type, Location countries, Central contact, Contact phone, Contact email, Last update posted, Read on, Source. The new rows each week by email, about 7 rows a month: $19 a month. Pay by card with no account. Prices exclude VAT. CSV and Excel files with the columns this page does not show (central contact, contact phone, contact email, sponsor class, condition groups (MeSH), interventions and 5 more), which open on your screen as soon as the payment clears and come by email. The rows on this page are a sample.

Buy: https://specstream.ai/data/clinical-trials/condition/bipolar-disorder

SpecStream is the live web data engine for teams and agents. It reads every new study on ClinicalTrials.gov each morning, and this page is that reading. Ask for the conditions, phases or countries you follow and each new trial arrives in your sheet, CRM, Slack or agent with the sponsor, the sites and the listed contact.

- New trials: 165
- Industry sponsored: 18
- Recruiting or not yet: 121
- Latest posted: November 6, 2026

## Newest trials

The newest 100 of 165, each linked to its record. The full list holds every one with the sponsor class, interventions, start date and the central contact as the record prints it.

| First posted | NCT ID | Title | Sponsor | Phase | Status | Conditions | Enrollment | Countries | Source |
| --- | --- | --- | --- | --- | --- | --- | --- | --- | --- |
| November 6, 2026 | NCT07921966 | Pharmacokinetics and Relative Bioavailability of Intranasal vs Intramuscular Olanzapine in Healthy Adult Participants | Neurelis, Inc. | Phase 1 | Not yet recruiting | Healthy Adult Participants | 24 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07921966) |
| November 6, 2026 | NCT07921667 | Sleep Monitoring for Early Detection of Relapse in People With Schizophrenia or Bipolar Disorder Receiving Usual Treatment | International University of La Rioja | Observational | Not yet recruiting | Bipolar Disorder (BD), SCHIZOPHRENIA 1 (Disorder) | 30 | Spain | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07921667) |
| November 5, 2026 | NCT07920302 | Affective Cognitive Training in Mood Disorders and High-risk Relatives | Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital | Not applicable | Recruiting | Major Depressive Disorder (MDD), Bipolar Disorder (BD) | 100 | Denmark | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07920302) |
| November 3, 2026 | NCT07913542 | N-Acetylcysteine for Bipolar and Alcohol Use Disorders | Medical University of South Carolina | Phase 2 | Not yet recruiting | Bipolar Disorder, Alcohol Use Disorder | 70 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07913542) |
| November 2, 2026 | NCT07910318 | Neurostructural and Biochemical Signatures of Tobacco Smoking in Mood Disorders | Assiut University | Observational | Not yet recruiting | Major Depressive Disorder, Bipolar Disorder, Tobacco Use Disorder, Mood Disorders | 240 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07910318) |
| October 29, 2026 | NCT07905378 | Validation of Wearable Core Body Temperature-Based Circadian Rhythm Digital Biomarkers | Korea University Anam Hospital | Observational | Not yet recruiting | Mood Disorders, Major Depressive Diorder, Bipolar Disorders, Mental Disorder | 200 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07905378) |
| October 29, 2026 | NCT07903246 | A Prospective Study of Anxiety, Depression, and Bipolar Disorder in People | Second Affiliated Hospital, Zhejiang University, School of Medicine | Observational | Recruiting | Anxiety Disorders, Depressive Disorder, Bipolar Disorder (BD) | 2,690 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07903246) |
| October 22, 2026 | NCT07890805 | Evaluating the PolarUs App in People With Bipolar Disorder | University of British Columbia | Not applicable | Not yet recruiting | Bipolar Disorder (BD), Quality of Life (QOL) | 504 | Canada | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07890805) |
| October 19, 2026 | NCT07881016 | French Minds Cohort: a French Longitudinal and Multimodal Cohort of Patients With Major Mood Disorders, Psychotic Disorders, Autism... | Fondation FondaMental | Not applicable | Recruiting | Schizophrenia / Schizoaffective Disorder, First Episode Psychosis (FEP), Bipolar Disorder (BD), Major Depressive... | 3,000 | France | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07881016) |
| October 19, 2026 | NCT07880015 | Digital Phenotypes for Predicting Depression\_Validation | Korea University Anam Hospital | Observational | Enrolling by invitation | Major Depressive Disorder, Bipolar I Disorder, Bipolar II Disorder, Mood Disorders | 200 | South Korea | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07880015) |
| October 16, 2026 | NCT07879131 | A Mobile App to Support Mood, Daily Routines and Medication Adherence in Adults With Severe Mental Illness | Alexandria University | Not applicable | Not yet recruiting | Severe Mental Illness, Bipolar Disorder, Schizophrenia, Schizoaffective Disorder, Major Depressive Disorder | 60 | Bahrain | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07879131) |
| October 16, 2026 | NCT07879118 | Effect of Occupational Therapy on Psychosocial Parameters and Functioning in Individuals With Severe Mental Illness | Biruni University | Not applicable | Not yet recruiting | Schizophenia Disorder, Severe Mental Illness, Bipolar Disorder, Nonorganic Psychosis, Schizo-affective Disorder | 50 | Turkey (Türkiye) | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07879118) |
| October 14, 2026 | NCT07872878 | BAROMETRE : Study on the Prognosis and Course of Individuals With Bipolar Spectrum Disorder | University Hospital, Angers | Observational | Not yet recruiting | Bipolar Disorder (BD) | 60 | France | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07872878) |
| October 6, 2026 | NCT07860957 | Midday Bright Light Therapy for Bipolar Depression | Istanbul University - Cerrahpasa | Not applicable | Completed | Bipolar Disorder (BPD) | 37 | Turkey (Türkiye) | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07860957) |
| October 5, 2026 | NCT07858565 | Quality of Life, Safety and Compliance of Patients Using Monotherapy or Combinatorial Therapy With Quetiapine for Treatment of... | Bosnalijek D.D | Observational | Recruiting | Schizophrenia, Bipolar Affective Disorder | 500 | Bosnia and Herzegovina | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07858565) |
| September 28, 2026 | NCT07845409 | Targeted Alternating Current and Cognitive Training Intervention for Cognitive Control in Bipolar Disorders | VA Office of Research and Development | Not applicable | Not yet recruiting | Bipolar Disorder, Bipolar and Related Disorders, Veterans, Suicide, Suicidal Ideation, Mental Disorders | 138 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07845409) |
| September 22, 2026 | NCT07834112 | Body Weight Changes After Switching to Lurasidone for Antipsychotic-induced Weight Gain in Bipolar Disorder | Dong-Wook Kim | Observational | Completed | Bipolar Disorder (BD) | 155 | South Korea | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07834112) |
| September 22, 2026 | NCT07833267 | Cognition and Affective Research in China | Xuanwu Hospital, Beijing | Observational | Not yet recruiting | Neurodegenerative Disease, Dementia, Alzheimer's Disease, Parkinson's Disease, Mood Disorders, Depression, Anxiety... | 3,000 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07833267) |
| September 8, 2026 | NCT07806227 | Broadband Near Infrared Spectroscopy to Understand the Role of Brain Cytochrome C Oxidase in Bipolar Disorder | Martin Lan | Phase 4 | Not yet recruiting | Bipolar Disorder Depression | 60 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07806227) |
| August 25, 2026 | NCT07783633 | Identifying Biomarkers of Response to Digital Interventions for Mood Disorders | Centre for Addiction and Mental Health | Not applicable | Enrolling by invitation | Depression / Major Depressive Disorder, Bipolar Disorder (BD) | 200 | Canada | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07783633) |
| August 18, 2026 | NCT07771517 | Role of Kynurenine Pathway and Its Metabolites in Depressive Disorders, Major Depressive Disorder is Suspected to Have the Greatest Burden... | Sohag University | Observational | Not yet recruiting | Major Depressive Disorder (MDD) | 90 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07771517) |
| August 17, 2026 | NCT07767032 | Project MOVE Bipolar | Butler Hospital | Not applicable | Completed | Bipolar Disorder (BD) | 22 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07767032) |
| August 6, 2026 | NCT07748910 | Enhancing Resilience and Quality of Life in Bipolar Disorder Through Cognitive Behavioral Therapy | Cumhuriyet University | Not applicable | Completed | Bipolar Affective Disorder; Remission in | 22 | Turkey (Türkiye) | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07748910) |
| August 4, 2026 | NCT07745374 | Safety and Feasibility of DBS for Bipolar Depression | Icahn School of Medicine at Mount Sinai | Not applicable | Recruiting | Bipolar I Disorder, Bipolar Depression | 5 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07745374) |
| August 3, 2026 | NCT07741981 | Treatment Resistance in Psychiatric Disorders: the Search for Biological Markers Predictive of Response to Treatment | Centre Hospitalier St Anne | Not applicable | Recruiting | Schizophrenia, Treatment Resistant Depression (TRD), Bipolar Disorder (BD), Catatonia, Obsessive Compulsive Disorder... | 700 | France | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07741981) |
| July 31, 2026 | NCT07740694 | EEG Microstate and Neuroinflammatory Biomarkers in Older Age Patients With Major Depressive Disorder Receiving ECT | Istanbul University - Cerrahpasa | Observational | Recruiting | Major Depression Moderate, Major Depression Severe, Major Depression With Comorbid Anxiety Symptoms, Major Depression... | 62 | Turkey (Türkiye) | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07740694) |
| July 29, 2026 | NCT07733297 | The Effect of Cognitive Behavioral Psychoeducation on Internalized Stigma in Individuals With Bipolar Disorder | Eskisehir Osmangazi University | Not applicable | Completed | Bipolar Disorder (BD), Internalized Stigma, Psychoeducation | 43 | Turkey (Türkiye) | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07733297) |
| July 29, 2026 | NCT07732933 | Testing a New Gold Nanoparticle-Based Lithium Delivery Method for Bipolar Disorder in Laboratory Models | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | Not applicable | Not yet recruiting | Bipolar Disorder (BD), Bipolar Disorder (BPD) | 20 | Italy | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07732933) |
| July 13, 2026 | NCT07699445 | The Effects of Lumateperone on Obesity and Physiologic Aging and Their Association With Antidepressant Response in Bipolar Depression | Massachusetts General Hospital | Phase 4 | Recruiting | Bipolar Depression Depressed Phase, Obesity & Overweight | 25 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07699445) |
| July 9, 2026 | NCT07692984 | The Effect of Comorbid Alcohol/Substance Use | Abant Izzet Baysal University | Observational | Recruiting | Alcohol Abuse, Alcohol Use Disorder, Substance Use Disorders, Severe Mental Disorder, Schizophrenia, Bipolar Disorder... | 297 | Turkey (Türkiye) | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07692984) |
| July 6, 2026 | NCT07684911 | Longitudinal Study on the Sustainability of Transcranial Magnetic Stimulation Protocols - Biomarkers | Hospital Center Guillaume Régnier | Observational | Recruiting | Depression - Major Depressive Disorder, Depression Bipolar, Depression Unipolar | 30 | France | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07684911) |
| July 2, 2026 | NCT07680153 | Neuromodulation of Mood Switch Circuitry in Bipolar Disorder | Weill Medical College of Cornell University | Phase 4 | Recruiting | Bipolar Disorder (BD), Bipolar 1 Depression, rTMS, fMRI | 62 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07680153) |
| July 1, 2026 | NCT07679204 | Type D Personality and Life Satisfaction in Bipolar Disorder Type 2 and Major Depressive Disorder | Elazığ Mental Health and Diseases Hospital | Observational | Recruiting | Bipolar Disorder II, Major Depressive Disorder (MDD) | 180 | Turkey (Türkiye) | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07679204) |
| June 24, 2026 | NCT07664852 | Pramipexole vs Placebo Treatment in Bipolar Disorder With Anhedonic Depression | Daniel Lindqvist | Phase 3 | Recruiting | Bipolar Disorder (BD) | 126 | Sweden | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07664852) |
| June 17, 2026 | NCT07654348 | Efficacy and Mechanism of IPSRT for Bipolar II Disorder | First Affiliated Hospital of Zhejiang University | Phase 2 | Not yet recruiting | Bipolar Disorder II | 216 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07654348) |
| June 11, 2026 | NCT07643714 | Effects of ACT-Based Psychoeducation on Caregivers of Individuals With Mental Disorders | Zeynep Özkök | Not applicable | Completed | Caregiver Burden, Mental Disorders | 64 | Turkey (Türkiye) | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07643714) |
| June 8, 2026 | NCT07632989 | Virtual Reality-Based Cognitive Remediation in Schizophrenia and Bipolar Disorder | Università degli Studi di Brescia | Not applicable | Active not recruiting | Bipolar Disorder (BD), Schizophrenia Spectrum Disorders (SSD) | 80 | Italy | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07632989) |
| June 3, 2026 | NCT07622927 | FOCUS Bipolar: Families Opening Conversations for Understanding Signs | University of Texas Southwestern Medical Center | Observational | Recruiting | Bipolar Disorder (BD), Bipolar Disorder I or II, Bipolar Disorder Family Members, Screening Tool | 200 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07622927) |
| June 1, 2026 | NCT07619092 | Flumazenil for Benzodiazepine Reversal in Electroconvulsive Therapy | Anders Jørgensen | Not applicable | Recruiting | Depression - Major Depressive Disorder, Bipolar Disorder (BD), Functional Magnetic Resonance Imaging (fMRI), Cognition... | 145 | Denmark | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07619092) |
| May 18, 2026 | NCT07592884 | Rochester Forensic Assertive Community Treatment Model in Minnesota | University of Rochester | Not applicable | Completed | Schizophrenia, Bipolar Disorder, Criminal Behavior | 40 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07592884) |
| May 15, 2026 | NCT07589647 | Research on the Efficacy and Safety of Targeted Suprachiasmatic Nucleus Electrical Stimulation for Improving Metabolic Disorders in... | First Affiliated Hospital of Zhejiang University | Not applicable | Recruiting | Bipolar Disorder (BD) | 70 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07589647) |
| May 14, 2026 | NCT07586150 | Personalized Pharmaco-Lifestyle Interventions for Severe Mental Illnesses (LIFETRAIN) | Ludwig-Maximilians - University of Munich | Not applicable | Not yet recruiting | Severe Mental Illness, Depression / Major Depressive Disorder, Bipolar Disorder (BD), Schizophrenia | 140 | Austria, Germany, Netherlands | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07586150) |
| May 7, 2026 | NCT07573839 | An Exploratory Study on the Prediction of Recurrence Risk of Bipolar Disorder Using Sentiment Analysis Technology Based on Multi-modal... | Shanghai Mental Health Center | Observational | Recruiting | Bipolar Disorder (BD), Healthy Control | 400 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07573839) |
| May 6, 2026 | NCT07570875 | Evaluating the Impact of Ketogenic Therapy on Symptom Severity and Metabolic Side Effect Profile Among Individuals Living With Bipolar... | University of Alabama at Birmingham | Not applicable | Not yet recruiting | Bipolar Disorder | 100 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07570875) |
| May 6, 2026 | NCT07569198 | Ketamine With Dialectical Behavioural Therapy (DBT) for Suicidality in Individuals With Treatment-Resistant Depression and Borderline... | Joshua Rosenblat | Phase 2 | Recruiting | Borderline Personality Disorder (BPD), Treatment-Resistant Major Depressive Disorder, Treatment-resistant Bipolar... | 120 | Canada | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07569198) |
| April 29, 2026 | NCT07556861 | Senyo Health App - Comorbid Alcohol Use Disorder Treatment in Individuals With Bipolar Disorder Using a Telehealth Collaborative Care... | Mayo Clinic | Not applicable | Not yet recruiting | Bipolar Disorder | 40 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07556861) |
| April 29, 2026 | NCT07556692 | A Study of Home-use Brain Stimulation to Treat Bipolar Depression | King's College London | Not applicable | Recruiting | Bipolar Disorder (BD) | 212 | United Kingdom | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07556692) |
| April 24, 2026 | NCT07549581 | A Study of SEP-380135 in Adults With Schizophrenia or Major Depressive Episode | Otsuka Pharmaceutical Development & Commercialization, Inc. | Phase 1 | Completed | Schizophrenia, Major Depressive Disorder (MDD), Bipolar Disorder | 43 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07549581) |
| April 23, 2026 | NCT07548359 | Psychiatric Nursing Intervention for Caregivers of Patients With Bipolar Disorder | Menoufia University | Not applicable | Completed | Bipolar Disorder, Caregiver Burden, Psychological Resilience | 60 | Egypt | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07548359) |
| April 16, 2026 | NCT07534475 | Venous Tourniquet vs. Arterial Tourniquet for Seizure Monitoring in ECT | Medipol University | Not applicable | Recruiting | Major Depressive Disorder, Bipolar Disorder, Schizophrenia | 20 | Turkey (Türkiye) | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07534475) |
| April 3, 2026 | NCT07510646 | Transcranial Photobiomodulation for Bipolar Depression | Vielight Inc. | Not applicable | Not yet recruiting | Bipolar, Bipolar Disorder (BD), Bipolar Disorder Depression | 40 | Canada | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07510646) |
| March 31, 2026 | NCT07503275 | Functional Magnetic Resonance Imaging Study of Inhibitory Control in Bipolar Disorder and Major Depressive Disorder | CHU de Reims | Not applicable | Not yet recruiting | Bipolar Disorder, Major Depressive Disorder | 120 | France | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07503275) |
| March 18, 2026 | NCT07479758 | Biomarker Research on Ultra-High-Field MRI Combined With Visual Perception Assessment in the Diagnosis and Treatment Outcomes of Severe... | Second Affiliated Hospital, Zhejiang University, School of Medicine | Observational | Recruiting | Major Depressive Disorder (MDD), Schizophrenia, Bipolar Disorder, Severe Mental Disorders | 320 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07479758) |
| March 16, 2026 | NCT07472920 | Empagliflozin Adjunctive Therapy in Bipolar Depression | University of Sao Paulo | Not applicable | Not yet recruiting | Bipolar Disorder, Bipolar Depression, Insulin Resistance | 20 | Brazil | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07472920) |
| March 16, 2026 | NCT07472075 | Melatonin Versus Placebo for Bipolar Disorder | Lars Vedel Kessing | Phase 2 | Recruiting | Bipolar Affective Disorder | 200 | Denmark | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07472075) |
| March 11, 2026 | NCT07463911 | Treatment Response In ECT Patients | Nurdan Sağbaş | Observational | Active not recruiting | Major Depression, Bipolar Affective Disorder, Bipolar Depression Depressed Phase | 65 | Turkey (Türkiye) | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07463911) |
| March 3, 2026 | NCT07445802 | Medication Adherence in Severe Mental Illness: a Promotion Program | Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz | Not applicable | Not yet recruiting | Treatment Adherence and Compliance, Severe Mental Disorders, Bipolar Disorder (BD), Schizophrenia Disorder | 1,640 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07445802) |
| March 3, 2026 | NCT07444463 | Brain Network Mechanisms of Cognitive Impairments in Major Psychiatric Disorders and Their Clinical Applications | Central South University | Not applicable | Not yet recruiting | Schizophrenia, Bipolar Disorder, Major Depressive Disorder (MDD) | 400 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07444463) |
| February 27, 2026 | NCT07437833 | Psychophysiological Responses to Six Single-Session Self-Regulation Interventions in a Female Adult With ADHD and Stabilized Bipolar... | Poznan University of Physical Education | Not applicable | Recruiting | ADHD - Attention Deficit Disorder With Hyperactivity, Bipolar Affective Disorder; Remission in | 1 | Poland | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07437833) |
| February 25, 2026 | NCT07434414 | LRFN5 and OLFM4 in Bipolar Disorder | Elazığ Mental Health and Diseases Hospital | Observational | Completed | Bipolar Disorder (BD) | 72 | Turkey (Türkiye) | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07434414) |
| February 23, 2026 | NCT07427966 | Psychobiological Markers to Improve Diagnosis and to Predict Affective Episodes in Bipolar Disorder | Karolinska Institutet | Observational | Not yet recruiting | Major Depressive Disorder, Mood Disorders, Bipolar Disorder (BD) | 600 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07427966) |
| February 17, 2026 | NCT07414147 | TMS for Improving Cognitive Function in Bipolar Disorder | First Affiliated Hospital of Zhejiang University | Not applicable | Not yet recruiting | Bipolar Disorder (BD), Cognitive Impairment | 88 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07414147) |
| February 17, 2026 | NCT07412132 | Evaluation of the Efficacy, Safety, and Tolerability of Lacosamide in Major Depressive Episodes of Bipolar Disorder Types I and II. | University of Sao Paulo | Phase 3 | Recruiting | Bipolar Affective Disorder | 40 | Brazil | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07412132) |
| February 13, 2026 | NCT07411222 | Emotional Eating, Sleep Quality, Mental State and Metabolic Syndrome | Abant Izzet Baysal University | Observational | Recruiting | Schizophrenia, Bipolar Disorder, Psychiatric Issue, Metabolic Syndrome, Emotional Eating, Sleep, Mediating | 78 | Turkey (Türkiye) | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07411222) |
| February 12, 2026 | NCT07404943 | The Effect of Telenursing on Functionality and Treatment Adherence in Bipolar Disorder | Didem Ayhan | Not applicable | Completed | Bi-Polar Disorder | 70 | Turkey (Türkiye) | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07404943) |
| February 11, 2026 | NCT07404085 | Epigenetic Enhancement of Cognitive Training in Aging Mood and Schizophrenia Spectrum Disorder Populations | Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital | Not applicable | Recruiting | Bipolar Disorder (BD), Depression - Major Depressive Disorder, Cognitive Impairment, Schizophrenia Disorders | 160 | Denmark | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07404085) |
| February 10, 2026 | NCT07399626 | Adaptation and Validation of the Hypomanic Personality Scale (HPS-6) to Romanian | Babes-Bolyai University | Phase 1/2 | Recruiting | Bipolar Disorder (BD) | 50 | Romania | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07399626) |
| February 9, 2026 | NCT07398365 | Medical Phenotyping of NHS General Adult Psychiatry (GAP) Inpatients | University of Edinburgh | Observational | Recruiting | Bipolar Affective Disorder, Schizophrenia Disorders, Depression Disorders, Personality Disorders | 100 | United Kingdom | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07398365) |
| February 9, 2026 | NCT07396363 | Psychoeducational Psychotherapy in Adolescent Bipolar Disorder | Dokuz Eylul University | Not applicable | Completed | Bipolar Disorder (BD) | 32 | Turkey (Türkiye) | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07396363) |
| February 5, 2026 | NCT07389473 | Evaluate the Effects of Long-term Use of Psychotropic Medications on Eye Movement Patterns With the Gaize Device | Gaize | Observational | Recruiting | ADHD, Depression Disorders, Mood Disorders, Anxiety Disorder Generalized, Bipolar Disorder (BPD) | 50 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07389473) |
| January 15, 2026 | NCT07343739 | Bipolar Disorder Integrative Staging: Incorporating Biomarkers Into Progression Across Stages | ASST Fatebenefratelli Sacco | Observational | Active not recruiting | Bipolar Disorder | 126 | Italy | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07343739) |
| January 13, 2026 | NCT07337889 | Conceptualizing Borderline Personality Disorder as a Relationship Use Disorder | University Hospital, Montpellier | Not applicable | Recruiting | Borderline Personality Disorder, Borderline Personality Disorder (BPD), Bipolar Disorder (BD) | 194 | France | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07337889) |
| January 9, 2026 | NCT07329673 | An Examination of the Performance of QbMobile in Differential Diagnosis Associated With ADHD Symptoms | Qbtech AB | Observational | Suspended | Bi-Polar Disorder, Autism Spectrum Disorder (ASD), Major Depression Disorders, Separation Anxiety Disorder, Social... | 300 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07329673) |
| January 5, 2026 | NCT07316803 | Group Intervention for Romantic Relationships in Young Adults With Severe Mental Illness | Centre hospitalier de Ville-Evrard, France | Not applicable | Recruiting | Severe Mental Illness, Schizophrenia, Bipolar Disorder, Major Depressive Disorder | 20 | France | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07316803) |
| December 29, 2025 | NCT07306468 | Effects of Schizophrenia and Bipolar Disorder on Exercise Capacity, Pulmonary Function, and Quality of Life | Çankırı Karatekin University | Observational | Recruiting | Schizophenia Disorder, Bipolar Disorder (BD) | 150 | Turkey (Türkiye) | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07306468) |
| December 29, 2025 | NCT07306039 | Feasibility of eLi12 | Ole Köhler-Forsberg | Not applicable | Active not recruiting | Bipolar Disorder (BD) | 200 | Denmark | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07306039) |
| December 23, 2025 | NCT07298278 | Anticipating Depressive and Manic Episodes in Bipolar Disorders Using Vocal Biomarkers | Centre Hospitalier St Anne | Not applicable | Not yet recruiting | Bipolar Disorder (BD) | 170 |  | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07298278) |
| December 22, 2025 | NCT07297056 | Mindfulness Psychoeducation for Bipolar Disorder | Ömer USLU | Not applicable | Completed | Bipolar Disorder (BD), Mindfulness-Based Stress Reduction, Mindfulness Meditation | 40 | Turkey (Türkiye) | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07297056) |
| December 19, 2025 | NCT07295652 | Characterization of High-Level Cognitive Impairments in Patients With Neuropsychiatric Disorders | Centre Hospitalier St Anne | Not applicable | Recruiting | Neurologic Disorders, Schizophrenia, Bipolar Disorder (BD), Depressive Disorder | 600 | France | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07295652) |
| December 16, 2025 | NCT07286175 | A Study of Brenipatide in Adult Participants With Bipolar Disorder (RENEW-Bipolar-1) | Eli Lilly and Company | Phase 2 | Recruiting | Bipolar Disorder | 400 | Argentina, Brazil, China, India, Japan, Mexico, Puerto Rico, United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07286175) |
| December 5, 2025 | NCT07266545 | RNA Editing as a Biomarker of Antidepressant Response in Unipolar and Bipolar Depression (EDIT-ANDRE) | Mayo Clinic | Phase 4 | Recruiting | Unipolar Depression, Bipolar Depression | 120 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07266545) |
| December 4, 2025 | NCT07263191 | A Study of Olanzapine in Participants With Bipolar Disorder. | Boryung Pharmaceutical Co., Ltd | Observational | Recruiting | Bipolar Disorder | 3,000 | South Korea | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07263191) |
| November 25, 2025 | NCT07247344 | Multimodal Phenotyping in Adolescent Inpatient Depression: An Observational Study | Jiangsu Province Nanjing Brain Hospital | Observational | Recruiting | Adolescent, Major Depressive Disorder (MDD, Bipolar Disorder (BD) | 1,000 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07247344) |
| November 24, 2025 | NCT07246044 | HD-tDCS for Adolescent Bipolar Depression Targeting S1 | Jiangsu Province Nanjing Brain Hospital | Not applicable | Recruiting | Adolescent, Bipolar Depression, tDCS, Primary Somatosensory Cortex, Bipolar Disorder Depression | 100 | China | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07246044) |
| November 20, 2025 | NCT07239778 | The PEDAL Intervention - Reducing Affective Lability in Bipolar Disorder | Oslo University Hospital | Phase 2 | Recruiting | Bipolar Disorder (BD) | 120 | Norway | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07239778) |
| November 19, 2025 | NCT07234851 | Understanding Mechanisms of Synaptic Degeneration Underlying Clinical Symptoms in Patients With MDs and NDs. | Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau | Observational | Enrolling by invitation | Schizophrenia Disorder, Frontotemporal Dementia, Behavioral Variant, Major Depressive Disorder (MDD), Bipolar Disorder... | 150 | Spain | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07234851) |
| October 28, 2025 | NCT07221864 | Decoding Emotional Dynamics in Bipolar Disorder | Laureate Institute for Brain Research, Inc. | Not applicable | Recruiting | Bipolar Disorder I or II, Healthy (Controls) | 72 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07221864) |
| October 20, 2025 | NCT07217860 | An Open-label Study of Azetukalner in Bipolar I or II Depression (X-CEED-OLE) | Xenon Pharmaceuticals Inc. | Phase 3 | Active not recruiting | Bipolar Depression, Bipolar I Disorder, Bipolar Disorder, Bipolar II Disorder | 400 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07217860) |
| October 9, 2025 | NCT07213492 | Multimodal Intervention to Support Hospital-to-Community Transition in Bipolar Disorder | McMaster University | Not applicable | Recruiting | Bipolar Disorder (BD), Psychosis | 10 | Canada | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07213492) |
| October 9, 2025 | NCT07213466 | Individualized Pharmacological Approach to Obesity in Patients With Bipolar Disorder | Mayo Clinic | Phase 4 | Recruiting | Bipolar I Disorder, Bipolar II Disorder, Schizo Affective Disorder, Obesity, Weight Loss, GLP - 1 | 100 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07213466) |
| October 8, 2025 | NCT07212075 | Precision Subclassification of Mental Health in Diabetes: Digital Twins for Precision Mental Health to Track Subgroups | Forschungsinstitut der Diabetes Akademie Mergentheim | Observational | Recruiting | Diabetes (DM), Diabete Mellitus, Diabete Type 1, Diabete Type 2, Diabetes Distress, Diabetes Complications, Depression... | 1,809 | Germany | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07212075) |
| October 8, 2025 | NCT07211750 | Integrated Care for Older Adults With Major Depression and Physical Multimorbidity - The I-CONNECT | KU Leuven | Not applicable | Recruiting | Multimorbidity, Older Adults (65 Years and Older), Mood Disorders, Depression - Major Depressive Disorder, Bipolar... | 82 | Belgium | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07211750) |
| October 7, 2025 | NCT07211217 | Time Restricted Eating (TRE) in Bipolar Disorder | Massachusetts General Hospital | Not applicable | Recruiting | Bipolar Disorder (BD), Bipolar Disorder Depression, Overweight (BMI \> 30) | 40 | United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07211217) |
| September 24, 2025 | NCT07189689 | Mental Health Mission Mood Disorder Cohort Study | University of Oxford | Observational | Not yet recruiting | Depression - Major Depressive Disorder, Depression Bipolar, Treatment Resistant Depression | 2,000 | United Kingdom | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07189689) |
| September 15, 2025 | NCT07173842 | NeuroPsyBiT-BD Omics: Genomic & Epigenomic Biobank of Bipolar Disorder | Selçuk State Hospital | Observational | Not yet recruiting | Bipolar Disorder | 1,000 | Turkey (Türkiye) | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07173842) |
| September 15, 2025 | NCT07172516 | A Randomized Study of Azetukalner Versus Placebo in Depressive Episodes Associated With Bipolar I or II Disorder (Bipolar Depression) | Xenon Pharmaceuticals Inc. | Phase 3 | Active not recruiting | Bipolar Disorder, Bipolar Depression, Bipolar I Disorder, Bipolar II Disorder | 400 | Bulgaria, Germany, Spain, United States | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07172516) |
| September 11, 2025 | NCT07167563 | Real-world Lithium Intake | University of Aarhus | Observational | Recruiting | Bipolar Disorder (BD) | 50 | Denmark | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07167563) |
| September 3, 2025 | NCT07151846 | Digital Phenotypes for Predicting Depression | Korea University Anam Hospital | Observational | Enrolling by invitation | Depression - Major Depressive Disorder, Depression Bipolar, Bipolar Disorder (BD), Mood Disorders | 540 | South Korea | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07151846) |
| August 26, 2025 | NCT07140913 | A Study to Evaluate the Efficacy and Safety of Adjunctive KarXT for the Treatment of Mania, With or Without Mixed Features, in Participants... | Bristol-Myers Squibb | Phase 3 | Recruiting | Mania, Bipolar Disorder | 424 | Argentina, Bulgaria, China, Denmark, France, India, Israel, Italy, Japan... | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07140913) |
| August 24, 2025 | NCT07140042 | Physical Fitness, Physical Activity Level, Depression and Quality of Life in Bipolar and Schizophrenia Patients | Dr. Lutfi Kirdar Kartal Training and Research Hospital | Observational | Completed | Bipolar Disorder (BD), Schizophrenia Disorder | 62 | Turkey (Türkiye) | [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07140042) |

## Sponsors posting most

| Sponsor | New trials | Latest |
| --- | --- | --- |
| First Affiliated Hospital of Zhejiang University | 5 | June 17, 2026 |
| Mayo Clinic | 5 | April 29, 2026 |
| Centre Hospitalier St Anne | 4 | August 3, 2026 |
| Korea University Anam Hospital | 3 | October 29, 2026 |
| VA Office of Research and Development | 3 | September 28, 2026 |
| Shanghai Mental Health Center | 3 | May 7, 2026 |
| Peking University | 3 | June 5, 2025 |
| Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital | 2 | November 5, 2026 |
| Assiut University | 2 | November 2, 2026 |
| Second Affiliated Hospital, Zhejiang University, School of Medicine | 2 | October 29, 2026 |
| University of British Columbia | 2 | October 22, 2026 |
| Istanbul University - Cerrahpasa | 2 | October 6, 2026 |
| Butler Hospital | 2 | August 17, 2026 |
| Massachusetts General Hospital | 2 | July 13, 2026 |
| Abant Izzet Baysal University | 2 | July 9, 2026 |
| Hospital Center Guillaume Régnier | 2 | July 6, 2026 |
| Elazığ Mental Health and Diseases Hospital | 2 | July 1, 2026 |
| University of Rochester | 2 | May 18, 2026 |
| King's College London | 2 | April 29, 2026 |
| CHU de Reims | 2 | March 31, 2026 |

## By phase

| Phase | New trials | Latest |
| --- | --- | --- |
| [Not applicable](https://specstream.ai/data/clinical-trials/phase/not-applicable) | 81 | November 5, 2026 |
| [Observational](https://specstream.ai/data/clinical-trials/phase/observational) | 53 | November 6, 2026 |
| [Phase 2](https://specstream.ai/data/clinical-trials/phase/phase-2) | 11 | November 3, 2026 |
| [Phase 4](https://specstream.ai/data/clinical-trials/phase/phase-4) | 8 | September 8, 2026 |
| [Phase 3](https://specstream.ai/data/clinical-trials/phase/phase-3) | 6 | June 24, 2026 |
| [Phase 1](https://specstream.ai/data/clinical-trials/phase/phase-1) | 4 | November 6, 2026 |
| [Phase 1/2](https://specstream.ai/data/clinical-trials/phase/phase-1-2) | 1 | February 10, 2026 |
| [Early phase 1](https://specstream.ai/data/clinical-trials/phase/early-phase-1) | 1 | December 13, 2024 |

## By country

| Country | New trials | Latest |
| --- | --- | --- |
| [United States](https://specstream.ai/data/clinical-trials/country/united-states) | 45 | November 3, 2026 |
| [Turkey (Türkiye)](https://specstream.ai/data/clinical-trials/country/turkey-t-rkiye) | 22 | October 16, 2026 |
| [China](https://specstream.ai/data/clinical-trials/country/china) | 19 | October 29, 2026 |
| [France](https://specstream.ai/data/clinical-trials/country/france) | 16 | October 19, 2026 |
| [Canada](https://specstream.ai/data/clinical-trials/country/canada) | 11 | October 22, 2026 |
| [Denmark](https://specstream.ai/data/clinical-trials/country/denmark) | 9 | November 5, 2026 |
| [Italy](https://specstream.ai/data/clinical-trials/country/italy) | 5 | July 29, 2026 |
| [United Kingdom](https://specstream.ai/data/clinical-trials/country/united-kingdom) | 5 | April 29, 2026 |
| [Spain](https://specstream.ai/data/clinical-trials/country/spain) | 4 | November 6, 2026 |
| [South Korea](https://specstream.ai/data/clinical-trials/country/south-korea) | 4 | October 19, 2026 |
| [Germany](https://specstream.ai/data/clinical-trials/country/germany) | 4 | May 14, 2026 |
| [Brazil](https://specstream.ai/data/clinical-trials/country/brazil) | 3 | March 16, 2026 |
| [Sweden](https://specstream.ai/data/clinical-trials/country/sweden) | 2 | June 24, 2026 |
| [Austria](https://specstream.ai/data/clinical-trials/country/austria) | 2 | May 14, 2026 |
| [Poland](https://specstream.ai/data/clinical-trials/country/poland) | 2 | February 27, 2026 |
| [Romania](https://specstream.ai/data/clinical-trials/country/romania) | 2 | February 10, 2026 |
| [Argentina](https://specstream.ai/data/clinical-trials/country/argentina) | 2 | December 16, 2025 |
| [India](https://specstream.ai/data/clinical-trials/country/india) | 2 | December 16, 2025 |
| [Japan](https://specstream.ai/data/clinical-trials/country/japan) | 2 | December 16, 2025 |
| [Norway](https://specstream.ai/data/clinical-trials/country/norway) | 2 | November 20, 2025 |
| [Bulgaria](https://specstream.ai/data/clinical-trials/country/bulgaria) | 2 | September 15, 2025 |
| [Israel](https://specstream.ai/data/clinical-trials/country/israel) | 2 | August 26, 2025 |
| Bahrain | 1 | October 16, 2026 |
| [Bosnia and Herzegovina](https://specstream.ai/data/clinical-trials/country/bosnia-and-herzegovina) | 1 | October 5, 2026 |
| [Netherlands](https://specstream.ai/data/clinical-trials/country/netherlands) | 1 | May 14, 2026 |

## Where the register publishes

- [ClinicalTrials.gov](https://clinicaltrials.gov/)
- [ClinicalTrials.gov API](https://clinicaltrials.gov/data-api/api)

Source: [ClinicalTrials.gov API v2 (U.S. National Library of Medicine)](https://clinicaltrials.gov/data-api/api). U.S. government data; ClinicalTrials.gov terms of use. Studies are as their sponsors registered them on ClinicalTrials.gov, read through its API. Condition groups are the MeSH terms ClinicalTrials.gov assigns to each study's conditions; a study with several is in several groups. Sponsor class is the register's class of the lead sponsor. The central contact is in the full list only as the record prints it.

Free to reuse with credit to SpecStream under [CC BY 4.0](https://creativecommons.org/licenses/by/4.0/).